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Early Adopters of Event-driven Human Immunodeficiency Virus Pre-exposure Prophylaxis in a Large Healthcare System in San Francisco

Among 279 patients within a large healthcare system in San Francisco, event-driven HIV pre-exposure prophylaxis using a 2-1-1 regimen was a desirable alternative to daily dosing. Problems with adherence, planning sex in advance, or side effects were infrequent (13.9%). We found no new HIV infections over 136 person-years of follow-up.

Authors: Hojilla JC; Marcus JL; Silverberg MJ; Hare CB; Herbers R; Hurley L; Satre DD; Volk JE

Clin Infect Dis. 2020 12 17;71(10):2710-2712.

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