Skip to content

Robert W. Chang, MD

robert.w.chang@kp.org

Kaiser Permanente Researcher Profiles

Robert  Chang, MD

​Robert W. Chang, MD, the Assistant Chair of Vascular Surgery for The Permanente Medical Group, is an Adjunct Investigator with the Division of Research and a physician researcher with the Delivery Science & Applied Research Physician Researcher Program. Dr. Chang is active in the education of residents and fellows and is also affiliated with the University of California, San Francisco, medical training program.

Dr. Chang conducts clinical research aimed at improving patient care. His current research on abdominal aortic aneurysms illustrates how Kaiser Permanente’s integrated health system and established IT infrastructure can be used to develop databases that researchers can use to help patients and doctors make shared medical decisions based on personalized risk analyses.

Dr. Chang earned his medical degree from the University of Southern California. He completed his surgical residency at Yale New Haven Hospital and vascular fellowship at Dartmouth-Hitchcock Medical Center.

Current Position(s):

Section Affiliations:

Primary Research Interests:

  • Optimal management of abdominal aortic aneurysm
  • Outcomes after endovascular aortic aneurysm repair
  • Optimal management of carotid artery disease

Studies

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)

Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multi-center, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1-to-1 ratio to endarterectomy versus no endarterectomy, and another will randomize patients in a 1-to-1 ratio to carotid stenting with embolic protection versus no stenting. Medical management will be uniform for all randomized treatment groups and will be centrally directed. The purpose of this trial is to determine the best way to prevent strokes in people who have a high amount of blockage of their carotid artery but no stroke symptoms related to that blockage.

Investigator: Nguyen-Huynh, Mai; Avins, Andrew; Chang, Robert

Funder: National Institute of Neurological Disorders and Stroke

Publications

Risk for surgical interventions following endovascular aneurysm repair with Endologix AFX or AFX2 Endovascular AAA Systems compared to other devices

Authors: Prentice, Heather A;Paxton, Elizabeth W;Harris, Jessica E;Garg, Joy;Rehring, Thomas F;Nelken, Nicolas A;Hajarizadeh, Homayon;Hsu, Jeffrey H;Chang, Robert W

J Vasc Surg. 2023 Aug;78(2):333-343.e4. Epub 2023-04-08.

PubMed abstract

A comparative effectiveness study of carotid intervention for long-term stroke prevention in patients with severe asymptomatic stenosis from a large integrated health system

Authors: Chang, Robert W;Pimentel, Noel;Tucker, Lue-Yen;Rothenberg, Kara A;Avins, Andrew L;Flint, Alexander C;Faruqi, Rishad M;Nguyen-Huynh, Mai N;Neugebauer, Romain

J Vasc Surg. 2023 Jul 04.

PubMed abstract

Closing the gap in sex-based care disparities in vascular surgery

Authors: Chang, Robert W

J Vasc Surg. 2023 May;77(5):1512.

PubMed abstract

Decreasing Trends in Reintervention and Readmission After Endovascular Aneurysm Repair in a Multiregional Implant Registry

Authors: Le, Sidney T; Prentice, Heather A; Harris, Jessica E; Hsu, Jeffrey H; Rehring, Thomas F; Nelken, Nicolas A; Hajarizadeh, Homayon; Chang, Robert W

J Vasc Surg. 2022 Dec;76(6):1511-1519. Epub 2022-06-14.

PubMed abstract

Association of Thoracic Aortic Aneurysm Size With Long-term Patient Outcomes: The KP-TAA Study

Authors: Solomon, Matthew D; Lee, Catherine; Chang, Robert; Go, Alan S; Kaiser Permanente Northern California Center for Thoracic Aortic Disease ,; et al.

JAMA Cardiol. 2022 Nov 01;7(11):1160-1169.

PubMed abstract

Ischemic Stroke in Patients With Asymptomatic Severe Carotid Stenosis Without Surgical Intervention-Reply

Authors: Chang, Robert W; Nguyen-Huynh, Mai N; Avins, Andrew L

JAMA. 2022 09 27;328(12):1257.

PubMed abstract

Natural History of Asymptomatic Moderate Carotid Artery Stenosis in a Large Community-Based Cohort

Authors: Gologorsky, Rebecca C; Lancaster, Elizabeth; Tucker, Lue-Yen; Nguyen-Huynh, Mai N; Rothenberg, Kara A; Avins, Andrew L; Kuang, Hui C; Chang, Robert W

Stroke. 2022 Sep;53(9):2838-2846. Epub 2022-06-08.

