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Behavioral Health and Aging Publications


Predictors of Healthcare Effectiveness Data and Information Set (HEDIS) treatment initiation and engagement among patients with opioid use disorder across 7 health systems

The prevalence of opioid use disorder (OUD) has increased rapidly in the United States and improving treatment access is critical. Among patients with OUD, we examined factors associated with the Healthcare Effectiveness Data and Information Set (HEDIS) p...
Author(s): Campbell CI; Weisner C; Binswanger IA; Lapham GT; Ahmedani BK; Yarborough BJH; Haller IV; Altschuler A; Hechter RC; Loree AM; Kline-Simon AH

Subst Abus. 2019 Jan 24:1-7.

PubMed abstract

Factors associated with Healthcare Effectiveness Data and Information Set (HEDIS) alcohol and other drug measure performance in 2014-2015

Only 10% of patients with alcohol and other drug (AOD) disorders receive treatment. The AOD Initiation and Engagement in Treatment (AOD-IET) measure was added to the national Healthcare Effectiveness Data and Information Set (HEDIS) to improve access to c...
Author(s): Weisner C; Campbell CI; Altschuler A; Sterling SA; Satre DD; Kline-Simon AH; et al.

Subst Abus. 2019 Jan 24:1-11.

PubMed abstract

Evaluation of a Pilot Perioperative Smoking Cessation Program: A Pre-Post Study

Surgical clinic and perioperative settings are critical touchpoints for treating smoking, yet health care systems have not typically prioritized smoking cessation among surgical patients. We evaluated the implementation of a pilot smoking cessation interv...
Author(s): Young-Wolff KC; Adams SR; Fogelberg R; Goldstein AA; Preston PG

J Surg Res. 2019 Jan 18;237:30-40. Epub 2019-01-18.

PubMed abstract

Genetic variation in the SIM1 locus is associated with erectile dysfunction

Erectile dysfunction affects millions of men worldwide. Twin studies support the role of genetic risk factors underlying erectile dysfunction, but no specific genetic variants have been identified. We conducted a large-scale genome-wide association study ...
Author(s): Jorgenson E; Yin J; Shan J; Hoffmann TJ; Thai KK; Van Den Eeden SK; et al.

Proc Natl Acad Sci USA. 2018 Oct 23;115(43):11018-11023. Epub 2018-10-08.

PubMed abstract

Characteristics of patients with substance use disorder before and after the Affordable Care Act

The Affordable Care Act (ACA) offered an unprecedented opportunity to expand insurance coverage to patients with substance use disorders (SUDs). We explored the expectations of key stakeholders for the ACA's impact on SUD care, and examined how clinical c...
Author(s): Campbell CI; Parthasarathy S; Altschuler A; Young-Wolff KC; Satre DD

Drug Alcohol Depend. 2018 Oct 06;193:124-130. Epub 2018-10-06.

PubMed abstract

Traumatic brain injury associated with dementia risk among people with type 1 diabetes

To examine the association between traumatic brain injury (TBI) and dementia risk among a cohort of middle-aged and elderly individuals with type 1 diabetes (T1D). We evaluated 4,049 members of an integrated health care system with T1D ≥50 years old betwe...
Author(s): Gilsanz P; Albers K; Beeri MS; Karter AJ; Quesenberry CP; Whitmer RA

Neurology. 2018 Sep 26.

PubMed abstract

Evaluating the Impact of Eliminating Copayments for Tobacco Cessation Pharmacotherapy

We examined the impact of the Affordable Care Act-mandated elimination of tobacco cessation pharmacotherapy (TCP) copayments on patient use of TCP, overall and by income. Electronic health record data captured any and combination (eg, nicotine gum plus pa...
Author(s): Young-Wolff KC; Adams SR; Klebaner D; Adams AS; Campbell CI; Satre DD; Prochaska JJ

Med Care. 2018 Sep 18.

PubMed abstract

Adverse Childhood Experiences and Mental and Behavioral Health Conditions During Pregnancy: The Role of Resilience

Little is known about how exposure to adverse childhood experiences (ACEs) and protective factors, such as resilience, influence prenatal mental and behavioral health. This study examined associations between exposure to ACEs and mental and behavioral hea...
Author(s): Young-Wolff KC; Alabaster A; McCaw B; Stoller N; Watson C; Sterling S; Ridout KK; Flanagan T

J Womens Health (Larchmt). 2018 Sep 05.

