Mary Anne Armstrong , MA

maryanne.armstrong@kp.org

Mary Anne Armstrong, MA, is a biostatistician and research scientist at the Kaiser Permanente Northern California Division of Research, as well as managing director of special projects. Ms. Armstrong earned her master’s degree in statistics from the University of California, Berkeley. She has been with the Division of Research since 1980, where she has worked in a wide variety of research areas, including alcohol and health, perinatal substance abuse, and neonatology.

Ms. Armstrong is the chair of the Division of Research Local Research Committee, a member of the Northern California Central Research Committee. She is director of the Division of Research Biostatistical Consulting Unit, and provides statistical consultation to members of The Permanente Medical Group in Northern California. Ms. Armstrong has authored or co-authored more than 85 peer-reviewed scientific publications on a wide-variety of topics, including the relation of alcohol use to blood pressure, coronary disease, and stroke; utilization of health services before and after alcohol abuse treatment; neonatal assisted ventilation; and women’s health.

Current Positions

Biostatistician and Managing Director of Special Projects, Kaiser Permanente Division of Research
Director, Division of Research Biostatistical Consulting Unit
Vice Chair, KPNC Central Research Committee
Local Research Chair, Kaiser Permanente Division of Research

Section Affiliations

Primary Research Interests

Biostatistics
Substance abuse and pregnancy
Fetal Alcohol Syndrome
Women’s health
Perinatal health services research

Studies

Understanding the risk of ectopic pregnancies among people seeking abortion: a retrospective case control study

This study aims to assess the incidence of ectopic pregnancy among people wanting pregnancy compared to people seeking abortion. The specific research questions are: Are people seeking abortion at lower risk of experiencing an ectopic pregnancy compared to people not seeking abortion? What are the unique risk factors for experiencing an ectopic pregnancy among people seeking abortion? How do people seeking abortion who are eventually diagnosed with ectopic pregnancies initially present for care? We will conduct a case-control study using a retrospective review of electronic health records of approximately 2,200 randomly chosen cases of ectopic pregnancies and a comparison group of 1,100 randomly chosen intrauterine pregnancies.

Investigator: Armstrong, Mary Anne

Funder: Fidelity Charitable

Study on the Association of Uterine Perforation and IUD expulsion With Breastfeeding Status at the Time of IUD insertion and Postpartum Timing of IUD Insertion in Electronic Medical Record Databases – A Post-marketing Requirement for Mirena

The Food and Drug Administration (FDA) has required Bayer AG to conduct a post-marketing study in the U.S. to determine the incidence of uterine perforation and IUD expulsion by type of intrauterine device (IUD) used. The goal of this study is to quantify the risk of uterine perforation and IUD expulsion by: (1) breastfeeding status at the time of IUD insertion, (2) time periods postpartum when the IUD was inserted (e.g., 6 weeks or less, after 6 weeks and up to 14 weeks, more than 14 weeks and up to 52 weeks, or more than 52 weeks), and (3) type of IUD.

Investigator: Armstrong, Mary Anne

Funder: Bayer AG

Risk of Uterine Perforation among Women Using different types of IUDs and the Association with Timing of Insertion and Breastfeeding

The goal of the study is to compare the incidence of uterine perforation within 12 months after IUD insertion between: (1) postpartum insertions within 12 months of delivery (with breastfeeding status), (2) post abortion or pregnancy loss IUD insertions and (3) interval IUD insertions not associated with a pregnancy, and to determine if IUD insertion immediately postpartum and/or breastfeeding are associated with an increased risk of perforation.

Investigator: Armstrong, Mary Anne

Funder: Bayer AG

Publications

Association of Pregnancy Intentions With Substance Use During Early Pregnancy

Authors: Young-Wolff, Kelly C; Slama, Natalie; Sarovar, Varada; Conway, Amy; Tucker, Lue-Yen; Goler, Nancy; Terplan, Mishka; Ansley, Deborah; Adams, Sara R; Armstrong, Mary Anne

J Addict Med. 2022 Jan-Feb 01;16(1):118-121.

