Impact of gestational SARS-CoV-2 and maternal inflammation on child growth and neurodevelopment in a malaria-endemic setting

Leveraging longitudinal clinical data and samples from mother-infant dyads enrolled in two ongoing NIH-funded trials in Busia, Uganda, with high incidence of malaria and SARS-CoV-2, this study will evaluate the impact of gestational SARS-CoV-2 infection and vaccination on early childhood growth and neurodevelopment, and determine if the effect of gestational SARS-CoV-2 infection and vaccination on infant outcomes is mediated by specific maternal inflammatory pathways.

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