Kelly-Taylor, Kendria
Research interests include reproductive health inequities among Black populations.
Li, De-Kun
Research interests include pregnancy outcomes and sudden infant death syndrome.
Identifying Risk Factors for Prenatal Substance and Polysubstance Use
The overarching goal of this K01 study is to identify recent trends in prenatal substance use and develop data-driven, evidence-based,…
Risk of NTD among Live Births Exposed to Maternal Rx Opioids during Early Pregnancy
The objectives of this study are: 1) To measure the association between in utero exposure to prescription opioids during early…
Prenatal, Intrapartum and Infant Antibiotic Use and Atopic Diseases in Childhood
This study has the following aims: 1) Assess prenatal, intrapartum and infant antibiotic exposure in relation to atopic dermatitis, allergic…
Moderate Hypertension in Pregnancy: Safety and Effectiveness of Treatment
The aims of this study are to: 1. Estimate risks of adverse pregnancy outcomes after antihypertensive medication exposure compared to…
Role of Pre-natal Vitamin D and Gene Interactions in Autism Spectrum Disorders: Leveraging an Existing Case-Control Study
This study is the first to investigate the role of perinatal vitamin D deficiency or insufficiency in ASD etiology, as…
Impact of Folate, Obesity and Genetics on Maternal Depression
Research is desperately needed to inform safe and effective interventions for the prevention and treatment of maternal depression. An important…
Risk of Uterine Perforation among Women Using different types of IUDs and the Association with Timing of Insertion and Breastfeeding
The goal of the study is to compare the incidence of uterine perforation within 12 months after IUD insertion between:…
RSV immunoprophylaxis impact on RSV Morbidity and Asthma in Healthy Preterm Infants
The goal of this project is to conduct simulation analyses using an existing dataset (from our AHRQ-funded PRIMA study) to…
Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation
Immune abnormalities have been described in some individuals with autism spectrum disorders (ASDs) as well as their family members. However,…
Comparing Effectiveness of Treating Depression With and Without Comorbidity to Improve Fetal Health
The study is to determine (1) whether treating depression during pregnancy will reduce the risk of adverse pregnancy and pediatric…
Medical Burden Associated with Preterm Labor and Preterm Birth in Kaiser Northern California
The aims of this study are to: 1) Characterize women in the Northern California Kaiser Permanente Medical Care Program (KPMCP)…
Effectiveness of Treating Prenatal Depression to Reduce Postpartum Depression
This is a population-based two-stage cohort study that will take advantage of a new KPNC region-wide program of peripartum screening…
Climate Change and Health: Assessing the Risk of Preterm Delivery
The overall objective of this study is to examine the impact of climate change on the risk of preterm delivery…
Feasibility Study to Assess whether Use of Topiramate during Pregnancy Increases the Risk of Cleft Lips/Palates
To conduct a feasibility study to see if topiramate use during pregnancy increases the risk of cleft palates.
Appropriate Gestational Weight Gain in Overweight/Obese Women
Among overweight/obese pregnant women, we propose to develop and evaluate a randomized diet and physical activity intervention tailored to mothers…
Comparing Effectiveness of Treating Depression With & Without Comorbidity to Improve Fetal Health
This study is to determine: 1) whether treating depression during pregnancy will reduce the risk of adverse pregnancy and pediatric…
Retrospective Cohort Study of Phototherapy and Childhood Cancer in Northern California
To investigate the association between neonatal phototherapy use and childhood cancer. This retrospective cohort study included 499?621 children born at…
Neonatal Phototherapy and Infantile Cancer
To determine whether neonatal phototherapy is associated with cancer in the first year after birth. We analyzed a data set…
HPV16 methyl-haplotypes determined by a novel next-generation sequencing method are associated with cervical precancer
