Quesenberry, Charles P.
Research interests include epidemiologic and statistical methods.
Research interests include epidemiologic and statistical methods.
Research focuses on the development, application, and dissemination of statistical methodologies.
Research interests include assessment of the effectiveness and safety of vaccines and drugs.
Research interests include risk factors for disease and prediction modeling
Research interests include alcohol and health and perinatal substance abuse.
The Delivery Science Rapid Analysis Program will create a mechanism to solicit, prioritize, and address rapidly researchable analytic questions with…
Observational studies reporting on adjusted associations between childhood body mass index (BMI; weight (kg)/height (m)2) rebound and subsequent cardiometabolic outcomes…
Advances in the modeling and analysis of electronic health records (EHR) have the potential to improve patient risk stratification, leading…
Methods exist to study exposure mixtures, but each is distinct in the research question it aims to address. We propose…
Linear regression is often used to estimate associations between chemical exposures and neurodevelopment at the mean of the outcome. However,…
The inverse probability weighted Cox proportional hazards model can be used to estimate the marginal hazard ratio. In multi-site studies,…
The Bladder Cancer Quality of Life Study collected detailed and sensitive patient-reported outcomes from bladder cancer survivors in the period…
Bias arises in studies of waning vaccine effectiveness when higher-risk individuals are depleted from the at-risk population at different rates…
In pharmacogenomic studies of quantitative change, any association between genetic variants and the pretreatment (baseline) measurement can bias the estimate…
Estimating hazard ratios (HR) presents challenges for propensity score (PS)-based analyses of cohorts with differential depletion of susceptibles. When the…
In health informatics, there have been concerns with reuse of electronic health data for research, including potential bias from incorrect…
Catheter ablation has brought major advances in the management of patients with atrial fibrillation (AF). As evidenced by multiple randomized…
Concerns about reverse causality and selection bias complicate the interpretation of studies of body mass index (BMI, calculated as weight…
This study will provide a comprehensive program of infrastructure development, methods development, and innovative research to generate real-world evidence addressing…
Periviable infants (i.e., those born in the 20th through 26th weeks of gestation) suffer much morbidity and approximately half die…
Beginning in 2005, researchers at Kaiser Permanente Northern California (KPNC) Division of Research developed the Research Program on Genes, Environment,…
This study develops generalized per-protocol analyses based on Inverse Probability Weighting and Targeted Learning to control for or evaluate the…
This report describes the results of recruitment efforts and the subsequent participation of pregnant women in study activities in a…
Use of electronic health records (EHRs) in health research may lead to the false assumption of complete event ascertainment. We…
The clinical deterioration of patientsin general hospital wards is an important safety issue. Aggregate-weighted early warning systems (EWSs) may not…
To assess sampling bias in national viral suppression (VS) estimates derived from the Medical Monitoring Project (MMP) resulting from use…
Henry Ford Health System, Kaiser Permanente Colorado, Kaiser Permanente Northern California, Kaiser Permanente Northwest, and Kaiser Permanente Southern California are…
PURPOSE OF REVIEW: We offer an in-depth discussion of the time-varying confounding and selection bias mechanisms that give rise to…
The Advisory Committee on Immunization Practices recommends Hepatitis B (HepB) vaccine for previously unvaccinated adults
The need for a systematic approach to research on vaccine effectiveness (VE) is increasing with growing numbers of vaccines and…
Single-method assessment of physical activity (PA) has limitations. The utility and cross-validation of a composite PA score that includes reported…
In this study, Kaiser Permanente Northern California researchers will serve as consultants for U.S. Department of Veterans Affairs (VA) researchers…
The purpose of this project is to examine quality indicators for key chronic conditions such as diabetes and asthma for…
Body mass index (BMI), a proxy measure for obesity, is determined by both environmental (including ethnicity, age, and sex) and…
Privacy-protecting analytic and data-sharing methods that minimize the disclosure risk of sensitive information are increasingly important due to the growing…
