This study examines 1) whether cigarette smoking and nicotine vaping are associated with elevated risk for onset of COVID-19 infection and worse disease severity, and 2) whether risks associated with cigarette smoking and nicotine vaping are greater among...
Funder: Tobacco-Related Disease Research Program
Investigator: Young-Wolff, Kelly
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This prospective observational study including 1,500 KPNC adult members with treatment-resistant depression will characterize factors related to selection of electroconvulsive therapy, transcranial magnetic stimulation, or ketamine; examine success rates ...
Funder: TPMG Delivery Science Projects Program
Investigator: Iturralde, Estibaliz
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Cataract is a leading cause of blindness and a major cause of impaired vision worldwide. The overall objective of this study is to better understand the role of genetic and non-genetic factors and causal mechanisms underlying the etiology of cataract and ...
Funder: National Eye Institute
Investigator: Choquet, Helene
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The Life After 90 Study (LA90) is a collaborative study between DOR, UC Davis, and UC Irvine following a diverse cohort of approximately 1,000 KPNC members age 90 and over to examine life course risk factors of cognitive decline and dementia risk. This st...
Funder: National Institute on Aging
Investigator: Gilsanz, Paola
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Qualitative data are critically needed to better understand knowledge gaps, preferences, and social and cultural factors that differentially contribute to prenatal cannabis use among Black and White women. To address these important gaps in knowledge, we ...
Funder: Kaiser Permanente Division of Research
Investigator: Young-Wolff, Kelly
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Recreational cannabis legalization (RCL) has high potential to lead to increases in adolescent cannabis use and related health conditions, but few studies have examined this question and results are mixed. Using data from adolescents in KPNC''s large inte...
Funder: National Institute on Drug Abuse
Investigator: Young-Wolff, Kelly
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This K23 career development project seeks to leverage electronic health record data from KPNC and 2 health system collaborators within the Mental Health Research Network to investigate population health management strategies to prevent diabetes and improv...
Funder: National Institute of Mental Health
Investigator: Iturralde, Estibaliz
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The Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE) Study, a collaborative study between DOR and UC Davis, follows a diverse cohort of Kaiser Permanente Northern California members who participated in at least one optional check-up (Multiphasi...
Funder: National Institute on Aging
Investigator: Gilsanz, Paola
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Bariatric surgery is currently the most effective long-term treatment for severe obesity. However, inter-individual variability in surgery outcomes has been observed, particularly in relation to postoperative weight loss. This study aims to assess the con...
Funder: Northern California Community Benefit Programs
Investigator: Choquet, Helene
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This study will increase our understanding of the development of alcohol use disorders (AUD) and recovery from AUD, including factors that affect the likelihood of recovery success, such as quantity of alcohol consumed and the involvement of health and su...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Weisner, Constance
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This program, funded by a National Institute of Mental Health Institutional Research Training Grant (T32), has 2
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The registry will increase understanding of the development of alcohol use disorders (AUD) and recovery from AUD, including factors that affect the likelihood of recovery success, such as quantity of alcohol consumed and the involvement of health and subs...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Weisner, Constance
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This study aims to use population management to improve the quality and overall health outcomes of people with schizophrenia, schizoaffective disorder, and bipolar disorder.
Funder: TPMG Delivery Science Projects Program
Investigator: Iturralde, Estibaliz
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This study examines associations between different degrees of adherence to components of the Family Based Therapy model of care for adolescent eating disorders and clinical quality outcomes among the outpatient programs in medical centers across Kaiser Pe...
Funder: TPMG Delivery Science Projects Program
Investigator: Sterling, Stacy
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This study, being done with a parallel effort at UCSF, will focus on how bipolar disease is related to Parkinson's disease. We will look within the KPNC membership data, as well as focusing on a specific KP study population of bipolar disease.
Funder: Michael J. Fox Foundation
Investigator: Schaefer, Catherine; Van Den Eeden, Stephen
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Large observational study to evaluate the effects of initiating buprenorphine treatment on subsequent suicidal behavior among people with opioid use disorder.
Funder: National Institute of Mental Health
Investigator: Campbell, Cynthia
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Hidradenitis suppurativa (also named: acne inversa) is a chronic inflammatory skin condition that causes painful lumps to form under the skin usually in areas where skin rubs together such as in the armpits, groin, buttocks and under breasts. The overall ...
Funder: National Institute of Arthritis and Musculoskeletal and Skin Diseases
Investigator: Choquet, Helene
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This study examines the increase in alcohol consumption during the Covid-19 pandemic and the major shift to virtual treatment modalities for alcohol problems, with a focus on potential disparities in treatment access, by race, ethnicity, age and gender. U...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Sterling, Stacy
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This study will examine substance use treatment among patients with hepatitis C who have unhealthy alcohol use and how well they engage in appropriate and timely hepatitis C care. The findings will be used to conduct an intervention study aimed at improvi...
Funder: Northern California Community Benefit Programs
Investigator: Campbell, Cynthia
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The study will assess the effects of statin treatment on risk of Alzheimer's disease and related dementias, controlling for potential confounding and examining potential mediating factors among Kaiser Permanente Northern California members during the year...
Funder: National Institute on Aging
Investigator: Schaefer, Catherine
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A cluster-randomized trial of Addiction Medicine consultation (AMC) for primary care physicians (PCPs) and patients examining the effectiveness of a telehealth AMC intervention on initiation of alcohol use treatment, anti-craving medication and/or special...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Sterling, Stacy
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As of March 26, 2020, there have been more than 80,000 cases and 1,000 deaths in the US due to COVID-19. Because it attacks the lungs, COVID-19 could be an especially serious threat to those who smoke or vape tobacco or cannabis. This study will use data ...
Funder: National Institute on Drug Abuse
Investigator: Young-Wolff, Kelly; Avalos, Lyndsay
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This pilot study will use data from Kaiser Permanente Northern California electronic health records to examine whether current and former smokers are at elevated risk for COVID-19 infection and disease severity relative to never smokers. We will also look...
Funder: Tobacco-Related Disease Research Program
Investigator: Young-Wolff, Kelly
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This study will investigate whether maternal prenatal marijuana use increases the risk of impairments in a child's executive functioning and mental health, after accounting for other factors such as tobacco, alcohol, and other drug use; socioeconomic stat...
Funder: National Institute on Drug Abuse
Investigator: Avalos, Lyndsay; Young-Wolff, Kelly
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About 25% of people over the age of 65 are living with diabetes, with 90% of them managing type 2 diabetes. Studies have shown that older individuals with type 2 diabetes have a 51-62% higher risk of dementia than those without type 2 diabetes. This study...
Funder:
Investigator: Gilsanz, Paola
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