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Behavioral Health and Aging Publications


Psychotropic medication prescribing during the COVID-19 pandemic

This study examined changes in psychotropic medication use associated with the early months of the coronavirus disease 2019 (COVID-19) pandemic. Using Kaiser Permanente Northern California electronic health records, the authors identified adult patients w...
Author(s): Hirschtritt ME; Slama N; Sterling SA; Olfson M; Iturralde E

Medicine (Baltimore). 2021 Oct 29;100(43):e27664.

PubMed abstract

Marginal structural models for life-course theories and social epidemiology: Definitions, sources of bias, and simulated illustrations

Social epidemiology aims to identify social structural risk factors thus informing targets and timing of interventions. Ascertaining which interventions will be most effective and when they should be implemented is challenging because social conditions va...
Author(s): Gilsanz P; Young JG; Glymour MM; Tchetgen Tchetgen EJ; Eng CW; Koenen KC; Kubzansky LD

Am J Epidemiol. 2021 Oct 20.

PubMed abstract

Opportunities to Integrate Mobile App-Based Interventions Into Mental Health and Substance Use Disorder Treatment Services in the Wake of COVID-19

The COVID-19 pandemic has heightened concerns about the impact of depression, anxiety, alcohol, and drug use on public health. Mobile apps to address these problems were increasingly popular even before the pandemic, and may help reach people who otherwis...
Author(s): Satre DD; Meacham MC; Asarnow LD; Fisher WS; Fortuna LR; Iturralde E

Am J Health Promot. 2021 Oct 15:8901171211055314.

PubMed abstract

Rates of Prenatal Cannabis Use Among Pregnant Women Before and During the COVID-19 Pandemic

Author(s): Young-Wolff KC; Ray GT; Alexeeff SE; Adams SR; Does MB; Ansley D; Avalos LA

JAMA. 2021 Sep 27.

PubMed abstract

Patient and provider factors associated with receipt and delivery of brief interventions for unhealthy alcohol use in primary care

Unhealthy alcohol use is a serious and costly public health problem. Alcohol screening and brief interventions are effective in reducing unhealthy alcohol consumption. However, rates of receipt and delivery of brief interventions vary significantly across...
Author(s): Lu Y; Metz VE; Weisner C; Campbell CI; Sterling SA; et al.

Alcohol Clin Exp Res. 2021 Sep 05.

PubMed abstract

Emergency Department Encounters Among Youth With Suicidal Thoughts or Behaviors During the COVID-19 Pandemic

Population-level reports of suicide-related emergency department (ED) encounters among youth during the COVID-19 pandemic are lacking, along with youth characteristics and preexisting psychiatric service use. To characterize population-level and relative ...
Author(s): Ridout KK; Alavi M; Ridout SJ; Koshy MT; Awsare S; Harris B; Vinson DR; Weisner CM; Sterling S; Iturralde E

JAMA Psychiatry. 2021 Sep 01.

PubMed abstract

New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis

Migraine is a common disabling primary headache disorder that is ranked as the most common neurological cause of disability worldwide. Women present with migraine much more frequently than men, but the reasons for this difference are unknown. Migraine her...
Author(s): Choquet H; Yin J; Jacobson AS; Horton BH; Hoffmann TJ; Jorgenson E; Avins AL; Pressman AR

Commun Biol. 2021 Jul 22;4(1):864. Epub 2021-07-22.

PubMed abstract

Engagement in perinatal depression treatment: a qualitative study of barriers across and within racial/ethnic groups

To better understand previously observed racial/ethnic disparities in perinatal depression treatment rates we examined care engagement factors across and within race/ethnicity. Obstetric patients and women's health clinician experts from a large healthcar...
Author(s): Iturralde E; Hsiao CA; Nkemere L; Kubo A; Sterling SA; Flanagan T; Avalos LA

BMC Pregnancy Childbirth. 2021 Jul 16;21(1):512. Epub 2021-07-16.

PubMed abstract

Impact of 2012 Prostate Cancer Screening Statement

Author(s): Presti J; Alexeeff S; Avins AL

J Gen Intern Med. 2021 Jul 13.