AbstractWe have developed and evaluated a next-generation bisulfite sequencing (NGS) assay to distinguish HPV16 cervical precancer (CIN2-3; N=59) from HPV16-positive…
Prenatal and Newborn Immunoglobulin Levels from Mother-Child Pairs and Risk of Autism Spectrum Disorders
An etiological role for immune factors operating during early brain development in children with autism spectrum disorders (ASD) has not…
External Validation of Early Weight Loss Nomograms for Exclusively Breastfed Newborns
Nomograms that show hour-by-hour percentiles of weight loss during the birth hospitalization were recently developed to aid clinical care of…
Incidence of Dravet Syndrome in a US Population
De novo mutations of the gene sodium channel 1? (SCN1A) are the major cause of Dravet syndrome, an infantile epileptic…
Risk of Sensorineural Hearing Loss and Bilirubin Exchange Transfusion Thresholds
High bilirubin levels are associated with sensorineural hearing loss (SNHL). However, few large studies of relative and excess risk exist.…
Neonatal Neurocritical Care Service Is Associated With Decreased Administration of Seizure Medication
This cohort study examines medication use in term neonates with hypoxic-ischemic encephalopathy and seizures before and after implementation of a…
Gestational Thyrotoxicosis, Antithyroid Drug Use and Neonatal Outcomes within an Integrated Healthcare Delivery System
Increasing attention has focused on the prevalence and outcomes of hyperthyroidism in pregnancy, given concerns for hepatotoxicity and embryopathy associated…
Early weight loss nomograms for formula fed newborns
To develop nomograms depicting percentiles of weight loss by hour of age for both vaginal and cesarean-delivered newborns who are…
A Randomized Clinical Trial of Therapeutic Hypothermia Mode during Transport for Neonatal Encephalopathy
To determine if temperature regulation is improved during neonatal transport using a servo-regulated cooling device when compared with standard practice.…
Risk for Cerebral Palsy in Infants With Total Serum Bilirubin Levels at or Above the Exchange Transfusion Threshold: A Population-Based Study
Exchange transfusion is recommended for newborns with total serum bilirubin (TSB) levels thought to place them at risk for cerebral…
Early weight loss nomograms for exclusively breastfed newborns
The majority of newborns are exclusively breastfed during the birth hospitalization, and weight loss is nearly universal for these neonates.…
Incidence, Etiology, and Outcomes of Hazardous Hyperbilirubinemia in Newborns
Total serum bilirubin (TSB) levels ? 30 mg/dL are rare but potentially hazardous. A better understanding of their incidence, causes,…
Maternal gestational weight gain and offspring risk for childhood overweight or obesity
The objective of the study was to evaluate the association between gestational weight gain, per the 2009 Institute of Medicine…
Evidence of Reproductive Stoppage in Families With Autism Spectrum Disorder: A Large, Population-Based Cohort Study
Few studies have examined the curtailment of reproduction (ie, stoppage) after the diagnosis of a child with autism spectrum disorder…
Prenatal and neonatal peripheral blood mercury levels and autism spectrum disorders
Prenatal and early-life exposures to mercury have been hypothesized to be associated with increased risk of autism spectrum disorders (ASDs).…
Prenatal and perinatal risk factors in a twin study of autism spectrum disorders
Multiple studies associate prenatal and perinatal complications with increased risks for autism spectrum disorders (ASDs). The objectives of this study…
Prevention of Vertical Transmission of Hepatitis B: An Observational Study
For mothers with chronic hepatitis B virus (HBV) infection, the Centers for Disease Control and Prevention recommends immunoprophylaxis to decrease…
Prevalence and Neonatal Factors Associated with Autism Spectrum Disorders in Preterm Infants
To determine the prevalence of autism spectrum disorders (ASD) across gestational age, examine the risk of ASD by gestational age…
Invited Commentary: Does Neonatal Hyperbilirubinemia Cause Asthma?
