The study will assess the effects of statin treatment on risk of Alzheimer’s disease and related dementias, controlling for potential confounding and examining potential mediating factors among Kaiser Permanente Northern California members during the years 1996 to 2020. A second aim will examine the role of genetic factors in the association of statin treatment and dementia risk in a cohort of genotyped KPNC members.
Statin Treatment and Incident Alzheimer’s Disease and Related Dementias in a Large, Multi-ethnic Health Plan
Investigator: Schaefer, Catherine
Funder: National Institute on Aging