Elizabeth M. Cespedes Feliciano, ScD, SM

Open-Source Algorithms for Radiomic Analyses

Open-Source Algorithms for Body Composition Assessment
This project will test open-source algorithms for body composition assessment by implementing them on KPNC data and analyzing the output. Not only will this provide novel data for an ongoing grant, but it will also produce a practical playbook for future users of such tools.
Funder: KPNC Community Health

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Investigator: Feliciano, Elizabeth

Funder: Northern California Community Benefit Programs

Long-Term Trajectories of Accelerated Biological Aging and Functional Decline Associated with Breast Cancer and its Treatment

We combine three decades of clinical, self-reported, and physiological data from the Women’s Health Initiative to characterize long-term trajectories of physical function in breast cancer survivors and test whether they are modified by intensity of cancer treatments; test whether breast cancer and its treatments increase the rate of epigenetic aging and whether the rate of epigenetic aging continues to accelerate after treatment; and examine the relationship between the rate of epigenetic aging and functional decline and test whether it differs between breast cancer survivors and usual aging controls.

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Investigator: Feliciano, Elizabeth

Funder: National Cancer Institute

Body composition and breast cancer survival: immune and metabolic biomarkers in breast tumors – Disparities Supplement

This is a supplement with the long-term goal to reduce the disproportionate burden of breast cancer mortality experienced by non-Hispanic black (NHB) women by understanding the role of a key, modifiable risk factor: excess adiposity.

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Investigator: Feliciano, Elizabeth

Funder: National Cancer Institute

Understanding the role of adipose tissue distribution and adipokine-related RNA expression in the tumor microenvironment on breast cancer outcomes in a racially and ethnically diverse sample

We will test the central hypothesis that adipose tissue depots (visceral vs. subcutaneous), measured using computed tomography scans, have differing associations with adipokine and adipokine receptor gene expression profiles and related gene signatures in the breast tumor microenvironment, which can be used to develop outcome predictive models. This study will (1) Examine whether adipose tissue distribution impacts cell type-specific RNA expression profiles of leptin, adiponectin, and their receptors in breast tumors and the adjacent breast TME; (2) Define associations of these RNA expression profiles with breast tumor clinicopathology; and (3) Examine whether these RNA expression profiles predict breast cancer recurrence and mortality.

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Investigator: Feliciano, Elizabeth

Funder: National Cancer Institute

Informatics approaches to assessing patient frailty in surgical care

Patient frailty increases the risk for surgical complications, which are common, costly, and deadly, especially for older Americans. To improve surgical care for older adults, we will investigate whether electronic measures of frailty can help reduce complications by identifying which patients are likely to be readmitted to the hospital or die soon after surgery.

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Investigator: Feliciano, Elizabeth

Funder: National Institute on Aging

Body Composition and Breast Cancer Survival: Immune and Metabolic Biomarkers in Breast Tumors

We previously found that one third of nonmetastatic breast cancer patients had sarcopenia (age-related loss of muscle tissue) at the time of their diagnosis and that having sarcopenia and obesity was associated with an 89% increased risk of death. This study will use 1,400 archived clinical tumor tissues from stage II-III breast cancer patients for whom we have data on body composition, metabolic syndrome, weight history, cancer therapy, and long-term follow-up for breast cancer outcomes. We will classify breast cancer molecular subtypes, measure gene expression levels in immune and metabolic pathways potentially influenced by body composition and the metabolic syndrome, and examine whether  alterations in the breast cancer tumor microenvironment mediate the association of body composition and breast cancer survival.

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Investigator: Feliciano, Elizabeth

Funder: National Cancer Institute

D3-creatine dilution to assess skeletal muscle mass in colon cancer patients

Among colon cancer patients participating in a resistance training intervention during chemotherapy, this study will examine whether a new method to evaluate skeletal muscle mass (d3-creatine dilution) is associated with the key cancer outcomes of strength and physical function, chemotherapy toxicity, inflammation, cardiometabolic risk factors and markers of tumor recurrence.

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Investigator: Feliciano, Elizabeth

Funder: National Cancer Institute

Pediatric obstructive sleep apnea: predictive modeling to streamline care

To prioritize pediatric attended polysomnography and treatment for children most in need while reducing the unnecessary use of overnight sleep studies, we propose to build and rigorously evaluate a clinical risk prediction model. We will combine data from pediatric sleep questionnaires with other risk factors derived from the electronic medical record to predict obstructive sleep apnea severity among pediatric sleep patients and evaluate our model’s performance in an independent sample. 

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Investigator: Feliciano, Elizabeth

Funder: The Permanente Medical Group

Healthful dietary patterns, intermediate biomarkers and long-term breast cancer prognosis

To strengthen the dietary guidelines for breast cancer survivors, we examine whether at-diagnosis concordance with healthful dietary patterns is associated with recurrence or breast cancer death, or with prognostic biomarkers (i.e., body composition, inflammation or metabolic syndrome). Secondarily, we will examine whether improving diet quality (or maintaining high diet quality) after diagnosis reduces risk of recurrence or breast cancer death.