In an analysis of data from the US Collaborative Perinatal Project, Huang et al. (Am J Epidemiol. 2013;178(12):1691-1697) report an…
Low Prepregnancy Adiponectin Concentrations Are Associated With a Marked Increase in Risk for Development of Gestational Diabetes Mellitus
To examine whether circulating total and high-molecular weight (HMW) adiponectin concentrations, measured before pregnancy, are associated with subsequent risk of…
Risk of Large-for-Gestational-Age Newborns in Women With Gestational Diabetes by Race and Ethnicity and Body Mass Index Categories
OBJECTIVE: To compare the prevalence of large-for-gestational-age (LGA) newborns across categories of body mass index (BMI) in five racial and…
Black Race Is Not Protective Against Hazardous Bilirubin Levels
Although black race is considered protective against hyperbilirubinemia, black infants appear at increased risk of kernicterus. We found that although…
Follow-up testing after colposcopy: five-year risk of CIN 2+ after a colposcopic diagnosis of CIN 1 or less
Most women referred for colposcopy are not diagnosed with cervical intraepithelial neoplasia grade 2 or worse (CIN 2+) but, nonetheless,…
Five-year risks of CIN 3+ and cervical cancer among women with HPV-positive and HPV-negative high-grade Pap results
High-grade Pap results (e.g., atypical glandular cells [AGC], atypical squamous cells cannot rule out HSIL [ASC-H], and high-grade squamous intraepithelial…
Is Infertility Associated with Childhood Autism?
Concerns persist about a possible link between infertility and risk of autism spectrum disorders (ASD). Interpretation of existing studies is…
Pregnancy Glucose Levels in Women without Diabetes or Gestational Diabetes and Childhood Cardiometabolic Risk at 7 Years of Age
OBJECTIVE: To estimate the association between pregnancy glucose values in women without recognized pregestational diabetes or gestational diabetes and cardiometabolic…
Increased risk for respiratory distress among white, male, late preterm and term infants
OBJECTIVE: To determine whether race/ethnicity and sex independently increase risk of respiratory distress syndrome (RDS) in late preterm and term…
Sex ratio variations among the offspring of women with diabetes in pregnancy
AIMS: It has long been hypothesized that natural selection would favour a reproductive strategy biased towards females under adverse circumstances…
Referral to telephonic nurse management improves outcomes in women with gestational diabetes
OBJECTIVE: We sought to determine whether, among women with gestational diabetes mellitus, referral to a telephonic nurse management program was…
Infant siblings and the investigation of autism risk factors
ABSTRACT: Infant sibling studies have been at the vanguard of autism spectrum disorders (ASD) research over the past decade, providing…
Randomised trial comparing hand expression with breast pumping for mothers of term newborns feeding poorly
OBJECTIVE: Breast pumping or hand expression may be recommended when newborns latch or suck poorly. A recent trial found worse…
Antidepressant Use During Pregnancy and Childhood Autism Spectrum Disorders
CONTEXT: The prevalence of autism spectrum disorders (ASDs) has increased over recent years. Use of antidepressant medications during pregnancy also…
A pregnancy and postpartum lifestyle intervention in women with gestational diabetes mellitus reduces diabetes risk factors: a feasibility randomized control trial
OBJECTIVE: To pilot, among women with gestational diabetes mellitus (GDM), the feasibility of a prenatal/postpartum intervention to modify diet and…
Racial and ethnic disparities in postpartum depression care among low-income women
OBJECTIVE: The goal of this study was to characterize racial-ethnic differences in mental health care utilization associated with postpartum depression…
The risk of large for gestational age across increasing categories of pregnancy glycemia
OBJECTIVE: We sought to estimate the risk of large for gestational age (LGA) across categories of glucose tolerance. STUDY DESIGN:…
Neonatally measured immunoglobulins and risk of autism
Previous studies indicate that prenatal exposure to infections is a possible pathway through which autism spectrum disorders (ASD) could be…
Is pregnancy after breast cancer safe?
