skip to Main Content

A study of HPV typing for the management of HPV-positive ASC-US cervical cytologic results

In US cervical screening, immediate colposcopy is recommended for women with HPV-positive ASC-US (equivocal) cytology. We evaluated whether partial typing by Onclarity ™ (BD) might identify HPV-positive women with low enough CIN3+ risk to permit 1-year follow-up instead. The NCI-Kaiser Permanente Northern California Persistence and Progression cohort includes a subset of 13,890 women aged 21+ with HC2 (Qiagen)-positive ASC-US at enrollment; current median follow-up is 3.0years. Using stratified random sampling, we typed 2079 archived enrollment specimens including 329 women subsequently diagnosed with CIN3+, 563 with CIN2, and 1187 with

Authors: Schiffman M; Vaughan LM; Raine-Bennett TR; Castle PE; Katki HA; Gage JC; Fetterman B; Befano B; Wentzensen N

Gynecol Oncol. 2015 Sep;138(3):573-8. Epub 2015-07-04.

PubMed abstract

Explore all studies and publications

Back To Top