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Cynthia I. Campbell, PhD, MPH

People

Kaiser Permanente Division of Research
2000 Broadway
Oakland, CA 94612

(510) 891-3584 (phone)
cynthia.i.campbell@kp.org
Kaiser Permanente Researcher Profiles


Dr. Cynthia Campbell is a research scientist at the Division of Research, Kaiser Permanente Northern California, conducting research on the treatment of substance use and mental health problems. She is also an Adjunct Associate Professor in the Department of Psychiatry, University of California, San Francisco. Her interests include access to treatment, chronic pain and substance use, prescription opioid use and misuse, adolescent behavioral health, benefit design and cost sharing, and organizational factors and policy related to these areas. She is currently the principal investigator of a NIDA-funded study examining the impact of the ACA on addiction and HIV services, a NIDA-funded study examining substance use service intensity for buprenorphine patients, and a PCORI-funded study of a patient activation intervention in primary care for chronic pain patients starting long-term prescription opioid use. Her work also includes the assessment of attention deficit hyperactivity disorder (ADHD) in children. She received her doctorate in Public Health at the University of Michigan, and conducted her postdoctoral work at UCSF in a NIDA-funded fellowship on Substance Abuse and Health Services.

Current Position(s):

  • Research Scientist III, Division of Research, Kaiser Permanente Northern California
  • Adjunct Associate Professor, University of California, San Francisco, Department of Psychiatry

Section Affiliations:

Primary Research Interests:

  • Alcohol and drug treatment
  • Chronic pain and prescription opioid misuse
  • Adolescents
  • Mental health
  • Health services
  • Benefit design
  • Access to treatment

Related Website(s):

A Prospective, Observational Study Designed to Quantify the Serious Risks of Misuse, Abuse and Addiction Associated with Long-Term Use of Opioid Analgesics for Management of Chronic Pain Among Patients Prescribed ER/LA Opioid Analgesics

​The goal of this Food and Drug Administration-mandated study is to provide quantitative estimates of the serious risks of misuse, abuse, addiction, overdose, and death associated with long-term use of opioid analgesics for management of chronic pain, among patients prescribed extended-release and long-acting (ER/LA) opioid products. Patients will be recruited and interviewed across several health system sites.


Investigator: Campbell, Cynthia
Funder: 

Developing a Prescription Opioid Registry in Diverse Health Systems

​Building on past research, this project will establish the infrastructure to expand a prescription opioid registry across diverse health systems in the Addiction Research Network. Harmonized electronic health record data elements will be used to examine how changes in opioid use are associated with other patient outcomes, such as emergency department service utilization, benzodiazepine use, and use of other non-opioid medications (e.g., nonsteroidal anti-inflammatory drugs [NSAIDs] and gabapentin), and how this may vary by patient characteristics and across health systems.


Investigator: Campbell, Cynthia
Funder: National Institute on Drug Abuse

Impact of the Regional Opioid Safety Initiative on Patients and the Health System

Investigator: Campbell, Cynthia
Funder: The Permanente Medical Group

Recreational and Medical Use of Cannabis in a Time of Legalization and Changing Attitudes

This study will survey a sample of patients with pain about their use of medical marijuana. The goal is to describe patterns of use, mode, medical conditions, or symptoms for which medical marijuana is used, as well as perceived benefits, side effects, and patient experience of communication about its use with providers.
Investigator: Campbell, Cynthia
Funder: Northern California Community Benefit Programs

Integrating Addiction Research in Health Systems: The Addiction Research Network

This cooperative agreement supports addiction research in 15 health systems from across the U.S. by establishing the Health Systems Network (HSN) node of the NIDA Clinical Trials Network. HSN research includes a range of study designs and settings, but emphasizes integrating addiction treatment into medical settings and health systems.
Investigator: Campbell, Cynthia
Funder: National Institute on Drug Abuse

Prescription Opioid Management in Chronic Pain Patients: A Patient-Centered Activation Intervention

This randomized trial is based in primary care and focuses on management of prescription opioids among chronic pain patients. The intervention uses a patient activation approach to self-management for these patients and to link them to existing health plan resources.
Investigator: Campbell, Cynthia
Funder: Patient-Centered Outcomes Research Institute

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

This study is a randomized trial of adjunctive substance abuse services in combination with buprenorphine treatment for opioid abuse/dependence. We will examine treatment as usual vs. case management/telephonic support, and outcomes of medication compliance, substance use and psychiatric severity.
Investigator: Campbell, Cynthia
Funder: National Institute on Drug Abuse