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Investigator: Feliciano, Elizabeth

Funder: American Institute for Cancer Research

Beyond Body Mass Index: Bringing Body Composition into Oncology Practice

This project consists of development of electronic tools to rapidly assess body composition in colorectal cancer and breast cancer patients and present this information to clinicians. It leverages Kaiser Permanente Northern California’s electronic medical records and repository of CT images, including 6,000 images from colorectal cancer and breast cancer patients that were previously manually analyzed for body composition. This project has three major aims: validate software to automatically assess body composition from clinically-acquired imaging (Aim 1); improve the predictive performance of established colorectal cancer risk prediction models through the addition of body composition variables (Aim 2); and develop a prototype of an electronic decision support tool that presents personalized patient risk information to clinicians in an understandable and actionable format (Aim 3).

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Investigator: Feliciano, Elizabeth

Funder: National Cancer Institute

Effect of resistance training on physical function during chemotherapy in colon cancer

Authors: Brown, Justin C;Yang, Shengping;Compton, Stephanie L E;Campbell, Kristin L;Cespedes Feliciano, Elizabeth M;Quinney, Sara;Sternfeld, Barbara;Caan, Bette J;Meyerhardt, Jeffrey A;Schmitz, Kathryn H

JNCI Cancer Spectr. 2024 Jul 01;8(4).

PubMed abstract

Automated CT Analysis of Body Composition as a Frailty Biomarker in Abdominal Surgery

Authors: Fumagalli, Ijeamaka Anyene;Le, Sidney T;Peng, Peter D;Kipnis, Patricia;Liu, Vincent X;Caan, Bette;Chow, Vincent;Beg, Mirza Faisal;Popuri, Karteek;Cespedes Feliciano, Elizabeth M

JAMA Surg. 2024 Apr 10.

PubMed abstract

A novel body composition risk score (B-Score) and overall survival among patients with nonmetastatic breast cancer

Authors: Cheng, En;Caan, Bette J;Chen, Wendy Y;Prado, Carla M;Cespedes Feliciano, Elizabeth M

Clin Nutr. 2024 Apr;43(4):981-987. Epub 2024-03-06.

PubMed abstract

Effect of home-based resistance training on chemotherapy relative dose intensity and tolerability in colon cancer: The FORCE randomized control trial

Authors: Caan, Bette J;Lee, Catherine;Quesenberry, Charles P;Cespedes Feliciano, Elizabeth M;Schmitz, Kathryn H;et al.

Cancer. 2024 Jan 24.

PubMed abstract

A protocol for remote collection of skeletal muscle mass via D3-creatine dilution in community-dwelling postmenopausal women from the Women’s Health Initiative

Authors: Banack, Hailey R;Wactawski-Wende, Jean;Ochs-Balcom, Heather M;Feliciano, Elizabeth M Cespedes;Caan, Bette;Lee, Catherine;Anderson, Garnet;Shankaran, Mahalakshmi;Evans, William J

PLoS One. 2024;19(4):e0300140. Epub 2024-04-17.

PubMed abstract

D3-creatine dilution, computed tomography and dual-energy X-ray absorptiometry for assessing myopenia and physical function in colon cancer: A cross-sectional study

Authors: Cheng, En;Sternfeld, Barbara;Cespedes Feliciano, Elizabeth M;Cespedes Feliciano, Elizabeth M;et al.

J Cachexia Sarcopenia Muscle. 2023 Dec;14(6):2768-2778. Epub 2023-10-30.

PubMed abstract

Hypothetical interventions on diet quality and lifestyle factors to improve breast cancer survival: the Pathways Study

Authors: Ergas, Isaac J;Bradshaw, Patrick T;Cespedes Feliciano, Elizabeth M;Roh, Janise M;Kwan, Marilyn L;Laraia, Barbara;Madsen, Kristine A;Yao, Song;Thomsen, Catherine;Kushi, Lawrence H

Cancer Epidemiol Biomarkers Prev. 2023 Dec 01;32(12):1716-1725.

PubMed abstract

Changes in physical function in older women with endometrial cancer with or without adjuvant therapy

Authors: Quick, Allison M;Cespedes Feliciano, Elizabeth M;Paskett, Electra;et al.

J Cancer Surviv. 2023 Sep 05.

PubMed abstract

Alcohol consumption and prognosis and survival in breast cancer survivors: The Pathways Study

Authors: Kwan, Marilyn L;Valice, Emily;Ergas, Isaac J;Roh, Janise M;Caan, Bette J;Cespedes Feliciano, Elizabeth M;Kolevska, Tatjana;Hartman, Terryl J;Quesenberry, Charles P;Ambrosone, Christine B;Kushi, Lawrence H

Cancer. 2023 Aug 09.

PubMed abstract

Body Composition, Relative Dose Intensity, and Adverse Events Among Patients with Colon Cancer

Authors: Cheng, En;Campbell, Kristin L;Schmitz, Kathryn H;Cespedes Feliciano, Elizabeth M;et al.

Cancer Epidemiol Biomarkers Prev. 2023 Jul 14.