PubMed abstract

Data Are Needed on the Potential Adverse Effects of Marijuana Use in Pregnancy

The adverse effects of prenatal marijuana use remain unclear (1), yet more pregnant women are using marijuana in the United States than ever before (2, 3). Self-reported marijuana use during pregnancy increased from 2.4% in 2002 to 3.9% in 2014 (2), and 1...
Author(s): Goler N; Conway A; Young-Wolff KC

Ann Intern Med. 2018 Aug 21.

PubMed abstract

Association of Nausea and Vomiting in Pregnancy With Prenatal Marijuana Use

Use of marijuana, an antiemetic, is increasing among pregnant women,1,2 and data from 2 small surveys3,4 indicate that women self-report using marijuana to alleviate nausea and vomiting in pregnancy (NVP). To date, only 1 epidemiologic study5 has examined...
Author(s): Young-Wolff KC; Sarovar V; Tucker LY; Avalos LA; Conway A; Armstrong MA; Goler N

JAMA Intern Med. 2018 Aug 20.

PubMed abstract

A Large Multi-ethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci

Body mass index (BMI), a proxy measure for obesity, is determined by both environmental (including ethnicity, age, and sex) and genetic factors with over 400 BMI-associated loci identified to date. However, the impact, interplay, and underlying biological...
Author(s): Hoffmann TJ; Choquet H; Yin J; Banda Y; Kvale MN; Glymour M; Schaefer C; Risch N; Jorgenson E

Genetics. 2018 Aug 14.

PubMed abstract

Birth in High Infant Mortality States and Dementia Risk in a Cohort of Elderly African American and White Health Care Members

Birth in areas with high infant mortality rates (IMRs) has been linked to worse long-term health outcomes, yet it is completely unknown if it impacts dementia risk. In total 6268 health care members were followed for dementia diagnosis from 1996 to 2015. ...
Author(s): Gilsanz P; Mayeda ER; Glymour MM; Quesenberry CP; Mungas D; DeCarli CS; Whitmer RA

Alzheimer Dis Assoc Disord. 2018 Aug 13.

PubMed abstract

Association of behavioral health factors and social determinants of health with high and persistently high healthcare costs

A high proportion of U.S. health care costs are attributable to a relatively small proportion of patients. Understanding behavioral and social factors that predict initial and persistent high costs for these "high utilizers" is critical for heal...
Author(s): Sterling S; Chi F; Weisner C; Grant R; Pruzansky A; Bui S; Madvig P; Pearl R

Prev Med Rep. 2018 Sep;11:154-159. Epub 2018-06-27.

PubMed abstract

A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci

Primary open-angle glaucoma (POAG) is a leading cause of irreversible vision loss, yet much of the genetic risk remains unaccounted for, especially in African-Americans who have a higher risk for developing POAG. We conduct a multiethnic genome-wide assoc...
Author(s): Choquet H; Thai KK; Hoffmann TJ; Yin J; Schaefer C; Risch N; Jorgenson E; et al.

Nat Commun. 2018 Jun 11;9(1):2278. Epub 2018-06-11.

PubMed abstract

Changes in Psychiatric and Medical Conditions and Health Care Utilization Following a Diagnosis of Sexual Assault: A Retrospective Cohort Study

Sexual assault (SA) is alarmingly common and is associated with higher prevalence of psychiatric and medical conditions. However, many prior studies are limited to cross-sectional designs. Health care systems with electronic health records provide unique ...
Author(s): Young-Wolff KC; Sarovar V; Klebaner D; Chi F; McCaw B

Med Care. 2018 May 17.

PubMed abstract

Common mitochondrial haplogroups and cutaneous squamous cell carcinoma risk

Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer in America, and its incidence is substantially higher in men than women, but the reasons for the difference are unknown. We explored whether common mitochondrial DNA (mtDNA) haplogr...
Author(s): Jorgenson E; Choquet H; Yin J; Asgari M

Cancer Epidemiol Biomarkers Prev. 2018 Apr 25.

PubMed abstract

Depression in type 1 diabetes and risk of dementia

Depression afflicts 14% of individuals with type 1 diabetes (T1D). Depression is a robust risk factor for dementia but it is unknown if this holds true for individuals with T1D, who recently started living to an age conferring dementia risk. We examined i...
Author(s): Gilsanz P; Schnaider Beeri M; Karter AJ; Quesenberry CP; Adams AS; Whitmer RA

Aging Ment Health. 2018 Apr 10:1-7.