The Impact of Health Care Reform on Addiction and HIV Services

To examine the impact of the ACA on treatment for individuals with drug use disorders and who are HIV+. We will examine how this population changes after 2014 enrollment, and subsequent substance abuse treatment and HIV treatment utilization. We will examine findings for different coverage groups, and explore organizational response to changes in this population. The study uses EMR data supplemented by qualitative interviews with patients and providers.
Investigator: Campbell, Cynthia
Funder: National Institute on Drug Abuse

Marijuana use and service utilization among adolescents 7 years post substance use treatment

Author(s): Campbell CI; Sterling S; Chi FW; Kline-Simon AH

Drug Alcohol Depend. 2016 Aug 23;168:1-7. Epub 2016-8-23.

PubMed abstract

High-Deductible Health Plans: Implications for Substance Use Treatment

Author(s): Parthasarathy S; Campbell CI

Health Serv Res. 2016 Feb 3.

PubMed abstract

Age and gender trends in long-term opioid analgesic use for noncancer pain

Author(s): Campbell CI; Weisner C; Leresche L; Ray GT; Saunders K; Sullivan MD; Banta-Green CJ; Merrill JO; Silverberg MJ; Boudreau D; Satre DD; Von Korff M

Am J Public Health. 2010 Dec;100(12):2541-7. Epub 2010 Aug 19.

PubMed abstract

A Quality Framework for Emergency Department Treatment of Opioid Use Disorder

Author(s): Samuels EA; D'Onofrio G; Huntley K; Levin S; Schuur JD; Bart G; Hawk K; Tai B; Campbell CI; Venkatesh AK

Ann Emerg Med. 2018 Oct 11.

PubMed abstract

Characteristics of patients with substance use disorder before and after the Affordable Care Act

Author(s): Campbell CI; Parthasarathy S; Altschuler A; Young-Wolff KC; Satre DD

Drug Alcohol Depend. 2018 Oct 06;193:124-130. Epub 2018-10-06.

PubMed abstract

Evaluating the Impact of Eliminating Copayments for Tobacco Cessation Pharmacotherapy

Author(s): Young-Wolff KC; Adams SR; Klebaner D; Adams AS; Campbell CI; Satre DD; Prochaska JJ

Med Care. 2018 Sep 18.

PubMed abstract

Medical and non-medical marijuana use in depression: Longitudinal associations with suicidal ideation, everyday functioning, and psychiatry service utilization

Author(s): Bahorik AL; Sterling SA; Campbell CI; Weisner C; Ramo D; Satre DD

J Affect Disord. 2018 Dec 01;241:8-14. Epub 2018-07-17.

PubMed abstract

Patient and System Characteristics Associated with Performance on the HEDIS Measures of Alcohol and Other Drug Treatment Initiation and Engagement

Author(s): Yarborough BJH; Chi FW; Green CA; Hinman A; Mertens J; Beck A; Horberg M; Weisner C; Campbell CI

J Addict Med. 2018 Mar 19.

PubMed abstract

Use of a prescription opioid registry to examine opioid misuse and overdose in an integrated health system

Author(s): Campbell CI; Bahorik AL; VanVeldhuisen P; Weisner C; Rubinstein AL; Ray GT

Prev Med. 2018 Feb 02;110:31-37. Epub 2018-02-02.

PubMed abstract

Alcohol and Drug Use, Pain and Psychiatric Symptoms among Adults Seeking Outpatient Psychiatric Treatment: Latent Class Patterns and Relationship to Health Status

Author(s): Ramo DE; Bahorik AL; Delucchi KL; Campbell CI; Satre DD

J Psychoactive Drugs. 2017 Dec 04:1-11.

PubMed abstract

Adverse impact of marijuana use on clinical outcomes among psychiatry patients with depression and alcohol use disorder

Author(s): Bahorik AL; Campbell CI; Sterling SA; Leibowitz A; Travis A; Weisner CM; Satre DD

Psychiatry Res. 2017 Oct 19;259:316-322. Epub 2017-10-19.

PubMed abstract

Alcohol, Marijuana, and Opioid Use Disorders: 5-Year Patterns and Characteristics of Emergency Department Encounters

Author(s): Bahorik AL; Satre DD; Kline-Simon AH; Weisner CM; Young-Wolff KC; Campbell CI

Subst Abus. 2017 Jul 19:0.

