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Behavioral Health and Aging Publications


New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis

Migraine is a common disabling primary headache disorder that is ranked as the most common neurological cause of disability worldwide. Women present with migraine much more frequently than men, but the reasons for this difference are unknown. Migraine her...
Author(s): Choquet H; Yin J; Jacobson AS; Horton BH; Hoffmann TJ; Jorgenson E; Avins AL; Pressman AR

Commun Biol. 2021 Jul 22;4(1):864. Epub 2021-07-22.

PubMed abstract

Engagement in perinatal depression treatment: a qualitative study of barriers across and within racial/ethnic groups

To better understand previously observed racial/ethnic disparities in perinatal depression treatment rates we examined care engagement factors across and within race/ethnicity. Obstetric patients and women's health clinician experts from a large healthcar...
Author(s): Iturralde E; Hsiao CA; Nkemere L; Kubo A; Sterling SA; Flanagan T; Avalos LA

BMC Pregnancy Childbirth. 2021 Jul 16;21(1):512. Epub 2021-07-16.

PubMed abstract

Impact of 2012 Prostate Cancer Screening Statement

Author(s): Presti J; Alexeeff S; Avins AL

J Gen Intern Med. 2021 Jul 13.

PubMed abstract

Hereditary Spherocytosis

Hereditary spherocytosis (HS) is the most prevalent cause of hemolytic anemia due to an abnormal red cell membrane and classifies as a type of congenital hemolytic anemia. Oskar Minkowsky first described it in the early 1900s.[1] Erythrocytes are unable t...
Author(s): Zamora EA; Schaefer CA

Treasure Island (FL): StatPearls Publishing; 2021.

PubMed abstract

Physical, Mental Health and Developmental Conditions, and Sociodemographic Characteristics Associated With Adverse Childhood Experiences Among Young Children in Pediatric Primary Care

To examine associations between patient characteristics and adverse childhood experiences (ACEs) in a population-based sample of pediatric primary care patients, using electronic health records and clinical, administrative data. An observational study was...
Author(s): Sterling S; Iturralde E; Young-Wolff K; Metz VE; Espinas P; et al.

J Pediatr Health Care. 2021 Jul 02.

PubMed abstract

Why do Americans use marijuana?

Marijuana is the most commonly used illicit drug in the United States; yet, little is known about why adults use it. We examined the prevalence of past-month marijuana use by users' reasons for use-medical, recreational, and both-and identified correlates...
Author(s): Kurtzman ET; Young-Wolff KC

Drug Alcohol Depend. 2021 Jun 29;226:108880. Epub 2021-06-29.

PubMed abstract

Participant education, spousal education and dementia risk in a diverse cohort of members of an integrated health care delivery system in Northern California

The role of spousal education on dementia risk and how it may differ by gender or race/ethnicity is unknown. This study examines the association between one's own education separate from and in conjunction with spousal education and risk of dementia. Coho...
Author(s): Gilsanz P; Mayeda ER; Eng CW; Meyer OL; Glymour MM; Quesenberry CP; Whitmer RA

BMJ Open. 2021 06 18;11(6):e040233. Epub 2021-06-18.

PubMed abstract

A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects

Cataract is the leading cause of blindness among the elderly worldwide and cataract surgery is one of the most common operations performed in the United States. As the genetic etiology of cataract formation remains unclear, we conducted a multiethnic geno...
Author(s): Choquet H; 23andMe Research Team; Jorgenson E; et al.

Nat Commun. 2021 06 14;12(1):3595. Epub 2021-06-14.

PubMed abstract

Attention-Deficit/Hyperactivity Disorder Medication Adherence in the Transition to Adulthood: Associated Adverse Outcomes for Females and Other Disparities

The purpose of this study was to assess the association between attention-deficit/hyperactivity disorder (ADHD) medication adherence and adverse health outcomes in older adolescents transitioning to adulthood. In a cohort of 17-year-old adolescents with A...
Author(s): Rao K; Carpenter DM; Campbell CI

J Adolesc Health. 2021 May 28.

