Paradigm-Shifting Research in Gastroenterology, Hepatology, and Nutrition: A Top 20 List of Articles Published in 2020
Author(s): Corley DA; Peek RM; Simpson BA
Gastroenterology. 2021 Jan 14.
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Disparities in Preventable Mortality from Colorectal Cancer: are they the result of structural racism?
Author(s): Doubeni CA; Selby K; Levin TR
Gastroenterology. 2021 Jan 05.
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When Should We Let Colorectal Cancer Screening Get Personal?
Although screening reduces colorectal cancer (CRC) incidence and related mortality, national CRC screening rates remain suboptimal. Identifying strategies to improve screening rates remains an area of intense focus, and previous literature supports an ass...
Author(s): Lam AY; Lee JK
Am J Gastroenterol. 2020 Dec 09.
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Recruitment strategies and design considerations in a trial of resistance training to prevent dose-limiting toxicities in colon cancer patients undergoing chemotherapy
Low muscle is associated with an increased risk of chemotherapy-related dose limiting toxicities (DLT) in cancer patients. Resistance training (RT) improves muscle mass; however, the effects of RT on preventing DLTs and dose reductions in colon cancer pat...
Author(s): Caan BJ; Meyerhardt JA; Brown JC; Campbell KL; Cespedes Feliciano EM; Lee C; Ross MC; Quinney S; Quesenberry C; Sternfeld B; Schmitz KH
Contemp Clin Trials. 2020 Dec 07;101:106242. Epub 2020-12-07.
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A Mobile Health Mindfulness Intervention for Women With Moderate to Moderately Severe Postpartum Depressive Symptoms: Feasibility Study
Approximately 20% of women suffer from postpartum depression (PPD). Due to barriers such as limited access to care, half of the women with PPD do not receive treatment. Therefore, it is critical to identify effective and scalable interventions. Traditiona...
Author(s): Avalos LA; Aghaee S; Kurtovich E; Quesenberry C; Nkemere L; McGinnis MK; Kubo A
JMIR Ment Health. 2020 Nov 12;7(11):e17405. Epub 2020-11-12.
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Editors in Chief, Gastroenterology
Author(s): Peek RM; Corley DA
Gastroenterology. 2020 Dec 29.
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Early life household intactness and timing of pubertal onset in girls: a prospective cohort study
Girls who experience early-life familial stress may have heightened risk of early puberty, which has adverse implications for adolescent and adult health. We assessed the association between household intactness and pubertal onset using a racially/ethnica...
Author(s): Aghaee S; Deardorff J; Greenspan LC; Quesenberry CP; Kushi LH; Kubo A
BMC Pediatr. 2020 Oct 28;20(1):464. Epub 2020-10-28.
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Cancer Screening during COVID-19: A Perspective from NCI's PROSPR consortium
Author(s): Corley DA; Sedki M; Haas JS; et al.
Gastroenterology. 2020 Oct 21.
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Influence of Telemedicine-First Intervention on Patient Visit Choice, Post-Visit Care, and Patient Satisfaction in Gastroenterology
Author(s): Munroe CA; Lin TY; Rouillard S; Fox J; Lee JK; Corley DA
Gastroenterology. 2020 Oct 16.
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Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk
Mammographic density (MD) phenotypes are strongly associated with breast cancer risk and highly heritable. In this GWAS meta-analysis of 24,192 women, we identify 31 MD loci at P < 5 × 10-8, tripling the number known to 46. Seventeen identified MD loci al...
Author(s): Sieh W; Alexeeff SE; Sakoda LC; Jorgenson E; Schaefer C; Habel LA; et al.
Nat Commun. 2020 10 09;11(1):5116. Epub 2020-10-09.
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Pilot pragmatic randomized trial of mHealth mindfulness-based intervention for advanced cancer patients and their informal caregivers
Assess the feasibility of conducting a cluster randomized trial (RCT) comparing technology-delivered mindfulness-based intervention (MBI) programs against a waitlist control arm targeting advanced cancer patients and their informal caregivers. Two-arm clu...
Author(s): Kubo A; Kurtovich E; McGinnis M; Aghaee S; Altschuler A; Quesenberry C; Kolevska T; Liu R; Greyz-Yusupov N; Avins A
Psychooncology. 2020 Sep 26.
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Association of Prediagnostic Frailty, Change in Frailty Status, and Mortality After Cancer Diagnosis in the Women's Health Initiative
Understanding changes in frailty in relation to cancer diagnosis can inform optimal selection of cancer treatments and survivorship care. To investigate associations of prediagnostic frailty and change in frailty status with mortality after a cancer diagn...
Author(s): Cespedes Feliciano EM; Hohensee C; Rosko AE; Anderson GL; Paskett ED; Zaslavsky O; Wallace RB; Caan BJ
JAMA Netw Open. 2020 Sep 01;3(9):e2016747. Epub 2020-09-01.
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Streamlining genetic testing for women with ovarian cancer in a Northern California health care system
Referral to Genetics for pre-testing counseling may be inefficient for women with ovarian cancer. This study assesses feasibility of gynecologic oncologists directly offering genetic testing. A prospective pilot study was conducted at two gynecologic onco...
