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Behavioral Health and Aging Studies

 

Embedded Mental Health Services Postdoctoral Research Training in Health Systems

This program, funded by a National Institute of Mental Health Institutional Research Training Grant (T32), has 2

Kaiser Permanente Northern California Alcohol Registry

The registry will increase understanding of the development of alcohol use disorders (AUD) and recovery from AUD, including factors that affect the likelihood of recovery success, such as quantity of alcohol consumed and the involvement of health and subs...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Weisner, Constance

Improve Quality and Overall Health Outcomes Through Population Management to Treat Schizophrenia, Schizoaffective Disorder and Bipolar Disorder

This study aims to use population management to improve the quality and overall health outcomes of people with schizophrenia, schizoaffective disorder, and bipolar disorder.
Funder: TPMG Delivery Science Projects Program
Investigator: Iturralde, Estibaliz

Identifying Best Practices of Early Phase Pediatric Eating Disorder Care

This study examines associations between different degrees of adherence to components of the Family Based Therapy model of care for adolescent eating disorders and clinical quality outcomes among the outpatient programs in medical centers across Kaiser Pe...
Funder: TPMG Delivery Science Projects Program
Investigator: Sterling, Stacy

Bipolar Disease and Parkinson's Disease

This study, being done with a parallel effort at UCSF, will focus on how bipolar disease is related to Parkinson's disease. We will look within the KPNC membership data, as well as focusing on a specific KP study population of bipolar disease.
Funder: Michael J. Fox Foundation
Investigator: Schaefer, Catherine; Van Den Eeden, Stephen

Buprenorphine Effect on Suicidal Behavior

Large observational study to evaluate the effects of initiating buprenorphine treatment on subsequent suicidal behavior among people with opioid use disorder.
Funder: National Institute of Mental Health
Investigator: Campbell, Cynthia

Identification of genetic loci and pathways underlying hidradenitis suppurativa risk

Hidradenitis suppurativa (also named: acne inversa) is a chronic inflammatory skin condition that causes painful lumps to form under the skin usually in areas where skin rubs together such as in the armpits, groin, buttocks and under breasts. The overall ...
Funder: National Institute of Arthritis and Musculoskeletal and Skin Diseases
Investigator: Choquet, Helene

Implementation of Alcohol Screening and Brief Intervention in a Health System: Sustainability, Fidelity and Patient Outcomes, Covid-19 Supplement

This study examines the increase in alcohol consumption during the Covid-19 pandemic and the major shift to virtual treatment modalities for alcohol problems, with a focus on potential disparities in treatment access, by race, ethnicity, age and gender. U...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Sterling, Stacy

Alcohol-Related Care and HCV Treatment among Patients with Problematic Alcohol Use and HCV

This study will examine substance use treatment among patients with hepatitis C who have unhealthy alcohol use and how well they engage in appropriate and timely hepatitis C care. The findings will be used to conduct an intervention study aimed at improvi...
Funder: Northern California Community Benefit Programs
Investigator: Campbell, Cynthia

Statin Treatment and Incident Alzheimer’s Disease and Related Dementias in a Large, Multi-ethnic Health Plan

The study will assess the effects of statin treatment on risk of Alzheimer's disease and related dementias, controlling for potential confounding and examining potential mediating factors among Kaiser Permanente Northern California members during the year...
Funder: National Institute on Aging
Investigator: Schaefer, Catherine

Addiction Telemedicine Consultation in Primary Care: Increasing Access to Pharmacotherapy and Specialty Treatment for Alcohol Problems

A cluster-randomized trial of Addiction Medicine consultation (AMC) for primary care physicians (PCPs) and patients examining the effectiveness of a telehealth AMC intervention on initiation of alcohol use treatment, anti-craving medication and/or special...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Sterling, Stacy

Maternal Marijuana Use During Pregnancy, Marijuana Legalization, and Adverse Obstetrical and Neonatal Outcomes: A 12-year Cohort Study (COVID-19 Revision)

As of March 26, 2020, there have been more than 80,000 cases and 1,000 deaths in the US due to COVID-19. Because it attacks the lungs, COVID-19 could be an especially serious threat to those who smoke or vape tobacco or cannabis. This study will use data ...
Funder: National Institute on Drug Abuse
Investigator: Young-Wolff, Kelly; Avalos, Lyndsay

Smoking as a Risk Factor for COVID-19 Onset and Severity

This pilot study will use data from Kaiser Permanente Northern California electronic health records to examine whether current and former smokers are at elevated risk for COVID-19 infection and disease severity relative to never smokers. We will also look...
Funder: Tobacco-Related Disease Research Program
Investigator: Young-Wolff, Kelly

