Extension of the Consortium to improve OutcoMes in HIV/Aids, Alcohol, Aging & multi-Substance (COMpAAAS)

With support from the National Institute on Alcohol Abuse and Alcoholism, the Consortium to improve OutcoMes in HIV/Aids, Alcohol, Aging & multi-Substance (COMpAAAS) has analyzed data from patients in the Veterans Administration Cohort Study. This project seeks to extend this consortium to include Kaiser Permanente and the antiretroviral therapy cohort collaboration at the University of Bristol as new partners to increase sample diversity and representation of people living with HIV. The primary goals of the study are to evaluate the risk of alcohol and tobacco exposure on mortality, hospitalizations, comorbidities, and physiologic frailty for people living with HIV and matched HIV-uninfected controls. Each of the collaborating sites will share aims and study protocols, and will coordinate data management, statistical analysis, and reporting of results to increase sample size, include diverse populations, enhance comparability and generalizability, and maximize impact, as well as utilize resources efficiently.

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