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Genetic and social determinants of pharmacological health outcomes in ancestrally diverse populations

The overarching objective of this proposal is to discover genetic and social determinants of drug safety and efficacy in previously-understudied populations using electronic health record (EHR)-linked biobanks. Aims include determining the impact of social factors on drug effects, identifying genome-wide polymorphisms predictive of drug effects in historically-excluded populations, and discovering eQTL determinants of drug response.

Investigator: Iribarren, Carlos

Funder: National Human Genome Research Institute

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