Sign In

Alyce S. Adams, PhD

People

Kaiser Permanente Division of Research
2000 Broadway
Oakland, CA 94612

(510) 891-5921 (phone)
alyce.s.adams@kp.org
Kaiser Permanente Researcher Profiles


Dr. Adams' work has focused on the determinants of suboptimal use of potentially beneficial health care services among disparities populations, including racial differences in medication adherence and the impact of changes in health policy on access to high quality health services and health outcomes for vulnerable patients. Dr. Adams is a member of the Kaiser Permanente Disparities Working Group and the Advisory Committee on Quality for the California Health Families Program.

Current Position(s):

  • Research Scientist III, Division of Research, Kaiser Permanente Northern California

Section Affiliations:

Primary Research Interests:

  • Healthcare Disparities/Vulnerable Populations
  • Health Services and Policy Research

    Balancing Treatment Outcomes and Medication Burden among Patients with Symptomatic Diabetic Peripheral Neuropathy

    This project is a continuation of a study we recently conducted to identify and prioritize treatment outcomes of relevance to patients with diabetic peripheral neuropathy (DPN). DPN affects 30% to 50% of all adults with diabetes and symptoms such as pain, tingling, numbness or a burning sensation in the extremities can be sudden and severe. Currently, only two prescription medications are approved for treatment of DPN symptoms, though many more are routinely used in practice. Clinical trials suggest that commonly used therapies have similar efficacy with respect to pain relief. However, side effects are common and little is known about the relative efficacy of these medications in addressing other patient-valued outcomes (e.g., quality of life). The goal of the proposal is to evaluate whether a clinical decision aid that includes information on patient treatment preferences can improve treatment persistence and outcomes that are important to patients.
    Investigator: Adams, Alyce
    Funder: Patient-Centered Outcomes Research Institute (PCORI)

    The Diabetes Telephone Study; Design and challenges of a pragmatic cluster randomized trial to improve diabetic peripheral neuropathy treatment

    Author(s): Adams AS; Bayliss EA; Schmittdiel JA; Altschuler A; Dyer W; Neugebauer R; Jaffe M; Young JD; Kim E; Grant RW; Diabetes Telephone Study Team
    PubMed abstract

    Effects of Eliminating Drug Caps on Racial Differences in Antidepressant Use Among Dual Enrollees With Diabetes and Depression

    Author(s): Adams AS; Soumerai SB; Zhang F; Gilden D; Burns M; Huskamp HA; Trinacty C; Alegria M; LeCates RF; Griggs JJ; Ross-Degnan D; Madden JM
    PubMed abstract

    Changes in Use of Lipid-lowering Medications Among Black and White Dual Enrollees With Diabetes Transitioning From Medicaid to Medicare Part D Drug Coverage

    Author(s): Adams AS; Madden JM; Zhang F; Soumerai SB; Gilden D; Griggs J; Trinacty CM; Bishop C; Ross-Degnan D
    PubMed abstract

    Health System Factors and Antihypertensive Adherence in a Racially and Ethnically Diverse Cohort of New Users

    Author(s): Adams AS; Uratsu C; Dyer W; Magid D; O'Connor P; Beck A; Butler M; Ho PM; Schmittdiel JA
    PubMed abstract

    Medication adherence and racial differences in A1C control

    Author(s): Adams AS; Trinacty CM; Zhang F; Kleinman K; Grant RW; Meigs JB; Soumerai SB; Ross-Degnan D
    PubMed abstract

    Effect of Out-of-Pocket Cost on Medication Initiation, Adherence and Persistence among Patients with Type 2 Diabetes: The Diabetes Study of Northern California (DISTANCE).

    Author(s): Karter AJ; Parker MM; Solomon MD; Lyles CR; Adams AS; Moffet HH; Reed ME;
    PubMed abstract

    Effect of Out-of-Pocket Cost on Medication Initiation, Adherence, and Persistence among Patients with Type 2 Diabetes: The Diabetes Study of Northern California (DISTANCE)

    Author(s): Karter AJ; Parker MM; Solomon MD; Lyles CR; Adams AS; Moffet HH; Reed ME
    PubMed abstract

    Population Health Management for Diabetes: Health Care System-Level Approaches for Improving Quality and Addressing Disparities

    Author(s): Schmittdiel JA; Gopalan A; Lin MW; Banerjee S; Chau CV; Adams AS
    PubMed abstract