PubMed abstract

Associations of post-diagnosis lifestyle with prognosis in women with invasive breast cancer

Authors: Troeschel, Alyssa N;McCullough, Lauren E;Collin, Lindsay J;Bradshaw, Patrick T;Valice, Emily;Kushi, Lawrence H;et al.

Cancer Epidemiol Biomarkers Prev. 2023 Jul 05;32(7):963-975.

PubMed abstract

Intermittent fasting interventions to leverage metabolic and circadian mechanisms for cancer treatment and supportive care outcomes

Authors: Kalam, Faiza;James, Dara L;Li, Yun Rose;Coleman, Michael F;Kiesel, Violet A;Cespedes Feliciano, Elizabeth M;Hursting, Stephen D;Sears, Dorothy D;Kleckner, Amber S

J Natl Cancer Inst Monogr. 2023 May 04;2023(61):84-103.

PubMed abstract

Cachexia: A systemic consequence of progressive, unresolved disease

Authors: Ferrer, Miriam;Brown, Justin C;Caan, Bette J;Janowitz, Tobias;et al.

Cell. 2023 Apr 27;186(9):1824-1845.

PubMed abstract

Association of Inflammatory Biomarkers With Survival Among Patients With Stage III Colon Cancer

Authors: Cheng, En; Caan, Bette J; Cespedes Feliciano, Elizabeth M; Meyerhardt, Jeffrey A; et al.

JAMA Oncol. 2023 Mar 01;9(3):404-413.

PubMed abstract

Long-term Trajectories of Physical Function Decline in Women With and Without Cancer

Authors: Cespedes Feliciano, Elizabeth M; Quesenberry, Charles; Caan, Bette J; Anderson, Garnet L; et al.

JAMA Oncol. 2023 Mar 01;9(3):395-403.

PubMed abstract

Sleep duration, plasma metabolites, and obesity and diabetes: A metabolome-wide association study in US women

Authors: Fritz, Josef; Cespedes Feliciano, Elizabeth M; Vetter, Céline; et al.

Sleep. 2023 Jan 11;46(1).

PubMed abstract

Metabolic abnormalities and survival among patients with non-metastatic breast cancer

Authors: Zimbalist, Alexa S; Caan, Bette J; Chen, Wendy Y; Mittendorf, Elizabeth A; Dillon, Deborah A R; Quesenberry, Charles; Cespedes Feliciano, Elizabeth M

BMC Cancer. 2022 Dec 29;22(1):1361. Epub 2022-12-29.

PubMed abstract

Adipose tissue radiodensity and mortality among patients with nonmetastatic breast cancer

Authors: Cheng, En; Caan, Bette J; Chen, Wendy Y; Irwin, Melinda L; Prado, Carla M; Cespedes Feliciano, Elizabeth M

Clin Nutr. 2022 Dec;41(12):2607-2613. Epub 2022-10-04.

PubMed abstract

Body composition from single versus multi-slice abdominal computed tomography: Concordance and associations with colorectal cancer survival

Authors: Anyene, Ijeamaka; Caan, Bette; Williams, Grant R; Popuri, Karteek; Lenchik, Leon; Giri, Smith; Chow, Vincent; Beg, Mirza Faisal; Cespedes Feliciano, Elizabeth M

J Cachexia Sarcopenia Muscle. 2022 Dec;13(6):2974-2984. Epub 2022-09-02.

PubMed abstract

Quantifying Frailty Requires a Conceptual Model Before a Statistical Model-Reply

Authors: Le, Sidney T; Liu, Vincent X; Cespedes Feliciano, Elizabeth M

JAMA Surg. 2022 Nov 01;157(11):1065-1066.

PubMed abstract

Adiposity and cancer survival: a systematic review and meta-analysis

Authors: Cheng, En; Kirley, Jocelyn; Cespedes Feliciano, Elizabeth M; Caan, Bette J

Cancer Causes Control. 2022 Oct;33(10):1219-1246. Epub 2022-08-15.

PubMed abstract

Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity-related cancer risk and mortality in Black and Latina Women’s Health Initiative participants

Authors: Pichardo, Margaret S; Cespedes Feliciano, Elizabeth M; Irwin, Melinda L; et al.

Cancer. 2022 10;128(20):3630-3640. Epub 2022-08-23.

PubMed abstract

Association of sleep duration and insomnia with metabolic syndrome and its components in the Women’s Health Initiative

Authors: Peila, Rita; Allison, Matthew; Rohan, Thomas E; et al.

BMC Endocr Disord. 2022 Sep 14;22(1):228. Epub 2022-09-14.

PubMed abstract

The association of abdominal adiposity with premature discontinuation of postoperative chemotherapy in colon cancer

Authors: Brown, Justin C; Meyerhardt, Jeffrey A; Cespedes Feliciano, Elizabeth M; Cheng, En; Caan, Bette J

Clin Nutr. 2022 Jul;41(7):1600-1604. Epub 2022-05-27.

PubMed abstract

Diabetes Incidence Among Hispanic/Latino Adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Authors: Cordero, Christina; Espinoza Giacinto, Rebeca A; Avilés-Santa, Larissa; et al.