PubMed abstract

Serious mental illness and medical comorbidities: Findings from an integrated health care system

Author(s): Bahorik AL; Satre DD; Kline-Simon AH; Weisner CM; Campbell CI

J Psychosom Res. 2017 Sep;100:35-45. Epub 2017-07-08.

PubMed abstract

The role of marijuana use disorder in predicting emergency department and inpatient encounters: A retrospective cohort study

Author(s): Campbell CI; Bahorik AL; Kline-Simon AH; Satre DD

Drug Alcohol Depend. 2017 Jun 10;178:170-175. Epub 2017-06-10.

PubMed abstract

Socioeconomic differences in adolescent substance abuse treatment participation and long-term outcomes

Author(s): Lui CK; Sterling SA; Chi FW; Lu Y; Campbell CI

Addict Behav. 2017 May;68:45-51. Epub 2017-01-06.

PubMed abstract

The high price of depression: Family members' health conditions and health care costs

Author(s): Ray GT; Weisner CM; Taillac CJ; Campbell CI

Gen Hosp Psychiatry. 2017 May;46:79-87. Epub 2017-04-08.

PubMed abstract

Prescription opioid registry protocol in an integrated health system

Author(s): Ray GT; Bahorik AL; VanVeldhuisen PC; Weisner CM; Rubinstein AL; Campbell CI

Am J Manag Care. 2017 May 01;23(5):e146-e155. Epub 2017-05-01.

PubMed abstract

Buprenorphine Treatment and Patient Use of Health Services after the Affordable Care Act in an Integrated Health Care System

Author(s): Campbell CI; Parthasarathy S; Young-Wolff KC; Satre DD

J Psychoactive Drugs. 2017 Apr 20:1-9.

PubMed abstract

Alcohol and Drug Use and Aberrant Drug-Related Behavior Among Patients on Chronic Opioid Therapy

Author(s): Campbell CI; Kline-Simon AH; Von Korff M; Saunders KW; Weisner C

Subst Use Misuse. 2017 Mar 27:1-9.

PubMed abstract

Association of the Affordable Care Act With Smoking and Tobacco Treatment Utilization Among Adults Newly Enrolled in Health Care

Author(s): Young-Wolff KC; Klebaner D; Campbell CI; Weisner C; Satre DD; Adams AS

Med Care. 2017 Mar 10.

PubMed abstract

Smoking Status and Opioid Related Problems and Concerns among Men and Women on Chronic Opioid Therapy

Author(s): Young-Wolff KC; Klebaner D; Weisner C; Von Korff M; Campbell CI

Clin J Pain. 2016 Nov 28.

PubMed abstract

Affordable Care Act Implementation in a California Health Care System Leads to Growth in HIV-Positive Patient Enrollment and Changes in Patient Characteristics

Author(s): Satre DD; Altschuler A; Parthasarathy S; Silverberg MJ; Volberding P; Campbell CI

J Acquir Immune Defic Syndr. 2016 Oct 03.

PubMed abstract

Alcohol, Cannabis, and Opioid Use Disorders, and Disease Burden in an Integrated Health Care System

Author(s): Bahorik AL; Satre DD; Kline-Simon AH; Weisner CM; Campbell CI

J Addict Med. 2016 Sep 8.

PubMed abstract

Marijuana use and service utilization among adolescents 7 years post substance use treatment

Author(s): Campbell CI; Sterling S; Chi FW; Kline-Simon AH

Drug Alcohol Depend. 2016 Aug 23;168:1-7. Epub 2016-8-23.

PubMed abstract

High-Deductible Health Plans: Implications for Substance Use Treatment

Author(s): Parthasarathy S; Campbell CI

Health Serv Res. 2016 Feb 3.

PubMed abstract

Physician versus non-physician delivery of alcohol screening, brief intervention and referral to treatment in adult primary care: the ADVISe cluster randomized controlled implementation trial

Author(s): Mertens JR; Chi FW; Weisner CM; Satre DD; Ross TB; Allen S; Pating D; Campbell CI; Lu YW; Sterling SA

Addict Sci Clin Pract. 2015;10(1):26. Epub 2015-11-19.

PubMed abstract

Sex and Age Differences in Global Pain Status Among Patients Using Opioids Long Term for Chronic Noncancer Pain

Author(s): LeResche L; Saunders K; Dublin S; Thielke S; Merrill JO; Shortreed SM; Campbell C; Von Korff MR

J Womens Health (Larchmt). 2015 Jul 8.