Author(s): Powell CB; Lee J; Kushi LH; et al.
Gynecol Oncol. 2020 Aug 07.
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Early Screening of African Americans (45-50 Years Old) in a Fecal Immunochemical Test-based Colorectal Cancer Screening Program
Some guidelines recommend starting colorectal cancer (CRC) screening before age 50 years for African Americans, but there are few data on screening uptake and yield in this population. We performed a prospective study of fecal immunochemical test (FIT) sc...
Author(s): Levin TR; Jensen CD; Chawla NM; Sakoda LC; Lee JK; Zhao WK; Landau MA; Herm A; Eby E; Quesenberry CP; Corley DA
Gastroenterology. 2020 Jul 15.
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Standardized reporting and management of suspicious findings on chest computed tomography is associated with improved lung cancer diagnosis in an observational study
Follow-up of chest computed tomography (CT) findings suspicious for lung cancer may be delayed because of inadequate documentation. Standardized reporting and follow-up may reduce time to diagnosis and care for lung cancer. We implemented a reporting syst...
Author(s): Urbania TH; Dusendang JR; Herrinton LJ; Alexeeff S; Corley DA; Ely S; Patel A; Osinski T; Sakoda LC
Chest. 2020 Jun 17.
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Association of Azithromycin Use With Cardiovascular Mortality
Azithromycin is one of the most commonly prescribed antibiotics in the US. It has been associated with an increased risk of cardiovascular death in some observational studies. To estimate the relative and absolute risks of cardiovascular and sudden cardia...
Author(s): Zaroff JG; Cheetham TC; Palmetto N; Almers L; Quesenberry C; Schneider J; Gatto N; Corley DA
JAMA Netw Open. 2020 Jun 01;3(6):e208199. Epub 2020-06-01.
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Validation of an Algorithm to Identify Patients at Risk for Colorectal Cancer Based on Laboratory Test and Demographic Data in Diverse, Community-Based Population
Approximately 30%-40% of screening-eligible adults in the United States are not up to date with colorectal cancer (CRC) screening. We aimed to validate a predictive score, generated by a machine learning algorithm with common laboratory test data, to iden...
Author(s): Schneider J; Layefsky E; Udaltsova N; Levin TR; Corley DA
Clin Gastroenterol Hepatol. 2020 Apr 29.
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COVID-19: What Should Clinicians and Scientists Do and When?
Author(s): Corley DA; Peek RM
Gastroenterology. 2020 Mar 19.
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COVID-19: Long-term Planning for Procedure-based Specialties During Extended Mitigation and Suppression Strategies
Author(s): Rouillard S; Liu VX; Corley DA
Gastroenterology. 2020 May 18.
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Evaluation of automated computed tomography segmentation to assess body composition and mortality associations in cancer patients
Body composition from computed tomography (CT) scans is associated with cancer outcomes including surgical complications, chemotoxicity, and survival. Most studies manually segment CT scans, but Automatic Body composition Analyser using Computed tomograph...
Author(s): Cespedes Feliciano EM; Liu V; Caan BJ; et al.
J Cachexia Sarcopenia Muscle. 2020 Apr 20.
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What Is Organized Screening and What Is Its Value?
Most screening in the United States occurs in an opportunistic fashion, although organized screening occurs in some integrated health care systems. Organized colorectal cancer (CRC) screening consists of an explicit screening policy, defined target popula...
Author(s): Dominitz JA; Levin TR
Gastrointest Endosc Clin N Am. 2020 Jul;30(3):393-411. Epub 2020-04-16.
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Proton Pump Inhibitor Use and Risk of Gastric, Colorectal, Liver, and Pancreatic Cancers in a Community-Based Population
Proton pump inhibitors (PPIs) are commonly used for gastrointestinal disorders; given they increase the systemic levels of gastrin, a trophic hormone, there is a concern about their carcinogenicity. This study evaluated the associations PPI use and the ri...
Author(s): Lee JK; Merchant SA; Schneider JL; Jensen CD; Fireman BH; Quesenberry CP; Corley DA
Am J Gastroenterol. 2020 Mar 20.
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Election of Anil Rustgi and Raymond DuBois to the National Academy of Medicine
Author(s): Corley DE; Peek RM
Gastroenterology. 2020 Apr;158(5):1196. Epub 2020-03-04.
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Impact of observational training on endoscopic mucosal resection outcomes and competency for large colorectal polyps: single endoscopist experience
Background and study aims Endoscopic mucosal resection (EMR) is standard treatment for large colorectal polyps. However, it is a specialized technique with limited data on the effectiveness of training methods to acquire this skill. The aim of this study...
Author(s): Lee JK; Kidambi TD; Kaltenbach T; Bhat YM; Shergill A; McQuaid KR; Terdiman JP; Soetikno RM
Endosc Int Open. 2020 Mar;8(3):E346-E353. Epub 2020-02-21.
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Natural language processing for the accurate identification of colorectal cancer mismatch repair status in Lynch syndrome screening
Author(s): Li D; Udaltsova N; Layefsky E; Doan C; Corley DA
Clin Gastroenterol Hepatol. 2020 Feb 06.
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