Population-Based Epidemiology, Management and Outcomes of Nephrotic Syndrome in Adults and Children: The Kaiser Permanente Nephrotic Syndrome Cohort Study

The aims of this study are to: 1) Assemble a cohort of KPNC adult and pediatric members with nephrotic syndrome and examine temporal trends in the epidemiology of nephrotic syndrome in adults and children between 1996 and 2012, including classification of potential causes. 2) Examine temporal trends in the evaluation and management of nephrotic syndrome in adults and children, overall and in targeted subgroups. 3) Assess predictors of developing nephrotic syndrome in adults and children, overall and by presumptive cause. 4) Characterize the short- and longer-term prognosis of nephrotic syndrome in adults vs. children with regards to renal and cardiovascular outcomes.

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