The
goal of this proje...
Funder: National Center for Complementary and Integrative Health
Investigator: Avins, Andrew
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This study utilizes a lifecourse approach to evaluate the roles of education quality and occupational complexity on dementia risk and cognitive decline and to examine if patterns of educational quality and occupational complexity across the lifecourse dri...
Funder: National Institute on Aging
Investigator: Gilsanz, Paola
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This study will provide a comprehensive program of infrastructure development, methods development, and innovative research to generate real-world evidence addressing critical gaps in the regulation of medical products. We will explore four related issues...
Funder: U.S. Food and Drug Administration
Investigator: Sterling, Stacy
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A randomized, double-blind noninferiority trial of adductor canal catheters for postoperative pain management among patients undergoing elective, unilateral, total-knee arthroplasty.
Funder: The Permanente Medical Group
Investigator: Avins, Andrew
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This study explores the enduring impact of screening, brief intervention, and referral to treatment (SBIRT) delivered in pediatric primary care, on young adults. We will examine substance use, mental health and medical outcomes, and health services utiliz...
Funder: Conrad N. Hilton Foundation
Investigator: Sterling, Stacy
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Using a theory-driven conceptual framework, this multimethod study examines factors that facilitate or impede the successful implementation and long-term sustainability of screening, brief intervention, and referral to treatment (SBIRT) for risky alcohol ...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Sterling, Stacy
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The goal of this application is to examine the association between maternal marijuana use during pregnancy and adverse obstetrical and neonatal outcomes. We aim to: 1) Examine trends in prenatal marijuana use following the legalization of marijuana fo...
Funder: National Institute on Drug Abuse
Investigator: Avalos, Lyndsay; Young-Wolff, Kelly
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The goal of this project is 1) to collect longitudinal measures of cognitive function, quality of life, and physical disability on a multi-ethnic sample of 3,000 individuals with multiple sclerosis (MS), using a web-based interface, Clinical and Longitudi...
Funder: National Institute of Nursing Research
Investigator: Schaefer, Catherine
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The goal of this project is to investigate the effects of genetic polymorphisms in the KIR and HLA genes on psoriasis and psoriatic arthritis.
Funder: University of California, Los Angeles
Investigator: Jorgenson, Eric
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Henry Ford Health System, Kaiser Permanente Colorado, Kaiser Permanente Northern California, Kaiser Permanente Northwest, and Kaiser Permanente Southern California are implementing the National Zero Suicide Model (NZSM), and have received funding from the...
Funder: National Institute of Mental Health
Investigator: Sterling, Stacy
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This study involves a partnership between Kaiser Permanente Northern California, Kaiser Permanente Colorado, Henry Ford Health System, and the University of Washington Social Development Research Group. The collaborators will conduct a pragmatic trial tes...
Funder: National Center for Complementary and Integrative Health
Investigator: Sterling, Stacy
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The goal of this Food and Drug Administration-mandated study is to provide quantitative estimates of the serious risks of misuse, abuse, addiction, overdose, and death associated with long-term use of opioid analgesics for management of chronic pain, ...
Funder: Syneos Health
Investigator: Campbell, Cynthia
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Building on past research, this project will establish the infrastructure to expand a prescription opioid registry across diverse health systems in the Addiction Research Network. Harmonized electronic health record data elements will be used to exami...
Funder: National Institute on Drug Abuse
Investigator: Campbell, Cynthia
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The goal of this project is to address the following research question: Does the use of antidepressant treatment, specifically, selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), reduce th...
Funder: Northern California Community Benefit Programs
Investigator: Jorgenson, Eric
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The objective of this project is to investigate the genetic mechanisms that drive the development of abdominal hernias. This study has three major aims: 1) to investigate the shared and individual genetic risks of different types of abdominal hern...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Choquet, Helene; Jorgenson, Eric
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Funder: The Permanente Medical Group
Investigator: Campbell, Cynthia
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The International Bipolar Sequencing Consortium brings together whole-genome and exome sequence data from multiple case-control and family studies of bipolar disorder for the purpose of investigating the genetic architecture of this condition. Data from m...
Funder: National Institute of Mental Health
Investigator: Schaefer, Catherine
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This study will evaluate a quality improvement pilot project being conducted at pediatrics departments in the greater Kaiser Permanente Southern Alameda County area. The pilot project involves screening children at 1-to-5-year-old well child visits for ad...
Funder: The Permanente Medical Group
Investigator: Sterling, Stacy
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The major goal of this project is to maintain and expand the San Francisco Mammography Registry and to evaluate the performance of mammography in an ethnically diverse population.
Funder: National Cancer Institute
Investigator: Avins, Andrew
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This study seeks to develop metrics for evaluation of the Zero Suicide model across five integrated health care systems. These metrics will be used to investigate model fidelity and suicide behavior outcomes across sites. More specifically, this project a...
Funder: National Institute of Mental Health
Investigator: Sterling, Stacy
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In June 2013, Kaiser Permanente Northern California incorporated alcohol screening, brief intervention, and referral to treatment (SBIRT) into the clinical workflow of its Adult Medicine program, alongside other preventive health measures (e.g., smoking s...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Sterling, Stacy
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This study will survey a sample of patients with pain about their use of medical marijuana. The goal is to describe patterns of use, mode, medical conditions, or symptoms for which medical marijuana is used, as well as perceived benefits, side effects, an...
Funder: Northern California Community Benefit Programs
Investigator: Campbell, Cynthia
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The specific aims of this study are to: 1) Determine whether refractive error predicts the development of glaucoma due to direct effects or shared etiology, or both, by conducting a series of genetic analyses of the two conditions; and 2) Determine th...
Funder: National Eye Institute
Investigator: Choquet, Helene; Jorgenson, Eric
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