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Health Care Delivery and Policy Studies

 

A Social Needs Network for Evaluation and Translation (SONNET): Addressing the Social, Economic and Behavioral Needs of Kaiser Permanente Members

Social Needs Network for Evaluation and Translation (SONNET) is a national network of applied researchers who help design, evaluate, and implement effective social health interventions to improve member health across Kaiser Permanente. The SONNET Evaluat...
Funder: Kaiser Permanente Program Office
Investigator: Grant, Richard

Social Risk Screening and Social Risk Prediction: Research Consultation and Planning

Kaiser Permanente has set a national goal to increase social health screening among members. Dr. Grant and his DOR Complex Care Team will work with KP National Office of Community Health in a consultative role to address barriers and facilitators to soci...
Funder: 
Investigator: Grant, Richard

Economic analysis of automated insulin delivery (AID) systems

Our aim is to determine if automated insulin delivery (AID) systems provide good value compared with standard insulin delivery. We will support the external validation of a computer simulation model (Swedish National Diabetes Register T1D model) which wil...
Funder: 
Investigator: Karter, Andrew

Tailoring initial type 2 diabetes care to meet the needs of younger Latinx adults: A randomized pilot study

Our goal is to evaluate the effectiveness of a proactive, tailored care intervention in improving early outcomes for Latinx individuals with younger-onset type 2 diabetes. We will also conduct post-intervention interviews with study participants to identi...
Funder: American Diabetes Association
Investigator: Gopalan, Anjali

Social Risk Prediction Working Group

Our DOR Complex Care Team is working with Dr. Anand Shah and his team in a consultative role to address barriers and facilitators to social health screening. This work focuses on evaluating and implementing novel informatics-based strategies to guide memb...
Funder: Kaiser Permanente Program Office
Investigator: Grant, Richard

Comparative effectiveness of intermittently scanned continuous glucose monitors among patients with basal-bolus insulin-treated type 2 diabetes

This study will characterize patients selected by their providers for intermittently-scanned, continuous glucose monitor (isCGM) initiation and estimate the effect of isCGM initiation (relative to non-initiators) on clinical outcomes. We hypothesize that ...
Funder: TPMG Delivery Science Projects Program
Investigator: Karter, Andrew

Quantifying Racial/ethnic Differences in the Relationship Between Glucose Concentrations and Hemoglobin A1c

Physicians rely on hemoglobin A1c (A1C), an integrated measure of glycemia (blood glucose), to make treatment decisions for patients with diabetes. There is evidence that, given comparable glycemia, A1C results in African Americans can be significantly hi...
Funder: Northern California Community Benefit Programs
Investigator: Karter, Andrew

Turning back the clock on sepsis: Defining the epidemiology and opportunities of pre-sepsis

We intend to determine the epidemiology of pre-sepsis, including ambulatory and prehospital care settings, to identify modifiable care delays, opportunities for primary sepsis prevention, and to improve early sepsis care for vulnerable populations. The ob...
Funder: Gordon and Betty Moore Foundation
Investigator: Liu, Vincent

Evaluation of Risk-Based Predictive Models to Inform the Efficiency of Perioperative Systems

We previously developed an automated electronic health record-based risk stratification tool, called the Comorbidity Assessment and Surgical Triage (CAST) score, which we implemented in KP HealthConnect to improve triage of elective surgical patients to p...
Funder: TPMG Delivery Science Projects Program
Investigator: Liu, Vincent

Tailoring care to meet the needs of younger Latinx adults with newly diagnosed type 2 diabetes

We will evaluate a culturally responsive community health worker (CHW) intervention targeting younger-onset Latinx individuals with a new type 2 diabetes (T2D) diagnosis (AURORA [Active Outreach to Younger Latinx]). The AURORA strategy centers on a CHW wh...
Funder: Garfield Memorial Fund
Investigator: Gopalan, Anjali

Women’s Multi-Ethnic Health and Lifestyle Survey

We propose to survey White, Black, Latina, Filipina, Chinese, South Asian, Vietnamese, and Japanese women aged 35-79 to characterize and compare these racial/ethnic groups on behaviors and risks related to 7 lifestyle medicine domains (diet, physical acti...
Funder: Northern California Community Benefit Programs
Investigator: Gordon, Nancy

Barriers and Facilitators to TracFone/CareLink Implementation in Two Kaiser Permanente Regions

This study will evaluate TracFone/CareLink program within Kaiser Permanente (KP) Digital Health Equity portfolio. It will involve engaging local leaders, end users, and KP members in the planning, implementation, and initial assessment of barriers and fac...
Funder: Northern California Community Benefit Programs
Investigator: Grant, Richard

A Pragmatic Randomized Controlled Trial of a Bundled, Pharmacist-Led Hyperpolypharmacy Deprescribing Intervention