Diabetes Care. 2022 06 02;45(6):1482-1485.

PubMed abstract

Trajectories of objectively measured physical function among older breast cancer survivors in comparison with cancer-free controls

Authors: Luo, Juhua; Carter, Stephen J; Feliciano, Elizabeth M Cespedes; Hendryx, Michael

Breast Cancer Res Treat. 2022 Jun;193(2):467-476. Epub 2022-03-26.

PubMed abstract

Predicting obstructive sleep apnea severity in children referred for polysomnography: use of the Pediatric Sleep Questionnaire and Subscales

Authors: Bseikri, Mustafa; Zhang, Jie; Kirley, Jocelyn; Lee, Catherine; Castillo, Adrienne; Feliciano, Elizabeth M Cespedes

Sleep Breath. 2022 May 28.

PubMed abstract

Comparison of Electronic Frailty Metrics for Prediction of Adverse Outcomes of Abdominal Surgery

Authors: Le, Sidney T; Liu, Vincent X; Kipnis, Patricia; Zhang, Jie; Peng, Peter D; Cespedes Feliciano, Elizabeth M

JAMA Surg. 2022 05 01;157(5):e220172. Epub 2022-05-11.

PubMed abstract

Greater Body Fatness Is Associated With Higher Protein Expression of LEPR in Breast Tumor Tissues: A Cross-Sectional Analysis in the Women’s Circle of Health Study

Authors: Llanos, Adana A M; Cespedes Feliciano, Elizabeth M; Demissie, Kitaw; et al.

Front Endocrinol (Lausanne). 2022;13:879164. Epub 2022-06-29.

PubMed abstract

Neighborhood and Individual Socioeconomic Disadvantage and Survival Among Patients With Nonmetastatic Common Cancers

Authors: Cheng, En; Soulos, Pamela R; Irwin, Melinda L; Cespedes Feliciano, Elizabeth M; Presley, Carolyn J; Fuchs, Charles S; Meyerhardt, Jeffrey A; Gross, Cary P

JAMA Netw Open. 2021 12 01;4(12):e2139593. Epub 2021-12-01.

PubMed abstract

Abdominal adipose tissue radiodensity is associated with survival after colorectal cancer

Authors: Feliciano, Elizabeth M Cespedes; Winkels, Renate M; Meyerhardt, Jeffrey A; Prado, Carla M; Afman, Lydia A; Caan, Bette J

Am J Clin Nutr. 2021 12 01;114(6):1917-1924.

PubMed abstract

Plant-Based Dietary Patterns and Breast Cancer Recurrence and Survival in the Pathways Study

Authors: Anyene, Ijeamaka C; Ergas, Isaac J; Kwan, Marilyn L; Roh, Janise M; Ambrosone, Christine B; Kushi, Lawrence H; Cespedes Feliciano, Elizabeth M

Nutrients. 2021 Sep 25;13(10). Epub 2021-09-25.

PubMed abstract

Weight stability masks changes in body composition in colorectal cancer: a retrospective cohort study

Authors: Brown, Justin C; Caan, Bette J; Cespedes Feliciano, Elizabeth M; Xiao, Jingjie; Weltzien, Erin; Prado, Carla M; Kroenke, Candyce H; Castillo, Adrienne; Kwan, Marilyn L; Meyerhardt, Jeffrey A

Am J Clin Nutr. 2021 06 01;113(6):1482-1489.

PubMed abstract

Alignment of dietary patterns with the Dietary Guidelines for Americans 2015-2020 and risk of all-cause and cause-specific mortality in the Women’s Health Initiative Observational Study

Authors: George, Stephanie M; Cespedes Feliciano, Elizabeth M; Caan, Bette J; Neuhouser, Marian L; et al.

Am J Epidemiol. 2021 05 04;190(5):886-892.

PubMed abstract

Predictive Value of DXA Appendicular Lean Mass for Incident Fractures, Falls, and Mortality, Independent of Prior Falls, FRAX, and BMD: Findings from the Women’s Health Initiative (WHI)

Authors: Harvey, Nicholas C; Cespedes Feliciano, Elizabeth M; McCloskey, Eugene; et al.

J Bone Miner Res. 2021 04;36(4):654-661. Epub 2021-01-28.

PubMed abstract

Diet Quality and Breast Cancer Recurrence and Survival: The Pathways Study

Authors: Ergas, Isaac J; Cespedes Feliciano, Elizabeth M; Bradshaw, Patrick T; Roh, Janise M; Kwan, Marilyn L; Cadenhead, Jen; Santiago-Torres, Margarita; Troeschel, Alyssa N; Laraia, Barbara; Madsen, Kristine; Kushi, Lawrence H

JNCI Cancer Spectr. 2021 04;5(2). Epub 2021-03-02.

