Cynthia I. Campbell, PhD, MPH

People

Kaiser Permanente Division of Research
2000 Broadway
Oakland, CA 94612

(510) 891-3584 (phone)
cynthia.i.campbell@kp.org
Kaiser Permanente Researcher Profiles

Dr. Cynthia Campbell is a research scientist at the Division of Research, Kaiser Permanente Northern California, conducting research on the treatment of substance use and mental health problems. She is also an Adjunct Associate Professor in the Department of Psychiatry, University of California, San Francisco. Her interests include access to treatment, chronic pain and substance use, prescription opioid use and misuse, adolescent behavioral health, benefit design and cost sharing, and organizational factors and policy related to these areas. She is currently the principal investigator of a NIDA-funded study examining the impact of the ACA on addiction and HIV services, a NIDA-funded study examining substance use service intensity for buprenorphine patients, and a PCORI-funded study of a patient activation intervention in primary care for chronic pain patients starting long-term prescription opioid use. Her work also includes the assessment of attention deficit hyperactivity disorder (ADHD) in children. She received her doctorate in Public Health at the University of Michigan, and conducted her postdoctoral work at UCSF in a NIDA-funded fellowship on Substance Abuse and Health Services.

Current Position(s):

Research Scientist III, Division of Research, Kaiser Permanente Northern California
Adjunct Associate Professor, University of California, San Francisco, Department of Psychiatry
Co-director, Center for Addiction and Mental Health Research

Section Affiliations:

Primary Research Interests:

Alcohol and drug treatment
Chronic pain and prescription opioid misuse
Adolescents
Mental health
Health services
Benefit design
Access to treatment

Related Website(s):

Studies

Role of Health Care in Addressing Unhealthy Alcohol Use and Disparities among Aging Women

The use of alcohol among older women, particularly binge drinking, has been steadily increasing in recent years, leaving them vulnerable to associated health conditions. This mixed methods study uses KPNC's EHR based alcohol registry and screening data to examine unhealthy alcohol use, and disparities in use, in women over age 50. We will also examine patterns of health care utilization associated with select health conditions among older women with unhealthy alcohol use and conduct qualitative interviews with addiction medicine staff about the changing needs of older women with unhealthy alcohol use.
Investigator: Campbell, Cynthia
Funder: National Institute on Alcohol Abuse and Alcoholism

Buprenorphine Effect on Suicidal Behavior

Large observational study to evaluate the effects of initiating buprenorphine treatment on subsequent suicidal behavior among people with opioid use disorder.
Investigator: Campbell, Cynthia
Funder: National Institute of Mental Health

Alcohol-Related Care and HCV Treatment among Patients with Problematic Alcohol Use and HCV

This study will examine substance use treatment among patients with hepatitis C who have unhealthy alcohol use and how well they engage in appropriate and timely hepatitis C care. The findings will be used to conduct an intervention study aimed at improving engagement with substance use treatment and hepatitis C care in this population.
Investigator: Campbell, Cynthia
Funder: Northern California Community Benefit Programs

A Prospective, Observational Study Designed to Quantify the Serious Risks of Misuse, Abuse and Addiction Associated with Long-Term Use of Opioid Analgesics for Management of Chronic Pain Among Patients Prescribed ER/LA Opioid Analgesics

The goal of this Food and Drug Administration-mandated study is to provide quantitative estimates of the serious risks of misuse, abuse, addiction, overdose, and death associated with long-term use of opioid analgesics for management of chronic pain, among patients prescribed extended-release and long-acting (ER/LA) opioid products. Patients will be recruited and interviewed across several health system sites.
Investigator: Campbell, Cynthia
Funder: Syneos Health

Developing a Prescription Opioid Registry in Diverse Health Systems

Building on past research, this project will establish the infrastructure to expand a prescription opioid registry across diverse health systems in the Addiction Research Network. Harmonized electronic health record data elements will be used to examine how changes in opioid use are associated with other patient outcomes, such as emergency department service utilization, benzodiazepine use, and use of other non-opioid medications (e.g., nonsteroidal anti-inflammatory drugs [NSAIDs] and gabapentin), and how this may vary by patient characteristics and across health systems.
Investigator: Campbell, Cynthia
Funder: National Institute on Drug Abuse

Impact of the Regional Opioid Safety Initiative on Patients and the Health System

Investigator: Campbell, Cynthia
Funder: The Permanente Medical Group

Recreational and Medical Use of Cannabis in a Time of Legalization and Changing Attitudes

This study will survey a sample of patients with pain about their use of medical marijuana. The goal is to describe patterns of use, mode, medical conditions, or symptoms for which medical marijuana is used, as well as perceived benefits, side effects, and patient experience of communication about its use with providers.
Investigator: Campbell, Cynthia
Funder: Northern California Community Benefit Programs