Mary Anne Armstrong , MA

Current Positions

Section Affiliations

Primary Research Interests

Studies

Understanding the risk of ectopic pregnancies among people seeking abortion: a retrospective case control study

Study on the Association of Uterine Perforation and IUD expulsion With Breastfeeding Status at the Time of IUD insertion and Postpartum Timing of IUD Insertion in Electronic Medical Record Databases – A Post-marketing Requirement for Mirena

Risk of Uterine Perforation among Women Using different types of IUDs and the Association with Timing of Insertion and Breastfeeding

Publications

Association of Pregnancy Intentions With Substance Use During Early Pregnancy

Ectopic Pregnancy Prevention: Further Evidence of Benefits of Prescription Contraceptives

Design of the Association of Uterine Perforation and Expulsion of IUD (APEX-IUD) Study: A Multisite Retrospective Cohort Study

Development of a longitudinal two-biomarker algorithm for early detection of ovarian cancer in women with BRCA mutations

Identifying Ectopic Pregnancy in a Large Integrated Health Care Delivery System: Algorithm Validation

Trends and correlates of self-reported alcohol and nicotine use among women before and during pregnancy, 2009-2017

Feasibility, patient compliance and acceptability of ovarian cancer surveillance using two serum biomarkers and Risk of Ovarian Cancer Algorithm compared to standard ultrasound and CA 125 among women with BRCA mutations

Sexual function, menopausal symptoms, depression and cancer worry in women with BRCA mutations

Bone loss in women with BRCA1 and BRCA2 mutations

Diagnosis of sessile serrated adenoma after educational training in a large, community-based, integrated healthcare setting

Trends in Self-reported and Biochemically Tested Marijuana Use Among Pregnant Females in California From 2009-2016

Rates and Predictors of Vaccinations Among Inflammatory Bowel Disease Patients Receiving Anti-Tumor Necrosis Factor Agents

Are Health Plan Design and Prior Use of Long-Acting Reversible Contraception Associated with Pregnancy Intention?

Risk of cancer in Asian Americans: a Kaiser Permanente cohort study

Experience With Opportunistic Salpingectomy in a Large, Community-Based Health System in the United States

Alcohol Intake, Beverage Choice, and Cancer: A Cohort Study in a Large Kaiser Permanente Population

Prevalence and Neonatal Factors Associated with Autism Spectrum Disorders in Preterm Infants

Risk of Coronary Disease in South Asian Americans

The value of additional pathology comments indicating suspicion of adenocarcinoma among women diagnosed preoperatively with complex atypical endometrial hyperplasia

Postacute care and ischemic stroke mortality: findings from an integrated health care system in northern california

Coffee, caffeine, and risk of hospitalization for arrhythmias

Alcohol consumption and risk of hematologic malignancies

Complex atypical endometrial hyperplasia: the risk of unrecognized adenocarcinoma and value of preoperative dilation and curettage

Using drink size to talk about drinking during pregnancy: a randomized clinical trial of Early Start Plus

Documentation of contraception and pregnancy when prescribing potentially teratogenic medications for reproductive-age women

Using drink size to talk about drinking during pregnancy: Early start plus

Unstudied infants: outcomes of moderately premature infants in the neonatal intensive care unit

Rehospitalisation after birth hospitalisation: patterns among infants of all gestations

Risk of hemorrhagic stroke in Asian American ethnic groups

Wine, liquor, beer, and mortality

The early repolarization normal variant electrocardiogram: correlates and consequences

Traits of persons who drink decaffeinated coffee

The effect of coronary disease on changes in drinking in an older population

Perinatal substance abuse intervention in obstetric clinics decreases adverse neonatal outcomes

Alcohol drinking and risk of hemorrhagic stroke

Rehospitalization for neonatal dehydration: a nested case-control study

Utilization of health services among patients referred to an alcohol treatment program

Alcohol drinking and risk of hospitalization for ischemic stroke

Early Start: an obstetric clinic-based, perinatal substance abuse intervention program

Neonatal sepsis workups in infants >/=2000 grams at birth: A population-based study

Risk of pulmonary embolism and/or deep venous thrombosis in Asian-Americans

Neonatal assisted ventilation: predictors, frequency, and duration in a mature managed care organization

Sex-based differences in causes of hospitalization for coronary heart disease

Frequency of neonatal bilirubin testing and hyperbilirubinemia in a large health maintenance organization

Rehospitalization for respiratory syncytial virus among premature infants

Rehospitalization in the first two weeks after discharge from the neonatal intensive care unit

Alcohol consumption and utilization of health services in a health maintenance organization

Structured review of neonatal deaths in a managed care organisation

Cataract extraction. Risk factors in a health maintenance organization population under 60 years of age

Precursors of essential hypertension: body weight, alcohol and salt use, and parental history of hypertension