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Brianna Costales, PhD

brianna.m.costales@kp.org

Costales, Brianna

Brianna Costales, PhD, is a Health Equity and Diversity Scholar and fellow with the Division of Research and its Center for Addiction and Mental Health Research. She received her doctorate in Pharmaceutical Sciences with a specialization in pharmacoepidemiology from the University of Florida, where her dissertation was funded by an R36 Dissertation Grant from the National Institute of Mental Health (NIMH). Dr. Costales completed the NIMH T32 Embedded Mental Health Services Postdoctoral Fellowship at the Division of Research.

Dr. Costales is dedicated to optimizing pharmacotherapy outcomes and advancing healthcare through real-world evidence. Her research encompasses drug utilization, safety, and signal detection across diverse therapeutic areas, including mental health, neurology, diabetes, and substance use. She has a particular interest in the identification of clinically relevant psychiatric adverse events resulting from medication use and long-term safety and efficacy of cannabis. Dr. Costales aims to translate her research into optimal management and safety of medications and substances with the goal of improving patient care and enhancing health outcomes.

Current Positions

  • Postdoctoral Research Fellow

Section Affiliations

Primary Research Interests

  • Mental health
  • Pharmacoepidemiology and pharmacovigilance
  • Central nervous system drugs
  • Long-term effects of cannabis use

Studies

Real-World Evidence for Potential Suicidality Risk with Glucagon-Like Peptide-1 Receptor Agonists

Real-World Evidence for Potential Suicidality Risk with Glucagon-Like Peptide-1 Receptor Agonists
This project will estimate the incidence of new onset suicidality among adults following initiation of a monotherapy glucagon-like peptide-1 receptor agonist (GLP-1RA) medication and to investigate the risk of suicidality with GLP-1RA medications among new users of a monotherapy GLP-1RA drug.
Funder: KPNC Community Health

Investigator: Costales, Brianna

Funder: Northern California Community Benefit Programs

Publications

Prevalence and trends of suspected cannabinoid hyperemesis syndrome over an 11-year period in Northern California: An electronic health record study

Authors: Costales, Brianna;Lu, Yun;Young-Wolff, Kelly C;Cotton, Dale M;Campbell, Cynthia I;Iturralde, Esti;Sterling, Stacy A

Drug Alcohol Depend. 2024 Oct 01;263:112418. Epub 2024-08-17.

PubMed abstract

On- and Off-Label Atypical Antipsychotic Prescription Trends Across a Nine-Year Period Among Adolescents Pre- to Post-COVID-19

Authors: Costales, Brianna;Slama, Natalie E;Penfold, Robert B;Nugent, Joshua R;Spalding, Scott R;Sterling, Stacy A;Iturralde, Esti

Acad Pediatr. 2024 Mar 06.

PubMed abstract

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