Lyndsay Avalos, PhD, MPH

People

Moderate Hypertension in Pregnancy: Safety and Effectiveness of Treatment

The aims of this study are to: 1. Estimate risks of adverse pregnancy outcomes after antihypertensive medication exposure compared to a) untreated chronic or gestational hypertension, and b) healthy pregnancies with neither hypertension nor treatment. We will study: a) Maternal outcomes including cesarean delivery, postpartum hemorrhage, pre-eclampsia, and ICU admission; and b) Neonatal outcomes including preterm birth, small-for-gestational age, intensive care unit (NICU) stay, congenital malformations, and perinatal death. 2.Examine how risks vary for different antihypertensive agents. 3.Examine how risks vary according to the degree of blood pressure control achieved during treatment. 4. Examine how risks vary by obesity, GDM status and race/ethnicity.
Investigator: Avalos, Lyndsay
Funder: National Institute of Child Health and Human Development

Impact of Folate, Obesity and Genetics on Maternal Depression

Research is desperately needed to inform safe and effective interventions for the prevention and treatment of maternal depression. An important first step to understanding whether nutrition may serve as an intervention and improve maternal mental health, is to elucidate the relationship between nutrition and depression during the peripartum period (during pregnancy and after). The aims of this study will address a gap in knowledge and provide insights into the relationship between nutrition and maternal depression which will take us a few steps closer to identifying whether dietary modifications or supplements may provide an inexpensive, easily modifiable intervention for the prevention of peripartum depression.
Investigator: Avalos, Lyndsay
Funder: National Institute of Mental Health

Climate Change and Health: Assessing the Risk of Preterm Delivery

The overall objective of this study is to examine the impact of climate change on the risk of preterm delivery (PTD) by using a case-crossover study design utilizing members of KPNC. In our first aim, we will assess the relationship between apparent temperature and PTD. Estimates will be adjusted for important air pollutants. In our second aim we will determine whether maternal factors (age, race/ethnicity and SES as measured by medicaid status) impact the relationship between apparent temperature and preterm delivery. Finally, we will explore whether additional maternal factors may impact the the relationships in the first aim. These additional factors include hypertension, smoking, alcohol use, medication use, gestational diabetes, depression, and pre-pregnancy BMI.
Investigator: Avalos, Lyndsay
Funder: National Institute of Environmental Health Sciences

Improved Perinatal Depression Screening, Treatment, and Outcomes With a Universal Obstetric Program

Author(s): Avalos LA; Raine-Bennett T; Chen H; Adams AS; Flanagan T

Obstet Gynecol. 2016 May;127(5):917-25.

PubMed abstract

A systematic review to calculate background miscarriage rates using life table analysis

Author(s): Ammon Avalos L; Galindo C; Li DK

Birth Defects Res A Clin Mol Teratol. 2012 Jun;94(6):417-23. Epub 2012 Apr 18.

PubMed abstract

Do multivitamin supplements modify the relationship between prenatal alcohol intake and miscarriage?

Author(s): Ammon Avalos L; Kaskutas LA; Block G; Li DK

Am J Obstet Gynecol. 2009 Dec;201(6):563.e1-9. Epub 2009 Oct 20.

PubMed abstract

Preventing Perinatal Depression to Improve Maternal and Child Health-a Health Care Imperative

Author(s): Avalos LA; Flanagan T; Li DK

JAMA Pediatr. 2019 Feb 12.

PubMed abstract

Trends in marijuana use among pregnant women with and without nausea and vomiting in pregnancy, 2009-2016

Author(s): Young-Wolff KC; Sarovar V; Tucker LY; Avalos LA; Alexeeff S; Conway A; Armstrong MA; Weisner C; Campbell CI; Goler N

Drug Alcohol Depend. 2019 Mar 01;196:66-70. Epub 2019-01-18.

PubMed abstract

Association of Nausea and Vomiting in Pregnancy With Prenatal Marijuana Use

Author(s): Young-Wolff KC; Sarovar V; Tucker LY; Avalos LA; Conway A; Armstrong MA; Goler N

JAMA Intern Med. 2018 Aug 20.

PubMed abstract

Understanding periviable birth: A microeconomic alternative to the dysregulation narrative

Author(s): Catalano R; Bruckner T; Avalos LA; Stewart H; Karasek D; Kariv S; Gemmill A; Saxton K; Casey J

Soc Sci Med. 2017 Dec 12.

PubMed abstract

Intimate Partner Violence, Smoking, and Pregnancy: What Can We Do to Help?

