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Health Care Delivery Publications


Real-Time Patient-Provider Video Telemedicine Integrated with Clinical Care

Author(s): Reed ME; Parikh R; Huang J; Ballard DW; Barr I; Wargon C

N Engl J Med. 2018 10 11;379(15):1478-1479.

PubMed abstract

Anti-TNF and Physiologic Measures of Metabolic Disease in Rheumatoid Arthritis

Author(s): Herrinton LJ; Ray GT; Wu JJ; Fireman B; Liu L; Goldfien R; Curtis JR

J Clin Rheumatol. 2018 Nov 07.

PubMed abstract

Exploring how patients understand and assess their diabetes control

Poor understanding of diabetes management targets is associated with worse disease outcomes. Patients may use different information than providers to assess their diabetes control. In this study, we identify the information patients use to gauge their cur...
Author(s): Gopalan A; Kellom K; McDonough K; Schapira MM

BMC Endocr Disord. 2018 Nov 06;18(1):79. Epub 2018-11-06.

PubMed abstract

Mobile-accessible personal health records increase the frequency and timeliness of PHR use for patients with diabetes

Personal health records (PHRs) offer patients a portal to view lab results, communicate with their doctors, and refill medications. Expanding PHR access to mobile devices could increase patients' engagement with their PHRs. We examined whether access to a...
Author(s): Graetz I; Huang J; Brand R; Hsu J; Reed ME

J Am Med Inform Assoc. 2018 Oct 24.

PubMed abstract

Understanding functional and social risk characteristics of frail older adults: a cross-sectional survey study

Frailty is a condition of increasing importance, given the aging adult population. With an anticipated shortage of geriatricians, primary care physicians will increasingly need to manage care for frail adults with complex functional risks and social-econo...
Author(s): Lee DR; Santo EC; Lo JC; Ritterman Weintraub ML; Patton M; Gordon NP

BMC Fam Pract. 2018 Oct 19;19(1):170. Epub 2018-10-19.

PubMed abstract

Using Neighborhood-Level Census Data to Predict Diabetes Progression in Patients with Laboratory-Defined Prediabetes

Research on predictors of clinical outcomes usually focuses on the impact of individual patient factors, despite known relationships between neighborhood environment and health. To determine whether US census information on where a patient resides is asso...
Author(s): Schmittdiel JA; Dyer WT; Marshall CJ; Bivins R

Perm J. 2018 Oct 05;22. Epub 2018-10-05.

PubMed abstract

Association of Medical Scribes in Primary Care With Physician Workflow and Patient Experience

Widespread adoption of electronic health records (EHRs) in medical care has resulted in increased physician documentation workload and decreased interaction with patients. Despite the increasing use of medical scribes for EHR documentation assistance, few...
Author(s): Mishra P; Kiang JC; Grant RW

JAMA Intern Med. 2018 Sep 17.

PubMed abstract

Association between Inhaled Corticosteroid Use and Pulmonary Nontuberculous Mycobacterial Infection

Nontuberculous mycobacterial (NTM) pulmonary disease prevalence is increasing. To determine the association between the use of inhaled corticosteroids (ICS) and the likelihood of NTM pulmonary infection among individuals with treated airways disease. We c...
Author(s): Liu VX; Winthrop KL; Lu Y; Sharifi H; Nasiri HU; Ruoss SJ

Ann Am Thorac Soc. 2018 Sep 14.

PubMed abstract

Prevalence and predictors of delayed clinical diagnosis of Type 2 diabetes: a longitudinal cohort study

To examine the prevalence and person-level predictors of undiagnosed Type 2 diabetes among adults with elevated HbA1c values. We identified adults without diabetes who had a first elevated HbA1c (index HbA1c ≥ 48 mmol/mol; ≥ 6.5%) between January 2014 and...
Author(s): Gopalan A; Mishra P; Alexeeff SE; Blatchins MA; Kim E; Man AH; Grant RW

Diabet Med. 2018 Sep 03.