PubMed abstract

Recruitment strategies and design considerations in a trial of resistance training to prevent dose-limiting toxicities in colon cancer patients undergoing chemotherapy

Authors: Caan, Bette J; Meyerhardt, Jeffrey A; Brown, Justin C; Campbell, Kristin L; Cespedes Feliciano, Elizabeth M; Lee, Catherine; Ross, Michelle C; Quinney, Sara; Quesenberry, Charles; Sternfeld, Barbara; Schmitz, Kathryn H

Contemp Clin Trials. 2021 02;101:106242. Epub 2020-12-07.

PubMed abstract

Sleep characteristics and risk of ovarian cancer among postmenopausal women

Authors: Liang, Xiaoyun; Harris, Holly R; Hendryx, Michael; Shadyab, Aladdin H; Hale, Lauren; Li, Yueyao; Crane, Tracy E; Cespedes Feliciano, Elizabeth M; Stefanick, Marcia L; Luo, Juhua

Cancer Prev Res (Phila). 2021 01;14(1):55-64. Epub 2020-09-11.

PubMed abstract

Association of Low Muscle Mass and Low Muscle Radiodensity With Morbidity and Mortality for Colon Cancer Surgery

Authors: Xiao, Jingjie; Cespedes Feliciano, Elizabeth M; Meyerhardt, Jeffrey A; Kwan, Marilyn L; Alexeeff, Stacey E; Castillo, Adrienne L; Prado, Carla M; et al.

JAMA Surg. 2020 10 01;155(10):942-949.

PubMed abstract

Deep learning method for localization and segmentation of abdominal CT

Authors: Dabiri, Setareh; Popuri, Karteek; Ma, Cydney; Chow, Vincent; Feliciano, Elizabeth M Cespedes; Caan, Bette J; Baracos, Vickie E; Beg, Mirza Faisal

Comput Med Imaging Graph. 2020 10;85:101776. Epub 2020-08-14.

PubMed abstract

Evaluation of automated computed tomography segmentation to assess body composition and mortality associations in cancer patients

Authors: Cespedes Feliciano EM; Liu V; Caan BJ; et al.

J Cachexia Sarcopenia Muscle. 2020 10;11(5):1258-1269. Epub 2020-04-20.

PubMed abstract

Association of Prediagnostic Frailty, Change in Frailty Status, and Mortality After Cancer Diagnosis in the Women’s Health Initiative

Authors: Cespedes Feliciano, Elizabeth M; Hohensee, Chancellor; Rosko, Ashley E; Anderson, Garnet L; Paskett, Electra D; Zaslavsky, Oleg; Wallace, Robert B; Caan, Bette J

JAMA Netw Open. 2020 09 01;3(9):e2016747. Epub 2020-09-01.

PubMed abstract

Postdiagnosis Physical Activity: Association With Long-Term Fatigue and Sleep Disturbance in Older Adult Breast Cancer Survivors

Authors: Vasbinder A; Reding KW; Wang D; Han CJ; Zaslavsky O; Langford D; Cespedes Feliciano EM; Barrington WE; Paskett ED

Clin J Oncol Nurs. 2020 08 01;24(4):381-391.

PubMed abstract

Identifying metabolomic profiles of inflammatory diets in postmenopausal women

Authors: Tabung FK; Liang L; Rexrode KM; et al.

Clin Nutr. 2020 05;39(5):1478-1490. Epub 2019-06-17.

PubMed abstract

Body Composition, Adherence to Anthracycline and Taxane-Based Chemotherapy, and Survival After Nonmetastatic Breast Cancer

Authors: Cespedes Feliciano EM; Chen WY; Lee V; Albers KB; Prado CM; Alexeeff S; Xiao J; Shachar SS; Caan BJ

JAMA Oncol. 2020 02 01;6(2):264-270.

PubMed abstract

Adipose Tissue Distribution and Cardiovascular Disease Risk Among Breast Cancer Survivors

Authors: Cespedes Feliciano EM; Chen WY; Bradshaw PT; Prado CM; Alexeeff S; Albers KB; Castillo AL; Caan BJ

J Clin Oncol. 2019 10 01;37(28):2528-2536. Epub 2019-08-01.

PubMed abstract

Chronotype, Social Jet Lag, and Cardiometabolic Risk Factors in Early Adolescence

Authors: Cespedes Feliciano EM; Rifas-Shiman SL; Quante M; Redline S; Oken E; Taveras EM

JAMA Pediatr. 2019 Sep 16.

PubMed abstract

Association of Daily Rest-Activity Patterns With Adiposity and Cardiometabolic Risk Measures in Teens

Authors: Quante M; Cespedes Feliciano EM; Rifas-Shiman SL; Mariani S; Kaplan ER; Rueschman M; Oken E; Taveras EM; Redline S

J Adolesc Health. 2019 08;65(2):224-231. Epub 2019-05-02.

PubMed abstract

Muscle segmentation in axial computed tomography (CT) images at the lumbar (L3) and thoracic (T4) levels for body composition analysis

Authors: Dabiri S; Popuri K; Cespedes Feliciano EM; Caan BJ; Baracos VE; Beg MF

Comput Med Imaging Graph. 2019 07;75:47-55. Epub 2019-05-09.