PubMed abstract

Predicting adolescent alcohol and other drug problems using electronic health records data

Alcohol and other drug (AOD) use problems may cause significant burden on affected adolescents and their families, yet treatment providers often do not identify these problems early enough. To develop, and internally and externally validate a multivariabl...
Author(s): Chi FW; Alexeeff S; Ahmedani B; Boscarino JA; Waitzfelder B; Dugan R; Frankland T; Hu Y; Loree A; Sterling S

J Subst Abuse Treat. 2021 May 21;132:108487. Epub 2021-05-21.

PubMed abstract

Prospective validation of the Kaiser Permanente prostate cancer risk calculator in a contemporary, racially diverse, referral population

To prospectively validate a new prostate cancer risk calculator in a racially diverse population. We recently developed, internally validated and published the Kaiser Permanente Prostate Cancer Risk Calculator. This study is a prospective validation of th...
Author(s): Presti JC; Alexeeff S; Horton B; Prausnitz S; Avins AL

Urol Oncol. 2021 May 04.

PubMed abstract

Engaging patients in population-based chronic disease management: A qualitative study of barriers and intervention opportunities

Cardiovascular disease (CVD) continues to be a leading cause of morbidity in the U.S. Managing CVD risk factors, such as diabetes or hypertension, can be challenging for many individuals. We investigated the barriers experienced by patients who persistent...
Author(s): Fang A; Abdelgadir D; Gopalan A; Ross T; Uratsu CS; Sterling SA; Grant RW; Iturralde E

Patient Educ Couns. 2021 May 04.

PubMed abstract

PRimary Care Opioid Use Disorders treatment (PROUD) trial protocol: a pragmatic, cluster-randomized implementation trial in primary care for opioid use disorder treatment

Most people with opioid use disorder (OUD) never receive treatment. Medication treatment of OUD in primary care is recommended as an approach to increase access to care. The PRimary Care Opioid Use Disorders treatment (PROUD) trial tests whether implement...
Author(s): Campbell CI; Bradley KA; et al.

Addict Sci Clin Pract. 2021 Jan 31;16(1):9. Epub 2021-01-31.

PubMed abstract

Changes in Diagnostic and Demographic Characteristics of Patients Seeking Mental Health Care During the Early COVID-19 Pandemic in a Large, Community-Based Health Care System

The early COVID-19 pandemic resulted in great psychosocial disruption and stress, raising speculation that psychiatric disorders may worsen. This study aimed to identify patients vulnerable to worsening mental health during the COVID-19 pandemic. This ret...
Author(s): Ridout KK; Alavi M; Ridout SJ; Koshy MT; Harris B; Dhillon I; Awsare S; Weisner CM; Campbell CI; Iturralde E

J Clin Psychiatry. 2021 03 03;82(2). Epub 2021-03-03.

PubMed abstract

Association of Cannabis Retailer Proximity and Density With Cannabis Use Among Pregnant Women in Northern California After Legalization of Cannabis for Recreational Use

Author(s): Young-Wolff KC; Adams SR; Padon A; Silver LD; Alexeeff SE; Van Den Eeden SK; Avalos LA

JAMA Netw Open. 2021 Mar 01;4(3):e210694. Epub 2021-03-01.

PubMed abstract

Association of Pregnancy Intentions With Substance Use During Early Pregnancy

The goal of this study was to evaluate the association between pregnancy intentions and substance use in early pregnancy among pregnant women receiving prenatal care in a large, integrated healthcare system. The sample comprised 29,787 Kaiser Permanente N...
Author(s): Young-Wolff KC; Slama N; Sarovar V; Conway A; Tucker LY; Goler N; Terplan M; Ansley D; Adams SR; Armstrong MA

J Addict Med. 2021 Feb 16.

PubMed abstract

Cigarette smoking behaviors and the importance of ethnicity and genetic ancestry

Cigarette smoking contributes to numerous diseases and is one of the leading causes of death in the United States. Smoking behaviors vary widely across race/ethnicity, but it is not clear why. Here, we examine the contribution of genetic ancestry to varia...
Author(s): Choquet H; Yin J; Jorgenson E

Transl Psychiatry. 2021 Feb 11;11(1):120. Epub 2021-02-11.

