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Health Care Delivery Publications


Response to Comment on Laiteerapong et al. The Legacy Effect in Type 2 Diabetes: Impact of Early Glycemic Control on Future Complications (The Diabetes & Aging Study). Diabetes Care 2019;42:XXXX-XXXX

Author(s): Laiteerapong N; Ham SA; Huang ES; Karter AJ

Diabetes Care. 2019 Jan 24.

PubMed abstract

Automated Early Detection of Obstetric Complications: Theoretical and Methodological Considerations

Compared to adults admitted to general medical-surgical wards, women admitted to labor and delivery services are at much lower risk of experiencing unexpected critical illness. Nonetheless, critical illness and other complications that put either the moth...
Author(s): Escobar GJ; Gupta NR; Walsh EM; Soltesz L; Terry SM; Kipnis P

Am J Obstet Gynecol. 2019 Jan 22.

PubMed abstract

Primary Care Physician Stress Driven by Social and Financial Needs of Complex Patients

Author(s): Weiner JZ; McCloskey JK; Uratsu CS; Grant RW

J Gen Intern Med. 2019 Jan 08.

PubMed abstract

Inpatient electronic health record maintenance from 2010 to 2015

To describe the scale and scope of inpatient electronic health record (EHR) maintenance following initial implementation. A retrospective study reviewing EHR change documentation within an integrated healthcare delivery system that has 21 hospitals. ...
Author(s): Liu VX; Haq N; Chan IC; Hoberman B

Am J Manag Care. 2019 Jan;25(1):18-21.

PubMed abstract

The health information technology special issue: new real-world evidence and practical lessons

As technology applications in healthcare continue to grow, electronic health records are maturing, interoperability is developing, and patient-facing technology use is expanding.
Author(s): Reed ME

Am J Manag Care. 2019 Jan;25(1):12.

PubMed abstract

Long-Term Outcomes Among Patients Discharged From the Hospital With Moderate Anemia: A Retrospective Cohort Study

Randomized clinical trial findings support decreased red blood cell (RBC) transfusion and short-term tolerance of in-hospital anemia. However, long-term outcomes related to changes in transfusion practice have not been described. To describe the prevalenc...
Author(s): Roubinian NH; Murphy EL; Mark DG; Triulzi DJ; Carson JL; Lee C; Kipnis P; Kleinman S; Liu VX; Escobar GJ

Ann Intern Med. 2018 Dec 18.

PubMed abstract

Tele-Triage Outcomes For Patients With Chest Pain: Comparing Physicians And Registered Nurses

We took advantage of a change in protocol in an integrated delivery system's telephone consultation service-routing callers complaining of chest pain to physicians instead of registered nurses, whenever feasible-to explore whether tele-triage outcomes dif...
Author(s): Sax DR; Vinson DR; Yamin CK; Huang J; Falck TM; Bhargava R; Amaral DJ; Reed ME

Health Aff (Millwood). 2018 Dec;37(12):1997-2004.

PubMed abstract

Real-Time Patient-Provider Video Telemedicine Integrated with Clinical Care

Author(s): Reed ME; Parikh R; Huang J; Ballard DW; Barr I; Wargon C

N Engl J Med. 2018 10 11;379(15):1478-1479.

PubMed abstract

Anti-TNF and Physiologic Measures of Metabolic Disease in Rheumatoid Arthritis

Author(s): Herrinton LJ; Ray GT; Wu JJ; Fireman B; Liu L; Goldfien R; Curtis JR

J Clin Rheumatol. 2018 Nov 07.

PubMed abstract

Exploring how patients understand and assess their diabetes control

Poor understanding of diabetes management targets is associated with worse disease outcomes. Patients may use different information than providers to assess their diabetes control. In this study, we identify the information patients use to gauge their cur...
Author(s): Gopalan A; Kellom K; McDonough K; Schapira MM

BMC Endocr Disord. 2018 Nov 06;18(1):79. Epub 2018-11-06.

PubMed abstract

Mobile-accessible personal health records increase the frequency and timeliness of PHR use for patients with diabetes

Personal health records (PHRs) offer patients a portal to view lab results, communicate with their doctors, and refill medications. Expanding PHR access to mobile devices could increase patients' engagement with their PHRs. We examined whether access to a...
Author(s): Graetz I; Huang J; Brand R; Hsu J; Reed ME

J Am Med Inform Assoc. 2018 Oct 24.

PubMed abstract

Understanding functional and social risk characteristics of frail older adults: a cross-sectional survey study

Frailty is a condition of increasing importance, given the aging adult population. With an anticipated shortage of geriatricians, primary care physicians will increasingly need to manage care for frail adults with complex functional risks and social-econo...
Author(s): Lee DR; Santo EC; Lo JC; Ritterman Weintraub ML; Patton M; Gordon NP

BMC Fam Pract. 2018 Oct 19;19(1):170. Epub 2018-10-19.

PubMed abstract

Using Neighborhood-Level Census Data to Predict Diabetes Progression in Patients with Laboratory-Defined Prediabetes

Research on predictors of clinical outcomes usually focuses on the impact of individual patient factors, despite known relationships between neighborhood environment and health. To determine whether US census information on where a patient resides is asso...
Author(s): Schmittdiel JA; Dyer WT; Marshall CJ; Bivins R

Perm J. 2018 Oct 05;22. Epub 2018-10-05.

PubMed abstract

Association of Medical Scribes in Primary Care With Physician Workflow and Patient Experience

Widespread adoption of electronic health records (EHRs) in medical care has resulted in increased physician documentation workload and decreased interaction with patients. Despite the increasing use of medical scribes for EHR documentation assistance, few...
Author(s): Mishra P; Kiang JC; Grant RW

JAMA Intern Med. 2018 Sep 17.

