Presti, Joseph
Research interests include refining strategies for prostate cancer screening and detection of high-risk tumors.
Long-term effectiveness of BPH/LUTS pharmacological therapies and using machine learning based predictive analytics to tailor treatment.
This career development award project will compare the effectiveness of pharmacological therapy for lower urinary tract symptoms secondary to benign…
Validation of the Updated Hepatocellular Carcinoma Early Detection Screening Algorithm in a Community-based Cohort of Patients With Cirrhosis of Multiple Etiologies
The Hepatocellular carcinoma (HCC) Early detection Screening (HES) algorithm has been proposed to improve the performance of the serum alpha-fetoprotein…
Racial/Ethnic Disparities in Ovarian Cancer Treatment and Survival: An Integrative Approach
We reported previously that African American and Hispanic women have worse survival after ovarian cancer diagnosis than white women, and…
Implementation of a Multidisciplinary Expert Testicular Cancer Tumor Board Across a Large Integrated Healthcare Delivery System Via Early Case Ascertainment
In 2016, Kaiser Permanente Northern California began regionalizing testicular cancer care using population-based tumor board review. This mixed methods evaluation…
Sleep characteristics and risk of ovarian cancer among postmenopausal women
Several studies have assessed the relationship between sleep duration and ovarian cancer risk, but the results are conflicting. Importantly, no…
Development of a longitudinal two-biomarker algorithm for early detection of ovarian cancer in women with BRCA mutations
To develop a longitudinal algorithm combining two biomarkers, CA125 and HE4, for early detection of ovarian cancer in women with…
Long-term follow-up of a racially and ethnically diverse population of men with localized prostate cancer who did not undergo initial active treatment
There is limited research on the racial/ethnic differences in long-term outcomes for men with untreated, localized prostate cancer. Men diagnosed…
Pathway Analysis of Renal Cell Carcinoma Genome-Wide Association Studies Identifies Novel Associations
Much of the heritable risk of renal cell carcinoma (RCC) associated with common genetic variation is unexplained. New analytic approaches…
Streamlining genetic testing for women with ovarian cancer in a Northern California health care system
Referral to Genetics for pre-testing counseling may be inefficient for women with ovarian cancer. This study assesses feasibility of gynecologic…
Recurrence, Treatment, and Complication Patterns of Intermediate Risk Non-muscle Invasive Bladder Cancer
This study will comprehensively assess the clinical course of intermediate risk non-muscle invasive bladder cancer (NMIBC) in 291 patients diagnosed…
Discussing Cervical Cancer Screening Options: Outcomes to Guide Conversations Between Patients and Providers
Purpose. In 2018, the US Preventive Services Task Force (USPSTF) endorsed three strategies for cervical cancer screening in women ages…
Kaiser Permanente Interregional Cancer Statistics Project
A Kaiser Permanente interregional cancer statistics report will be developed to include incidence and 5-year relative survival rates for breast,…
Does weather trigger urologic chronic pelvic pain syndrome flares? A case-crossover analysis in the multidisciplinary approach to the study of the chronic pelvic pain research network
To investigate whether meteorological factors (temperature, barometric pressure, relative humidity, ultraviolet index [UVI], and seasons) trigger flares in male and…
The effect of multiple recruitment contacts on response rates and patterns of missing data in a survey of bladder cancer survivors 6 months after cystectomy
The Bladder Cancer Quality of Life Study collected detailed and sensitive patient-reported outcomes from bladder cancer survivors in the period…
A Study of Partial Human Papillomavirus Genotyping in Support of the 2019 ASCCP Risk-Based Management Consensus Guidelines
The 2019 ASCCP Risk-Based Management Consensus Guidelines include recommendations for partial human papillomavirus (HPV) genotyping in management of abnormal cervical…
Decision Regret Related to Urinary Diversion Choice Among Cystectomy Patients
Patients who undergo cystectomy due to bladder cancer can elect an ileal conduit or a neobladder for urinary diversion. Decision…
Development of a goal elicitation measure to support bladder cancer patients’ choice about urinary diversion
Patient centered care aims to align treatment with patient goals, especially when treatment options have equivalent clinical outcomes. For surgeries…
Factors that Influence Selection of Urinary Diversion among Bladder Cancer Patients in Three Community-Based Integrated Health Care Systems
To assess the relative contributions of patient and surgeon factors for predicting selection of ileal conduit (IC), neobladder (NB), or…
Recovering from Cystectomy: Patient Perspectives
Bladder cancer patients who undergo cystectomy and urinary diversion face functional and quality-of-life challenges. Little is known about these patients'…
Obesity and renal cell carcinoma risk by histologic subtype: A nested case-control study and meta-analysis
Although obesity is an established risk factor for renal cell carcinoma (RCC), it is unclear whether this relationship varies across…
Lifestyle and nutritional modifiable factors in the prevention and treatment of bladder cancer
Bladder cancer is one of the top 5 most common cancers diagnosed in the U.S. It is also one of…
Diet and Lifestyle in a Prospective Study of Bladder Cancer Survivors
This study involves a new prospective cohort of more than 1,800 non-muscle invasive bladder cancer cases to investigate the role…
Pioglitazone Use and Risk of Bladder Cancer and Other Common Cancers in Persons With Diabetes
Studies suggest pioglitazone use may increase risk of cancers. To examine whether pioglitazone use for diabetes is associated with risk…
Association Between Cannabis Use and the Risk of Bladder Cancer: Results From the California Men’s Health Study
To investigate the association of cannabis use and tobacco smoking on the incidence of bladder cancer within the California Men's…