PubMed abstract

The Legacy Effect in Type 2 Diabetes: Impact of Early Glycemic Control on Future Complications (the Diabetes & Aging Study)

To examine for a legacy effect of early glycemic control on diabetic complications and death. This cohort study of managed care patients with newly diagnosed type 2 diabetes and 10 years of survival (1997-2013, average follow-up 13.0 years, N = 34,737) ex...
Author(s): Laiteerapong N; Ham SA; Gao Y; Moffet HH; Liu JY; Huang ES; Karter AJ

Diabetes Care. 2018 Aug 13.

PubMed abstract

Research to Change Health Delivery Systems: On the Outside Looking in?

Of the more than $3.3 trillion dollars spent annually on health care in the USA, less than 0.1% currently goes towards research designed to improve how we deliver health care. Increasing the effectiveness and efficiency of health care delivery has implica...
Author(s): Gopalan A; Grant RW

J Gen Intern Med. 2018 Jul 20.

PubMed abstract

An Observational Study of Cardiovascular Risks Associated with Rheumatoid Arthritis Therapies: A Comparison of Two Analytical Approaches

Comparative safety studies typically use hierarchical treatment categories that lump monotherapy and combination therapy. The consequence of this approach on study results is not clear. For example, studies of tumor necrosis factor inhibitors usually lump...
Author(s): Herrinton LJ; Ray GT; Curtis JR; Wu JJ; Fireman B; Liu L; Goldfien R

Perm J. 2018 Jul 19;22.

PubMed abstract

Risk Adjustment for Hospital Characteristics Reduces Unexplained Hospital Variation in Pressure Injury Risk

Research investigating risk factors for hospital-acquired pressure injury (HAPI) has primarily focused on the characteristics of patients and nursing staff. Limited data are available on the association of hospital characteristics with HAPI. We aimed to q...
Author(s): Linnen DT; Kipnis P; Rondinelli J; Greene JD; Liu V; Escobar GJ

Nurs Res. 2018 Jul/Aug;67(4):314-323.

PubMed abstract

Toward the "Plateau of Productivity": Enhancing the Value of Machine Learning in Critical Care

Conventional wisdom suggests that we are climbing, or even cresting, the “peak of inflated expectations” when it comes to Big Data and machine learning. From this elevated perspective, the view is filled with the promise of peerless data and com...
Author(s): Liu VX

Crit Care Med. 2018 Jul;46(7):1196-1197.

PubMed abstract

Influence of a New Diabetes Diagnosis on the Health Behaviors of the Patient's Partner

When a person is given a diagnosis of diabetes, the changes in his or her health behaviors may influence the behaviors of his or her partner. The diabetes diagnosis may affect household members' perceptions of their own health risks, which could trigger b...
Author(s): Schmittdiel JA; Cunningham SA; Adams SR; Nielsen J; Ali MK

Ann Fam Med. 2018 Jul;16(4):290-295.

PubMed abstract

Brief Commentary: Glycemic Targets for Older Adults With Type 2 Diabetes

Most guidelines recommend individualizing glycemic targets for patients with type 2 diabetes in the context of shared decision making (1�4). In general; this strategy weighs the benefits of treatment against such factors as age; life expectancy; disease c...
Author(s): Schroeder EB; Karter AJ

Ann Intern Med. 2018 Jun 26.

PubMed abstract

Association of Initiation of Basal Insulin Analogs vs Neutral Protamine Hagedorn Insulin With Hypoglycemia-Related Emergency Department Visits or Hospital Admissions and With Glycemic Control in Patients With Type 2 Diabetes

In clinical trials of patients with type 2 diabetes, long-acting insulin analogs modestly reduced the risk of nocturnal hypoglycemia compared with human neutral protamine Hagedorn (NPH) insulin, but cost 2 to 10 times more. Outcomes in clinical practice m...
Author(s): Lipska KJ; Parker MM; Moffet HH; Huang ES; Karter AJ

JAMA. 2018 Jun 23.