PubMed abstract

Hereditary Spherocytosis

Hereditary spherocytosis (HS) is the most prevalent cause of hemolytic anemia due to an abnormal red cell membrane and classifies as a type of congenital hemolytic anemia. Oskar Minkowsky first described it in the early 1900s.[1] Erythrocytes are unable t...
Author(s): Zamora EA; Schaefer CA

Treasure Island (FL): StatPearls Publishing; 2021.

PubMed abstract

Physical, Mental Health and Developmental Conditions, and Sociodemographic Characteristics Associated With Adverse Childhood Experiences Among Young Children in Pediatric Primary Care

To examine associations between patient characteristics and adverse childhood experiences (ACEs) in a population-based sample of pediatric primary care patients, using electronic health records and clinical, administrative data. An observational study was...
Author(s): Sterling S; Iturralde E; Young-Wolff K; Metz VE; Espinas P; et al.

J Pediatr Health Care. 2021 Jul 02.

PubMed abstract

Why do Americans use marijuana?

Marijuana is the most commonly used illicit drug in the United States; yet, little is known about why adults use it. We examined the prevalence of past-month marijuana use by users' reasons for use-medical, recreational, and both-and identified correlates...
Author(s): Kurtzman ET; Young-Wolff KC

Drug Alcohol Depend. 2021 Jun 29;226:108880. Epub 2021-06-29.

PubMed abstract

Participant education, spousal education and dementia risk in a diverse cohort of members of an integrated health care delivery system in Northern California

The role of spousal education on dementia risk and how it may differ by gender or race/ethnicity is unknown. This study examines the association between one's own education separate from and in conjunction with spousal education and risk of dementia. Coho...
Author(s): Gilsanz P; Mayeda ER; Eng CW; Meyer OL; Glymour MM; Quesenberry CP; Whitmer RA

BMJ Open. 2021 06 18;11(6):e040233. Epub 2021-06-18.

PubMed abstract

A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects

Cataract is the leading cause of blindness among the elderly worldwide and cataract surgery is one of the most common operations performed in the United States. As the genetic etiology of cataract formation remains unclear, we conducted a multiethnic geno...
Author(s): Choquet H; 23andMe Research Team; Jorgenson E; et al.

Nat Commun. 2021 06 14;12(1):3595. Epub 2021-06-14.

PubMed abstract

Attention-Deficit/Hyperactivity Disorder Medication Adherence in the Transition to Adulthood: Associated Adverse Outcomes for Females and Other Disparities

The purpose of this study was to assess the association between attention-deficit/hyperactivity disorder (ADHD) medication adherence and adverse health outcomes in older adolescents transitioning to adulthood. In a cohort of 17-year-old adolescents with A...
Author(s): Rao K; Carpenter DM; Campbell CI

J Adolesc Health. 2021 May 28.

PubMed abstract

Predicting adolescent alcohol and other drug problems using electronic health records data

Alcohol and other drug (AOD) use problems may cause significant burden on affected adolescents and their families, yet treatment providers often do not identify these problems early enough. To develop, and internally and externally validate a multivariabl...
Author(s): Chi FW; Alexeeff S; Ahmedani B; Boscarino JA; Waitzfelder B; Dugan R; Frankland T; Hu Y; Loree A; Sterling S

J Subst Abuse Treat. 2021 May 21;132:108487. Epub 2021-05-21.

PubMed abstract

Prospective validation of the Kaiser Permanente prostate cancer risk calculator in a contemporary, racially diverse, referral population

To prospectively validate a new prostate cancer risk calculator in a racially diverse population. We recently developed, internally validated and published the Kaiser Permanente Prostate Cancer Risk Calculator. This study is a prospective validation of th...
Author(s): Presti JC; Alexeeff S; Horton B; Prausnitz S; Avins AL

Urol Oncol. 2021 May 04.

