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Cardiovascular Publications


A Natural Language Processing-Based Approach for Identifying Hospitalizations for Worsening Heart Failure Within an Integrated Health Care Delivery System

The current understanding of epidemiological mechanisms and temporal trends in hospitalizations for worsening heart failure (WHF) is based on claims and national reporting databases. However, these data sources are inherently limited by the accuracy and c...
Author(s): Ambrosy AP; Go AS; et al.

JAMA Netw Open. 2021 Nov 01;4(11):e2135152. Epub 2021-11-01.

PubMed abstract

Research Priorities in the Secondary Prevention of Atrial Fibrillation: A National Heart, Lung, and Blood Institute Virtual Workshop Report

There has been sustained focus on the secondary prevention of coronary heart disease and heart failure; yet, apart from stroke prevention, the evidence base for the secondary prevention of atrial fibrillation (AF) recurrence, AF progression, and AF-relate...
Author(s): Benjamin EJ; Go AS; et al.

J Am Heart Assoc. 2021 Aug 17;10(16):e021566. Epub 2021-08-05.

PubMed abstract

Covid-19 and Risk of Venous Thromboembolism in Ethnically Diverse Populations

Limited existing data suggest the novel coronavirus disease 2019 (Covid-19) may increase risk for venous thromboembolism (VTE) but information from large, ethnically diverse populations with appropriate controls are lacking. Does the rate of VTE among adu...
Author(s): Go AS; Reynolds K; Tabada GH; Prasad PA; Sung SH; Garcia E; Portugal C; Fan D; Pai AP; Fang MC

Chest. 2021 Jul 19.

PubMed abstract

Relative-Intensity Physical Activity and Its Association With Cardiometabolic Disease

Author(s): Siddique J; Welch WA; Aaby D; Sternfeld B; Pettee Gabriel K; Carnethon MR; Rana JS; Sidney S

J Am Heart Assoc. 2021 Jul 20;10(14):e019174. Epub 2021-07-14.

PubMed abstract

Establishing a Carotid Artery Stenosis Disease Cohort for Comparative Effectiveness Research Using Natural Language Processing

Investigation of asymptomatic carotid stenosis treatment is hindered by the lack of a contemporary population-based disease cohort. We describe the use of natural language processing (NLP) to identify stenosis in patients undergoing carotid imaging. Adult...
Author(s): Chang RW; Tucker LY; Rothenberg KA; Lancaster EM; Avins AL; Kuang HC; Faruqi RM; Nguyen-Huynh MN

J Vasc Surg. 2021 Jun 25.

PubMed abstract

Safety and Efficacy of Intravenous Ferric Derisomaltose Compared to Iron Sucrose for Iron Deficiency Anemia in Patients with Chronic Kidney Disease With and Without Heart Failure

Ferric derisomaltose (FDI) is an intravenous (IV) high-dose iron formulation approved in the US for the treatment of iron deficiency anemia in adults who are intolerant of/have had an unsatisfactory response to oral iron, or who have non-dialysis-dependen...
Author(s): Ambrosy AP; von Haehling S; Kalra PR; Court E; Bhandari S; McDonagh T; Cleland JGF

Am J Cardiol. 2021 Jun 20.

PubMed abstract

Primary Nephrotic Syndrome and Risks of ESKD, Cardiovascular Events, and Death: The Kaiser Permanente Nephrotic Syndrome Study

Little population-based data exist about adults with primary nephrotic syndrome. To evaluate kidney, cardiovascular, and mortality outcomes in adults with primary nephrotic syndrome, we identified adults within an integrated health care delivery system (K...
Author(s): Go AS; Parikh RV; et al.

J Am Soc Nephrol. 2021 Jun 18.

PubMed abstract

Changes in Patterns of Hospital Visits for Acute Myocardial Infarction or Ischemic Stroke During COVID-19 Surges

Author(s): Solomon MD; Nguyen-Huynh M; Leong TK; Alexander J; Rana JS; Klingman J; Go AS

JAMA. 2021 Jun 02.

