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Health Care Delivery Publications


Cardiovascular Disease Risk Factors Among Middle-Aged and Older Adult Vietnamese American Members of a Northern California Health Plan

There is increasing recognition that cardiovascular disease (CVD) risk factors vary by Asian subgroups. We examined CVD risk factor prevalence among Vietnamese adults in a northern California health plan. We used electronic health record data to examine s...
Author(s): Haysbert, Donna B; Lo, Joan C; Ramalingam, Nirmala D; Gordon, Nancy P

Public Health Rep. 2023 Jan-Feb;138(1):123-130. Epub 2022-02-20.

PubMed abstract

Risk of hospitalization in a sample of COVID-19 patients with and without chronic obstructive pulmonary disease

Patients with chronic obstructive pulmonary disease (COPD) may have worse coronavirus disease-2019 (COVID-19)-related outcomes. We compared COVID-19 hospitalization risk in patients with and without COPD. This retrospective cohort study included patients ...
Author(s): Myers, Laura C; Murray, Richard; Donato, Bonnie; Liu, Vincent X; Kipnis, Patricia; Shaikh, Asif; Franchino-Elder, Jessica

Respir Med. 2023 Jan;206:107064. Epub 2022-11-26.

PubMed abstract

Incidence and Medical Hospitalization Rates of Patients With Pediatric Eating Disorders

Objective Eating disorders typically onset in preadolescence and adolescence and cause negative mental and physical health sequelae over the life span. This study examined the incidence and medical hospitalization rates of pediatric eating disorders in an...
Author(s): Lau, Josephine S; Uong, Stephen P; Hartman, Lauren; Eaton, Abigail; Schmittdiel, Julie

Perm J. 2022 Dec 19;26(4):56-61. Epub 2022-11-18.

PubMed abstract

Persistent Steroid Exposure Before Coronavirus Disease 2019 Diagnosis and Risk of Hospitalization in Patients With Chronic Obstructive Pulmonary Disease

It is unclear whether persistent inhaled steroid exposure in chronic obstructive pulmonary disease (COPD) patients before coronavirus disease 2019 (COVID-19) is associated with hospitalization risk. To examine the association between persistent steroid ex...
Author(s): Myers, Laura C; Murray, Richard K; Donato, Bonnie M K; Liu, Vincent X; Kipnis, Patricia; Kipnis, Patricia; Shaikh, Asif; Franchino-Elder, Jessica

Chronic Obstr Pulm Dis. 2022 Dec 05.

PubMed abstract

Association Between Vaccination Against COVID-19 and Postmenopausal Bleeding

Author(s): Suh-Burgmann, Elizabeth J; Tierney, Cassidy; Hung, Yun-Yi; Schmittdiel, Julie A

Am J Obstet Gynecol. 2022 Dec;227(6):907-908. Epub 2022-07-12.

PubMed abstract

The association between video or telephone telemedicine visit type and orders in primary care

Telemedicine is increasingly relied upon for care delivery in primary care, but the impact of visit type on clinical ordering behavior is uncertain. Within Kaiser Permanente Northern California, we identified patients who self-scheduled and completed tele...
Author(s): Juergens, Nathan; Huang, Jie; Gopalan, Anjali; Muelly, Emilie; Reed, Mary

BMC Med Inform Decis Mak. 2022 Nov 19;22(1):302. Epub 2022-11-19.

PubMed abstract

Cross-Sectional Association of Patient Language and Patient-Provider Language Concordance with Video Telemedicine Use Among Patients with Limited English Proficiency

Telemedicine's dramatic increase during the COVID-19 pandemic elevates the importance of addressing patient-care gaps in telemedicine, especially for patients with limited English proficiency. To examine the associations of patient language and patient-pr...
Author(s): Hsueh, Loretta; Huang, Jie; Millman, Andrea K; Gopalan, Anjali; Parikh, Rahul K; Teran, Silvia; Reed, Mary E

J Gen Intern Med. 2022 Nov 10:1-8.

PubMed abstract

Prevalence of sleep-related problems and risks in a community-dwelling older adult population: a cross-sectional survey-based study

Despite evidence of adverse health consequences of inadequate restorative sleep for older adults, assessment of sleep quantity, quality, and use of sleep aids is not routinely done. We aimed to characterize sleep problems, sleep risks, and advice received...
Author(s): Gordon, Nancy P; Yao, Jimmy H; Brickner, Leslea A; Lo, Joan C

BMC Public Health. 2022 Nov 08;22(1):2045. Epub 2022-11-08.