Impact of In Utero Marijuana Exposure on Neurodevelopment, Behavior and Mental Health: A Longitudinal Birth Cohort Study

This study will investigate whether maternal prenatal marijuana use increases the risk of impairments in a child's executive functioning and mental health, after accounting for other factors such as tobacco, alcohol, and other drug use; socioeconomic stat...
Funder: National Institute on Drug Abuse
Investigator: Avalos, Lyndsay; Young-Wolff, Kelly

Glycemic Control and Dementia: The Role of Pharmacotherapy and Vascular Complications

About 25% of people over the age of 65 are living with diabetes, with 90% of them managing type 2 diabetes. Studies have shown that older individuals with type 2 diabetes have a 51-62% higher risk of dementia than those without type 2 diabetes. This study...
Funder: 
Investigator: Gilsanz, Paola

The Role of Genetic Risk Factors in Keratinocyte Carcinoma Susceptibility

The goal of this proposal is to identify genetic loci that affect the risk of keratinocyte carcinoma, examine how environmental risk factors influence genetic risk, and determine whether these loci act to influence the risk of basal cell carcinoma, squamo...
Funder: National Cancer Institute
Investigator: Choquet, Helene; Asgari, Maryam

Mental Health Research Network III

The Mental Health Research Network (MHRN) is a consortium of 13 health system research centers, embedded in large and diverse healthcare systems, dedicated to improving patient mental health through research, practice, and policy; with expertise in mental...
Funder: National Institute of Mental Health
Investigator: Sterling, Stacy

Genetics at an Extreme: An Efficient Genomic Study of Individuals with Clinically Severe Major Depression Receiving ECT

This study brings together investigators from around the world to carry out a genetics study of severe major depressive disorder (MDD) treated with electroconvulsive therapy (ECT). The National Network of Depression Centers and allied centers in t...
Funder: National Institute of Mental Health
Investigator: Schaefer, Catherine

Pragmatic Trial of Acupuncture for Chronic Low Back Pain in Older Adults

The goal of this project is to conduct a three-arm parallel-group randomized clinical trial of two acupuncture interventions vs. a usual-care control group for change in low back pain symptoms among adults at least 65 years of age.
Funder: National Center for Complementary and Integrative Health
Investigator: Avins, Andrew

Contributions of Educational Quality and Occupational Complexity on Racial and Ethnic Inequities in Brain Health and Alzheimer's Disease and Related Dementia

This study utilizes a lifecourse approach to evaluate the roles of education quality and occupational complexity on dementia risk and cognitive decline and to examine if patterns of educational quality and occupational complexity across the lifecourse dri...
Funder: National Institute on Aging
Investigator: Gilsanz, Paola

Effects of Medical Products on Suicidal Ideation and Behavior: Real World Evidence

This study will provide a comprehensive program of infrastructure development, methods development, and innovative research to generate real-world evidence addressing critical gaps in the regulation of medical products. We will explore four related issues...
Funder: U.S. Food and Drug Administration
Investigator: Sterling, Stacy

A Randomized, Double-Blind, Noninferiority Trial of Adductor Canal Catheters for Postoperative Pain Management among Patients Undergoing Elective Unilateral Total Knee Arthroplasty

A randomized, double-blind noninferiority trial of adductor canal catheters for postoperative pain management among patients undergoing elective, unilateral, total-knee arthroplasty.
Funder: The Permanente Medical Group
Investigator: Avins, Andrew

Expanding the Scope and Reach of Adolescent Substance Use Early Intervention Research

This study explores the enduring impact of screening, brief intervention, and referral to treatment (SBIRT) delivered in pediatric primary care, on young adults. We will examine substance use, mental health and medical outcomes, and health services utiliz...
Funder: Conrad N. Hilton Foundation
Investigator: Sterling, Stacy

Implementation of Alcohol Screening and Brief Intervention in a Health System: Sustainability, Fidelity, and Patient Outcomes

Using a theory-driven conceptual framework, this multimethod study examines factors that facilitate or impede the successful implementation and long-term sustainability of screening, brief intervention, and referral to treatment (SBIRT) for risky alcohol ...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Sterling, Stacy

Maternal Marijuana Use During Pregnancy, Marijuana Legalization, and Adverse Obstetrical and Neonatal Outcomes: A 12-year Cohort Study

The goal of this application is to examine the association between maternal marijuana use during pregnancy and adverse obstetrical and neonatal outcomes. We aim to: 1) Examine trends in prenatal marijuana use following the legalization of marijuana for re...
Funder: National Institute on Drug Abuse
Investigator: Avalos, Lyndsay; Young-Wolff, Kelly
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