PubMed abstract

Body Composition and Cardiovascular Events in Patients With Colorectal Cancer: A Population-Based Retrospective Cohort Study

Authors: Brown JC; Caan BJ; Prado CM; Weltzien E; Xiao J; Cespedes Feliciano EM; Kroenke CH; Meyerhardt JA

JAMA Oncol. 2019 Jul 01;5(7):967-972.

PubMed abstract

Identifying Metabolomic Profiles of Insulinemic Dietary Patterns

Authors: Tabung FK; Balasubramanian R; Liang L; Clinton SK; Cespedes Feliciano EM; Manson JE; Van Horn L; Wactawski-Wende J; Clish CB; Giovannucci EL; Rexrode KM

Metabolites. 2019 Jun 24;9(6). Epub 2019-06-24.

PubMed abstract

Adipose Tissue Distribution and Survival Among Women with Nonmetastatic Breast Cancer

Authors: Bradshaw PT; Cespedes Feliciano EM; Prado CM; Alexeeff S; Albers KB; Chen WY; Caan BJ

Obesity (Silver Spring). 2019 06;27(6):997-1004. Epub 2019-04-25.

PubMed abstract

The association of medical and demographic characteristics with sarcopenia and low muscle radiodensity in patients with nonmetastatic colorectal cancer

Authors: Xiao J; Caan BJ; Cespedes Feliciano EM; Meyerhardt JA; Kroenke CH; Baracos VE; Weltzien E; Kwan ML; Alexeeff SE; Castillo AL; Prado CM

Am J Clin Nutr. 2019 03 01;109(3):615-625.

PubMed abstract

Associations Between Timing of Meals, Physical Activity, Light Exposure, and Sleep With Body Mass Index in Free-Living Adults

Authors: Marinac CR; Quante M; Mariani S; Weng J; Redline S; Cespedes Feliciano EM; Hipp JA; Wang D; Kaplan ER; James P; Mitchell JA

J Phys Act Health. 2019 03 01;16(3):214-221. Epub 2019-02-24.

PubMed abstract

Non-alcoholic fatty liver disease and colorectal cancer survival

Authors: Wu K; Zhai MZ; Weltzien EK; Cespedes Feliciano EM; Meyerhardt JA; Giovannucci E; Caan BJ

Cancer Causes Control. 2019 Feb;30(2):165-168. Epub 2018-11-15.

PubMed abstract

The evolution of body composition in oncology-epidemiology, clinical trials, and the future of patient care: facts and numbers

Authors: Brown JC; Cespedes Feliciano EM; Caan BJ

J Cachexia Sarcopenia Muscle. 2018 Dec;9(7):1200-1208. Epub 2019-01-13.

PubMed abstract

Clinical implications of low skeletal muscle mass in early-stage breast and colorectal cancer

Authors: Cespedes Feliciano E; Chen WY

Proc Nutr Soc. 2018 11;77(4):382-387. Epub 2018-06-04.

PubMed abstract

The Obesity Paradox in Cancer: How Important Is Muscle?

Authors: Cespedes Feliciano EM; Kroenke CH; Caan BJ

Annu Rev Nutr. 2018 08 21;38:357-379. Epub 2018-05-04.

PubMed abstract

Associations of pre-existing co-morbidities with skeletal muscle mass and radiodensity in patients with non-metastatic colorectal cancer

Authors: Xiao J; Caan BJ; Weltzien E; Cespedes Feliciano EM; Kroenke CH; Meyerhardt JA; Baracos VE; Kwan ML; Castillo AL; Prado CM

J Cachexia Sarcopenia Muscle. 2018 08;9(4):654-663. Epub 2018-04-19.

PubMed abstract

Screening for low muscularity in colorectal cancer patients: a valid, clinic-friendly approach that predicts mortality

Authors: Cespedes Feliciano EM; Avrutin E; Caan BJ; Boroian A; Mourtzakis M

J Cachexia Sarcopenia Muscle. 2018 Jul 31.

PubMed abstract

Muscle radiodensity and mortality in patients with colorectal cancer

Authors: Kroenke CH; Prado CM; Meyerhardt JA; Weltzien EK; Xiao J; Cespedes Feliciano EM; Caan BJ

Cancer. 2018 07 15;124(14):3008-3015. Epub 2018-05-24.

PubMed abstract

Objective Sleep Characteristics and Cardiometabolic Health in Young Adolescents

Authors: Cespedes Feliciano EM; Quante M; Rifas-Shiman SL; Redline S; Oken E; Taveras EM

Pediatrics. 2018 07;142(1). Epub 2018-06-15.

PubMed abstract

Association of Muscle and Adiposity Measured by Computed Tomography With Survival in Patients With Nonmetastatic Breast Cancer

Authors: Caan BJ; Cespedes Feliciano EM; Prado CM; Alexeeff S; Kroenke CH; Bradshaw P; Quesenberry CP; Weltzien EK; Castillo AL; Olobatuyi TA; Chen WY

JAMA Oncol. 2018 06 01;4(6):798-804.

