Alyce S. Adams, PhD

People

Balancing Treatment Outcomes and Medication Burden among Patients with Symptomatic Diabetic Peripheral Neuropathy

This project is a continuation of a study we recently conducted to identify and prioritize treatment outcomes of relevance to patients with diabetic peripheral neuropathy (DPN). DPN affects 30% to 50% of all adults with diabetes and symptoms such as pain, tingling, numbness or a burning sensation in the extremities can be sudden and severe. Currently, only two prescription medications are approved for treatment of DPN symptoms, though many more are routinely used in practice. Clinical trials suggest that commonly used therapies have similar efficacy with respect to pain relief. However, side effects are common and little is known about the relative efficacy of these medications in addressing other patient-valued outcomes (e.g., quality of life). The goal of the proposal is to evaluate whether a clinical decision aid that includes information on patient treatment preferences can improve treatment persistence and outcomes that are important to patients.
Investigator: Adams, Alyce
Funder: Patient-Centered Outcomes Research Institute (PCORI)

The Diabetes Telephone Study; Design and challenges of a pragmatic cluster randomized trial to improve diabetic peripheral neuropathy treatment

Author(s): Adams AS; Bayliss EA; Schmittdiel JA; Altschuler A; Dyer W; Neugebauer R; Jaffe M; Young JD; Kim E; Grant RW; Diabetes Telephone Study Team
PubMed abstract

Effects of Eliminating Drug Caps on Racial Differences in Antidepressant Use Among Dual Enrollees With Diabetes and Depression

Author(s): Adams AS; Soumerai SB; Zhang F; Gilden D; Burns M; Huskamp HA; Trinacty C; Alegria M; LeCates RF; Griggs JJ; Ross-Degnan D; Madden JM
PubMed abstract

Changes in Use of Lipid-lowering Medications Among Black and White Dual Enrollees With Diabetes Transitioning From Medicaid to Medicare Part D Drug Coverage

Author(s): Adams AS; Madden JM; Zhang F; Soumerai SB; Gilden D; Griggs J; Trinacty CM; Bishop C; Ross-Degnan D
PubMed abstract

Health System Factors and Antihypertensive Adherence in a Racially and Ethnically Diverse Cohort of New Users

Author(s): Adams AS; Uratsu C; Dyer W; Magid D; O'Connor P; Beck A; Butler M; Ho PM; Schmittdiel JA
PubMed abstract

Medication adherence and racial differences in A1C control

Author(s): Adams AS; Trinacty CM; Zhang F; Kleinman K; Grant RW; Meigs JB; Soumerai SB; Ross-Degnan D
PubMed abstract

Effect of Out-of-Pocket Cost on Medication Initiation, Adherence and Persistence among Patients with Type 2 Diabetes: The Diabetes Study of Northern California (DISTANCE).

Author(s): Karter AJ; Parker MM; Solomon MD; Lyles CR; Adams AS; Moffet HH; Reed ME;
PubMed abstract

Effect of Out-of-Pocket Cost on Medication Initiation, Adherence, and Persistence among Patients with Type 2 Diabetes: The Diabetes Study of Northern California (DISTANCE)

Author(s): Karter AJ; Parker MM; Solomon MD; Lyles CR; Adams AS; Moffet HH; Reed ME
PubMed abstract

Population Health Management for Diabetes: Health Care System-Level Approaches for Improving Quality and Addressing Disparities

Author(s): Schmittdiel JA; Gopalan A; Lin MW; Banerjee S; Chau CV; Adams AS
PubMed abstract

Predicting Adherence and Persistence with Oral Bisphosphonate Therapy in an Integrated Health Care Delivery System

Author(s): Hui RL; Adams AL; Niu F; Ettinger B; Yi DK; Chandra M; Lo JC
PubMed abstract

Association of the Affordable Care Act With Smoking and Tobacco Treatment Utilization Among Adults Newly Enrolled in Health Care

Author(s): Young-Wolff KC; Klebaner D; Campbell CI; Weisner C; Satre DD; Adams AS
PubMed abstract

