GEARs Combining advances in Genomics and Environmental science to accelerate Actionable Research and practice in ASD

The Autism Centers of Excellence (ACE) program is a trans-NIH initiative that supports large-scale studies on autism spectrum disorder. A priority area for the ACE program is work that will advance our understanding of the biologic mechanisms underlying gene-environment interplay in autism. We intend to create a research consortium with infrastructure to enable the investigation of the interplay of environmental risks with genetic discoveries at scale; build infrastructure for experimental testing of functional biologic impacts of gene-environment interaction; and develop and implement a pipeline for dissemination of findings for primary and secondary prevention efforts.

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