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Health Care Delivery and Policy Studies

 

Tailoring care to meet the needs of younger Latinx adults with newly diagnosed type 2 diabetes

We will evaluate a culturally responsive community health worker (CHW) intervention targeting younger-onset Latinx individuals with a new type 2 diabetes (T2D) diagnosis (AURORA [Active Outreach to Younger Latinx]). The AURORA strategy centers on a CHW wh...
Funder: Garfield Memorial Fund
Investigator: Gopalan, Anjali

Women’s Multi-Ethnic Health and Lifestyle Survey

White, Black, Latina, and Asian women aged 35-79 will be surveyed to characterize and compare these racial/ethnic groups on behaviors and risks related to 7 lifestyle medicine domains (diet, physical activity, sleep, stress management, tobacco avoidance, ...
Funder: Northern California Community Benefit Programs
Investigator: Gordon, Nancy

Barriers and Facilitators to TracFone/CareLink Implementation in Two Kaiser Permanente Regions

This study will evaluate TracFone/CareLink program within Kaiser Permanente (KP) Digital Health Equity portfolio. It will involve engaging local leaders, end users, and KP members in the planning, implementation, and initial assessment of barriers and fac...
Funder: Northern California Community Benefit Programs
Investigator: Grant, Richard

A Pragmatic Randomized Controlled Trial of a Bundled, Pharmacist-Led Hyperpolypharmacy Deprescribing Intervention

This randomized controlled trial study is testing an intervention to reduce unsafe medication use in patients aged 75 years and older. The intervention uses collaborative drug therapy management between physicians and pharmacists, standard-of-care treatme...
Funder: TPMG Delivery Science Projects Program
Investigator: Herrinton, Lisa

Diabetes Research for Equity through Advanced Multilevel Science Center for Diabetes Translational Research (DREAMS-CDTR)

The Diabetes Research for Equity through Advanced Multilevel Science Center for Diabetes Translational Research(DREAMS-CDTR) supports diabetes translational research through mentoring and supporting junior faculty, and by fostering collaborations between ...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Schmittdiel, Julie

COVID-19: Antecedents to Hospitalization and Deterioration

This study will characterize and compare antecedents to hospitalization and in-hospital deterioration among patients with COVID-19 and comparator patients with influenza. We will quantify pre-existing comorbidities, medication adherence, and temporal fact...
Funder: AstraZeneca PLC
Investigator: Escobar, Gabriel

Using predictive analytics to tailor care for patients with newly diagnosed type 2 diabetes

In a population of adults newly diagnosed with type 2 diabetes (T2D) from 2010-2015 and followed for 5 years this study will use machine learning-based predictive analytic methods to develop and validate predictive models using EHR-derived patient data av...
Funder: National Institute of Diabetes and Digestive and Kidney Diseases
Investigator: Gopalan, Anjali

The Delivery Science Targeted Analysis Program: A Partnership between the Division of Research and The Permanente Medical Group-Project 3

The Delivery Science Rapid Analysis Program will create a mechanism to solicit, prioritize, and address rapidly researchable analytic questions with high value to TPMG's quality improvement initiatives and DOR's research agenda. The program will focus on ...
Funder: TPMG Delivery Science Projects Program
Investigator: Schmittdiel, Julie

Effectiveness and safety of treatments for hospitalized patients with COVID-19

Examine the safety and effectiveness of current treatments for hospitalized patients with COVID-19 and identify patient characteristics and time periods during the disease course that are associated with more favorable treatment response.
Funder: Garfield Memorial Fund
Investigator: Liu, Vincent

Building an Evidence Case for Capturing Educational Attainment in the EHR as a Social Determinant of Health

Educational attainment is an important social determinant of health, but it is not included in the electronic health records of a majority of adults. When the information is available, it is frequently not captured in a way that makes it easy to use in la...
Funder: Northern California Community Benefit Programs
Investigator: Gordon, Nancy

Tools for Outpatient and Population Management of SARS-COV-2 Infection (TOPS2)

This project aims to improve The Permanente Medical Group's capability for outpatient and population management of adults with COVID-19. It will identify the spatial, temporal, and racial distribution of coronavirus infections; characterize the clinical p...
Funder: TPMG Delivery Science Projects Program
Investigator: Escobar, Gabriel

Clinical Trial of Expanded Advance Care Planning to Address Regimen Intensity in Older Patients at High Risk for Treatment-Induced Hypoglycemia

The goal of this study is to apply the patient-centered advance care planning paradigm of values elicitation and decision-making and communication preparation to hypoglycemia-related adverse outcomes in vulnerable older patients with type 2 diabetes. This...
Funder: National Institute on Aging
Investigator: Grant, Richard

Age- and race/ethnic-based disparities in diabetes outcomes among younger adults with newly diagnosed Type 2 Diabetes