PubMed abstract

Reducing risk of Clostridium difficile infection and overall use of antibiotic in the outpatient treatment of urinary tract infection

Risk of community-acquired Clostridium difficile infection (CA-CDI) following antibiotic treatment specifically for urinary tract infection (UTI) has not been evaluated. We conducted a nested case-control study at Kaiser Permanente Northern California, 20...
Author(s): Ge IY; Fevrier HB; Conell C; Kheraj MN; Flint AC; Smith DS; Herrinton LJ

Ther Adv Urol. 2018 Oct;10(10):283-293. Epub 2018-06-22.

PubMed abstract

Diabetes and Prediabetes Prevalence by Race and Ethnicity Among People With Severe Mental Illness

This is the first large cohort study examining laboratory-confirmed diabetes and prediabetes prevalence in a racially and ethnically diverse sample of antipsychotic-treated patients with SMI. Our lower (17.3%) and upper (28.1%) bound estimates of diabetes...
Author(s): Mangurian CV; Schillinger D; Newcomer JW; Vittinghoff E; Essock SM; Zhu Z; Dyer WT; Schmittdiel JA

Diabetes Care. 2018 07;41(7):e119-e120. Epub 2018-06-13.

PubMed abstract

Adherence to Cardio-protective Medications Prescribed for Secondary Prevention after an Acute Coronary Syndrome Hospitalization Compared to Usual Care

Secondary prevention after an acute coronary syndrome (ACS) hospitalization is critical to prevent additional morbidity and mortality. While poor adherence to prescribed cardio-protective medications is a known problem;1;2 it is unknown whether an ACS ...
Author(s): Rana JS; Parker MM; Liu JY; Moffet HH; Karter AJ

J Gen Intern Med. 2018 Jun 07.

PubMed abstract

Risk of Incident Atherosclerotic Cardiovascular Disease Events by Achieved Atherogenic Lipid Levels Among 62,428 Statin-Treated Individuals With Diabetes Mellitus

The relevance of low-density lipoprotein cholesterol (LDL-C) or non-high-density lipoprotein cholesterol (non-HDL-C) goals for primary prevention of atherosclerotic cardiovascular disease (ASCVD) among patients with diabetes was assessed. This retrospecti...
Author(s): Rana JS; Liu JY; Moffet HH; Boklage SH; Khan I; Karter AJ

Am J Cardiol. 2018 Jun 02.

PubMed abstract

Which Complex Patients Should Be Referred for Intensive Care Management? A Mixed-Methods Analysis

A large and increasing proportion of health care costs are spent caring for a small segment of medically and socially complex patients. To date, it has been difficult to identify which patients are best served by intensive care management. To characterize...
Author(s): Garcia ME; Uratsu CS; Sandoval-Perry J; Grant RW

J Gen Intern Med. 2018 May 24.

PubMed abstract

Surveillance of Hypoglycemia-Limitations of Emergency Department and Hospital Utilization Data

Author(s): Karter AJ; Moffet HH; Liu JY; Lipska KJ

JAMA Intern Med. 2018 Apr 16.

PubMed abstract

Association of Inflammatory Markers with Disease Progression in Patients with Metastatic Melanoma Treated with Immune Checkpoint Inhibitors

We investigated the effect of inflammatory biomarkers (neutrophil, platelet, and lymphocyte counts) on risk of progression in patients with metastatic melanoma treated with an immune checkpoint inhibitor targeting programmed cell death protein-1 (PD-1). T...
Author(s): Pan M; Alavi M; Herrinton LJ

Perm J. 2018 Mar 30;22.

PubMed abstract

Older adults' readiness to engage with eHealth patient education and self-care resources: a cross-sectional survey

This study examined access to digital technologies, skills and experience, and preferences for using web-based and other digital technologies to obtain health information and advice among older adults in a large health plan. A primary aim was to assess th...
Author(s): Gordon NP; Hornbrook MC

BMC Health Serv Res. 2018 03 27;18(1):220. Epub 2018-03-27.

PubMed abstract