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Cardiovascular Publications


Blood Pressure Levels in Young Adulthood and Midlife Stroke Incidence in a Diverse Cohort

We examined the longitudinal association between blood pressure (BP) and stroke incidence in young and middle-aged adults. BP measured during 9 examinations of the CARDIA study (Coronary Artery Risk Development in Young Adults) from 1985-1986 to 2015-2016...
Author(s): Gerber Y; Nguyen-Huynh MN; Sidney S; et al.

Hypertension. 2021 Mar 29:HYPERTENSIONAHA12016535.

PubMed abstract

Particulate Matter and Cardiovascular Risk in Adults with Chronic Obstructive Pulmonary Disease

People with chronic obstructive pulmonary disease have increased risk of cardiovascular disease and may be more susceptible to air pollution exposure. However, no study has examined the association between long-term fine particulate matter exposure (<2.5 ...
Author(s): Alexeeff SE; Deosaransingh K; Liao NS; Van Den Eeden SK; Schwartz J; Sidney S

Am J Respir Crit Care Med. 2021 Mar 04.

PubMed abstract

Non-alcoholic fatty liver disease and cognitive function in middle-aged adults: the CARDIA study

Non-alcoholic fatty liver disease (NAFLD) is associated with cardiovascular disease (CVD) risk factors that have been linked to cognitive decline. Whether NAFLD is associated with cognitive performance in midlife remains uncertain. Coronary Artery Risk De...
Author(s): Gerber Y; VanWagner LB; Yaffe K; Terry JG; Rana JS; Reis JP; Sidney S

BMC Gastroenterol. 2021 Mar 02;21(1):96. Epub 2021-03-02.

PubMed abstract

The Association of Lactation Duration with Visceral and Pericardial Fat Volumes in Parous Women: the CARDIA Study

Lactation is associated with lower risks for cardiovascular disease in women. Organ-related adiposity, which plays significant roles in the development of cardiometabolic diseases, could help explain this observation. We evaluated the association of lacta...
Author(s): Appiah D; Lewis CE; Jacobs DR; Shikany JM; Quesenberry CP; Gross M; Carr J; Sidney S; Gunderson EP

J Clin Endocrinol Metab. 2021 Feb 01.

PubMed abstract

Variation in fracture risk estimation among East Asian women

Bone mineral density (BMD) testing and fracture risk calculation help clinicians assess fracture risk and counsel patients. However, predicted fracture risks and outcomes for US East Asian individuals remain understudied. Retrospective cohort study. Using...
Author(s): Lo JC; Nath S; Patel M; Chandra M; Yang B; Weintraub MR; Ettinger B

Am J Manag Care. 2021 03 01;27(3):e97-e100. Epub 2021-03-01.

PubMed abstract

Timing of Dialysis Initiation and End-Stage Kidney Disease Incidence-Reply

Author(s): Hsu CY; Go AS

JAMA Intern Med. 2021 Feb 15.

PubMed abstract

Risk of atherosclerotic cardiovascular disease by cardiovascular health metric categories in approximately 1 million patients

Author(s): Rana JS; Liu JY; Moffet HH; Karter AJ; Nasir K; Solomon MD; Jaffe MG; Ambrosy AP; Go AS; Sidney S

Eur J Prev Cardiol. 2020 Feb 07.

PubMed abstract

Gestational Diabetes History and Glucose Tolerance After Pregnancy Associated With Coronary Artery Calcium in Women During Midlife: The CARDIA Study

Author(s): Gunderson EP; Sun B; Catov JM; Carnethon M; Lewis CE; Allen NB; Sidney S; Wellons M; Rana JS; Hou L; Carr JJ

Circulation. 2021 Feb 01.

PubMed abstract

Rationale and Design of the Pragmatic Randomized Trial of Icosapent Ethyl for High Cardiovascular Risk Adults (MITIGATE)

The MITIGATE study aims to evaluate the real-world clinical effectiveness of pre-treatment with icosapent ethyl (IPE), compared with usual care, on laboratory-confirmed viral upper respiratory infection (URI)-related morbidity and mortality in adults with...
Author(s): Ambrosy AP; Skarbinski J; Go AS; et al.