Colonoscopy examination does not always detect colorectal cancer (CRC)- some patients develop CRC after negative findings from an examination. When…
There is widespread concern about the use of body mass index (BMI) to define obesity status in postmenopausal women because…
A large and increasing proportion of health care costs are spent caring for a small segment of medically and socially…
Some parents are concerned the childhood immunization schedule could increase risk for allergic disorders, including asthma. To inform future safety…
Multiple sclerosis (MS) incidence has increased recently, particularly in women, suggesting a possible role of one or more environmental exposures…
Postapproval drug safety studies often use propensity scores (PSs) to adjust for a large number of baseline confounders. These studies…
This project aims to determine whether fields included in the National Institutes of Health’s Patient Reported Outcomes Measurement System (PROMIS)…
The Society of Family Planning (SFP), Planned Parenthood Federation of America (PPFA), and the Association of Reproductive Health Professionals (ARHP)…
The new Kaiser Permanente Your Current Life Situation (YCLS) screening questionnaire will be mailed to a random sample of 7,000…
The Automated Self-Administered 24-hour Dietary Assessment Tool (ASA24) includes a highly standardized multipass web-based recall that, like the Automated Multiple…
Four decades ago, U.S. life expectancy was within the same range as other high-income peer countries. However, during the past…
This study aims to determine whether specific items from two questionnaires currently in use at Kaiser Permanente Northern California (the…
New health policies may have intended and unintended consequences. Active surveillance of population-level data may provide initial signals of policy…
Timely follow-up for positive cancer screening results remains suboptimal, and the evidence base to inform decisions on optimizing the timeliness…
Self-rated health (SRH) is an independent predictor of mortality; studies have investigated correlates of SRH to explain this predictive capability…
The objective of our study was to conduct a data mining analysis to identify potential adverse events (AEs) following MENACWY-D…
This project consists of tasks required for data partners in the Food and Drug Administration’s Sentinel Initiative under the initiative’s…
This study will examine whether significant differences across Asian ethnic groups in prevalence of chronic diseases, behavioral and psychosocial risk…
In 1991, we described the recruitment and goals for a cohort of young adults. At the time, little was known…
The purpose of the study was to assess the feasibility of quantifying long-term trends in breast tumor DNA copy number…
Very large international and ethnic differences in cancer rates exist, are minimally explained by genetic factors, and show the huge…
We sought to build on the template-matching methodology by incorporating longitudinal comorbidities and acute physiology to audit hospital quality. Patients…
The need to develop methods for studying the safety of childhood immunization schedules has been recognized by the Institute of…
The Institute of Medicine recommended conducting observational studies of childhood immunization schedule safety. Such studies could be biased by outcome…
Electronic medical record (EMR) systems provide easy access to radiology reports and offer great potential to support quality improvement efforts…
This is a pilot study to determine the feasibility of conducting a prospective study that aims to characterize longitudinal trajectories…
Comparative safety studies typically use hierarchical treatment categories that lump monotherapy and combination therapy. The consequence of this approach on…
Estimates of the prevalence of Parkinson's disease in North America have varied widely and many estimates are based on small…
Cord blood DNA methylation is associated with numerous health outcomes and environmental exposures. Whole cord blood DNA reflects all nucleated…
Abdominal fat may be a better predictor than body mass index (BMI) for risk of metabolically-related diseases, such as diabetes,…
The Study of Transition, Outcomes and Gender (STRONG) was initiated to assess the health status of transgender people in general…
Introduction: Socio-economic status (SES) and low health literacy (LHL) are closely correlated. Both are directly associated with clinical and behavioral…
Autism Spectrum Disorder (ASD) is one of the fastest-growing developmental disorders in the United States. It was hypothesized that variations…
When evaluating safety signals, there is often interest in understanding safety in all patients for whom compared treatments are reasonable…
