This study will test the ability of metformin XR (extended release) to reduce the rate of enlargement of existing small- to medium-size abdominal aortic aneurysms with an effect size of 30% compared to placebo and assess the safety and tolerance of daily metformin XR therapy in non-diabetic abdominal aortic aneurysm patients.
The LIMIting AAA with meTformin (LIMIT) Trial
Investigator: Chang, Robert
Funder: National Heart, Lung, and Blood Institute