This study will characterize and compare antecedents to hospitalization and in-hospital deterioration among patients with COVID-19 and comparator patients with influenza. We will quantify pre-existing comorbidities, medication adherence, and temporal fact...
Funder: AstraZeneca PLC
Investigator: Escobar, Gabriel
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This study will use electronic health record-derived patient data collected on adults newly diagnosed with type 2 diabetes from 2010-2015 and followed for 5 years to develop and validate machine-learning based predictive models to identify patients at inc...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Gopalan, Anjali
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The Delivery Science Rapid Analysis Program will create a mechanism to solicit, prioritize, and address rapidly researchable analytic questions with high value to TPMG's quality improvement initiatives and DOR's research agenda. The program will focus on ...
Funder: TPMG Delivery Science Projects Program
Investigator: Schmittdiel, Julie
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Examine the safety and effectiveness of current treatments for hospitalized patients with COVID-19 and identify patient characteristics and time periods during the disease course that are associated with more favorable treatment response.
Funder: Garfield Memorial Fund
Investigator: Liu, Vincent
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Educational attainment is an important social determinant of health, but it is not included in the electronic health records of a majority of adults. When the information is available, it is frequently not captured in a way that makes it easy to use in la...
Funder: Northern California Community Benefit Programs
Investigator: Gordon, Nancy
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This project aims to improve The Permanente Medical Group's capability for outpatient and population management of adults with COVID-19. It will identify the spatial, temporal, and racial distribution of coronavirus infections; characterize the clinical p...
Funder: TPMG Delivery Science Projects Program
Investigator: Escobar, Gabriel
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The goal of this study is to apply the patient-centered advance care planning paradigm of values elicitation and decision-making and communication preparation to hypoglycemia-related adverse outcomes in vulnerable older patients with type 2 diabetes. This...
Funder: National Institute on Aging
Investigator: Grant, Richard
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This study will conduct focus groups with KPNC members (age 45) with newly diagnosed Type 2 diabetes to learn about members’ experiences with this new diagnosis and to identify early facilitators of and barriers to effective diabetes management in this g...
Funder: Northern California Community Benefit Programs
Investigator: Gopalan, Anjali
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This study will gather data to estimate the prevalence of several different social and financial risk factors among adults aged 35-84 and assess whether risk factor prevalence significantly differs across age, race, health status, and income groups.
Funder: Northern California Community Benefit Programs
Investigator: Grant, Richard; Gordon, Nancy
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The study will examine patient knowledge and experience in a Value-based insurance designs plan by surveying 1,000 patients newly enrolling in a VBID plan. The survey will collect patient knowledge of their plan, patient-reported medication behavior (incl...
Funder: Northern California Community Benefit Programs
Investigator: Reed, Mary
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The COVID epidemic has exposed the fragility of the social network that supports our most complex and vulnerable members. We have established an interdisciplinary team of researchers, clinicians, and operational leaders at KPNC, KPCO, KPWA to study social...
Funder: Garfield Memorial Fund
Investigator: Grant, Richard
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The SRI team will (a) assess results of previous internal and external deployments of alternatives to hospitalization, (b) define strategies to quantify the potential pool of Kaiser Permanente Northern California patients who would be eligible for such al...
Funder: Kaiser Foundation Hospitals
Investigator: Escobar, Gabriel
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This pragmatic, randomized clinical trial will compare the effect of primary care physician academic detailing with or without patient pre-visit preparation on insulin de-prescribing rates among older patients with type 2 diabetes at high risk for insulin...
Funder: Patient-Centered Outcomes Research Institute
Investigator: Grant, Richard
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My team has been working collaboration with The Permanente Medical Group and Kaiser Foundation Health Plan to implement and evaluate care models to improve health outcomes of medically and socially complex patients. We are currently conducting a rapid cyc...
Funder: Kaiser Foundation Health Plan
Investigator: Grant, Richard
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The
goal of this research is to learn about use of digital information
technologies (DIT) and the kp.org website and patient portal, preferred
modalities for receiving health information and advice, and social
determinants of DIT use and health in...
Funder: Garfield Memorial Fund
Investigator: Gordon, Nancy
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This study will characterize type 1 and type 2 diabetes patients initiating newly prescribed continuous glucose monitors and evaluate the impact of that initiation on key clinical and utilization-based outcomes, and whether that impact differs across clin...
Funder: Dexcom
Investigator: Karter, Andrew
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Overall goal is to define and refine the current epidemiology, clinical characteristics, and treatment practices in respiratory failure in late and moderately preterm infants. Specific aims are to determine that incidence and epidemiology of respiratory f...
Funder: Moore Foundation
Investigator: Liu, Vincent
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The goals of this study are to (1) examine temporal trends in early hospital antibiotic prescribing patterns over the past 5 years, to assess for unintended consequences associated with earlier antibiotics in severe sepsis/septic shock; (2) quantify the p...
Funder: Agency for Healthcare Research and Quality
Investigator: Liu, Vincent
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The goal of this project is to assist with measure development and testing for the Hospital-Wide Mortality (HWM) hybrid and HWM claims-only measures. This includes providing consulting support to the Yale Center for Outcomes Research and Evaluation team a...
Funder: Centers for Medicare and Medicaid Services
Investigator: Escobar, Gabriel
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Aim 1: Identify patient-level predictors of metformin treatment during the year following type 2 diabetes diagnosis. Examined factors will include: demographics, such as age, race/ethnicity, gender, and rural versus urban; clinical characteristics, such a...
Funder: Northern California Community Benefit Programs
Investigator: Gopalan, Anjali
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This study will leverage the rich electronic data sources within Kaiser Permanente to create pragmatic tools for improving health and equity among primary care patients with the highest medical and social needs. Aim 1: Use advanced analytic methods to pre...
Funder: Agency for Healthcare Research and Quality
Investigator: Grant, Richard
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Medicare-age patients with type 2 diabetes are projected to double in the next 25 years and have high rates of complications and adverse drug events. However, older patients are largely excluded from the major clinical trials of diabetes care. This lack o...
Funder: National Institute on Aging
Investigator: Karter, Andrew
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There is an unmet clinical need to better understand the impact of lifestyle choices with respect to diet and nutrition in high-risk heart failure patients who have been recently hospitalized. We will conduct a survey-based project using a combination of ...
Funder: Northern California Community Benefit Programs
Investigator: Ambrosy, Andrew; Go, Alan; Gordon, Nancy
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Kaiser Permanente Northern California will participate with the FDA Sentinel to validate the diagnosis of health outcomes of interest.
Funder: U.S. Food and Drug Administration
Investigator: Herrinton, Lisa
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This project will examine patient and community-level correlates of housing instability and homelessness using observational data sources. These formative analyses will develop variables to operationalize housing instability using administrative and clini...
Funder: Northern California Community Benefit Programs
Investigator: Schmittdiel, Julie
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