PubMed abstract

Engaging patients in population-based chronic disease management: A qualitative study of barriers and intervention opportunities

Cardiovascular disease (CVD) continues to be a leading cause of morbidity in the U.S. Managing CVD risk factors, such as diabetes or hypertension, can be challenging for many individuals. We investigated the barriers experienced by patients who persistent...
Author(s): Fang A; Abdelgadir D; Gopalan A; Ross T; Uratsu CS; Sterling SA; Grant RW; Iturralde E

Patient Educ Couns. 2021 May 04.

PubMed abstract

PRimary Care Opioid Use Disorders treatment (PROUD) trial protocol: a pragmatic, cluster-randomized implementation trial in primary care for opioid use disorder treatment

Most people with opioid use disorder (OUD) never receive treatment. Medication treatment of OUD in primary care is recommended as an approach to increase access to care. The PRimary Care Opioid Use Disorders treatment (PROUD) trial tests whether implement...
Author(s): Campbell CI; Bradley KA; et al.

Addict Sci Clin Pract. 2021 Jan 31;16(1):9. Epub 2021-01-31.

PubMed abstract

Changes in Diagnostic and Demographic Characteristics of Patients Seeking Mental Health Care During the Early COVID-19 Pandemic in a Large, Community-Based Health Care System

The early COVID-19 pandemic resulted in great psychosocial disruption and stress, raising speculation that psychiatric disorders may worsen. This study aimed to identify patients vulnerable to worsening mental health during the COVID-19 pandemic. This ret...
Author(s): Ridout KK; Alavi M; Ridout SJ; Koshy MT; Harris B; Dhillon I; Awsare S; Weisner CM; Campbell CI; Iturralde E

J Clin Psychiatry. 2021 03 03;82(2). Epub 2021-03-03.

PubMed abstract

Association of Cannabis Retailer Proximity and Density With Cannabis Use Among Pregnant Women in Northern California After Legalization of Cannabis for Recreational Use

Author(s): Young-Wolff KC; Adams SR; Padon A; Silver LD; Alexeeff SE; Van Den Eeden SK; Avalos LA

JAMA Netw Open. 2021 Mar 01;4(3):e210694. Epub 2021-03-01.

PubMed abstract

Association of Pregnancy Intentions With Substance Use During Early Pregnancy

The goal of this study was to evaluate the association between pregnancy intentions and substance use in early pregnancy among pregnant women receiving prenatal care in a large, integrated healthcare system. The sample comprised 29,787 Kaiser Permanente N...
Author(s): Young-Wolff KC; Slama N; Sarovar V; Conway A; Tucker LY; Goler N; Terplan M; Ansley D; Adams SR; Armstrong MA

J Addict Med. 2021 Feb 16.

PubMed abstract

Cigarette smoking behaviors and the importance of ethnicity and genetic ancestry

Cigarette smoking contributes to numerous diseases and is one of the leading causes of death in the United States. Smoking behaviors vary widely across race/ethnicity, but it is not clear why. Here, we examine the contribution of genetic ancestry to varia...
Author(s): Choquet H; Yin J; Jorgenson E

Transl Psychiatry. 2021 Feb 11;11(1):120. Epub 2021-02-11.

PubMed abstract

Adverse Childhood Experiences and Early and Continued Breastfeeding: Findings from an Integrated Health Care Delivery System

Purpose: To examine whether adverse childhood experiences (ACEs) are associated with breastfeeding behaviors. Methods: Women in three Kaiser Permanente Northern California medical centers were screened for ACEs during standard prenatal care (N = 926). Mul...
Author(s): Watson C; Wei J; Varnado N; Rios N; Flanagan T; Alabaster A; Staunton M; Sterling SA; Gunderson E; Young-Wolff KC

J Womens Health (Larchmt). 2021 Feb 04.

PubMed abstract

Closing the gap: Identification and management of familial hypercholesterolemia in an integrated healthcare delivery system

Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder that causes markedly elevated risk for early onset coronary artery disease. Despite availability of effective therapy, only 5-10% of affected individuals worldwide are diagnosed....
Author(s): Birnbaum RA; Horton BH; Gidding SS; Brenman LM; Macapinlac BA; Avins AL

J Clin Lipidol. 2021 Feb 02.

PubMed abstract