PubMed abstract

Do Patient-perceived Pros and Cons of Opioids Predict Sustained Higher-Dose Use?

Author(s): Thielke SM; Turner JA; Shortreed SM; Saunders K; Leresche L; Campbell CI; Weisner CC; Korff MV

Clin J Pain. 2014 Feb;30(2):93-101.

PubMed abstract

12-step participation and outcomes over 7 years among adolescent substance use patients with and without psychiatric comorbidity

Author(s): Chi FW; Sterling S; Campbell CI; Weisner C

Subst Abus. 2013;34(1):33-42.

PubMed abstract

Prescribed opioid difficulties, depression and opioid dose among chronic opioid therapy patients

Author(s): Merrill JO; Von Korff M; Banta-Green CJ; Sullivan MD; Saunders KW; Campbell CI; Weisner C

Gen Hosp Psychiatry. 2012 Nov-Dec;34(6):581-7. Epub 2012 Sep 5.

PubMed abstract

Depression and Ambivalence Toward Chronic Opioid Therapy for Chronic Noncancer Pain

Author(s): Howe CQ; Sullivan MD; Saunders KW; Merrill JO; Banta-Green CJ; Weisner C; Campbell CI; Von Korff M

Clin J Pain. 2012 Sep;28(7):561-6.

PubMed abstract

Depression and prescription opioid misuse among chronic opioid therapy recipients with no history of substance abuse

Author(s): Grattan A; Sullivan MD; Saunders KW; Campbell CI; Von Korff MR

Ann Fam Med. 2012 Jul-Aug;10(4):304-11.

PubMed abstract

12-Step participation reduces medical use costs among adolescents with a history of alcohol and other drug treatment

Author(s): Mundt MP; Parthasarathy S; Chi FW; Sterling S; Campbell CI

Drug Alcohol Depend. 2012 Nov 1;126(1-2):124-30. Epub 2012 May 26.

PubMed abstract

Peer Influences on Adolescent Alcohol and Other Drug Use Outcomes

Author(s): Ramirez R; Hinman A; Sterling S; Weisner C; Campbell C

J Nurs Scholarsh. 2012 Mar;44(1):36-44. Epub 2012 Feb 16.

PubMed abstract

Twelve-step attendance trajectories over seven years among adolescents entering substance use treatment in an integrated health plan

Author(s): Chi FW; Campbell CI; Sterling S; Weisner C

Addiction. 2012 May;107(5):933-42. Epub 2012 Feb 11.

PubMed abstract

Concurrent Use of Alcohol and Sedatives Among Persons Prescribed Chronic Opioid Therapy: Prevalence and Risk Factors

Author(s): Saunders KW; Von Korff M; Campbell CI; Banta-Green CJ; Sullivan MD; Merrill JO; Weisner C

J Pain. 2012 Mar;13(3):266-75. Epub 2012 Jan 29.

PubMed abstract

Prescription Long-term Opioid Use in HIV-infected Patients

Author(s): Silverberg MJ; Ray GT; Saunders K; Rutter CM; Campbell CI; Merrill JO; Sullivan MD; Von Korff M; Weisner C; Banta-Green CJ

Clin J Pain. 2012 Jan;28(1):39-46.

PubMed abstract

Time-scheduled vs. pain-contingent opioid dosing in chronic opioid therapy

Author(s): Von Korff M; Merrill JO; Rutter CM; Sullivan M; Campbell CI; Weisner C

Pain. 2011 Jun;152(6):1256-62. Epub 2011 Feb 5.

PubMed abstract

Age and gender trends in long-term opioid analgesic use for noncancer pain

Author(s): Campbell CI; Weisner C; Leresche L; Ray GT; Saunders K; Sullivan MD; Banta-Green CJ; Merrill JO; Silverberg MJ; Boudreau D; Satre DD; Von Korff M

Am J Public Health. 2010 Dec;100(12):2541-7. Epub 2010 Aug 19.

PubMed abstract

Opioid prescriptions for chronic pain and overdose: a cohort study

Author(s): Dunn KM; Saunders KW; Rutter CM; Banta-Green CJ; Merrill JO; Sullivan MD; Weisner CM; Silverberg MJ; Campbell CI; Psaty BM; Von Korff M

Ann Intern Med. 2010 Jan 19;152(2):85-92.

