Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in a Multiethnic Cohort of Oldest-Old – DUPLICATED DO NOT ACTIVATE

This study is following a diverse cohort of approximately 1,000 KPNC members over 90 years old to examine life-course risk and protective factors of healthy brain aging in order to 1) Evaluate differences in dementia incidence and rate of cognitive decline by race/ethnicity; 2) evaluate how early life experience and life-course health are related to dementia incidence and cognitive decline while accounting for selective survival; and 3) examine life-course factors associated with biomarkers from braining imaging and pathology. During this second funding cycle, we will enroll 500 additional KPNC members at least 90 years old.

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