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Determining the modifying role of prenatal depression on the association between gestational diabetes mellitus and early childhood obesity

This study will explore the potential modifying (i.e., synergistic) impact of prenatal depression on the association between gestational diabetes mellitus (GDM) and childhood weight trajectories, as well as the risk of childhood obesity across various life stages. We hypothesize that a synergistic effect will occur in children born to mothers who experienced both GDM and prenatal depression during pregnancy, resulting in a more pronounced upward trajectory in childhood BMI and an increased likelihood of obesity at each life stage. We anticipate that the offspring of women facing both conditions will display accelerated weight gain and a higher risk of obesity at each life stage compared to those born to women who had only one or neither of these conditions during pregnancy.

Investigator: Peterson, Alicia

Funder: Northern California Community Benefit Programs

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