This randomized controlled trial study is testing an intervention to reduce unsafe medication use in patients aged 75 years and older. The intervention uses collaborative drug therapy management between physicians and pharmacists, standard-of-care treatme...
Funder: TPMG Delivery Science Projects Program
Investigator: Herrinton, Lisa

Diabetes Research for Equity through Advanced Multilevel Science Center for Diabetes Translational Research (DREAMS-CDTR)

The Diabetes Research for Equity through Advanced Multilevel Science Center for Diabetes Translational Research(DREAMS-CDTR) supports diabetes translational research through mentoring and supporting junior faculty, and by fostering collaborations between ...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Schmittdiel, Julie

COVID-19: Antecedents to Hospitalization and Deterioration

This study will characterize and compare antecedents to hospitalization and in-hospital deterioration among patients with COVID-19 and comparator patients with influenza. We will quantify pre-existing comorbidities, medication adherence, and temporal fact...
Funder: AstraZeneca PLC
Investigator: Escobar, Gabriel

Using predictive analytics to tailor care for patients with newly diagnosed type 2 diabetes

In a population of adults newly diagnosed with type 2 diabetes (T2D) from 2010-2015 and followed for 5 years this study will use machine learning-based predictive analytic methods to develop and validate predictive models using EHR-derived patient data av...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Gopalan, Anjali

The Delivery Science Targeted Analysis Program: A Partnership between the Division of Research and The Permanente Medical Group-Project 3

The Delivery Science Rapid Analysis Program will create a mechanism to solicit, prioritize, and address rapidly researchable analytic questions with high value to TPMG's quality improvement initiatives and DOR's research agenda. The program will focus on ...
Funder: TPMG Delivery Science Projects Program
Investigator: Schmittdiel, Julie

Effectiveness and safety of treatments for hospitalized patients with COVID-19

Examine the safety and effectiveness of current treatments for hospitalized patients with COVID-19 and identify patient characteristics and time periods during the disease course that are associated with more favorable treatment response.
Funder: Garfield Memorial Fund
Investigator: Liu, Vincent

Building an Evidence Case for Capturing Educational Attainment in the EHR as a Social Determinant of Health

Educational attainment is an important social determinant of health, but it is not included in the electronic health records of a majority of adults. When the information is available, it is frequently not captured in a way that makes it easy to use in la...
Funder: Northern California Community Benefit Programs
Investigator: Gordon, Nancy

Tools for Outpatient and Population Management of SARS-COV-2 Infection (TOPS2)

This project aims to improve The Permanente Medical Group's capability for outpatient and population management of adults with COVID-19. It will identify the spatial, temporal, and racial distribution of coronavirus infections; characterize the clinical p...
Funder: TPMG Delivery Science Projects Program
Investigator: Escobar, Gabriel

Clinical Trial of Expanded Advance Care Planning to Address Regimen Intensity in Older Patients at High Risk for Treatment-Induced Hypoglycemia

The goal of this study is to apply the patient-centered advance care planning paradigm of values elicitation and decision-making and communication preparation to hypoglycemia-related adverse outcomes in vulnerable older patients with type 2 diabetes. This...
Funder: National Institute on Aging
Investigator: Grant, Richard

Age- and race/ethnic-based disparities in diabetes outcomes among younger adults with newly diagnosed Type 2 Diabetes

This study will conduct focus groups with KPNC members (age 45) with newly diagnosed Type 2 diabetes to learn about members’ experiences with this new diagnosis and to identify early facilitators of and barriers to effective diabetes management in this g...
Funder: Northern California Community Benefit Programs
Investigator: Gopalan, Anjali

Prevalence of Social Risks and Association of Social Risks with Health and Well-Being Among Non-Safety Net Middle-Aged and Older Adult Members in Kaiser Permanente Northern California

This study will gather data to estimate the prevalence of several different social and financial risk factors among adults aged 35-84 and assess whether risk factor prevalence significantly differs across age, race, health status, and income groups.
Funder: Northern California Community Benefit Programs
Investigator: Grant, Richard; Gordon, Nancy

Patient experiences with Value-Based Insurance Designs (VBID) in Kaiser Permanente: Plan Knowledge and Medication Behavior

The study will examine patient knowledge and experience in a Value-based insurance designs plan by surveying 1,000 patients newly enrolling in a VBID plan. The survey will collect patient knowledge of their plan, patient-reported medication behavior (incl...
Funder: Northern California Community Benefit Programs
Investigator: Reed, Mary

Impact of the COVID Pandemic on KP Members with Complex Medical and Social Needs

The COVID epidemic has exposed the fragility of the social network that supports our most complex and vulnerable members. We have established an interdisciplinary team of researchers, clinicians, and operational leaders at KPNC, KPCO, KPWA to study social...
Funder: Garfield Memorial Fund
Investigator: Grant, Richard
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