Author(s): Young-Wolff KC; McCaw B; Avalos LA

J Womens Health (Larchmt). 2017 Sep 22.

PubMed abstract

Predictors of Breastfeeding Initiation and Maintenance in an Integrated Healthcare Setting

Author(s): Henninger ML; Irving SA; Kauffman TL; Kurosky SK; Rompala K; Thompson MG; Sokolow LZ; Avalos LA; Ball SW; Shifflett P; Naleway AL; Pregnancy and Influenza Project Workgroup

J Hum Lact. 2017 May;33(2):256-266. Epub 2017-03-23.

PubMed abstract

The impact of high apparent temperature on spontaneous preterm delivery: a case-crossover study

Author(s): Avalos LA; Chen H; Li DK; Basu R

Environ Health. 2017 Feb 01;16(1):5. Epub 2017-02-01.

PubMed abstract

The impact of maternal factors on the association between temperature and preterm delivery

Author(s): Basu R; Chen H; Li DK; Avalos LA

Environ Res. 2017 Jan 02;154:109-114. Epub 2017-01-02.

PubMed abstract

The Kaiser Permanente Northern California research program on genes, environment, and health (RPGEH) pregnancy cohort; study design, methodology and baseline characteristics.

Author(s): Hedderson MM; Ferrara A; Avalos LA; Van den Eeden SK; Gunderson EP; Li DK; Altschuler A; Woo S; Rowell S; Choudhary V; Xu F; Flanagan T; Schaefer C; Croen LA;

​BMC Pregnancy Childbirth. 2016 Nov 29;16(1):381.

PubMed abstract

Improved Perinatal Depression Screening, Treatment, and Outcomes With a Universal Obstetric Program

Author(s): Avalos LA; Raine-Bennett T; Chen H; Adams AS; Flanagan T

Obstet Gynecol. 2016 May;127(5):917-25.

PubMed abstract

Formal and informal substance use treatment utilization and alcohol abstinence over seven years: Is the relationship different for blacks and whites?

Author(s): Avalos LA; Mulia N

Drug Alcohol Depend. 2012 Feb 1;121(1-2):73-80. Epub 2011 Sep 21.

PubMed abstract

Factors Associated with Seasonal Influenza Vaccination in Pregnant Women

Author(s): Henninger ML; Irving SA; Thompson M; Avalos LA; Ball SW; Shifflett P; Naleway AL

J Womens Health (Larchmt). 2015 Apr 15.

PubMed abstract

Antidepressant medication use, depression, and the risk of preeclampsia

Author(s): Avalos LA; Chen H; Li DK

CNS Spectr. 2015 Feb;20(1):39-47.

PubMed abstract

The Association Between Influenza Vaccination and Other Preventative Health Behaviors in a Cohort of Pregnant Women

Author(s): Scheminske M; Henninger M; Irving SA; Thompson M; Williams J; Shifflett P; Ball SW; Avalos LA; Naleway AL; for The Pregnancy and Influenza Project Workgroup

Health Educ Behav. 2014 Dec 12.

PubMed abstract

Genital herpes and its treatment in relation to preterm delivery

Author(s): Li DK; Raebel MA; Cheetham TC; Hansen C; Avalos L; Chen H; Davis R

Am J Epidemiol. 2014 Dec 1;180(11):1109-17. Epub 2014-11-12.

PubMed abstract

Feasibility and acceptability of a novel, computerized screening and brief intervention (SBI) for alcohol and sweetened beverage use in pregnancy

Author(s): Nayak MB; Korcha RA; Kaskustas LA; Avalos LA

BMC Pregnancy Childbirth. 2014;14:379. Epub 2014-11-25.

PubMed abstract

Trends in Elective Labor Induction for Six United States Health Plans, 2001-2007

Author(s): Dublin S; Johnson KE; Walker RL; Avalos LA; Andrade SE; Beaton SJ; Davis RL; Herrinton LJ; Pawloski PA; Raebel MA; Smith DH; Toh S; Caughey AB

J Womens Health (Larchmt). 2014 Nov;23(11):904-11. Epub 2014-10-20.

PubMed abstract

Volume and Type of Alcohol During Early Pregnancy and the Risk of Miscarriage

Author(s): Avalos LA; Roberts SC; Kaskutas LA; Block G; Li DK

Subst Use Misuse. 2014 Sep;49(11):1437-45. Epub 2014-05-08.