    Predicting Adherence and Persistence with Oral Bisphosphonate Therapy in an Integrated Health Care Delivery System

    Author(s): Hui RL; Adams AL; Niu F; Ettinger B; Yi DK; Chandra M; Lo JC
    PubMed abstract

    Association of the Affordable Care Act With Smoking and Tobacco Treatment Utilization Among Adults Newly Enrolled in Health Care

    Author(s): Young-Wolff KC; Klebaner D; Campbell CI; Weisner C; Satre DD; Adams AS
    PubMed abstract

    Overcoming barriers to diabetic polyneuropathy management in primary care

    Author(s): Adams AS; Callaghan B; Grant RW
    PubMed abstract

    A Learning Behavioral Health Care System; Opportunities to Enhance Research

    Author(s): Stein BD; Adams AS; Chambers DA
    PubMed abstract

    Improved Perinatal Depression Screening, Treatment, and Outcomes With a Universal Obstetric Program

    Author(s): Avalos LA; Raine-Bennett T; Chen H; Adams AS; Flanagan T
    PubMed abstract

    The Diabetes Telephone Study; Design and challenges of a pragmatic cluster randomized trial to improve diabetic peripheral neuropathy treatment

    Author(s): Adams AS; Bayliss EA; Schmittdiel JA; Altschuler A; Dyer W; Neugebauer R; Jaffe M; Young JD; Kim E; Grant RW; Diabetes Telephone Study Team
    PubMed abstract

    Pre-visit prioritization for complex patients with Diabetes; Randomized Trial Design and Implementation within an Integrated Health Care system

    Author(s): Grant RW; Uratsu CS; Hansen KR; Altschuler A; Kim E; Fireman B; Adams AS; Schmittdiel JA; Heisler M
    PubMed abstract

    An algorithm to identify medication nonpersistence using electronic pharmacy databases

    Author(s): Parker MM; Moffet HH; Adams A; Karter AJ
    PubMed abstract

    Patient reported outcomes for diabetic peripheral neuropathy

    Author(s): Bredfeldt C; Altschuler A; Adams AS; Portz JD; Bayliss EA
    PubMed abstract

    Ethnic Differences in Geriatric Conditions and Diabetes Complications Among Older, Insured Adults With Diabetes; The Diabetes and Aging Study

    Author(s): Karter AJ; Laiteerapong N; Chin MH; Moffet HH; Parker MM; Sudore R; Adams AS; Schillinger D; Adler NS; Whitmer RA; Piette JD; Huang ES
    PubMed abstract

    Impact of a Pharmacy Benefit Change on New Use of Mail Order Pharmacy among Diabetes Patients; The Diabetes Study of Northern California (DISTANCE)

    Author(s): Karter AJ; Parker MM; Duru OK; Schillinger D; Adler NE; Moffet HH; Adams AS; Chan J; Herman WH; Schmittdiel JA
    PubMed abstract

    Effects of Eliminating Drug Caps on Racial Differences in Antidepressant Use Among Dual Enrollees With Diabetes and Depression

    Author(s): Adams AS; Soumerai SB; Zhang F; Gilden D; Burns M; Huskamp HA; Trinacty C; Alegria M; LeCates RF; Griggs JJ; Ross-Degnan D; Madden JM
    PubMed abstract

    Diabetes care and outcomes for American Indians and Alaska natives in commercial integrated delivery systems; a SUrveillance, PREvention, and ManagEment of Diabetes Mellitus (SUPREME-DM) Study

    Author(s): Schmittdiel JA; Steiner JF; Adams AS; Dyer W; Beals J; Henderson WG; Desai J; Morales LS; Nichols GA; Lawrence JM; Waitzfelder B; Butler MG; Pathak RD; Hamman RF; Manson SM
    PubMed abstract

    Changes in Use of Lipid-lowering Medications Among Black and White Dual Enrollees With Diabetes Transitioning From Medicaid to Medicare Part D Drug Coverage

    Author(s): Adams AS; Madden JM; Zhang F; Soumerai SB; Gilden D; Griggs J; Trinacty CM; Bishop C; Ross-Degnan D
    PubMed abstract

    Associations Between Antidepressant Adherence and Shared Decision-Making, Patient-Provider Trust, and Communication Among Adults with Diabetes; Diabetes Study of Northern California (DISTANCE)