PubMed abstract

The deterioration of muscle mass and radiodensity is prognostic of poor survival in stage I-III colorectal cancer: a population-based cohort study (C-SCANS)

Authors: Brown JC; Caan BJ; Weltzien E; Cespedes Feliciano EM; Kroenke CH; Castillo A; Kwan ML; Prado CM; et al.

J Cachexia Sarcopenia Muscle. 2018 May 15.

PubMed abstract

An Empirical Dietary Inflammatory Pattern Score Is Associated with Circulating Inflammatory Biomarkers in a Multi-Ethnic Population of Postmenopausal Women in the United States

Authors: Tabung FK; Cespedes Feliciano EM; Rexrode KM; et al.

J Nutr. 2018 Apr 20.

PubMed abstract

The Plausibility of the Obesity Paradox in Cancer-Response-Reply to Point

Authors: Cespedes Feliciano EM; Kroenke CH; Caan BJ

Cancer Res. 2018 04 15;78(8):1904-1905.

PubMed abstract

The Importance of Body Composition in Explaining the Overweight Paradox in Cancer-Counterpoint

Authors: Caan BJ; Cespedes Feliciano EM; Kroenke CH

Cancer Res. 2018 04 15;78(8):1906-1912.

PubMed abstract

Cardiometabolic risk factors and survival after breast cancer in the Women’s Health Initiative

Authors: Simon MS; Cespedes Feliciano EM; Caan B; et al.

Cancer. 2018 04 15;124(8):1798-1807. Epub 2018-01-16.

PubMed abstract

Change in longitudinal trends in sleep quality and duration following breast cancer diagnosis: results from the Women’s Health Initiative

Authors: Beverly CM; Naughton MJ; Pennell ML; Foraker RE; Young G; Hale L; Feliciano EMC; Pan K; Crane TE; Danhauer SC; Paskett ED

NPJ Breast Cancer. 2018;4:15. Epub 2018-06-29.

PubMed abstract

Actigraphy-Derived Daily Rest-Activity Patterns and Body Mass Index in Community-Dwelling Adults

Authors: Cespedes Feliciano EM; Hipp JA; et al.

Sleep. 2017 12 01;40(12).

PubMed abstract

Methodological considerations for disentangling a risk factor’s influence on disease incidence versus postdiagnosis survival: The example of obesity and breast and colorectal cancer mortality in the Women’s Health Initiative

Authors: Cespedes Feliciano EM; Ho GYF; Caan BJ; et al.

Int J Cancer. 2017 12 01;141(11):2281-2290. Epub 2017-08-31.

PubMed abstract

Association of Systemic Inflammation and Sarcopenia With Survival in Nonmetastatic Colorectal Cancer: Results From the C SCANS Study

Authors: Feliciano EMC; Kroenke CH; Kwan ML; Alexeeff S; Corley D; Caan BJ; et al.

JAMA Oncol. 2017 12 01;3(12):e172319.

PubMed abstract

Muscle mass at the time of diagnosis of nonmetastatic colon cancer and early discontinuation of chemotherapy, delays, and dose reductions on adjuvant FOLFOX: The C-SCANS study

Authors: Cespedes Feliciano EM; Lee VS; Prado CM; Meyerhardt JA; Alexeeff S; Kroenke CH; Xiao J; Castillo AL; Caan BJ

Cancer. 2017 Sep 07.

PubMed abstract

Body mass index, PAM50 subtype, recurrence and survival among patients with nonmetastatic breast cancer

Authors: Cespedes Feliciano EM; Kwan ML; Kushi LH; Chen WY; Weltzien EK; Castillo AL; Sweeney C; Bernard PS; Caan BJ

Cancer. 2017 Jul 01;123(13):2535-2542. Epub 2017-03-13.

PubMed abstract

Explaining the Obesity Paradox: The Association between Body Composition and Colorectal Cancer Survival (C-SCANS Study)

Authors: Caan BJ; Meyerhardt JA; Kroenke CH; Alexeeff S; Xiao J; Weltzien E; Feliciano EC; Castillo AL; Quesenberry CP; Kwan ML; Prado CM

Cancer Epidemiol Biomarkers Prev. 2017 07;26(7):1008-1015. Epub 2017-05-15.

PubMed abstract

Adiposity, post-diagnosis weight change, and risk of cardiovascular events among early-stage breast cancer survivors

Authors: Cespedes Feliciano EM; Kwan ML; Kushi LH; Weltzien EK; Castillo AL; Caan BJ

Breast Cancer Res Treat. 2017 04;162(3):549-557. Epub 2017-02-07.

PubMed abstract

Physical activity induced protection against breast cancer risk associated with delayed parity

Authors: Sturgeon KM; Schweitzer A; Leonard JJ; Tobias DK; Liu Y; Cespedes Feliciano E; Malik VS; Joshi A; Rosner B; De Jonghe BC

Physiol Behav. 2017 Feb 01;169:52-58. Epub 2016-11-21.

