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Health Care Delivery and Policy Studies

 

Trends in Diabetes Screening, Risk Factors and Incidence Before and After the SARS-CoV-2 Pandemic Between the California Medi-Cal and Commercially-Insured Populations

Using quasi-experimental research methods, this study is assessing the extent to which disparities in type 2 diabetes prevention and outcomes were exacerbated during the coronavirus disease 2019 (COVID-19) pandemic between the Medi-Cal and commercially-in...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Rodriguez, Luis

Post-acute sequelae of SARS-CoV-2 infection (PASC) in adult KPNC members

This study will establish a cohort of adult KPNC members with prior SARS-CoV-2 infection and identify those with a confirmed diagnosis of post-acute sequelae of SARS-CoV-2 infection to examine predictors, clinical care characteristics, and associated diag...
Funder: TPMG Delivery Science Projects Program
Investigator: Reed, Mary

Do health and health care indicators differ by preferred language in Latinx and Chinese Adults? A health and health care disparities study.

Limited English proficiency may be an important social determinant of health and health care access. This study will use electronic health record data to describe and compare health risks, chronic health conditions, quality metrics, and health care use by...
Funder: KP National Office of Community Health
Investigator: Gordon, Nancy

Predictive modeling of adverse mental health outcomes following acute hospitalizations for serious illness: A machine learning approach with natural language processing

This study addresses predicting risk of post-traumatic stress disorder and other mental health conditions following hospitalization for life-threatening conditions. We will use an existing, retrospective cohort of 408,377 patients hospitalized with sever...
Funder: Section Pilot Grants
Investigator: Papini, Santiago

Detection and Mitigation of Algorithmic Bias in Predictive Models of Suicide Risk

This project will assess the potential impact of algorithmic bias on the allocation of preventive care for suicide and compare the performance of methods designed to mitigate algorithmic bias.
Funder: Section Pilot Grants
Investigator: Papini, Santiago

A Social Needs Network for Evaluation and Translation (SONNET): Addressing the Social, Economic and Behavioral Needs of Kaiser Permanente Members

Social Needs Network for Evaluation and Translation (SONNET) is a national network of applied researchers who help design, evaluate, and implement effective social health interventions to improve member health across Kaiser Permanente. The SONNET Evaluat...
Funder: Kaiser Permanente Program Office
Investigator: Grant, Richard

Social Risk Screening and Social Risk Prediction: Research Consultation and Planning

Kaiser Permanente has set a national goal to increase social health screening among members. Dr. Grant and his DOR Complex Care Team will work with KP National Office of Community Health in a consultative role to address barriers and facilitators to socia...
Funder: KP National Office of Community Health
Investigator: Grant, Richard

Economic analysis of automated insulin delivery (AID) systems

Our aim is to determine if automated insulin delivery (AID) systems provide good value compared with standard insulin delivery. We will support the external validation of a computer simulation model (Swedish National Diabetes Register T1D model) which wil...
Funder: The Leona M. and Harry B. Helmsley Charitable Trust
Investigator: Karter, Andrew

Tailoring initial type 2 diabetes care to meet the needs of younger Latinx adults: A randomized pilot study

Our goal is to evaluate the effectiveness of a proactive, tailored care intervention in improving early outcomes for Latinx individuals with younger-onset type 2 diabetes. We will also conduct post-intervention interviews with study participants to identi...
Funder: American Diabetes Association
Investigator: Gopalan, Anjali

Social Risk Prediction Working Group

Our DOR Complex Care Team is working with Dr. Anand Shah and his team in a consultative role to address barriers and facilitators to social health screening. This work focuses on evaluating and implementing novel informatics-based strategies to guide memb...
Funder: Kaiser Permanente Program Office
Investigator: Grant, Richard

Comparative effectiveness of intermittently scanned continuous glucose monitors among patients with basal-bolus insulin-treated type 2 diabetes

This study will characterize patients selected by their providers for intermittently-scanned, continuous glucose monitor (isCGM) initiation and estimate the effect of isCGM initiation (relative to non-initiators) on clinical outcomes. We hypothesize that ...
Funder: TPMG Delivery Science Projects Program
Investigator: Karter, Andrew

Quantifying Racial/ethnic Differences in the Relationship Between Glucose Concentrations and Hemoglobin A1c

Physicians rely on hemoglobin A1c (A1C), an integrated measure of glycemia (blood glucose), to make treatment decisions for patients with diabetes. There is evidence that, given comparable glycemia, A1C results in African Americans can be significantly hi...
Funder: Northern California Community Benefit Programs
Investigator: Karter, Andrew

Turning back the clock on sepsis: Defining the epidemiology and opportunities of pre-sepsis