PubMed abstract

Incidence of Ischemic Stroke in Patients With Asymptomatic Severe Carotid Stenosis Without Surgical Intervention

Authors: Chang, Robert W; Tucker, Lue-Yen; Rothenberg, Kara A; Lancaster, Elizabeth; Faruqi, Rishad M; Kuang, Hui C; Flint, Alexander C; Avins, Andrew L; Nguyen-Huynh, Mai N

JAMA. 2022 05 24;327(20):1974-1982.

PubMed abstract

Society for Vascular Surgery clinical practice guidelines for management of extracranial cerebrovascular disease

Authors: AbuRahma, Ali F; Darling, R Clement; Zhou, Wei; et al.

J Vasc Surg. 2022 01;75(1S):4S-22S. Epub 2021-06-19.

PubMed abstract

The Society for Vascular Surgery implementation document for management of extracranial cerebrovascular disease

Authors: AbuRahma, Ali F; Avgerinos, Efthymios D; Chang, Robert W; Darling, R Clement; Duncan, Audra A; Forbes, Thomas L; Malas, Mahmoud B; Perler, Bruce Alan; Powell, Richard J; Rockman, Caron B; Zhou, Wei

J Vasc Surg. 2022 01;75(1S):26S-98S. Epub 2021-06-19.

PubMed abstract

Euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosis

Authors: Gomez-Sanchez, Clara M; Wu, Bian X; Gotts, Jeffrey E; Chang, Robert W

J Vasc Surg Cases Innov Tech. 2021 Dec;7(4):778-780. Epub 2021-10-22.

PubMed abstract

Mid-term outcomes for 605 patients receiving Endologix AFX or AFX2 Endovascular AAA Systems in an integrated healthcare system

Authors: Chang RW; Rothenberg KA; Harris JE; Gologorsky RC; Hsu JH; Rehring TF; Hajarizadeh H; Nelken NA; Paxton EW; Prentice HA

J Vasc Surg. 2021 03;73(3):856-866. Epub 2020-07-03.

PubMed abstract

Long-term freedom from aneurysm-related mortality remains favorable after endovascular abdominal aortic aneurysm repair in a 15-year multicenter registry

Authors: Rich N; Tucker LY; Okuhn S; Hua H; Hill B; Goodney P; Chang R

J Vasc Surg. 2020 03;71(3):790-798. Epub 2019-09-05.

PubMed abstract

Survival and Re-intervention Risk by Patient Age and Preoperative Abdominal Aortic Aneurysm (AAA) Diameter Following Endovascular Aneurysm Repair (EVAR)

Authors: Hye RJ; Janarious AU; Chan PH; Cafri G; Chang RW; Rehring TF; Nelken NA; Hill BB

Ann Vasc Surg. 2019 Jan;54:215-225. Epub 2018-08-04.

PubMed abstract

Type II endoleak with or without intervention after endovascular aortic aneurysm repair does not change aneurysm-related outcomes despite sac growth

Authors: Walker J; Tucker LY; Goodney P; Candell L; Hua H; Okuhn S; Hill B; Chang RW

J Vasc Surg. 2015 Sep;62(3):551-61. Epub 2015-06-06.

PubMed abstract

A multiregional registry experience using an electronic medical record to optimize data capture for longitudinal outcomes in endovascular abdominal aortic aneurysm repair

Authors: Hye RJ; Inui TS; Anthony FF; Kiley ML; Chang RW; Rehring TF; Nelken NA; Hill BB

J Vasc Surg. 2015 May;61(5):1160-6. Epub 2015-02-26.

PubMed abstract

Adherence to endovascular aortic aneurysm repair device instructions for use guidelines has no impact on outcomes

Authors: Walker J; Tucker LY; Goodney P; Candell L; Hua H; Okuhn S; Hill B; Chang RW

J Vasc Surg. 2015 May;61(5):1151-9. Epub 2015-02-03.

PubMed abstract

Early and delayed rupture after endovascular abdominal aortic aneurysm repair in a 10-year multicenter registry

Authors: Candell L; Tucker LY; Goodney P; Walker J; Okuhn S; Hill B; Chang R

J Vasc Surg. 2014 Nov;60(5):1146-52. Epub 2014-06-21.

PubMed abstract

Ten-year results of endovascular abdominal aortic aneurysm repair from a large multicenter registry

Authors: Chang RW; Goodney P; Tucker LY; Okuhn S; Hua H; Rhoades A; Sivamurthy N; Hill B

J Vasc Surg. 2013 Aug;58(2):324-32. Epub 2013 May 14.

PubMed abstract

Back To Top