PubMed abstract

The Prevalence and Trends of Antiviral Medication Use During Pregnancy in the US: A Population-Based Study of 664,297 Deliveries in 2001-2007

Author(s): Avalos LA; Chen H; Yang C; Andrade SE; Cooper WO; Cheetham CT; Davis RL; Dublin S; Hammad TA; Kaplan S; Pawloski PA; Raebel MA; Scott PE; Smith DH; Toh S; Li DK

Matern Child Health J. 2014 Jan;18(1):64-72.

PubMed abstract

Effectiveness of seasonal trivalent influenza vaccine for preventing influenza virus illness among pregnant women: a population-based case-control study during the 2010-2011 and 2011-2012 influenza seasons

Author(s): Thompson MG; Li DK; Shifflett P; Sokolow LZ; Ferber JR; Kurosky S; Bozeman S; Reynolds SB; Odouli R; Henninger ML; Kauffman TL; Avalos LA; Ball S; Williams JL; Irving SA; Shay DK; Naleway AL; Pregnancy and Influenza Project Workgroup

Clin Infect Dis. 2014 Feb;58(4):449-57. Epub 2013-11-26.

PubMed abstract

Prevalence and trends in the use of antipsychotic medications during pregnancy in the U.S., 2001-2007: a population-based study of 585,615 deliveries

Author(s): Toh S; Li Q; Cheetham TC; Cooper WO; Davis RL; Dublin S; Hammad TA; Li DK; Pawloski PA; Pinheiro SP; Raebel MA; Scott PE; Smith DH; Bobo WV; Lawrence JM; Dashevsky I; Haffenreffer K; Avalos LA; Andrade SE

Arch Womens Ment Health. 2013 Apr;16(2):149-57. Epub 2013 Feb 7.

PubMed abstract

Prevalence, Trends, and Patterns of Use of Antidiabetic Medications Among Pregnant Women, 2001-2007

Author(s): Lawrence JM; Andrade SE; Avalos LA; Beaton SJ; Chiu VY; Davis RL; Dublin S; Pawloski PA; Raebel MA; Smith DH; Toh S; Wang JQ; Kaplan S; Amini T; Hampp C; Hammad TA; Scott PE; Cheetham TC; Medication Exposure in Pregnancy Risk Evaluation Program (MEPREP) Study Group

Obstet Gynecol. 2013 Jan;121(1):106-14.

PubMed abstract

Trends in the Use of Antiepileptic Drugs among Pregnant Women in the US, 2001-2007: A Medication Exposure in Pregnancy Risk Evaluation Program Study

Author(s): Bobo WV; Davis RL; Toh S; Li DK; Andrade SE; Cheetham TC; Pawloski P; Dublin S; Pinheiro S; Hammad T; Scott PE; Epstein RA Jr; Arbogast PG; Morrow JA; Dudley JA; Lawrence JM; Avalos LA; Cooper WO

Paediatr Perinat Epidemiol. 2012 Nov;26(6):578-88.

PubMed abstract

Alcohol, tobacco and drug use as reasons for abortion

Author(s): Roberts SC; Avalos LA; Sinkford D; Foster DG

Alcohol Alcohol. 2012 Nov-Dec;47(6):640-8. Epub 2012 Aug 22.

PubMed abstract

A systematic review to calculate background miscarriage rates using life table analysis

Author(s): Ammon Avalos L; Galindo C; Li DK

Birth Defects Res A Clin Mol Teratol. 2012 Jun;94(6):417-23. Epub 2012 Apr 18.

PubMed abstract

Does Lack of Multinutrient Supplementation During Early Pregnancy Increase Vulnerability to Alcohol-Related Preterm or Small-for-Gestational-Age Births?

Author(s): Avalos LA; Kaskutas L; Block G; Abrams B; Li DK

Matern Child Health J. 2011 Nov;15(8):1324-32.

PubMed abstract

Stress, substance use and sexual risk behaviors among primary care patients in Cape Town, South Africa

Author(s): Avalos LA; Mertens JR; Ward CL; Flisher AJ; Bresick GF; Weisner CM

AIDS Behav. 2010 Apr;14(2):359-70. Epub 2009 Feb 10.

PubMed abstract

Do multivitamin supplements modify the relationship between prenatal alcohol intake and miscarriage?

Author(s): Ammon Avalos L; Kaskutas LA; Block G; Li DK

Am J Obstet Gynecol. 2009 Dec;201(6):563.e1-9. Epub 2009 Oct 20.

PubMed abstract