Am Heart J. 2021 Jan 28.

PubMed abstract

Association of infant diet with subsequent obesity at 2-5 years among children exposed to gestational diabetes: the SWIFT study

This longitudinal analysis evaluated the independent and joint associations of any breastfeeding (BF) or exclusive BF (EBF) and intake of sugar-sweetened beverages (SSBs) and 100% fruit juice from birth to 1 year with subsequent overweight and obesity amo...
Author(s): Vandyousefi S; Davis JN; Gunderson EP

Diabetologia. 2021 Jan 26.

PubMed abstract

Contemporary Reevaluation of Race and Ethnicity With Outcomes in Heart Failure

Background Variation in outcomes by race/ethnicity in adults with heart failure (HF) has been previously observed. Identifying factors contributing to these variations could help target interventions. We evaluated the association of race/ethnicity with HF...
Author(s): Savitz ST; Leong T; Sung SH; Lee K; Rana JS; Tabada G; Go AS

J Am Heart Assoc. 2021 Jan 21:e016601.

PubMed abstract

Long-Term PM2.5 Exposure and Risks of Ischemic Heart Disease and Stroke Events: Review and Meta-Analysis

Background Fine particulate matter <2.5 µm in diameter (PM2.5) has known effects on cardiovascular morbidity and mortality. However, no study has quantified and compared the risks of incident myocardial infarction, incident stroke, ischemic heart disease ...
Author(s): Alexeeff SE; Liao NS; Liu X; Van Den Eeden SK; Sidney S

J Am Heart Assoc. 2020 Dec 31:e016890.

PubMed abstract

Response by Flint et al to Letter Regarding Article, "Risk of Distal Embolization From tPA (Tissue-Type Plasminogen Activator) Administration Prior to Endovascular Stroke Treatment"

Author(s): Flint AC; Avins AL; Nguyen-Huynh MN

Stroke. 2021 Jan;52(1):e39-e40. Epub 2020-12-28.

PubMed abstract

Breast Arterial Calcification Is Not Associated with Mild Cognitive Impairment or Incident All-Cause Dementia Among Postmenopausal Women: The MINERVA Study

Background: Since vascular risk factors are implicated in cognitive decline, and breast arterial calcification (BAC) is related to vascular risk, we postulated that BAC may be associated with cognitive impairment and dementia. Methods: We used a multiethn...
Author(s): Iribarren C; Chandra M; Molloi S; Sanchez G; Azamian-Bidgoli F; Cho HM; Ding H; Yaffe K

J Womens Health (Larchmt). 2020 Dec 07.

PubMed abstract

Risk of complete atypical femur fracture with Oral bisphosphonate exposure beyond three years

Bisphosphonate (BP) therapy has been associated with atypical femur fracture (AFF). However, the threshold of treatment duration leading to increased AFF risk is unclear. In a retrospective cohort of older women initiating BP, we compared the AFF risk ass...
Author(s): Lo JC; Neugebauer RS; Ettinger B; Chandra M; Hui RL; Ott SM; Grimsrud CD; Izano MA

BMC Musculoskelet Disord. 2020 Dec 03;21(1):801. Epub 2020-12-03.

PubMed abstract

Improving adherence to guideline-directed medical therapies and outcomes in the developing world: A call to end global inequities in heart failure

Author(s): Chioncel O; Ambrosy AP

Int J Cardiol. 2020 Dec 02.

PubMed abstract

Validation Study of Kaiser Permanente Bedside Dysphagia Screening Tool in Acute Stroke Patients

Dysphagia occurs in up to 50% of patients with acute stroke symptoms, resulting in increased aspiration pneumonia rates and mortality. The purpose of this study was to validate a health system's dysphagia (swallow) screening tool used since 2007 on all pa...
Author(s): Finnegan BS; Meighan MM; Warren NC; Hatfield MK; Alexeeff S; Lipiz J; Nguyen-Huynh M

Perm J. 2020 Dec;24:1.