This study will conduct focus groups with KPNC members (age 45) with newly diagnosed Type 2 diabetes to learn about members’ experiences with this new diagnosis and to identify early facilitators of and barriers to effective diabetes management in this g...
Funder: Northern California Community Benefit Programs
Investigator: Gopalan, Anjali

Prevalence of Social Risks and Association of Social Risks with Health and Well-Being Among Non-Safety Net Middle-Aged and Older Adult Members in Kaiser Permanente Northern California

This study will gather data to estimate the prevalence of several different social and financial risk factors among adults aged 35-84 and assess whether risk factor prevalence significantly differs across age, race, health status, and income groups.
Funder: Northern California Community Benefit Programs
Investigator: Grant, Richard; Gordon, Nancy

Patient experiences with Value-Based Insurance Designs (VBID) in Kaiser Permanente: Plan Knowledge and Medication Behavior

The study will examine patient knowledge and experience in a Value-based insurance designs plan by surveying 1,000 patients newly enrolling in a VBID plan. The survey will collect patient knowledge of their plan, patient-reported medication behavior (incl...
Funder: Northern California Community Benefit Programs
Investigator: Reed, Mary

Impact of the COVID Pandemic on KP Members with Complex Medical and Social Needs

The COVID epidemic has exposed the fragility of the social network that supports our most complex and vulnerable members. We have established an interdisciplinary team of researchers, clinicians, and operational leaders at KPNC, KPCO, KPWA to study social...
Funder: Garfield Memorial Fund
Investigator: Grant, Richard

Hospital Alternatives (HALT)

The SRI team will (a) assess results of previous internal and external deployments of alternatives to hospitalization, (b) define strategies to quantify the potential pool of Kaiser Permanente Northern California patients who would be eligible for such al...
Funder: Kaiser Foundation Hospitals
Investigator: Escobar, Gabriel

Reducing Treatment Risk in Older Patients with Diabetes: Comparative Effectiveness of Academic Detailing with and without Pre-Visit Patient Preparation

This pragmatic, randomized clinical trial will compare the effect of primary care physician academic detailing with or without patient pre-visit preparation on insulin de-prescribing rates among older patients with type 2 diabetes at high risk for insulin...
Funder: Patient-Centered Outcomes Research Institute
Investigator: Grant, Richard

Complex Patients: DOR Research Team

My team has been working collaboration with The Permanente Medical Group and Kaiser Foundation Health Plan to implement and evaluate care models to improve health outcomes of medically and socially complex patients. We are currently conducting a rapid cyc...
Funder: Kaiser Foundation Health Plan
Investigator: Grant, Richard

Use of Digital Information Technologies and Health Information Resources by Limited English Proficient Latino and Chinese Adult Members

The goal of this research is to learn about use of digital information technologies (DIT) and the kp.org website and patient portal, preferred modalities for receiving health information and advice, and social determinants of DIT use and health in...
Funder: Garfield Memorial Fund
Investigator: Gordon, Nancy

Comparative Effectiveness of Real-Time Continuous Glucose Monitoring (CGM) Among Insulin-Treated Diabetes Patients from Kaiser Permanente Northern California

This study will characterize type 1 and type 2 diabetes patients initiating newly prescribed continuous glucose monitors and evaluate the impact of that initiation on key clinical and utilization-based outcomes, and whether that impact differs across clin...
Funder: Dexcom
Investigator: Karter, Andrew

Sepsis on FHIR

Overall goal is to define and refine the current epidemiology, clinical characteristics, and treatment practices in respiratory failure in late and moderately preterm infants. Specific aims are to determine that incidence and epidemiology of respiratory f...
Funder: Moore Foundation
Investigator: Liu, Vincent

Understanding and Informing Early Hospital Antibiotic Prescribing for Potential Infection

The goals of this study are to (1) examine temporal trends in early hospital antibiotic prescribing patterns over the past 5 years, to assess for unintended consequences associated with earlier antibiotics in severe sepsis/septic shock; (2) quantify the p...
Funder: Agency for Healthcare Research and Quality
Investigator: Liu, Vincent

Development, Reevaluation, and Implementation of Outcome/Efficiency Measures for Hospital and Eligible Clinicians

The goal of this project is to assist with measure development and testing for the Hospital-Wide Mortality (HWM) hybrid and HWM claims-only measures. This includes providing consulting support to the Yale Center for Outcomes Research and Evaluation team a...
Funder: Centers for Medicare and Medicaid Services
Investigator: Escobar, Gabriel

Metformin Initiation and Early Adherence among Kaiser Permanente Northern California Members with Newly Diagnosed Type 2 Diabetes

Aim 1: Identify patient-level predictors of metformin treatment during the year following type 2 diabetes diagnosis. Examined factors will include: demographics, such as age, race/ethnicity, gender, and rural versus urban; clinical characteristics, such a...
Funder: Northern California Community Benefit Programs
Investigator: Gopalan, Anjali
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