Long-Term Observational Extension of Participants in the CREST-2 Randomized Clinical Trial (C2LOE)

CREST-2 is a multicenter randomized trial of intensive medical management with or without revascularization in patients with asymptomatic high-grade carotid stenosis.This study is a long-term observational extension of participants in the CREST-2 randomized clinical trial (C2LOE) to describe the comparative treatment efficacy over a longer period of expected benefit from revascularization than can be accomplished in the parent trial alone. The study will end
follow-up and report treatment differences when the last patient has been followed for 2 years.

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