Integrating Addiction Research in Health Systems: The Addiction Research Network

This cooperative agreement supports addiction research in 15 health systems from across the U.S. by establishing the Health Systems Network (HSN) node of the NIDA Clinical Trials Network. HSN research includes a range of study designs and settings, but emphasizes integrating addiction treatment into medical settings and health systems.
Investigator: Campbell, Cynthia
Funder: National Institute on Drug Abuse

Prescription Opioid Management in Chronic Pain Patients: A Patient-Centered Activation Intervention

This randomized trial is based in primary care and focuses on management of prescription opioids among chronic pain patients. The intervention uses a patient activation approach to self-management for these patients and to link them to existing health plan resources.
Investigator: Campbell, Cynthia
Funder: Patient-Centered Outcomes Research Institute

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

This study is a randomized trial of adjunctive substance abuse services in combination with buprenorphine treatment for opioid abuse/dependence. We will examine treatment as usual vs. case management/telephonic support, and outcomes of medication compliance, substance use and psychiatric severity.
Investigator: Campbell, Cynthia
Funder: National Institute on Drug Abuse

The Impact of Health Care Reform on Addiction and HIV Services

To examine the impact of the ACA on treatment for individuals with drug use disorders and who are HIV+. We will examine how this population changes after 2014 enrollment, and subsequent substance abuse treatment and HIV treatment utilization. We will examine findings for different coverage groups, and explore organizational response to changes in this population. The study uses EMR data supplemented by qualitative interviews with patients and providers.
Investigator: Campbell, Cynthia
Funder: National Institute on Drug Abuse

Highlighted Publications

Marijuana use and service utilization among adolescents 7 years post substance use treatment

Author(s): Campbell CI; Sterling S; Chi FW; Kline-Simon AH

Drug Alcohol Depend. 2016 Nov 01;168:1-7. Epub 2016-08-23.

Current Position(s):

Section Affiliations:

Primary Research Interests:

Related Website(s):

Studies

Role of Health Care in Addressing Unhealthy Alcohol Use and Disparities among Aging Women

Buprenorphine Effect on Suicidal Behavior

Alcohol-Related Care and HCV Treatment among Patients with Problematic Alcohol Use and HCV

A Prospective, Observational Study Designed to Quantify the Serious Risks of Misuse, Abuse and Addiction Associated with Long-Term Use of Opioid Analgesics for Management of Chronic Pain Among Patients Prescribed ER/LA Opioid Analgesics

Developing a Prescription Opioid Registry in Diverse Health Systems

Impact of the Regional Opioid Safety Initiative on Patients and the Health System

Recreational and Medical Use of Cannabis in a Time of Legalization and Changing Attitudes

Integrating Addiction Research in Health Systems: The Addiction Research Network

Prescription Opioid Management in Chronic Pain Patients: A Patient-Centered Activation Intervention

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

The Impact of Health Care Reform on Addiction and HIV Services

Highlighted Publications

Marijuana use and service utilization among adolescents 7 years post substance use treatment

High-Deductible Health Plans: Implications for Substance Use Treatment

Age and gender trends in long-term opioid analgesic use for noncancer pain

Publications

The association between buprenorphine treatment duration and mortality: a multi-site cohort study of people who discontinued treatment

Telemedicine along the cascade of care for substance use disorders during the COVID-19 pandemic in the United States

Baseline representativeness of patients in clinics enrolled in the PRimary care Opioid Use Disorders treatment (PROUD) trial: comparison of trial and non-trial clinics in the same health systems

Sex Differences in Comorbid Mental and Substance Use Disorders Among Primary Care Patients With Opioid Use Disorder

COVID-19 pandemic-related changes in utilization of telehealth and treatment overall for alcohol use problems

Patterns of Health Care Use 5 Years After an Intervention Linking Patients in Addiction Treatment With a Primary Care Practitioner

Geographic Accessibility of Retail Cannabis in Northern California and Prenatal Cannabis Use During the COVID-19 Pandemic

Development and Testing of a Communication Intervention to Improve Chronic Pain Management in Primary Care: A Pilot Randomized Clinical Trial

Accuracy of diagnostic codes for prenatal opioid exposure and neonatal opioid withdrawal syndrome

The Opioid Use Disorder Core Outcomes Set (OUD-COS) for treatment research: findings from a Delphi consensus study

Mortality Among Patients Prescribed Buprenorphine for Opioid Use Disorder After Disenrollment from an Insurance Plan and Healthcare System

Development and implementation of a prescription opioid registry across diverse health systems

Alcohol brief intervention, specialty treatment and drinking outcomes at 12 months: Results from a systematic alcohol screening and brief intervention initiative in adult primary care

Comparison of Medical Cannabis Use Reported on a Confidential Survey vs Documented in the Electronic Health Record Among Primary Care Patients

Cigarette Smoking and Risk of SARS-CoV-2 infection and Disease Severity Among Adults in an Integrated Health Care System in California

Substance use disorders among primary care patients screening positive for unhealthy alcohol use

Clinical documentation of patient-reported medical cannabis use in primary care: Toward scalable extraction using natural language processing methods