Overcoming barriers to diabetic polyneuropathy management in primary care

Author(s): Adams AS; Callaghan B; Grant RW
PubMed abstract

A Learning Behavioral Health Care System; Opportunities to Enhance Research

Author(s): Stein BD; Adams AS; Chambers DA
PubMed abstract

Improved Perinatal Depression Screening, Treatment, and Outcomes With a Universal Obstetric Program

Author(s): Avalos LA; Raine-Bennett T; Chen H; Adams AS; Flanagan T
PubMed abstract

The Diabetes Telephone Study; Design and challenges of a pragmatic cluster randomized trial to improve diabetic peripheral neuropathy treatment

Author(s): Adams AS; Bayliss EA; Schmittdiel JA; Altschuler A; Dyer W; Neugebauer R; Jaffe M; Young JD; Kim E; Grant RW; Diabetes Telephone Study Team
PubMed abstract

Pre-visit prioritization for complex patients with Diabetes; Randomized Trial Design and Implementation within an Integrated Health Care system

Author(s): Grant RW; Uratsu CS; Hansen KR; Altschuler A; Kim E; Fireman B; Adams AS; Schmittdiel JA; Heisler M
PubMed abstract

An algorithm to identify medication nonpersistence using electronic pharmacy databases

Author(s): Parker MM; Moffet HH; Adams A; Karter AJ
PubMed abstract

Patient reported outcomes for diabetic peripheral neuropathy

Author(s): Bredfeldt C; Altschuler A; Adams AS; Portz JD; Bayliss EA
PubMed abstract

Ethnic Differences in Geriatric Conditions and Diabetes Complications Among Older, Insured Adults With Diabetes; The Diabetes and Aging Study

Author(s): Karter AJ; Laiteerapong N; Chin MH; Moffet HH; Parker MM; Sudore R; Adams AS; Schillinger D; Adler NS; Whitmer RA; Piette JD; Huang ES
PubMed abstract

Impact of a Pharmacy Benefit Change on New Use of Mail Order Pharmacy among Diabetes Patients; The Diabetes Study of Northern California (DISTANCE)

Author(s): Karter AJ; Parker MM; Duru OK; Schillinger D; Adler NE; Moffet HH; Adams AS; Chan J; Herman WH; Schmittdiel JA
PubMed abstract

Effects of Eliminating Drug Caps on Racial Differences in Antidepressant Use Among Dual Enrollees With Diabetes and Depression

Author(s): Adams AS; Soumerai SB; Zhang F; Gilden D; Burns M; Huskamp HA; Trinacty C; Alegria M; LeCates RF; Griggs JJ; Ross-Degnan D; Madden JM
PubMed abstract

Diabetes care and outcomes for American Indians and Alaska natives in commercial integrated delivery systems; a SUrveillance, PREvention, and ManagEment of Diabetes Mellitus (SUPREME-DM) Study

Author(s): Schmittdiel JA; Steiner JF; Adams AS; Dyer W; Beals J; Henderson WG; Desai J; Morales LS; Nichols GA; Lawrence JM; Waitzfelder B; Butler MG; Pathak RD; Hamman RF; Manson SM
PubMed abstract

Changes in Use of Lipid-lowering Medications Among Black and White Dual Enrollees With Diabetes Transitioning From Medicaid to Medicare Part D Drug Coverage

Author(s): Adams AS; Madden JM; Zhang F; Soumerai SB; Gilden D; Griggs J; Trinacty CM; Bishop C; Ross-Degnan D
PubMed abstract

Associations Between Antidepressant Adherence and Shared Decision-Making, Patient-Provider Trust, and Communication Among Adults with Diabetes; Diabetes Study of Northern California (DISTANCE)

Author(s): Bauer AM; Parker MM; Schillinger D; Katon W; Adler N; Adams AS; Moffet HH; Karter AJ
PubMed abstract

Initial Persistence With Antihypertensive Therapies Is Associated With Depression Treatment Persistence, But Not Depression

