The
goal of this research ...
Funder: Garfield Memorial Fund
Investigator: Gordon, Nancy
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This study will characterize type 1 and type 2 diabetes patients initiating newly prescribed continuous glucose monitors and evaluate the impact of that initiation on key clinical and utilization-based outcomes, and whether that impact differs across clin...
Funder: Dexcom
Investigator: Karter, Andrew
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Overall goal is to define and refine the current epidemiology, clinical characteristics, and treatment practices in respiratory failure in late and moderately preterm infants. Specific aims are to determine that incidence and epidemiology of respiratory f...
Funder: Moore Foundation
Investigator: Liu, Vincent
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The goals of this study are to (1) examine temporal trends in early hospital antibiotic prescribing patterns over the past 5 years, to assess for unintended consequences associated with earlier antibiotics in severe sepsis/septic shock; (2) quantify the p...
Funder: Agency for Healthcare Research and Quality
Investigator: Liu, Vincent
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The goal of this project is to assist with measure development and testing for the Hospital-Wide Mortality (HWM) hybrid and HWM claims-only measures. This includes providing consulting support to the Yale Center for Outcomes Research and Evaluation team a...
Funder: Centers for Medicare and Medicaid Services
Investigator: Escobar, Gabriel
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Aim 1: Identify patient-level predictors of metformin treatment during the year following type 2 diabetes diagnosis. Examined factors will include: demographics, such as age, race/ethnicity, gender, and rural versus urban; clinical characteristics...
Funder: Northern California Community Benefit Programs
Investigator: Gopalan, Anjali
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This study will leverage the rich electronic data sources within Kaiser Permanente to create pragmatic tools for improving health and equity among primary care patients with the highest medical and social needs. Aim 1: Use advanced analytic methods to...
Funder: Agency for Healthcare Research and Quality
Investigator: Grant, Richard
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Medicare-age patients with type 2 diabetes are projected to double in the next 25 years and have high rates of complications and adverse drug events. However, older patients are largely excluded from the major clinical trials of diabetes care. This lack o...
Funder: National Institute on Aging
Investigator: Karter, Andrew
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Kaiser Permanente Northern California will participate with the FDA Sentinel to validate the diagnosis of health outcomes of interest.
Funder: U.S. Food and Drug Administration
Investigator: Herrinton, Lisa
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This project will examine patient and community-level correlates of housing instability and homelessness using observational data sources. These formative analyses will develop variables to operationalize housing instability using administrative and clini...
Funder: Northern California Community Benefit Programs
Investigator: Schmittdiel, Julie
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The benefit of teledermatology for triaging skin rashes is not adequately understood. The study will assess how implementation of teledermatology (technology and staffing) improves the effectiveness and efficiency of diagnosis, including wait time to diag...
Funder: The Permanente Medical Group
Investigator: Herrinton, Lisa
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Sepsis is the most common illness leading to hospitalization in the United States, affecting more than 1 million Americans each year. While short-term mortality has improved over prior decades, sepsis survivors face numerous post-hospital sequelae that ne...
Funder: National Heart, Lung, and Blood Institute
Investigator: Liu, Vincent
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Rapid expansions in the use of electronic health record (EHR) systems also contribute to large expansions in the availability of metadata. These highly granular metadata may prove particularly useful for understanding how frontline clinicians interact wit...
Funder: Gordon and Betty Moore Foundation
Investigator: Liu, Vincent
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Conducted with co-investigator Dustin G. Mark, MD, this study helps emergency physicians with estimates of individual patient risk for patients with chest pain. The research team will evaluate impacts on guideline-supported acute coronary syndrome evaluat...
Funder: The Permanente Medical Group
Investigator: Reed, Mary
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This project aims to develop a set of algorithms for generic error detection, prevention, and mitigation in the hospital setting. The goal is to develop algorithms that can operate in real time so as to support an existing infrastructure (the eHospita...
Funder: Kaiser Foundation Hospitals
Investigator: Escobar, Gabriel
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In a population of adults with newly diagnosed, early onset type 2 diabetes, this study will identify patient-, provider-, and system-level predictors of inadequate glycemic control within one year following diagnosis. A longitudinal, retrospective co...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Gopalan, Anjali
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This study will examine whether significant differences across Asian ethnic groups in prevalence of chronic diseases, behavioral/psychosocial risk factors, preventive service use, and patient portal use are masked when statistics are reported for “Asi...
Funder: Northern California Community Benefit Programs
Investigator: Gordon, Nancy
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A relatively small proportion of patients with complex needs represent a major source of cost and utilization. The fundamental principle that distinguishes complex needs patients from other high-cost patients with well-defined medical issues is that &...
Funder: Garfield Memorial Fund
Investigator: Grant, Richard
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Diabetes remains a leading cause of morbidity and mortality, and it is a significant burden to the U.S. health care system, patients, and their families. The knowledge and skills necessary to overcome the final translational block from evidence into pract...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Grant, Richard; Schmittdiel, Julie
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This administrative supplement solicited by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) will provide two to six medical students with summer training opportunities in translational research. This supplement allows the exis...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Grant, Richard; Schmittdiel, Julie
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The clinical and financial impact of diabetes-related interventions and policies may not be quantifiable without the use of simulation models that reflect the long-term course of disease and its complications. Models of diabetes complications are used...
Funder: National Institute on Minority Health and Health Disparities
Investigator: Karter, Andrew
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This project is designed to pursue pre-sepsis opportunities to identify patients at high-risk for sepsis and develop risk prediction models to mitigate the impact of impending sepsis by leveraging granular electronic health record data.
Funder: National Institute of General Medical Sciences
Investigator: Liu, Vincent
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