We intend to determine the epidemiology of pre-sepsis, including ambulatory and prehospital care settings, to identify modifiable care delays, opportunities for primary sepsis prevention, and to improve early sepsis care for vulnerable populations. The ob...
Funder: Gordon and Betty Moore Foundation
Investigator: Liu, Vincent

Evaluation of Risk-Based Predictive Models to Inform the Efficiency of Perioperative Systems

We previously developed an automated electronic health record-based risk stratification tool, called the Comorbidity Assessment and Surgical Triage (CAST) score, which we implemented in KP HealthConnect to improve triage of elective surgical patients to p...
Funder: TPMG Delivery Science Projects Program
Investigator: Liu, Vincent

Tailoring care to meet the needs of younger Latinx adults with newly diagnosed type 2 diabetes

We will evaluate a culturally responsive community health worker (CHW) intervention targeting younger-onset Latinx individuals with a new type 2 diabetes (T2D) diagnosis (AURORA [Active Outreach to Younger Latinx]). The AURORA strategy centers on a CHW wh...
Funder: Garfield Memorial Fund
Investigator: Gopalan, Anjali

Women’s Multi-Ethnic Health and Lifestyle Survey

We propose to survey White, Black, Latina, Filipina, Chinese, South Asian, Vietnamese, and Japanese women aged 35-79 to characterize and compare these racial/ethnic groups on behaviors and risks related to 7 lifestyle medicine domains (diet, physical acti...
Funder: Northern California Community Benefit Programs
Investigator: Gordon, Nancy

Barriers and Facilitators to TracFone/CareLink Implementation in Two Kaiser Permanente Regions

This study will evaluate TracFone/CareLink program within Kaiser Permanente (KP) Digital Health Equity portfolio. It will involve engaging local leaders, end users, and KP members in the planning, implementation, and initial assessment of barriers and fac...
Funder: Northern California Community Benefit Programs
Investigator: Grant, Richard

A Pragmatic Randomized Controlled Trial of a Bundled, Pharmacist-Led Hyperpolypharmacy Deprescribing Intervention

This randomized controlled trial study is testing an intervention to reduce unsafe medication use in patients aged 75 years and older. The intervention uses collaborative drug therapy management between physicians and pharmacists, standard-of-care treatme...
Funder: TPMG Delivery Science Projects Program
Investigator: Herrinton, Lisa

Diabetes Research for Equity through Advanced Multilevel Science Center for Diabetes Translational Research (DREAMS-CDTR)

The Diabetes Research for Equity through Advanced Multilevel Science Center for Diabetes Translational Research(DREAMS-CDTR) supports diabetes translational research through mentoring and supporting junior faculty, and by fostering collaborations between ...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Schmittdiel, Julie

Using predictive analytics to tailor care for patients with newly diagnosed type 2 diabetes

In a population of adults newly diagnosed with type 2 diabetes (T2D) from 2010-2015 and followed for 5 years this study will use machine learning-based predictive analytic methods to develop and validate predictive models using EHR-derived patient data av...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Gopalan, Anjali

The Delivery Science Targeted Analysis Program: A Partnership between the Division of Research and The Permanente Medical Group-Project 3

The Delivery Science Rapid Analysis Program will create a mechanism to solicit, prioritize, and address rapidly researchable analytic questions with high value to TPMG's quality improvement initiatives and DOR's research agenda. The program will focus on ...
Funder: TPMG Delivery Science Projects Program
Investigator: Schmittdiel, Julie

Effectiveness and safety of treatments for hospitalized patients with COVID-19

Examine the safety and effectiveness of current treatments for hospitalized patients with COVID-19 and identify patient characteristics and time periods during the disease course that are associated with more favorable treatment response.
Funder: Garfield Memorial Fund
Investigator: Liu, Vincent

Building an Evidence Case for Capturing Educational Attainment in the EHR as a Social Determinant of Health

Educational attainment is an important social determinant of health, but it is not included in the electronic health records of a majority of adults. When the information is available, it is frequently not captured in a way that makes it easy to use in la...
Funder: Northern California Community Benefit Programs
Investigator: Gordon, Nancy

Clinical Trial of Expanded Advance Care Planning to Address Regimen Intensity in Older Patients at High Risk for Treatment-Induced Hypoglycemia

The goal of this study is to apply the patient-centered advance care planning paradigm of values elicitation and decision-making and communication preparation to hypoglycemia-related adverse outcomes in vulnerable older patients with type 2 diabetes. This...
Funder: National Institute on Aging
Investigator: Grant, Richard

Age- and race/ethnic-based disparities in diabetes outcomes among younger adults with newly diagnosed Type 2 Diabetes

This study will conduct focus groups with KPNC members (age 45) with newly diagnosed Type 2 diabetes to learn about members’ experiences with this new diagnosis and to identify early facilitators of and barriers to effective diabetes management in this g...
Funder: Northern California Community Benefit Programs
Investigator: Gopalan, Anjali
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