Author(s): Schmittdiel JA; Dyer W; Uratsu C; Magid DJ; O'Connor PJ; Beck A; Butler M; Ho MP; Vazquez-Benitez G; Adams AS
PubMed abstract

Effects of Medicare Part D on Guideline-Concordant Pharmacotherapy for Bipolar I Disorder Among Dual Beneficiaries

Author(s): Burns ME; Busch AB; Madden JM; Le Cates RF; Zhang F; Adams AS; Ross-Degnan D; Soumerai SB; Huskamp HA
PubMed abstract

Establishing visit priorities for complex patients; A summary of the literature and conceptual model to guide innovative interventions

Author(s): Grant RW; Adams AS; Bayliss EA; Heisler M
PubMed abstract

Differences in the clinical recognition of depression in diabetes patients; the diabetes study of northern california (DISTANCE)

Author(s): Hudson DL; Karter AJ; Fernandez A; Parker M; Adams AS; Schillinger D; Moffet HH; Zhou J; Adler NE
PubMed abstract

Health Literacy and Antidepressant Medication Adherence Among Adults with Diabetes; The Diabetes Study of Northern California (DISTANCE)

Author(s): Bauer AM; Schillinger D; Parker MM; Katon W; Adler N; Adams AS; Moffet HH; Karter AJ
PubMed abstract

The top patient safety strategies that can be encouraged for adoption now

Author(s): Shekelle PG; Pronovost PJ; Wachter RM; McDonald KM; Schoelles K; Dy SM; Shojania K; Reston JT; Adams AS; Angood PB; Bates DW; Bickman L; Carayon P; Donaldson L; Duan N; Farley DO; Greenhalgh T; Haughom JL; Lake E; Lilford R; Lohr KN; Meyer GS; Miller MR; Neuhauser DV; Ryan G; Saint S; Shortell SM; Stevens DP; Walshe K
PubMed abstract

Health System Factors and Antihypertensive Adherence in a Racially and Ethnically Diverse Cohort of New Users

Author(s): Adams AS; Uratsu C; Dyer W; Magid D; O'Connor P; Beck A; Butler M; Ho PM; Schmittdiel JA
PubMed abstract

Health-Plan and Employer-Based Wellness Programs to Reduce Diabetes Risk; The Kaiser Permanente Northern California NEXT-D Study

Author(s): Schmittdiel JA; Brown SD; Neugebauer R; Adams SR; Adams AS; Wiley D; Ferrara A
PubMed abstract

Elevated Rates of Diabetes in Pacific Islanders and Asian Subgroups; The Diabetes Study of Northern California (DISTANCE)

Author(s): Karter AJ; Schillinger D; Adams AS; Moffet HH; Liu J; Adler NE; Kanaya AM
PubMed abstract

Symptom Burden of Adults with Type 2 Diabetes Across the Disease Course; Diabetes & Aging Study

Author(s): Sudore RL; Karter AJ; Huang ES; Moffet HH; Laiteerapong N; Schenker Y; Adams A; Whitmer RA; Liu JY; Miao Y; John PM; Schillinger D
PubMed abstract

Medicare part d and changes in prescription drug use and cost burden; national estimates for the medicare population, 2000 to 2007

Author(s): Briesacher BA; Zhao Y; Madden JM; Zhang F; Adams AS; Tjia J; Ross-Degnan D; Gurwitz JH; Soumerai SB
PubMed abstract

Racial and ethnic disparities in postpartum depression care among low-income women

Author(s): Kozhimannil KB; Trinacty CM; Busch AB; Huskamp HA; Adams AS
PubMed abstract

Advancing the science of patient safety

Author(s): Shekelle PG; Pronovost PJ; Wachter RM; Taylor SL; Dy SM; Foy R; Hempel S; McDonald KM; Ovretveit J; Rubenstein LV; Adams AS; Angood PB; Bates DW; Bickman L; Carayon P; Donaldson L; Duan N; Farley DO; Greenhalgh T; Haughom J; Lake ET; Lilford R; Lohr KN; Meyer GS; Miller MR; Neuhauser DV; Ryan G; Saint S; Shojania KG; Shortell SM; Stevens DP; Walshe K
PubMed abstract