The impact of treatment on subsequent fertility and the safety of childbearing are major complicating factors for young women diagnosed…
Antenatal ultrasound and risk of autism spectrum disorders
We evaluated antenatal ultrasound (U/S) exposure as a risk factor for autism spectrum disorders (ASD), comparing affected singleton children and…
The population-level impacts of a national health insurance program and franchise midwife clinics on achievement of prenatal and delivery care standards in the Philippines
OBJECTIVES: Adequate prenatal and delivery care are vital components of successful maternal health care provision. Starting in 1998, two programs…
Prenatal exposure to maternal infection and executive dysfunction in adult schizophrenia
OBJECTIVE: Executive dysfunction is one of the most prominent and functionally important cognitive deficits in schizophrenia. Although strong associations have…
Prenatal infection and cavum septum pellucidum in adult schizophrenia
Increased length of the cavum septum pellucidum (CSP) and in utero infection are each associated with increased risk of schizophrenia.…
Prevalence and predictors of perinatal hemorrhagic stroke: results from the kaiser pediatric stroke study
OBJECTIVES: Predictors for perinatal arterial ischemic stroke include both maternal and intrapartum factors, but predictors of perinatal hemorrhagic stroke have…
Trends in postpartum diabetes screening and subsequent diabetes and impaired fasting glucose among women with histories of gestational diabetes mellitus: A report from the Translating Research Into Action for Diabetes (TRIAD) Study
OBJECTIVE: The purpose of this study was to examine trends in postpartum glucose screening for women with gestational diabetes mellitus…
Mothers of children diagnosed with attention-deficit/hyperactivity disorder: health conditions and medical care utilization in periods before and after birth of the child
BACKGROUND: Analyzing health conditions and medical utilization of mothers of children with attention-deficit/hyperactivity disorder (ADHD) can shed light on biologic,…
Long-term blood pressure changes measured from before to after pregnancy relative to nonparous women
OBJECTIVE: To prospectively examine whether blood pressure changes persist after pregnancy among women of reproductive age. METHODS: This was a…
Maternal iron deficiency and the risk of schizophrenia in offspring
CONTEXT: Iron is essential for brain development and functioning. Emerging evidence suggests that iron deficiency in early life leads to…
Maternal mid-pregnancy autoantibodies to fetal brain protein: the early markers for autism study
BACKGROUND: Immune dysfunction has been associated with autism, yet whether maternal immune status during pregnancy plays a causal role remains…
Maternal Rh D status, anti-D immune globulin exposure during pregnancy, and risk of autism spectrum disorders
OBJECTIVE: The objective of the study was to investigate the association between maternal Rh D status, prenatal exposure to anti-D…
Breast-feeding and diabetes: long-term impact on mothers and their infants
In the general population, breast-feeding is associated with a reduced risk of the offspring being overweight later in life by…
Brain-derived neurotrophic factor and autism: maternal and infant peripheral blood levels in the Early Markers for Autism (EMA) Study
To investigate levels of brain-derived neurotrophic factor (BDNF) in mid-pregnancy and neonatal blood specimens as early biologic markers for autism,…
Autism: maternally derived antibodies specific for fetal brain proteins
Autism is a profound disorder of neurodevelopment with poorly understood biological origins. A potential role for maternal autoantibodies in the…
Maternal and paternal age and risk of autism spectrum disorders
OBJECTIVE: To explore the association between maternal and paternal age and risk of autism spectrum disorders (ASDs) in offspring. DESIGN:…
Congenital anomalies associated with autism spectrum disorders
This study examined whether major congenital structural anomalies identified in infancy occurred more frequently in children later diagnosed with autism…
Maternal autoimmune diseases, asthma and allergies, and childhood autism spectrum disorders: a case-control study
OBJECTIVE: To investigate the association between physician-documented diagnoses of maternal autoimmune diseases, allergies, and asthma around the time of pregnancy…
Neonatal hyperbilirubinemia and risk of autism spectrum disorders
OBJECTIVE: To investigate the association between neonatal hyperbilirubinemia and autism spectrum disorders (ASD). METHODS: We conducted a large case-control study…
The key role of newborn thyroid scintigraphy with isotopic iodide (123I) in defining and managing congenital hypothyroidism
BACKGROUND: Thyroid imaging with isotopic iodide (123I) or technetium Tc 99m pertechnetate has been available for decades but is not…
Effectiveness of influenza vaccine during pregnancy in preventing hospitalizations and outpatient visits for respiratory illness in pregnant women and their infants
The Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention recommends influenza vaccination for women who…
Detection of postpartum depression and anxiety in a large health plan
To determine the prevalence of diagnosed and/or treated postpartum depression and anxiety, records were extracted for 1 year after delivery…
Gestational diabetes mellitus and lesser degrees of pregnancy hyperglycemia: association with increased risk of spontaneous preterm birth
OBJECTIVE: To investigate whether different degrees of maternal glucose intolerance are associated with the risk of spontaneous preterm birth. METHODS:…
How accurately does the medical record capture maternal history of cancer?
We sought to assess the reliability of information regarding the maternal history of cancer by comparing the medical records of…