PubMed abstract

Actigraphic Sleep Patterns of U.S. Hispanics: The Hispanic Community Health Study/Study of Latinos

Authors: Dudley KA; Weng J; Sotres-Alvarez D; Simonelli G; Cespedes Feliciano E; Ramirez M; Ramos AR; Loredo JS; Reid KJ; Mossavar-Rahmani Y; Zee PC; Chirinos DA; Gallo LC; Wang R; Patel SR

Sleep. 2017 Feb 01;40(2).

PubMed abstract

Post-diagnosis Weight Change and Survival Following a Diagnosis of Early Stage Breast Cancer

Authors: Cespedes Feliciano EM; Kroenke CH; Bradshaw PT; Chen WY; Prado CM; Weltzien EK; Castillo AL; Caan BJ

Cancer Epidemiol Biomarkers Prev. 2017 Jan;26(1):44-50. Epub 2016-08-26.

PubMed abstract

Association of Weight Change after Colorectal Cancer Diagnosis and Outcomes in the Kaiser Permanente Northern California Population

Authors: Meyerhardt JA; Kroenke CH; Prado CM; Kwan ML; Castillo A; Weltzien E; Cespedes Feliciano EM; Xiao J; Caan BJ

Cancer Epidemiol Biomarkers Prev. 2017 Jan;26(1):30-37. Epub 2016-12-16.

PubMed abstract

Variation in actigraphy-estimated rest-activity patterns by demographic factors

Authors: Mitchell JA; Glanz K; Kerr J; et al.

Chronobiol Int. 2017;34(8):1042-1056. Epub 2017-06-26.

PubMed abstract

Change in Dietary Patterns and Change in Waist Circumference and DXA Trunk Fat Among Postmenopausal Women

Authors: Cespedes Feliciano EM; Tinker L; Manson JE; Allison M; Rohan T; Zaslavsky O; Waring ME; Asao K; Garcia L; Rosal M; Neuhouser ML

Obesity (Silver Spring). 2016 Oct;24(10):2176-84. Epub 2016-08-22.

PubMed abstract

Physical activity from menarche to first pregnancy and risk of breast cancer

Authors: Liu Y; Tobias DK; Sturgeon KM; Rosner B; Malik V; Cespedes E; Joshi AD; Eliassen AH; Colditz GA

Int J Cancer. 2016 Sep 15;139(6):1223-30. Epub 2016-05-17.

PubMed abstract

Metabolic Dysfunction, Obesity, and Survival Among Patients With Early-Stage Colorectal Cancer

Authors: Cespedes Feliciano EM; Kroenke CH; Kwan ML; Quesenberry C; Caan BJ; et al.

J Clin Oncol. 2016 Sep 6.

PubMed abstract

What Should Cardiologists Tell Their Patients About a Healthy Dietary Pattern?

Authors: Hu FB; Cespedes Feliciano EM

J Am Coll Cardiol. 2016 08 23;68(8):815-7.

PubMed abstract

Association between sleeping difficulty and type 2 diabetes in women

Authors: Li Y; Gao X; Winkelman JW; Cespedes EM; Jackson CL; Walters AS; Schernhammer E; Redline S; Hu FB

Diabetologia. 2016 Apr;59(4):719-27. Epub 2016-01-28.

PubMed abstract

Comparison of Self-Reported Sleep Duration With Actigraphy: Results From the Hispanic Community Health Study/Study of Latinos Sueño Ancillary Study.

Authors: Cespedes, Elizabeth M EM; Hu, Frank B FB; Redline, Susan S; Rosner, Bernard B; Alcantara, Carmela C; Cai, Jianwen J; Hall, Martica H MH; Loredo, Jose S JS; Mossavar-Rahmani, Yasmin Y; Ramos, Alberto R AR; Reid, Kathryn J KJ; Shah, Neomi A NA; Sotres-Alvarez, Daniela D; Zee, Phyllis C PC; Wang, Rui R; Patel, Sanjay R SR

American journal of epidemiology. 2016 Mar 15;183(6):561-73. Epub 2016-03-02.

PubMed abstract

Multiple Healthful Dietary Patterns and Type 2 Diabetes in the Women’s Health Initiative.

Authors: Cespedes EM; Hu FB; Tinker L; Rosner B; Redline S; Garcia L; Hingle M; Van Horn L; Howard BV; Levitan EB; Li W; Manson JE; Phillips LS; Rhee JJ; Waring ME; Neuhouser ML

American journal of epidemiology. 2016 Apr 01;183(7):622-33. Epub 2016-03-02.

Long-term changes in sleep duration, energy balance and risk of type 2 diabetes

Authors: Cespedes EM; Bhupathiraju SN; Li Y; Rosner B; Redline S; Hu FB

Diabetologia. 2016 Jan;59(1):101-9. Epub 2015-Nov-02.

PubMed abstract

Television viewing, bedroom television, and sleep duration from infancy to mid-childhood.

Authors: Cespedes, Elizabeth M EM; Gillman, Matthew W MW; Kleinman, Ken K; Rifas-Shiman, Sheryl L SL; Redline, Susan S; Taveras, Elsie M EM

Pediatrics. 2014 May ;133(5):e1163-71. Epub 2014-04-14.

PubMed abstract