Adherence to laboratory test requests by patients with diabetes; the Diabetes Study of Northern California (DISTANCE)

Author(s): Moffet HH; Parker MM; Sarkar U; Schillinger D; Fernandez A; Adler NE; Adams AS; Karter AJ
PubMed abstract

Heterogeneity of diabetes outcomes among asians and pacific islanders in the US; the diabetes study of northern california (DISTANCE)

Author(s): Kanaya AM; Adler N; Moffet HH; Liu J; Schillinger D; Adams A; Ahmed AT; Karter AJ
PubMed abstract

New Jersey's efforts to improve postpartum depression care did not change treatment patterns for women on medicaid

Author(s): Kozhimannil KB; Adams AS; Soumerai SB; Busch AB; Huskamp HA
PubMed abstract

Association between prior authorization for medications and health service use by Medicaid patients with bipolar disorder

Author(s): Lu CY; Adams AS; Ross-Degnan D; Zhang F; Zhang Y; Salzman C; Soumerai SB
PubMed abstract

Impact of prior authorization on the use and costs of lipid-lowering medications among Michigan and Indiana dual enrollees in Medicaid and Medicare; results of a longitudinal, population-based study

Author(s): Lu CY; Law MR; Soumerai SB; Graves AJ; LeCates RF; Zhang F; Ross-Degnan D; Adams AS
PubMed abstract

Use of well-child visits in high-deductible health plans

Author(s): Galbraith AA; Ross-Degnan D; Soumerai SB; Abrams AM; Kleinman K; Rosenthal MB; Wharam JF; Adams AS; Miroshnik I; Lieu TA
PubMed abstract

Primary non-adherence to prescribed medications

Author(s): Karter AJ; Parker MM; Adams AS; Moffet HH; Schmittdiel JA; Ahmed AT; Selby JV
PubMed abstract

Impact of two Medicaid prior-authorization policies on antihypertensive use and costs among Michigan and Indiana residents dually enrolled in Medicaid and Medicare; results of a longitudinal, population-based study

Author(s): Law MR; Lu CY; Soumerai SB; Graves AJ; LeCates RF; Zhang F; Ross-Degnan D; Adams AS
PubMed abstract

Unintended impacts of a Medicaid prior authorization policy on access to medications for bipolar illness

Author(s): Lu CY; Soumerai SB; Ross-Degnan D; Zhang F; Adams AS
PubMed abstract

A new measure of medication affordability

Author(s): Briesacher B; Ross-Degnan D; Adams A; Wagner A; Gurwitz J; Soumerai S
PubMed abstract

The population-level impacts of a national health insurance program and franchise midwife clinics on achievement of prenatal and delivery care standards in the Philippines

Author(s): Kozhimannil KB; Valera MR; Adams AS; Ross-Degnan D
PubMed abstract

Prior authorization for antidepressants in Medicaid; effects among disabled dual enrollees

Author(s): Adams AS; Zhang F; LeCates RF; Graves AJ; Ross-Degnan D; Gilden D; McLaughlin TJ; Lu C; Trinacty CM; Soumerai SB
PubMed abstract

Racial differences in long-term adherence to oral antidiabetic drug therapy; a longitudinal cohort study

Author(s): Trinacty CM; Adams AS; Soumerai SB; Zhang F; Meigs JB; Piette JD; Ross-Degnan D
PubMed abstract

Medication adherence and racial differences in A1C control

Author(s): Adams AS; Trinacty CM; Zhang F; Kleinman K; Grant RW; Meigs JB; Soumerai SB; Ross-Degnan D
PubMed abstract

Cost-related medication nonadherence and spending on basic needs following implementation of Medicare Part D

Author(s): Madden JM; Graves AJ; Zhang F; Adams AS; Briesacher BA; Ross-Degnan D; Gurwitz JH; Pierre-Jacques M; Safran DG; Adler GS; Soumerai SB
PubMed abstract