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High prevalence of vitamin D deficiency in patients with basal cell nevus syndrome

OBJECTIVES: To evaluate vitamin D status in patients with basal cell nevus syndrome (BCNS) who practice photoprotection because of their genetic predisposition to skin cancer and to determine risk factors for deficiency. DESIGN: Retrospective cohort study. SETTING: Academic medical centers. PATIENTS: Forty-one ambulatory patients with BCNS who participated in a 2-year chemoprevention clinical trial. Population-based controls (n = 360) were selected and matched by age, sex, Fitzpatrick skin type, and season/geography. MAIN OUTCOME MEASURES: Levels of 25-hydroxyvitamin D (25[OH]D) and vitamin D deficiency (defined as a 25[OH]D level of

Authors: Tang JY; Wu A; Linos E; Parimi N; Lee W; Aszterbaum M; Asgari MM; Bickers DR; Epstein EH

Arch Dermatol. 2010 Oct;146(10):1105-10.

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