Often, studies modeling an exposure's influence on time to disease-specific death from study enrollment are incorrectly interpreted as if based…
This article is not a traditional research report. It describes how conducting a specific set of benchmarking analyses led us…
Health care researchers and delivery system leaders share a common mission to improve health care quality and outcomes. However, differing…
Cancer cachexia remains understudied and there are no standard treatments available despite the publication of an international consensus definition and…
Involving patients as partners in research is a defining characteristic of patient-centered outcomes research (PCOR). While patients' experiential knowledge of…
PurposeThe Clinical Sequencing Exploratory Research (CSER) Consortium encompasses nine National Institutes of Health-funded U-award projects investigating translation of genomic sequencing…
We examined the feasibility of conducting a longitudinal study of diet among diverse populations by comparing rates of response throughout…
Expanding research capacity of large research networks within health care delivery systems requires strategically training both embedded and external investigators…
BACKGROUND:Ofatumumab (Arzerra®, Novartis) is a treatment for chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab [double refractory (DR-CLL)]. Ofatumumab was…
OBJECTIVE: Despite the challenges of managing type 1 diabetes, many adolescents achieve optimal outcomes. A validated measure of diabetes-specific strengths is…
In the 20 years since the initial consensus on a common definition for restless legs syndrome (RLS), over 600 scientific…
This is a methodological study that will utilize our established PRIMA cohort to develop statistical methods for (a) quantifying and…
This study aims to strengthen causal inferences based on Marginal Structural Modeling (MSM) and large healthcare databases for Comparative Effectiveness…
The simcausal R package is a tool for specification and simulation of complex longitudinal data structures that are based on…
Childhood socioeconomic status (cSES) is a powerful predictor of adult health, but its operationalization and measurement varies across studies. Using…
An understanding of factors influencing health in socioeconomic groups is required to reduce health inequalities. This study investigated combinations of…
AbstractWe study the framework for semi-parametric estimation and statistical inference for the sample average treatment-specific mean effects in observational settings…
The ability to collect data on patients for long periods prior to, during, and after a cancer diagnosis is critical…
Understanding costs and ensuring that we demonstrate value in healthcare is a foundational presumption as we transform the way we…
Sweeping changes in health care financing combined with the increased use of technology across health care systems are making it…
An observational study of the Kaiser Permanente Northern California (KPNC) BMI coding distributions was conducted to ascertain the trends in…
Body composition may be a better predictor of chronic disease risk than body mass index (BMI) in older populations.OBJECTIVES:We sought…
Both quality improvement and clinical research efforts over the past few decades have focused on consensus definition of sepsis and…
We sought to develop and validate an instrument that can enable providers to identify young women who may be at…
Consistent estimation of causal effects with inverse probability weighting estimators is known to rely on consistent estimation of propensity scores…
The growing availability of electronic health data provides an opportunity to ascertain diagnosis-specific cases via systematic methods for sample recruitment…
Most studies of sleep and health outcomes rely on self-reported sleep duration, although correlation with objective measures is poor. In…
To compare information from self-report and electronic medical records for four common comorbidities (diabetes, hypertension, myocardial infarction, and other heart…
We describe a novel algorithm for identifying transgender people and determining their male-to-female (MTF) or female-to-male (FTM) identity in electronic…
The utility of data-based algorithms in research has been questioned because of errors in identification of cancer recurrences. We adapted…
The objective of this study was to evaluate a pilot program that allowed Chicago field center participants of the Coronary…
The Patient-Centered Outcomes Research Institute (PCORI) created a new national network infrastructure to enable large-scale observational comparative effectiveness research across…
Strategies for identifying the most relevant psychosocial predictors in studies of racial/ethnic minority women's health are limited because they largely…