PubMed abstract

Adverse Childhood Experiences and Early and Continued Breastfeeding: Findings from an Integrated Health Care Delivery System

Purpose: To examine whether adverse childhood experiences (ACEs) are associated with breastfeeding behaviors. Methods: Women in three Kaiser Permanente Northern California medical centers were screened for ACEs during standard prenatal care (N = 926). Mul...
Author(s): Watson C; Wei J; Varnado N; Rios N; Flanagan T; Alabaster A; Staunton M; Sterling SA; Gunderson E; Young-Wolff KC

J Womens Health (Larchmt). 2021 Feb 04.

PubMed abstract

Closing the gap: Identification and management of familial hypercholesterolemia in an integrated healthcare delivery system

Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder that causes markedly elevated risk for early onset coronary artery disease. Despite availability of effective therapy, only 5-10% of affected individuals worldwide are diagnosed....
Author(s): Birnbaum RA; Horton BH; Gidding SS; Brenman LM; Macapinlac BA; Avins AL

J Clin Lipidol. 2021 Feb 02.

PubMed abstract

Moving Toward Health and Social Equity for Women Who Use Cannabis During Preconception, Pregnancy, and Lactation

Author(s): Young-Wolff KC; Silver LD; Brown QL

JAMA Netw Open. 2021 Feb 01;4(2):e210148. Epub 2021-02-01.

PubMed abstract

Nicotine and cannabis vaping among adolescents in treatment for substance use disorders

This study examined nicotine and cannabis vaping among adolescents in treatment for substance use disorders. Participants were 363 adolescents aged 12-17 (66% male, mean age = 15.5 [SD = 1.3], 46% non-Hispanic white) seen for a specialty addiction intake ...
Author(s): Young-Wolff KC; Adams SR; Sterling SA; Tan ASL; Salloum RG; Torre K; Carter-Harris L; Prochaska JJ

J Subst Abuse Treat. 2021 06;125:108304. Epub 2021-01-27.

PubMed abstract

Three-Year Outcomes After Brief Treatment of Substance Use and Mood Symptoms

Screening, brief intervention, and referral to treatment (SBIRT) for adolescents exhibiting co-occurring substance use and mental health problems may improve outcomes and have long-lasting effects. This study examined the relationship between access to SB...
Author(s): Parthasarathy S; Kline-Simon AH; Jones A; Hartman L; Saba K; Weisner C; Sterling S

Pediatrics. 2021 Jan;147(1).

PubMed abstract

Treatment for Anxiety and Substance Use Disorders During the COVID-19 Pandemic: Challenges and Strategies

: The COVID-19 pandemic is likely to exacerbate existing anxiety and substance use disorders (SUDs) and increase vulnerability among individuals previously free of these conditions. Numerous pandemic-related stressors-coronavirus infection fears, social d...
Author(s): Satre DD; Iturralde E; Ghadiali M; Young-Wolff KC; Campbell CI; Leibowitz AS; Sterling SA

J Addict Med. 2020 12;14(6):e293-e296.

PubMed abstract

Health care utilization and HIV clinical outcomes among newly enrolled patients following Affordable Care Act implementation in a California integrated health system: a longitudinal study

The Affordable Care Act (ACA) has increased insurance coverage for people with HIV (PWH) in the United States. To inform health policy, it is useful to investigate how enrollment through ACA Exchanges, deductible levels, and demographic factors are associ...
Author(s): Satre DD; Parthasarathy S; Silverberg MJ; Horberg M; Young-Wolff KC; Williams EC; Volberding P; Campbell CI

BMC Health Serv Res. 2020 Nov 11;20(1):1030. Epub 2020-11-11.

PubMed abstract

Premature mortality associated with severe mental illness or substance use disorder in an integrated health care system

Research has reported shortened lifespans (by 15-30 years) for those with severe mental illness (SMI) or substance use disorder (SUD), particularly among public mental health treatment consumers. We assessed SMI- and SUD-associated mortality in the unders...
Author(s): Iturralde E; Slama N; Kline-Simon AH; Young-Wolff KC; Mordecai D; Sterling SA

Gen Hosp Psychiatry. 2020 Nov 10;68:1-6. Epub 2020-11-10.

PubMed abstract