PubMed abstract

Association between Inhaled Corticosteroid Use and Pulmonary Nontuberculous Mycobacterial Infection

Nontuberculous mycobacterial (NTM) pulmonary disease prevalence is increasing. To determine the association between the use of inhaled corticosteroids (ICS) and the likelihood of NTM pulmonary infection among individuals with treated airways disease. We c...
Author(s): Liu VX; Winthrop KL; Lu Y; Sharifi H; Nasiri HU; Ruoss SJ

Ann Am Thorac Soc. 2018 Sep 14.

PubMed abstract

Prevalence and predictors of delayed clinical diagnosis of Type 2 diabetes: a longitudinal cohort study

To examine the prevalence and person-level predictors of undiagnosed Type 2 diabetes among adults with elevated HbA1c values. We identified adults without diabetes who had a first elevated HbA1c (index HbA1c ≥ 48 mmol/mol; ≥ 6.5%) between January 2014 and...
Author(s): Gopalan A; Mishra P; Alexeeff SE; Blatchins MA; Kim E; Man AH; Grant RW

Diabet Med. 2018 Sep 03.

PubMed abstract

The Legacy Effect in Type 2 Diabetes: Impact of Early Glycemic Control on Future Complications (the Diabetes & Aging Study)

To examine for a legacy effect of early glycemic control on diabetic complications and death. This cohort study of managed care patients with newly diagnosed type 2 diabetes and 10 years of survival (1997-2013, average follow-up 13.0 years, N = 34,737) ex...
Author(s): Laiteerapong N; Ham SA; Gao Y; Moffet HH; Liu JY; Huang ES; Karter AJ

Diabetes Care. 2018 Aug 13.

PubMed abstract

Research to Change Health Delivery Systems: On the Outside Looking in?

Of the more than $3.3 trillion dollars spent annually on health care in the USA, less than 0.1% currently goes towards research designed to improve how we deliver health care. Increasing the effectiveness and efficiency of health care delivery has implica...
Author(s): Gopalan A; Grant RW

J Gen Intern Med. 2018 Jul 20.

PubMed abstract

An Observational Study of Cardiovascular Risks Associated with Rheumatoid Arthritis Therapies: A Comparison of Two Analytical Approaches

Comparative safety studies typically use hierarchical treatment categories that lump monotherapy and combination therapy. The consequence of this approach on study results is not clear. For example, studies of tumor necrosis factor inhibitors usually lump...
Author(s): Herrinton LJ; Ray GT; Curtis JR; Wu JJ; Fireman B; Liu L; Goldfien R

Perm J. 2018 Jul 19;22.

PubMed abstract

Risk Adjustment for Hospital Characteristics Reduces Unexplained Hospital Variation in Pressure Injury Risk

Research investigating risk factors for hospital-acquired pressure injury (HAPI) has primarily focused on the characteristics of patients and nursing staff. Limited data are available on the association of hospital characteristics with HAPI. We aimed to q...
Author(s): Linnen DT; Kipnis P; Rondinelli J; Greene JD; Liu V; Escobar GJ

Nurs Res. 2018 Jul/Aug;67(4):314-323.

PubMed abstract

Toward the "Plateau of Productivity": Enhancing the Value of Machine Learning in Critical Care

Conventional wisdom suggests that we are climbing, or even cresting, the “peak of inflated expectations” when it comes to Big Data and machine learning. From this elevated perspective, the view is filled with the promise of peerless data and com...
Author(s): Liu VX

Crit Care Med. 2018 Jul;46(7):1196-1197.

PubMed abstract

Influence of a New Diabetes Diagnosis on the Health Behaviors of the Patient's Partner

When a person is given a diagnosis of diabetes, the changes in his or her health behaviors may influence the behaviors of his or her partner. The diabetes diagnosis may affect household members' perceptions of their own health risks, which could trigger b...
Author(s): Schmittdiel JA; Cunningham SA; Adams SR; Nielsen J; Ali MK

Ann Fam Med. 2018 Jul;16(4):290-295.

PubMed abstract

Brief Commentary: Glycemic Targets for Older Adults With Type 2 Diabetes

Most guidelines recommend individualizing glycemic targets for patients with type 2 diabetes in the context of shared decision making (1�4). In general; this strategy weighs the benefits of treatment against such factors as age; life expectancy; disease c...
Author(s): Schroeder EB; Karter AJ

Ann Intern Med. 2018 Jun 26.

PubMed abstract

Association of Initiation of Basal Insulin Analogs vs Neutral Protamine Hagedorn Insulin With Hypoglycemia-Related Emergency Department Visits or Hospital Admissions and With Glycemic Control in Patients With Type 2 Diabetes

In clinical trials of patients with type 2 diabetes, long-acting insulin analogs modestly reduced the risk of nocturnal hypoglycemia compared with human neutral protamine Hagedorn (NPH) insulin, but cost 2 to 10 times more. Outcomes in clinical practice m...
Author(s): Lipska KJ; Parker MM; Moffet HH; Huang ES; Karter AJ

JAMA. 2018 Jun 23.

PubMed abstract

Reducing risk of Clostridium difficile infection and overall use of antibiotic in the outpatient treatment of urinary tract infection

Risk of community-acquired Clostridium difficile infection (CA-CDI) following antibiotic treatment specifically for urinary tract infection (UTI) has not been evaluated. We conducted a nested case-control study at Kaiser Permanente Northern California, 20...
Author(s): Ge IY; Fevrier HB; Conell C; Kheraj MN; Flint AC; Smith DS; Herrinton LJ

Ther Adv Urol. 2018 Oct;10(10):283-293. Epub 2018-06-22.

PubMed abstract