PubMed abstract

Ethnic disparities in accessing treatment for depression and substance use disorders in an integrated health plan

Author(s): Satre DD; Campbell CI; Gordon NS; Weisner C

Int J Psychiatry Med. 2010;40(1):57-76.

PubMed abstract

Trends in long-term opioid therapy for chronic non-cancer pain

Author(s): Boudreau D; Von Korff M; Rutter CM; Saunders K; Ray GT; Sullivan MD; Campbell CI; Merrill JO; Silverberg MJ; Banta-Green C; Weisner C

Pharmacoepidemiol Drug Saf. 2009 Dec;18(12):1166-75.

PubMed abstract

Trends in long-term opioid therapy for noncancer pain among persons with a history of depression

Author(s): Braden JB; Sullivan MD; Ray GT; Saunders K; Merrill J; Silverberg MJ; Rutter CM; Weisner C; Banta-Green C; Campbell C; Von Korff M

Gen Hosp Psychiatry. 2009 Nov-Dec;31(6):564-70. Epub 2009 Aug 27.

PubMed abstract

Three-year chemical dependency and mental health treatment outcomes among adolescents: the role of continuing care

Author(s): Sterling S; Chi F; Campbell C; Weisner C

Alcohol Clin Exp Res. 2009 Aug;33(8):1417-29. Epub 2009 Apr 30.

PubMed abstract

Trends in prescribed opioid therapy for non-cancer pain for individuals with prior substance use disorders

Author(s): Weisner CM; Campbell CI; Ray GT; Saunders K; Merrill JO; Banta-Green C; Sullivan MD; Silverberg MJ; Mertens JR; Boudreau D; Von Korff M

Pain. 2009 Oct;145(3):287-93. Epub 2009 Jul 5.

PubMed abstract

Twelve-Step affiliation and 3-year substance use outcomes among adolescents: social support and religious service attendance as potential mediators

Author(s): Chi FW; Kaskutas LA; Sterling S; Campbell CI; Weisner C

Addiction. 2009 Jun;104(6):927-39. Epub 2009 Mar 13.

PubMed abstract

Organizational determinants of outpatient substance abuse treatment duration in women

Author(s): Campbell CI; Alexander JA; Lemak CH

J Subst Abuse Treat. 2009 Jul;37(1):64-72. Epub 2008 Nov 26.

PubMed abstract

Self-initiated tobacco cessation and substance use outcomes among adolescents entering substance use treatment in a managed care organization

Author(s): Campbell CI; Chi F; Sterling S; Kohn C; Weisner C

Addict Behav. 2009 Feb;34(2):171-9. Epub 2008 Oct 10.

PubMed abstract

De facto long-term opioid therapy for noncancer pain

Author(s): Korff MV; Saunders K; Thomas Ray G; Boudreau D; Campbell C; Merrill J; Sullivan MD; Rutter CM; Silverberg MJ; Banta-Green C; Weisner C

Clin J Pain. 2008 Jul-Aug;24(6):521-7.

PubMed abstract

Tailoring of outpatient substance abuse treatment to women, 1995-2005

Author(s): Campbell CI; Wells R; Alexander JA; Jiang L; Nahra TA; Lemak CH

Med Care. 2007 Aug;45(8):775-80.

PubMed abstract

Tailored treatment in the outpatient substance abuse treatment sector: 1995-2005

Author(s): Alexander JA; Nahra TA; Lemak CH; Pollack H; Campbell CI

J Subst Abuse Treat. 2008 Apr;34(3):282-92. Epub 2007 Jun 28.

PubMed abstract

Do licensing and accreditation matter in outpatient substance abuse treatment programs?

Author(s): Wells R; Lemak CH; Alexander JA; Nahra TA; Ye Y; Campbell CI

J Subst Abuse Treat. 2007 Jul;33(1):43-50. Epub 2007 Jan 16.

PubMed abstract

Adolescents entering chemical dependency treatment in private managed care: ethnic differences in treatment initiation and retention

Author(s): Campbell CI; Weisner C; Sterling S

J Adolesc Health. 2006 Apr;38(4):343-50.

PubMed abstract

Availability of services for women in outpatient substance abuse treatment: 1995-2000

Author(s): Campbell CI; Alexander JA

J Behav Health Serv Res. 2006 Jan;33(1):1-19.

PubMed abstract

Health services for women in outpatient substance abuse treatment

Author(s): Campbell CI; Alexander JA

Health Serv Res. 2005 Jun;40(3):781-810.

PubMed abstract