    Author(s): Bauer AM; Parker MM; Schillinger D; Katon W; Adler N; Adams AS; Moffet HH; Karter AJ
    PubMed abstract

    Initial Persistence With Antihypertensive Therapies Is Associated With Depression Treatment Persistence, But Not Depression

    Author(s): Schmittdiel JA; Dyer W; Uratsu C; Magid DJ; O'Connor PJ; Beck A; Butler M; Ho MP; Vazquez-Benitez G; Adams AS
    PubMed abstract

    Effects of Medicare Part D on Guideline-Concordant Pharmacotherapy for Bipolar I Disorder Among Dual Beneficiaries

    Author(s): Burns ME; Busch AB; Madden JM; Le Cates RF; Zhang F; Adams AS; Ross-Degnan D; Soumerai SB; Huskamp HA
    PubMed abstract

    Establishing visit priorities for complex patients; A summary of the literature and conceptual model to guide innovative interventions

    Author(s): Grant RW; Adams AS; Bayliss EA; Heisler M
    PubMed abstract

    Differences in the clinical recognition of depression in diabetes patients; the diabetes study of northern california (DISTANCE)

    Author(s): Hudson DL; Karter AJ; Fernandez A; Parker M; Adams AS; Schillinger D; Moffet HH; Zhou J; Adler NE
    PubMed abstract

    Health Literacy and Antidepressant Medication Adherence Among Adults with Diabetes; The Diabetes Study of Northern California (DISTANCE)

    Author(s): Bauer AM; Schillinger D; Parker MM; Katon W; Adler N; Adams AS; Moffet HH; Karter AJ
    PubMed abstract

    The top patient safety strategies that can be encouraged for adoption now

    Author(s): Shekelle PG; Pronovost PJ; Wachter RM; McDonald KM; Schoelles K; Dy SM; Shojania K; Reston JT; Adams AS; Angood PB; Bates DW; Bickman L; Carayon P; Donaldson L; Duan N; Farley DO; Greenhalgh T; Haughom JL; Lake E; Lilford R; Lohr KN; Meyer GS; Miller MR; Neuhauser DV; Ryan G; Saint S; Shortell SM; Stevens DP; Walshe K
    PubMed abstract

    Health System Factors and Antihypertensive Adherence in a Racially and Ethnically Diverse Cohort of New Users

    Author(s): Adams AS; Uratsu C; Dyer W; Magid D; O'Connor P; Beck A; Butler M; Ho PM; Schmittdiel JA
    PubMed abstract

    Health-Plan and Employer-Based Wellness Programs to Reduce Diabetes Risk; The Kaiser Permanente Northern California NEXT-D Study

    Author(s): Schmittdiel JA; Brown SD; Neugebauer R; Adams SR; Adams AS; Wiley D; Ferrara A
    PubMed abstract

    Elevated Rates of Diabetes in Pacific Islanders and Asian Subgroups; The Diabetes Study of Northern California (DISTANCE)

    Author(s): Karter AJ; Schillinger D; Adams AS; Moffet HH; Liu J; Adler NE; Kanaya AM
    PubMed abstract

    Symptom Burden of Adults with Type 2 Diabetes Across the Disease Course; Diabetes & Aging Study

    Author(s): Sudore RL; Karter AJ; Huang ES; Moffet HH; Laiteerapong N; Schenker Y; Adams A; Whitmer RA; Liu JY; Miao Y; John PM; Schillinger D
    PubMed abstract

    Medicare part d and changes in prescription drug use and cost burden; national estimates for the medicare population, 2000 to 2007

    Author(s): Briesacher BA; Zhao Y; Madden JM; Zhang F; Adams AS; Tjia J; Ross-Degnan D; Gurwitz JH; Soumerai SB
    PubMed abstract

    Racial and ethnic disparities in postpartum depression care among low-income women

    Author(s): Kozhimannil KB; Trinacty CM; Busch AB; Huskamp HA; Adams AS
    PubMed abstract