PubMed abstract

No Association Between Bone Mineral Density and Breast Arterial Calcification Among Postmenopausal Women

The association between bone mineral density (BMD) and breast arterial calcification (BAC) remains poorly understood and controversial. The objective of this article is to examine the association between BMD and BAC in a large cohort of postmenopausal wom...
Author(s): Iribarren C; Chandra M; Molloi S; Sam D; Sanchez G; Bidgoli FA; Cho HM; Ding H; Lo JC

J Endocr Soc. 2020 Feb 01;4(2):bvz026. Epub 2019-11-27.

PubMed abstract

Implication of Trends in Timing of Dialysis Initiation for Incidence of End-stage Kidney Disease

In the last 2 decades, there have been notable changes in the level of estimated glomerular filtration rate (eGFR) at which patients initiate long-term dialysis in the US and around the world. How changes over time in the likelihood of dialysis initiation...
Author(s): Hsu CY; Parikh RV; Pravoverov LN; Zheng S; Glidden DV; Tan TC; Go AS

JAMA Intern Med. 2020 Oct 12.

PubMed abstract

Bone Mineral Density in Older U.S. Filipino, Chinese, Japanese, and White Women

Bone mineral density (BMD) reference data exist for U.S. White, Black, and Hispanic (Mexican American) populations but not for U.S. Asians. Few studies have compared BMD findings among different U.S. Asian ethnicities. Retrospective observational study. L...
Author(s): Lo JC; Chandra M; Lee C; Darbinian JA; Ramaswamy M; Ettinger B

J Am Geriatr Soc. 2020 Oct 12.

PubMed abstract

The Heart Failure Readmission Intervention by Variable Early Follow-up (THRIVE) Study: A Pragmatic Randomized Trial

In-person clinic follow-up within 7 days after discharge from a heart failure hospitalization is associated with lower 30-day readmission. However, health systems and patients may find it difficult to complete an early postdischarge clinic visit, especial...
Author(s): Lee KK; Thomas RC; Tan TC; Leong TK; Steimle A; Go AS

Circ Cardiovasc Qual Outcomes. 2020 Sep 24:CIRCOUTCOMES120006553.

PubMed abstract

Kidney Function and Potassium Monitoring After Initiation of Renin-Angiotensin-Aldosterone System Blockade Therapy and Outcomes in 2 North American Populations

Clinical practice guidelines recommend routine kidney function and serum potassium testing within 30 days of initiating ACE (angiotensin-converting enzyme) inhibitor or angiotensin II receptor blocker therapy. However, evidence is lacking about whether fo...
Author(s): Parikh RV; Go AS; et al.

Circ Cardiovasc Qual Outcomes. 2020 Sep;13(9):e006415. Epub 2020-09-02.

PubMed abstract

Angiotensin Receptor-Neprilysin Inhibition Based on History of Heart Failure and Use of Renin-Angiotensin System Antagonists

The PIONEER-HF (comParIson Of sacubitril/valsartaN versus Enalapril on Effect on nt-pRo-bnp in patients stabilized from an acute Heart Failure episode) trial demonstrated the efficacy and safety of sacubitril/valsartan (S/V) in stabilized patients with ac...
Author(s): Ambrosy AP; Braunwald E; Morrow DA; DeVore AD; McCague K; Meng X; Duffy CI; Rocha R; Velazquez EJ; PIONEER-HF Investigators

J Am Coll Cardiol. 2020 Sep 01;76(9):1034-1048.

PubMed abstract

Establishing a Graduate Medical Education Task Force for the American Medical Women's Association

Author(s): Lo JC

Perm J. 2020 09;24:1-2.

PubMed abstract

Community-Based Epidemiology of Hospitalized Acute Kidney Injury

Acute kidney injury (AKI) may lead to short- and long-term consequences in children, but its epidemiology has not been well described at a population level and outside of ICU settings. In a large, diverse pediatric population receiving care within an inte...
Author(s): Parikh RV; Tan TC; Salyer AS; Auron A; Kim PS; Ku E; Go AS

Pediatrics. 2020 Sep;146(3). Epub 2020-08-11.

PubMed abstract