PubMed abstract

Factors associated with hazardous alcohol use and motivation to reduce drinking among HIV primary care patients: Baseline findings from the Health & Motivation study

Limited primary care-based research has examined hazardous drinking risk factors and motivation to reduce use in persons with HIV (PWH). We computed prevalence ratios (PR) for factors associated with recent (5) included: moderate/severe depression (PR...
Author(s): Silverberg MJ; Leibowitz A; Jang HJ; Sterling S; Parthasarathy S; Satre DD; et al.

Addict Behav. 2018 Mar 31;84:110-117. Epub 2018-03-31.

PubMed abstract

Patient and System Characteristics Associated with Performance on the HEDIS Measures of Alcohol and Other Drug Treatment Initiation and Engagement

Understand patient and system characteristics associated with performance on the Healthcare Effectiveness Data and Information Set (HEDIS) Alcohol and Other Drug (AOD) Initiation and Engagement of Treatment (IET) measures. This mixed-methods study linked ...
Author(s): Yarborough BJH; Chi FW; Green CA; Hinman A; Mertens J; Beck A; Horberg M; Weisner C; Campbell CI

J Addict Med. 2018 Mar 19.

PubMed abstract

Early Midlife Pulmonary Function and Dementia Risk

Poor pulmonary function (PPF) is associated with increased risk of dementia, yet it is unclear if PPF in early adulthood to midlife increases risk, independent of smoking and subsequent vascular disease. This study evaluated the association between multip...
Author(s): Gilsanz P; Mayeda ER; Flatt J; Glymour MM; Quesenberry CP; Whitmer RA

Alzheimer Dis Assoc Disord. 2018 Mar 14.

PubMed abstract

Use of a prescription opioid registry to examine opioid misuse and overdose in an integrated health system

Strategies are needed to identify at-risk patients for adverse events associated with prescription opioids. This study identified prescription opioid misuse in an integrated health system using electronic health record (EHR) data, and examined predictors ...
Author(s): Campbell CI; Bahorik AL; VanVeldhuisen P; Weisner C; Rubinstein AL; Ray GT

Prev Med. 2018 Feb 02;110:31-37. Epub 2018-02-02.

PubMed abstract

Pediatrician and Behavioral Clinician-Delivered Screening, Brief Intervention and Referral to Treatment: Substance Use and Depression Outcomes

Early intervention for adolescent substance use and mental health problems may mitigate potential harm. We examined patient outcomes from a pragmatic trial of two modalities of delivering screening, brief intervention, and referral to treatment (SBIRT) an...
Author(s): Sterling S; Kline-Simon AH; Weisner C; Jones A; Satre DD

J Adolesc Health. 2018 Jan 23.

PubMed abstract

Feasibility and Acceptability of Screening for Adverse Childhood Experiences in Prenatal Care

Adverse childhood experiences (ACEs) are common among pregnant women and contribute to increased risk for negative perinatal outcomes, yet few clinicians screen prenatal patients for ACEs. The purpose of this study was to evaluate the feasibility and acce...
Author(s): Flanagan T; Alabaster A; McCaw B; Stoller N; Watson C; Young-Wolff KC

J Womens Health (Larchmt). 2018 Jan 19.

PubMed abstract

Documentation of e-cigarette use and associations with smoking from 2012 to 2015 in an integrated healthcare delivery system

It is unclear whether use of electronic nicotine delivery systems (ENDS) precedes cigarette smoking initiation, relapse, and/or quitting. Healthcare systems with electronic health records (EHRs) provide unique data to examine ENDS use and changes in smoki...
Author(s): Young-Wolff KC; Klebaner D; Folck B; Tan ASL; Fogelberg R; Sarovar V; Prochaska JJ

Prev Med. 2018 Jan 19.

PubMed abstract

Trends in Self-reported and Biochemically Tested Marijuana Use Among Pregnant Females in California From 2009-2016

Author(s): Young-Wolff KC; Tucker LY; Alexeeff S; Armstrong MA; Conway A; Weisner C; Goler N

JAMA. 2017 12 26;318(24):2490-2491.

PubMed abstract