    Advancing the science of patient safety

    Author(s): Shekelle PG; Pronovost PJ; Wachter RM; Taylor SL; Dy SM; Foy R; Hempel S; McDonald KM; Ovretveit J; Rubenstein LV; Adams AS; Angood PB; Bates DW; Bickman L; Carayon P; Donaldson L; Duan N; Farley DO; Greenhalgh T; Haughom J; Lake ET; Lilford R; Lohr KN; Meyer GS; Miller MR; Neuhauser DV; Ryan G; Saint S; Shojania KG; Shortell SM; Stevens DP; Walshe K
    PubMed abstract

    Adherence to laboratory test requests by patients with diabetes; the Diabetes Study of Northern California (DISTANCE)

    Author(s): Moffet HH; Parker MM; Sarkar U; Schillinger D; Fernandez A; Adler NE; Adams AS; Karter AJ
    PubMed abstract

    Heterogeneity of diabetes outcomes among asians and pacific islanders in the US; the diabetes study of northern california (DISTANCE)

    Author(s): Kanaya AM; Adler N; Moffet HH; Liu J; Schillinger D; Adams A; Ahmed AT; Karter AJ
    PubMed abstract

    New Jersey's efforts to improve postpartum depression care did not change treatment patterns for women on medicaid

    Author(s): Kozhimannil KB; Adams AS; Soumerai SB; Busch AB; Huskamp HA
    PubMed abstract

    Association between prior authorization for medications and health service use by Medicaid patients with bipolar disorder

    Author(s): Lu CY; Adams AS; Ross-Degnan D; Zhang F; Zhang Y; Salzman C; Soumerai SB
    PubMed abstract

    Impact of prior authorization on the use and costs of lipid-lowering medications among Michigan and Indiana dual enrollees in Medicaid and Medicare; results of a longitudinal, population-based study

    Author(s): Lu CY; Law MR; Soumerai SB; Graves AJ; LeCates RF; Zhang F; Ross-Degnan D; Adams AS
    PubMed abstract

    Use of well-child visits in high-deductible health plans

    Author(s): Galbraith AA; Ross-Degnan D; Soumerai SB; Abrams AM; Kleinman K; Rosenthal MB; Wharam JF; Adams AS; Miroshnik I; Lieu TA
    PubMed abstract

    Primary non-adherence to prescribed medications

    Author(s): Karter AJ; Parker MM; Adams AS; Moffet HH; Schmittdiel JA; Ahmed AT; Selby JV
    PubMed abstract

    Impact of two Medicaid prior-authorization policies on antihypertensive use and costs among Michigan and Indiana residents dually enrolled in Medicaid and Medicare; results of a longitudinal, population-based study

    Author(s): Law MR; Lu CY; Soumerai SB; Graves AJ; LeCates RF; Zhang F; Ross-Degnan D; Adams AS
    PubMed abstract

    Unintended impacts of a Medicaid prior authorization policy on access to medications for bipolar illness

    Author(s): Lu CY; Soumerai SB; Ross-Degnan D; Zhang F; Adams AS
    PubMed abstract

    A new measure of medication affordability

    Author(s): Briesacher B; Ross-Degnan D; Adams A; Wagner A; Gurwitz J; Soumerai S
    PubMed abstract

    The population-level impacts of a national health insurance program and franchise midwife clinics on achievement of prenatal and delivery care standards in the Philippines

    Author(s): Kozhimannil KB; Valera MR; Adams AS; Ross-Degnan D
    PubMed abstract

    Prior authorization for antidepressants in Medicaid; effects among disabled dual enrollees

    Author(s): Adams AS; Zhang F; LeCates RF; Graves AJ; Ross-Degnan D; Gilden D; McLaughlin TJ; Lu C; Trinacty CM; Soumerai SB
    PubMed abstract

    Racial differences in long-term adherence to oral antidiabetic drug therapy; a longitudinal cohort study

    Author(s): Trinacty CM; Adams AS; Soumerai SB; Zhang F; Meigs JB; Piette JD; Ross-Degnan D
    PubMed abstract

    Medication adherence and racial differences in A1C control

    Author(s): Adams AS; Trinacty CM; Zhang F; Kleinman K; Grant RW; Meigs JB; Soumerai SB; Ross-Degnan D
    PubMed abstract

    Cost-related medication nonadherence and spending on basic needs following implementation of Medicare Part D

    Author(s): Madden JM; Graves AJ; Zhang F; Adams AS; Briesacher BA; Ross-Degnan D; Gurwitz JH; Pierre-Jacques M; Safran DG; Adler GS; Soumerai SB
    PubMed abstract