The development and approval of an efficacious pharmacotherapy for stimulant use disorders has been limited by the lack of a…
Improving the ability to risk-stratify patients is critical for efficiently allocating resources within healthcare systems. The purpose of this study…
Few large studies describe quality control procedures and reproducibility findings in cardiovascular ultrasound, particularly in novel techniques such as speckle…
To identify factors associated with valid Autism Spectrum Disorder (ASD) diagnoses from electronic sources in large healthcare systems. We examined…
The high-dimensional propensity score (hdPS) algorithm was proposed for automation of confounding adjustment in problems involving large healthcare databases. It…
This study aims to develop a self-report questionnaire assessing the impact of vaginal dryness, soreness, itching, irritation, and pain on…
An efficient approach to characterizing the disease burden of rare genetic variants is to impute them into large well-phenotyped cohorts…
Network meta-analysis is increasingly used to allow comparison of multiple treatment alternatives simultaneously, some of which may not have been…
Breastfeeding is associated with reduced risk of becoming overweight or obese later in life. Breastfed babies grow more slowly during…
Integrated health care delivery systems, with their comprehensive and integrated electronic medical records (EMR), are well-poised to conduct research that…
Genome-wide association studies have uncovered a large number of genetic variants associated with type 2 diabetes or related phenotypes. In…
Funding agencies and researchers increasingly recognize the importance of patient stakeholder engagement in research. Despite calls for greater patient engagement,…
Large healthcare databases maintained by health plans have been widely used to conduct customized protocol-based epidemiological safety studies as well…
Breast cancer has a complex etiology that includes genetic, biologic, behavioral, environmental, and social factors. Etiologic factors are frequently studied…
The objective of this study is to determine whether summary estimates of a self-report physical activity questionnaire that does not…
Dietary assessment has long been known to be challenged by measurement error. A substantial amount of literature on methods for…
To develop glycaemic goal individualization algorithms and assess potential impact on a healthcare system and different segments of the population…
Comparative effectiveness studies using electronic health records (EHRs) often define chronic kidney disease (CKD) outcomes using laboratory-based definitions. Recommendations for…
In comparative effectiveness research (CER), often the aim is to contrast survival outcomes between exposure groups defined by time-varying interventions…
In studies that use electronic health record data, imputation of important data elements such as Glycated hemoglobin (A1c) has become…
PFC serum concentrations were measured in 6-8 year-old girls in Greater Cincinnati (GC) (N = 353) and the San Francisco…
This report describes the Menopausal Strategies: Finding Lasting Answers to Symptoms and Health network and methodological issues addressed in designing…
Data-sharing is encouraged to fulfill the ethical responsibility to transform research data into public health knowledge, but data sharing carries…
Comparative effectiveness research methods are used to compare the effect of four distinct glucose-control strategies on subsequent myocardial infarction and…
It is increasingly necessary to analyze data from multiple sources when conducting public health safety surveillance or comparative effectiveness research…
OBJECTIVE: To propose a unifying set of definitions for prescription adherence research utilizing electronic health record prescribing databases, prescription dispensing…
OBJECTIVE: Clinical trials are unlikely to ever be launched for many comparative effectiveness research (CER) questions. Inferences from hypothetical randomized…
BACKGROUND: A distributed research network (DRN) of electronic health care databases, in which data reside behind the firewall of each…
OBJECTIVES: To compare the performance of a targeted maximum likelihood estimator (TMLE) and a collaborative TMLE (CTMLE) to other estimators…
OBJECTIVE: To examine the attitudes of US patients about the use of placebo treatments in medical care. DESIGN: One time…
The purpose of this study was to determine whether e-mail contact is a viable method for gathering information from adolescent…
Genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) associated with complex traits. However, the genetic heritability of…
