The study will assess the effects of statin treatment on risk of Alzheimer's disease and related dementias, controlling for potential confounding and examining potential mediating factors among Kaiser Permanente Northern California members during the year...
Funder: National Institute on Aging
Investigator: Schaefer, Catherine
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A cluster-randomized trial of Addiction Medicine consultation (AMC) for primary care physicians (PCPs) and patients examining the effectiveness of a telehealth AMC intervention on initiation of alcohol use treatment, anti-craving medication and/or special...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Sterling, Stacy
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As of March 26, 2020, there have been more than 80,000 cases and 1,000 deaths in the US due to COVID-19. Because it attacks the lungs, COVID-19 could be an especially serious threat to those who smoke or vape tobacco or cannabis. This study will use data ...
Funder: National Institute on Drug Abuse
Investigator: Young-Wolff, Kelly; Avalos, Lyndsay
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This pilot study will use data from Kaiser Permanente Northern California electronic health records to examine whether current and former smokers are at elevated risk for COVID-19 infection and disease severity relative to never smokers. We will also look...
Funder: Tobacco-Related Disease Research Program
Investigator: Young-Wolff, Kelly
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About 25% of people over the age of 65 are living with diabetes, with 90% of them managing type 2 diabetes. Studies have shown that older individuals with type 2 diabetes have a 51-62% higher risk of dementia than those without type 2 diabetes. This study...
Funder:
Investigator: Gilsanz, Paola
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The Mental Health Research Network (MHRN) is a consortium of 13 health system research centers, embedded in large and diverse healthcare systems, dedicated to improving patient mental health through research, practice, and policy; with expertise in mental...
Funder: National Institute of Mental Health
Investigator: Sterling, Stacy
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This
study brings together investigators from around the world to carry out a
genetics study of severe major depressive disorder (MDD) treated with
electroconvulsive therapy (ECT). The National Network of Depression Centers
and allied centers in t...
Funder: National Institute of Mental Health
Investigator: Schaefer, Catherine
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The
goal of this project is to conduct a three-arm parallel-group randomized
clinical trial of two acupuncture interventions vs. a usual-care control
group for change in low back pain symptoms among adults at least 65 years of
age.
Funder: National Center for Complementary and Integrative Health
Investigator: Avins, Andrew
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This study utilizes a lifecourse approach to evaluate the roles of education quality and occupational complexity on dementia risk and cognitive decline and to examine if patterns of educational quality and occupational complexity across the lifecourse dri...
Funder: National Institute on Aging
Investigator: Gilsanz, Paola
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This study will provide a comprehensive program of infrastructure development, methods development, and innovative research to generate real-world evidence addressing critical gaps in the regulation of medical products. We will explore four related issues...
Funder: U.S. Food and Drug Administration
Investigator: Sterling, Stacy
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A randomized, double-blind noninferiority trial of adductor canal catheters for postoperative pain management among patients undergoing elective, unilateral, total-knee arthroplasty.
Funder: The Permanente Medical Group
Investigator: Avins, Andrew
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This study explores the enduring impact of screening, brief intervention, and referral to treatment (SBIRT) delivered in pediatric primary care, on young adults. We will examine substance use, mental health and medical outcomes, and health services utiliz...
Funder: Conrad N. Hilton Foundation
Investigator: Sterling, Stacy
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Using a theory-driven conceptual framework, this multimethod study examines factors that facilitate or impede the successful implementation and long-term sustainability of screening, brief intervention, and referral to treatment (SBIRT) for risky alcohol ...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Sterling, Stacy
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The goal of this application is to examine the association between maternal marijuana use during pregnancy and adverse obstetrical and neonatal outcomes. We aim to: 1) Examine trends in prenatal marijuana use following the legalization of marijuana for re...
Funder: National Institute on Drug Abuse
Investigator: Avalos, Lyndsay; Young-Wolff, Kelly
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The goal of this project is 1) to collect longitudinal measures of cognitive function, quality of life, and physical disability on a multi-ethnic sample of 3,000 individuals with multiple sclerosis (MS), using a web-based interface, Clinical and Longitudi...
Funder: National Institute of Nursing Research
Investigator: Schaefer, Catherine
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Henry Ford Health System, Kaiser Permanente Colorado, Kaiser Permanente Northern California, Kaiser Permanente Northwest, and Kaiser Permanente Southern California are implementing the National Zero Suicide Model (NZSM), and have received funding from the...
Funder: National Institute of Mental Health
Investigator: Sterling, Stacy
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This study involves a partnership between Kaiser Permanente Northern California, Kaiser Permanente Colorado, Henry Ford Health System, and the University of Washington Social Development Research Group. The collaborators will conduct a pragmatic trial tes...
Funder: National Center for Complementary and Integrative Health
Investigator: Sterling, Stacy
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The goal of this Food and Drug Administration-mandated study is to provide quantitative estimates of the serious risks of misuse, abuse, addiction, overdose, and death associated with long-term use of opioid analgesics for management of chronic pain, amo...
Funder: Syneos Health
Investigator: Campbell, Cynthia
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Building on past research, this project will establish the infrastructure to expand a prescription opioid registry across diverse health systems in the Addiction Research Network. Harmonized electronic health record data elements will be used to examine ...
Funder: National Institute on Drug Abuse
Investigator: Campbell, Cynthia
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Funder: The Permanente Medical Group
Investigator: Campbell, Cynthia
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The International Bipolar Sequencing Consortium brings together whole-genome and exome sequence data from multiple case-control and family studies of bipolar disorder for the purpose of investigating the genetic architecture of this condition. Data from m...
Funder: National Institute of Mental Health
Investigator: Schaefer, Catherine
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This study will evaluate a quality improvement pilot project being conducted at pediatrics departments in the greater Kaiser Permanente Southern Alameda County area. The pilot project involves screening children at 1-to-5-year-old well child visits for ad...
Funder: The Permanente Medical Group
Investigator: Sterling, Stacy
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The major goal of this project is to maintain and expand the San Francisco Mammography Registry and to evaluate the performance of mammography in an ethnically diverse population.
Funder: National Cancer Institute
Investigator: Avins, Andrew
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This study seeks to develop metrics for evaluation of the Zero Suicide model across five integrated health care systems. These metrics will be used to investigate model fidelity and suicide behavior outcomes across sites. More specifically, this project a...
Funder: National Institute of Mental Health
Investigator: Sterling, Stacy
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In June 2013, Kaiser Permanente Northern California incorporated alcohol screening, brief intervention, and referral to treatment (SBIRT) into the clinical workflow of its Adult Medicine program, alongside other preventive health measures (e.g., smoking s...
Funder: National Institute on Alcohol Abuse and Alcoholism
Investigator: Sterling, Stacy
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