PubMed abstract

The intensity of anticoagulant dosing in hospitalized patients with COVID-19: An observational, comparative effectiveness study

The question of anticoagulant dosing in hospitalized patients with coronavirus disease-2019 (COVID-19) is unresolved, with randomized trials showing mixed results and heterogeneity of treatment effects for in-hospital death. To examine the association bet...
Author(s): Myers, Laura C; Xu, Stanley; Chen, Aiyu; Greene, John D; Creekmur, Beth; Bruxvoort, Katia; Escobar, Gabriel J; Adams, John L; Langer-Gould, Annette; Liu, Vincent X; Gould, Michael K

J Hosp Med. 2022 Nov 08.

PubMed abstract

Covid-19 Vaccination and the Timing of Surgery Following Covid-19 Infection

To evaluate whether COVID-19 vaccination status or mode of anesthesia modified the temporal harms associated with surgery following coronavirus disease-2019 (COVID-19) infection. Surgery shortly after COVID-19 infection is associated with higher rates of ...
Author(s): Le, Sidney T; Kipnis, Patricia; Cohn, Bradley; Liu, Vincent X

Ann Surg. 2022 11 01;276(5):e265-e272. Epub 2022-07-15.

PubMed abstract

Use of Cannabidiol (CBD) oil in the treatment of PTSD: Study design and rationale for a placebo-controlled randomized clinical trial

The burden of illness for PTSD is staggering and confers significant interference in work, social functioning, as well as increased risk for other physical and mental health problems. Recently, there's been considerable attention paid to the potential the...
Author(s): Telch, Michael J; Fischer, Caitlin M; Zaizar, Eric D; Rubin, Mikael; Papini, Santiago

Contemp Clin Trials. 2022 Nov;122:106933. Epub 2022-09-22.

PubMed abstract

Telemedicine implementation trends in surgical specialties before and after COVID-19 shelter in place: Adjusting to a changing landscape

The COVID-19 pandemic caused a shift from in-person care to telemedicine, providing a unique opportunity to evaluate trends and efficiency of telemedicine usage within surgical subspecialties in a large, integrated health care system before and after shel...
Author(s): Kuehner, Gillian; Wu, Weilu; Choe, Giye; Douaiher, Jeffrey; Reed, Mary

Surgery. 2022 Nov;172(5):1471-1477. Epub 2022-06-13.

PubMed abstract

Prevalence of prediabetes and diabetes vary by ethnicity among U.S. Asian adults at healthy weight, overweight, and obesity ranges: an electronic health record study

Asian adults develop Type 2 diabetes at a lower body mass index (BMI) compared to other racial/ethnic groups. We examined the variation in prevalence of prediabetes and diabetes among Asian ethnic groups within weight strata by comparing middle-aged Chine...
Author(s): Vicks, William S; Lo, Joan C; Guo, Lynn; Rana, Jamal S; Zhang, Sherry; Ramalingam, Nirmala D; Gordon, Nancy P

BMC Public Health. 2022 Oct 22;22(1):1954. Epub 2022-10-22.

PubMed abstract

Quantifying the breadth of antibiotic exposure in sepsis and suspected infection using spectrum scores

A retrospective cohort study. Studies to quantify the breadth of antibiotic exposure across populations remain limited. Therefore, we applied a validated method to describe the breadth of antimicrobial coverage in a multicenter cohort of patients with sus...
Author(s): Smith, Joshua T; Manickam, Raj N; Barreda, Fernando; Greene, John D; Bhimarao, Meghana; Pogue, Jason; Jones, Makoto; Myers, Laura; Prescott, Hallie C; Liu, Vincent X

Medicine (Baltimore). 2022 Oct 14;101(41):e30245.

PubMed abstract

Barriers and Opportunities Regarding Implementation of a Machine Learning-Based Acute Heart Failure Risk Stratification Tool in the Emergency Department

Hospital admissions for patients with acute heart failure (AHF) remain high. There is an opportunity to improve alignment between patient risk and admission decision. We recently developed a machine learning (ML)-based model that stratifies emergency depa...
Author(s): Sax, Dana R; Sturmer, Lillian R; Mark, Dustin G; Rana, Jamal S; Reed, Mary E

Diagnostics (Basel). 2022 Oct 11;12(10). Epub 2022-10-11.

PubMed abstract

Comparing the effectiveness of a brief intervention to reduce unhealthy alcohol use among adult primary care patients with and without depression: A machine learning approach with augmented inverse probability weighting

The combination of unhealthy alcohol use and depression is associated with adverse outcomes including higher rates of alcohol use disorder and poorer depression course. Therefore, addressing alcohol use among individuals with depression may have a substan...
Author(s): Papini, Santiago; Chi, Felicia W; Schuler, Alejandro; Satre, Derek D; Liu, Vincent X; Sterling, Stacy A

Drug Alcohol Depend. 2022 Oct 01;239:109607. Epub 2022-08-27.