As the number of cancer survivors continues to grow, research investigating the factors that affect cancer outcomes, such as disease…
In 2010, the Washington Circle convened a meeting, supported by the National Institute on Drug Abuse (NIDA) and the Substance…
Breast cancer patients have voiced dissatisfaction regarding their education on breast cancer-related lymphedema risk and risk reduction strategies from their…
BACKGROUND: Analyses from double-blind randomized trials have reported lower mortality among participants who were more adherent to placebo compared with…
One of the identifiability assumptions of causal effects defined by marginal structural model (MSM) parameters is the experimental treatment assignment…
OBJECTIVE: The aim of this study was to evaluate monitors for assessing vasomotor symptoms (VMS) in laboratory and ambulatory settings…
Large prospective cohort studies are critical for identifying etiologic factors for disease, but they require substantial long-term research investment. Such…
BACKGROUND: Randomized controlled trials have reported lower mortality among patients who adhere to placebo compared with those who do not…
AKI is an important clinical problem that has become increasingly more common. Mortality rates associated with AKI remain high despite…
AKI remains an important clinical problem, with a high mortality rate, increasing incidence, and no Food and Drug Administration-approved therapeutics…
Acute kidney injury (AKI) remains a complex clinical problem associated with significant short-term morbidity and mortality and lacking effective pharmacologic…
Very preterm birth (VPTB) is a leading cause of infant mortality, morbidity and racial disparity in the US. The underlying…
PURPOSE: Chronic disease care typically involves treatment decisions that are frequently adjusted to the patient's evolving clinical course (e.g., hemoglobin…
This study modeled predementia Alzheimer's disease clinical trials. Longitudinal data from cognitively normal (CN) and mild cognitive impairment (MCI) participants…
PURPOSE: Many challenges arise when conducting a sequentially monitored medical product safety surveillance evaluation using observational electronic data captured during…
Active medical product monitoring systems, such as the Sentinel System, will utilize electronic healthcare data captured during routine health care…
CONTEXT: Numerous instruments to measure self-reported physical activity (PA) exist, but there is little guidance for determining the most appropriate…
PURPOSE: To assess case-only designs for surveillance with administrative databases. METHODS: We reviewed literature on two designs that are observational…
CONTEXT: Advances in device-based measures have led researchers to question the value of reported measures of physical activity or sedentary…
BACKGROUND: Modern clinical-research practice favors placebo controls over usual-care controls whenever a credible placebo exists. An unrecognized consequence of this…
Four custom Axiom genotyping arrays were designed for a genome-wide association (GWA) study of 100,000 participants from the Kaiser Permanente…
INTRODUCTION AND HYPOTHESIS: This study aims to measure self-report urinary incontinence questions' reproducibility and agreement with bladder diary. METHODS: Data…
BACKGROUND: Although biologic treatments have excellent efficacy for many autoimmune diseases, safety concerns persist. Understanding the absolute and comparative risks…
OBJECTIVE: To examine the value of adding an urge incontinence question to the American Urological Association Symptom Index (AUASI) among…
In randomized trials, investigators typically rely upon an unadjusted estimate of the mean outcome within each treatment arm to draw…
The success of genome-wide association studies has paralleled the development of efficient genotyping technologies. We describe the development of a…
BACKGROUND: There is a paucity of literature comparing Bayesian analytic techniques with traditional approaches for analyzing clinical trials using real…
PURPOSE: Data in epidemiological studies sometimes are collected off-schedule from planned study visits. In an ancillary study to the Study…
BACKGROUND: Societal preference-weighted health-related quality of life (HRQOL) scores enable comparing multidimensional health states across diseases and treatments for research…
The MATRICS Psychometric and Standardization Study was conducted as a final stage in the development of the MATRICS Consensus Cognitive…
The growth curve modeling (GCM) technique has been widely adopted in longitudinal studies to investigate progression over time. The simplest…
Multiple-day diet records can be unsuitable for cohort studies because of high administrative and analytical costs. Costs could be reduced…
