To describe self-reported menopausal symptom priorities and their association with demographics and other symptoms among participants in an intervention trial for vasomotor symptoms (VMS). Cross-sectional study embedded in the MsFLASH 02 trial, a three-by-two factorial design of yoga vs. exercise vs. usual activity and omega-3-fatty acid vs. placebo. At baseline, women (n?=?354) completed hot flush diaries, a card sort task to prioritize symptoms they would most like to alleviate, and standardized questionnaires. The most common symptom priorities were: VMS (n?=?322), sleep (n?=?191), concentration (n?=?140), and fatigue (n?=?116). In multivariate models, women who chose VMS as their top priority symptom (n?=?210) reported significantly greater VMS severity (p?=?0.004) and never smoking (p?=?0.012), and women who chose sleep as their top priority symptom (n?=?100) were more educated (p???0.001) and had worse sleep quality (p?0.001). ROC curves identified sleep scale scores that were highly predictive of ranking sleep as a top priority symptom. Among women entering an intervention trial for VMS and with relatively low prevalence of depression and anxiety, VMS was the priority symptom for treatment. A card sort may be a valid tool for quickly assessing symptom priorities in clinical practice and research.
MsFLASH participants’ priorities for alleviating menopausal symptoms
Authors: Carpenter JS; Sternfeld B; LaCroix AZ; et al.
Climacteric. 2015;18(6):859-66. Epub 2015-10-30.