PubMed abstract

Identifying modifiable obesogenic behaviors among Latino adolescents in primary pediatric care.

Latino adolescents engage in more obesogenic behaviors, including sedentary behaviors and sugary drink consumption, than White adolescents. However, it is unclear whether engagement in obesogenic behaviors differs within the Latino population. Cross-secti...
Author(s): Rodriguez LA; Gopalan A; Darbinian JA; Chandra M; Greenspan LC; Howell A; Lo JC

Prev Med Rep. 2022 Jul 30;29:101939. doi: 10.1016/j.pmedr.2022.101939. eCollection 2022 Oct.

PubMed abstract

Pulmonary Embolism

Author(s): Vinson, David R; Rouleau, Samuel G; Casey, Scott D

N Engl J Med. 2022 Sep 29;387(13):1242.

PubMed abstract

Predicting Post-Sepsis Cardiovascular Events with Death as a Competing Risk

Author(s): Myers, Laura C; Desai, Manisha; Liu, Vincent X; Walkey, Allan J; Walkey, Allan J; et al.

Ann Am Thorac Soc. 2022 Sep 19.

PubMed abstract

Strategies Facilitating Video Visit Implementation by a Medical Group Serving a Diverse Population

IntroductionVideo visits have created new opportunities to enhance access to care, but limited information exists on strategies medical groups can employ to facilitate video visit use by higher-risk patients. Our objective was to identify generalizable st...
Author(s): Lieu, Tracy A; Altschuler, Andrea; Hsueh, Loretta; Warton, E Margaret; Levan, Christine; Dixon, Matthew; San, Karen; Awsare, Sameer; Chen, Yi-Fen Irene; Lee, Edward R; Reed, Mary E

Perm J. 2022 Sep 14;26(3):20-29. Epub 2022-07-20.

PubMed abstract

Primary Care Visits Are Timelier When Patients Choose Telemedicine: A Cross-Sectional Observational Study

Introduction: Telemedicine could increase timely access to primary care-a key dimension of care quality. Methods: Among patient-scheduled appointments with their own primary care providers using the online portal in a large integrated health care delivery...
Author(s): Graetz, Ilana; Huang, Jie; Muelly, Emilie; Gopalan, Anjali; Reed, Mary E

Telemed J E Health. 2022 Sep;28(9):1374-1378. Epub 2022-02-03.

PubMed abstract

Risk of severe COVID-19 infection among adults with prior exposure to children

Susceptibility and severity of COVID-19 infection vary widely. Prior exposure to endemic coronaviruses, common in young children, may protect against SARS-CoV-2. We evaluated risk of severe COVID-19 among adults with and without exposure to young children...
Author(s): Solomon, Matthew D; Escobar, Gabriel J; Lu, Yun; Schlessinger, David; Steinman, Jonathan B; Steinman, Lawrence; Lee, Catherine; Liu, Vincent X

Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2204141119. Epub 2022-07-27.

PubMed abstract

Racial and Ethnic Differences in Medication Initiation Among Adults Newly Diagnosed with Type 2 Diabetes

Given persistent racial/ethnic differences in type 2 diabetes outcomes and the lasting benefits conferred by early glycemic control, we examined racial/ethnic differences in diabetes medication initiation during the year following diagnosis. Among adults ...
Author(s): Gopalan, Anjali; Winn, Aaron N; Karter, Andrew J; Laiteerapong, Neda

J Gen Intern Med. 2022 Aug 04.

PubMed abstract

Associations Between Different Self-reported Social Risks and Neighborhood-level Resources in Medicaid Patients

Adverse social conditions are a key contributor to health disparities. Improved understanding of how social risk factors interact with each other and with neighborhood characteristics may inform efforts to reduce health disparities. A questionnaire of 29,...
Author(s): Miller-Rosales, Chris; McCloskey, Jodi; Uratsu, Connie S; Ralston, James D; Bayliss, Elizabeth A; Grant, Richard W

Med Care. 2022 08 01;60(8):563-569. Epub 2022-05-30.

PubMed abstract

Temporal Trends in Antimicrobial Prescribing During Hospitalization for Potential Infection and Sepsis

Some experts have cautioned that national and health system emphasis on rapid administration of antimicrobials for sepsis may increase overall antimicrobial use even among patients without sepsis. To assess whether temporal changes in antimicrobial timing...
Author(s): Prescott, Hallie C; Liu, Vincent X; et al.

JAMA Intern Med. 2022 08 01;182(8):805-813.

PubMed abstract