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HIV-1 drug resistance genotype results in patients with plasma samples with HIV-1 RNA levels less than 75 copies/mL

HIV-1 genotypic resistance test results were obtained on clinical samples from 116 patients with plasma HIV-1 RNA levels of less than 75 copies/mL. Genotype validity was confirmed in 49 of 50 patients with a previous or follow-up genotype. The belief that genotypic resistance testing is unreliable in samples with low-level viremia should be reassessed.

Authors: Mitsuya Y; Winters MA; Fessel WJ; Rhee SY; Slome S; Flamm J; Horberg M; Hurley L; Klein D; Shafer RW

J Acquir Immune Defic Syndr. 2006 Sep;43(1):56-9.

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