PubMed abstract

Ten-year Thyroid Cancer Incidence in an Integrated Healthcare Delivery System

The incidence of papillary thyroid cancer (PTC) has increased in recent decades, but data from community-based settings are limited. This study characterizes PTC trends in a large, integrated healthcare system over 10 years. The annual incidence of PTC (2...
Author(s): Kim SJ; Durr ML; Darbinian JA; Sakoda LC; Meltzer CJ; Arzumanyan H; Wang KH; Lin JK; Gurushanthaiah D; Lo JC

Perm J. 2021 May;25.

PubMed abstract

Potential accuracy of prehospital NIHSS-based triage for selection of candidates for acute endovascular stroke therapy

Whether patients with acute stroke and large vessel occlusion (LVO) benefit from prehospital identification and diversion by emergency medical services (EMS) to an endovascular stroke therapy (EST)-capable center is controversial. We sought to estimate th...
Author(s): Klingman JG; Alexander JG; Vinson DR; Klingman LE; Nguyen-Huynh MN

J Am Coll Emerg Physicians Open. 2021 Jun;2(3):e12441. Epub 2021-05-01.

PubMed abstract

Progression of atypical femur stress fracture after discontinuation of bisphosphonate therapy

Atypical femur fracture (AFF) is an uncommon complication of long-term bisphosphonate use, but the risk declines substantially after treatment cessation. We report a case of a 70-year-old woman with osteopenia treated with alendronate for 9 years who pres...
Author(s): Gu KD; Ettinger B; Grimsrud CD; Lo JC

Osteoporos Int. 2021 Apr 29.

PubMed abstract

The Risks of Polycystic Ovary Syndrome and Diabetes Vary by Ethnic Subgroup Among Young Asian Women

Author(s): Guo L; Gordon NP; Chandra M; Dayo O; Lo JC

Diabetes Care. 2021 Apr 26.

PubMed abstract

Blood Pressure Levels in Young Adulthood and Midlife Stroke Incidence in a Diverse Cohort

We examined the longitudinal association between blood pressure (BP) and stroke incidence in young and middle-aged adults. BP measured during 9 examinations of the CARDIA study (Coronary Artery Risk Development in Young Adults) from 1985-1986 to 2015-2016...
Author(s): Gerber Y; Nguyen-Huynh MN; Sidney S; et al.

Hypertension. 2021 Mar 29:HYPERTENSIONAHA12016535.

PubMed abstract

Particulate Matter and Cardiovascular Risk in Adults with Chronic Obstructive Pulmonary Disease

People with chronic obstructive pulmonary disease have increased risk of cardiovascular disease and may be more susceptible to air pollution exposure. However, no study has examined the association between long-term fine particulate matter exposure (<2.5 ...
Author(s): Alexeeff SE; Deosaransingh K; Liao NS; Van Den Eeden SK; Schwartz J; Sidney S

Am J Respir Crit Care Med. 2021 Mar 04.

PubMed abstract

Non-alcoholic fatty liver disease and cognitive function in middle-aged adults: the CARDIA study

Non-alcoholic fatty liver disease (NAFLD) is associated with cardiovascular disease (CVD) risk factors that have been linked to cognitive decline. Whether NAFLD is associated with cognitive performance in midlife remains uncertain. Coronary Artery Risk De...
Author(s): Gerber Y; VanWagner LB; Yaffe K; Terry JG; Rana JS; Reis JP; Sidney S

BMC Gastroenterol. 2021 Mar 02;21(1):96. Epub 2021-03-02.

PubMed abstract

The Association of Lactation Duration with Visceral and Pericardial Fat Volumes in Parous Women: the CARDIA Study

Lactation is associated with lower risks for cardiovascular disease in women. Organ-related adiposity, which plays significant roles in the development of cardiometabolic diseases, could help explain this observation. We evaluated the association of lacta...
Author(s): Appiah D; Lewis CE; Jacobs DR; Shikany JM; Quesenberry CP; Gross M; Carr J; Sidney S; Gunderson EP

J Clin Endocrinol Metab. 2021 Feb 01.