BACKGROUND: A provocative finding from several double-blind clinical trials has been the association between greater adherence to placebo study medication…
PURPOSE: The optimal method to assess human epidermal growth factor receptor 2 (HER2) status remains highly controversial. Before reporting patient…
OBJECTIVES: The objective of this study was to describe the assessment methods and maturation status for a multisite cohort of…
Due to the complex nature of common diseases, their etiology is likely to involve 'uncommon but strong' (UBS) interactive effects--i.e…
The authors evaluated the association between ambient ozone levels and cardiac mortality in California's South Coast Air Basin during the…
Systematic differences between readers or equipment in imaging studies are not uncommon; failure to account for such differences when using…
OBJECTIVE: To evaluate and compare the use of 6 different methods for calculating expected mortality rates and standardized mortality ratios…
Translational research seeks to improve health care by promoting action and change in real-world health care settings. Although translational research…
BACKGROUND: A reliable and valid questionnaire for screening restless legs syndrome (RLS) is essential for determining accurate estimates of disease…
OBJECTIVE: Describe a novel approach to comprehensively summarize medication adherence. DATA SOURCES/STUDY SETTING: Kaiser Permanente Northern California Diabetes Registry (n…
PURPOSE: To describe the concerns raised by health plan members, providers and purchasers related to studying the comparative effectiveness of…
PURPOSE: Active surveillance of population-based health networks may improve the timeliness of detection of adverse events (AEs). Our objective was…
BACKGROUND: Meeting recruitment goals is challenging for many clinical trials conducted in primary care populations. Little is known about how…
Many epidemiologic studies include symptom checklists assessing recall of symptoms over a specified time period. Little research exists regarding the…
BACKGROUND: A clear need exists for a more systematic understanding of the epidemiology, diagnosis, and management of cardiovascular diseases. More…
A variety of methods are available for estimating genetic admixture proportions in populations; however, few investigators have conducted detailed comparisons…
BACKGROUND: Genetic association studies conducted in admixed populations may be confounded by population stratification resulting in spurious associations. The purpose…
BACKGROUND: Despite ethical imperatives, informing research participants about the results of the studies in which they take part is not…
PURPOSE: Active surveillance of population-based health networks may improve the timeliness of detection of adverse drug events (ADEs). Active monitoring…
BACKGROUND: Cluster randomized trials (CRTs) offer unique advantages over standard randomized controlled clinical trials (RCTs) and observational methodologies, and may…
BACKGROUND: Despite consensus about the importance of measuring quality of diabetes care and the widespread use of self-reports and medical…
OBJECTIVE: The purpose of this study was to determine the concordance of patient recall compared with chart abstraction for distant…
BACKGROUND: Hormonally active environmental agents have been measured among U.S. children using exposure biomarkers in urine. However, little is known…
Twin designs, comparing correlations in monozygotic (MZ) versus dizygotic (DZ) twins, have an extensive history. One major confounder in such…
OBJECTIVE: To assess barriers to physician participation in cancer clinical trials among oncologists, oncology leaders, and health plan leaders. STUDY…
A cohort of 197 Medicaid-insured patients presenting for treatment in Kaiser Permanente's outpatient chemical dependency treatment program were observed the…
Withdrawal of participants from randomized trials can occur because of symptoms thought to be related to the study medicine, but…
Background: Voluntary reporting systems identify only a fraction of medical errors. Electronic identification mechanisms, which are more efficient, have been…
Understanding and eliminating health disparities requires accurate data on race/ethnicity. To assess the quality of race/ethnicity data, we compared medical…
PURPOSE: Information on patient ethnicity in hospital admissions databases is often used in epidemiologic and health services research. However, the…
OBJECTIVES: To study health status and hospitalization risk among Asian Americans. DESIGN: Cross-sectional analyses and cohort study. SETTING: Comprehensive prepaid…
BACKGROUND: Plasma carotenoid concentrations reflect intake of vegetables and fruits, the major food sources of these compounds. This study compared…
