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Study

Gestational diabetes phenotypes, glucose tolerance transitions and lifestyle behaviors related to cardiovascular risk status

The Study of Women, Infant Feeding, and Type 2 Diabetes after GDM Pregnancy (SWIFT) is a prospective, community-based cohort of mothers aged 20-45 years of age and diagnosed with gestational diabetes mellitus (GDM) who delivered a singleton pregnancy longer than 35 weeks gestation at Kaiser Permanente Northern California in 2008-2011. The new study leverages the SWIFT cohort's rich datasets, and measures blood pressure and novel biomarkers in blood samples obtained at the NIDDK funded 10-year follow up exam. The goal of this ancillary study will evaluate the relationship of GDM phenotype and subsequent transitions in glucose tolerance after GDM pregnancy to cardiovascular disease risk profiles, inflammation, and novel lipid biomarkers as well as effect modification by lifestyle behaviors.
Investigator: Gunderson, Erica
Funder: National Heart, Lung, and Blood Institute