The Feasibility and Utility of Harnessing Digital Health to Understand Clinical Trajectories in Medication Treatment for Opioid Use Disorder: D-TECT Study Design and Methodological Considerations

Alcohol Use Among Young Adults in Northern California During the COVID-19 Pandemic-An Electronic Health Records-Based Study

Attention-Deficit/Hyperactivity Disorder Medication Adherence in the Transition to Adulthood: Associated Adverse Outcomes for Females and Other Disparities

Patient and provider factors associated with receipt and delivery of brief interventions for unhealthy alcohol use in primary care

Receipt of medications for opioid use disorder among youth engaged in primary care: data from 6 health systems

Prevalence of Medical Cannabis Use and Associated Health Conditions Documented in Electronic Health Records Among Primary Care Patients in Washington State

Prevalence and Medication Treatment of Opioid Use Disorder Among Primary Care Patients with Hepatitis C and HIV

Changes in Diagnostic and Demographic Characteristics of Patients Seeking Mental Health Care During the Early COVID-19 Pandemic in a Large, Community-Based Health Care System

PRimary Care Opioid Use Disorders treatment (PROUD) trial protocol: a pragmatic, cluster-randomized implementation trial in primary care for opioid use disorder treatment

Core outcomes set for research on the treatment of opioid use disorder (COS-OUD): the National Institute on Drug Abuse Clinical Trials Network protocol for an e-Delphi consensus study

Treatment for Anxiety and Substance Use Disorders During the COVID-19 Pandemic: Challenges and Strategies

Health care utilization and HIV clinical outcomes among newly enrolled patients following Affordable Care Act implementation in a California integrated health system: a longitudinal study

Healthcare utilization of individuals with substance use disorders following Affordable Care Act implementation in a California healthcare system

The role of substance use disorders in experiencing a repeat opioid overdose, and substance use treatment patterns among patients with a non-fatal opioid overdose

The application of digital health to the assessment and treatment of substance use disorders: The past, current, and future role of the National Drug Abuse Treatment Clinical Trials Network

Documented opioid use disorder and its treatment in primary care patients across six U.S. health systems

Prevalence and treatment of opioid use disorders among primary care patients in six health systems

Chronic pain diagnoses and opioid dispensings among insured individuals with serious mental illness

Long-term opioid therapy definitions and predictors: A systematic review

Postoperative Opioid Use Before and After Enhanced Recovery After Surgery Program Implementation

Benzodiazepine and unhealthy alcohol use among adult outpatients

Enhanced Recovery After Surgery to Change Process Measures and Reduce Opioid Use After Cesarean Delivery: A Quality Improvement Initiative

Disparities in knowledge and use of tobacco treatment among smokers in California following healthcare reform

A Quality Framework for Emergency Department Treatment of Opioid Use Disorder

Trends in marijuana use among pregnant women with and without nausea and vomiting in pregnancy, 2009-2016

Psychiatric comorbidity and Healthcare Effectiveness Data and Information Set (HEDIS) measures of alcohol and other drug treatment initiation and engagement across 7 health care systems

Predictors of Healthcare Effectiveness Data and Information Set (HEDIS) treatment initiation and engagement among patients with opioid use disorder across 7 health systems

Factors associated with Healthcare Effectiveness Data and Information Set (HEDIS) alcohol and other drug measure performance in 2014-2015

The prevalence of Healthcare Effectiveness Data and Information Set (HEDIS) initiation and engagement in treatment among patients with cannabis use disorders in 7 US health systems

The association between medical comorbidity and Healthcare Effectiveness Data and Information Set (HEDIS) measures of treatment initiation and engagement for alcohol and other drug use disorders

Patient characteristics associated with treatment initiation and engagement among individuals diagnosed with alcohol and other drug use disorders in emergency department and primary care settings

Healthcare Effectiveness Data and Information Set (HEDIS) measures of alcohol and drug treatment initiation and engagement among people living with the human immunodeficiency virus (HIV) and patients without an HIV diagnosis

Medical and non-medical marijuana use in depression: Longitudinal associations with suicidal ideation, everyday functioning, and psychiatry service utilization

Characteristics of patients with substance use disorder before and after the Affordable Care Act

Evaluating the Impact of Eliminating Copayments for Tobacco Cessation Pharmacotherapy

Patient and System Characteristics Associated with Performance on the HEDIS Measures of Alcohol and Other Drug Treatment Initiation and Engagement

Use of a prescription opioid registry to examine opioid misuse and overdose in an integrated health system

Alcohol, Marijuana, and Opioid Use Disorders: 5-Year Patterns and Characteristics of Emergency Department Encounters

Adverse impact of marijuana use on clinical outcomes among psychiatry patients with depression and alcohol use disorder

Alcohol and Drug Use, Pain and Psychiatric Symptoms among Adults Seeking Outpatient Psychiatric Treatment: Latent Class Patterns and Relationship to Health Status

The role of marijuana use disorder in predicting emergency department and inpatient encounters: A retrospective cohort study

Serious mental illness and medical comorbidities: Findings from an integrated health care system