Understanding the long-term course of problematic drinking is a fundamental concern for health services research in the alcohol field. The…
INTRODUCTION: Many proponents of hospice care believe that this service is underutilized. OBJECTIVE: To determine physicians' perceptions of hospice utilization…
OBJECTIVE: To determine the sensitivity and positive predictive value (PPV) of computerized diagnostic data from health maintenance organizations (HMOs) in…
Population laboratories with complete clinical information on episodes of care are needed to support research on the quality of care…
OBJECTIVE: The purpose of this study was to determine whether an unengaged vertex significantly increased the risk of cesarean delivery…
OBJECTIVE: To determine the meaning of S(i) = 0 derived from the frequently sampled intravenous glucose tolerance test. RESEARCH DESIGN…
OBJECTIVE: The purpose of this study was to determine whether rates of hypertensive disorders of pregnancy increase beyond 37 weeks…
HYPOTHESIS: Patients aged 70 years and older undergo proportionately more emergency and permanent fecal ostomy procedures than younger patients. Older…
OBJECTIVE: To implement a computerized system to gather and transmit medical record information from six sites to a centralized database…
STUDY OBJECTIVE: We determine the reproducibility of increased blood pressure measurements among adults in the emergency department or minor injury…
Oxidation of biomolecules may play a role in susceptibility to a number of diseases. However, there are few large-scale survey…
BACKGROUND: Although health-related quality of life (HRQL) has been increasingly used as an outcome in asthma, its utility for identifying…
This paper discusses the results from the field test of a multimedia health education intervention, designed to provide breast cancer…
Although many Medicaid beneficiaries receive health care through commercial health maintenance organizations (HMOs), the impact of private managed care on…
OBJECTIVES: Describe the development of a questionnaire to assess past year physical activity, including activities of daily living, in a…
Errors in measuring dietary intake can threaten validity of data. Low-energy reporters (LER) are individuals who report lower levels of…
Ultrasound is the imaging study of choice for the detection of gallstones, but ultrasound through medical imaging departments (MI Sono)…
OBJECTIVE: Given the directive of the American Academy of Pediatrics to test children for tuberculosis (TB) only if they are…
CONTEXT: ICU patients are often rendered incapable of making decisions as a result of their illness. The accuracy with which…
In many health services applications, research to determine the effectiveness of a particular treatment cannot be carried out using a…
We sought to assess the reliability of information regarding the maternal history of cancer by comparing the medical records of…
The liberal use of ultrasonography has been advocated in patients with first trimester cramping or bleeding to avoid misdiagnosis of…
BACKGROUND: The number of shots in the childhood immunization schedule has been increasing and is likely to continue to increase…
This paper describes the Prenatal Determinants of Schizophrenia (PDS) Study; three companion papers report the first results. The PDS Study…
OBJECTIVE: This study sought to evaluate the benefit of utilizing a nutritionist review of a self-administered food frequency questionnaire (FFQ),…
OBJECTIVE: To examine the relation of the facial nerve to the only identifiable surgical landmark in the external auditory canal…
This study developed and evaluated the performance of prediction models for asthma-related adverse outcomes based on the computerized hospital, clinic,…
AIM: Different time frames have been used to ask about drinking in clinical and general populations. Surveys of clinical populations…
The performances of two commonly used diet instruments, the Block and the Willett food frequency questionnaires, were compared with a…
OBJECTIVE: In a health maintenance organization population, we determined the incidence of early-onset (at less than or equal to 7…
To evaluate the function and effectiveness of a multidisciplinary team for managing human immunodeficiency virus (HIV) infection, we conducted a…
The Women's Health Initiative (WHI) is a large and complex clinical investigation of strategies for the prevention and control of…
In epidemiologic studies, total energy intake is often related to disease risk because of associations between physical activity or body…
In 1984, a prospective cohort study, Coronary Artery Risk Development in Young Adults (CARDIA) was initiated to investigate life-style and…
Coronary Artery Disease Risk Development in Young Adults (CARDIA) is a longitudinal study designed to trace the development of risk…