Through our research on cancer genomes as well as the genomes of people with and without cancer we are advancing our understanding of the etiology of cancer; cancer prevention, screening, and diagnosis; germline genetic variations and gene expression; lifestyle factors and the cancer genome; and environmental factors and the cancer genome.
This work includes:
- Studies made possible by a comprehensively genotyped cohort of over 100,000 Kaiser Permanente Northern California members enrolled in our Research Program on Genes, Environment, and Health.
- Research on archived pathology specimens on over 400,000 cancer cases dating back to the 1940s.
- Exploring the role of genetic factors, ancestry, and lifestyle on skin cancer.
- Identifying genes tied to breast cancer treatment outcomes.