PubMed abstract

Variation in fracture risk estimation among East Asian women

Bone mineral density (BMD) testing and fracture risk calculation help clinicians assess fracture risk and counsel patients. However, predicted fracture risks and outcomes for US East Asian individuals remain understudied. Retrospective cohort study. Using...
Author(s): Lo JC; Nath S; Patel M; Chandra M; Yang B; Weintraub MR; Ettinger B

Am J Manag Care. 2021 03 01;27(3):e97-e100. Epub 2021-03-01.

PubMed abstract

Timing of Dialysis Initiation and End-Stage Kidney Disease Incidence-Reply

Author(s): Hsu CY; Go AS

JAMA Intern Med. 2021 Feb 15.

PubMed abstract

Risk of atherosclerotic cardiovascular disease by cardiovascular health metric categories in approximately 1 million patients

Author(s): Rana JS; Liu JY; Moffet HH; Karter AJ; Nasir K; Solomon MD; Jaffe MG; Ambrosy AP; Go AS; Sidney S

Eur J Prev Cardiol. 2020 Feb 07.

PubMed abstract

Gestational Diabetes History and Glucose Tolerance After Pregnancy Associated With Coronary Artery Calcium in Women During Midlife: The CARDIA Study

Author(s): Gunderson EP; Sun B; Catov JM; Carnethon M; Lewis CE; Allen NB; Sidney S; Wellons M; Rana JS; Hou L; Carr JJ

Circulation. 2021 Feb 01.

PubMed abstract

Rationale and Design of the Pragmatic Randomized Trial of Icosapent Ethyl for High Cardiovascular Risk Adults (MITIGATE)

The MITIGATE study aims to evaluate the real-world clinical effectiveness of pre-treatment with icosapent ethyl (IPE), compared with usual care, on laboratory-confirmed viral upper respiratory infection (URI)-related morbidity and mortality in adults with...
Author(s): Ambrosy AP; Skarbinski J; Go AS; et al.

Am Heart J. 2021 Jan 28.

PubMed abstract

Association of infant diet with subsequent obesity at 2-5 years among children exposed to gestational diabetes: the SWIFT study

This longitudinal analysis evaluated the independent and joint associations of any breastfeeding (BF) or exclusive BF (EBF) and intake of sugar-sweetened beverages (SSBs) and 100% fruit juice from birth to 1 year with subsequent overweight and obesity amo...
Author(s): Vandyousefi S; Davis JN; Gunderson EP

Diabetologia. 2021 Jan 26.

PubMed abstract

Contemporary Reevaluation of Race and Ethnicity With Outcomes in Heart Failure

Background Variation in outcomes by race/ethnicity in adults with heart failure (HF) has been previously observed. Identifying factors contributing to these variations could help target interventions. We evaluated the association of race/ethnicity with HF...
Author(s): Savitz ST; Leong T; Sung SH; Lee K; Rana JS; Tabada G; Go AS

J Am Heart Assoc. 2021 Jan 21:e016601.

PubMed abstract

Long-Term PM2.5 Exposure and Risks of Ischemic Heart Disease and Stroke Events: Review and Meta-Analysis

Background Fine particulate matter <2.5 µm in diameter (PM2.5) has known effects on cardiovascular morbidity and mortality. However, no study has quantified and compared the risks of incident myocardial infarction, incident stroke, ischemic heart disease ...
Author(s): Alexeeff SE; Liao NS; Liu X; Van Den Eeden SK; Sidney S

J Am Heart Assoc. 2020 Dec 31:e016890.

PubMed abstract

Response by Flint et al to Letter Regarding Article, "Risk of Distal Embolization From tPA (Tissue-Type Plasminogen Activator) Administration Prior to Endovascular Stroke Treatment"

Author(s): Flint AC; Avins AL; Nguyen-Huynh MN

Stroke. 2021 Jan;52(1):e39-e40. Epub 2020-12-28.

PubMed abstract