Lisa A. Croen, PhD

People

Autism Intervention Research Network on Physical Health

Establish an interdisciplinary Autism Intervention Research Network on Physical Health node that will lead, promote, and coordinate national research activities to improve the physical health and well-being of individuals with autism spectrum disorder across the lifespan, including children and adolescents as they transition to adulthood. The focus of this node is gender, sexuality, and reproductive health of autistic adults. Projects include needs assessments, design of multi-site intervention research studies, small grants funding to facilitate training and mentorship to diverse new investigators, and publication of annual research supplement.
Investigator: Croen, Lisa
Funder: Health Resources and Services Administration

Autism Specific Patterns of DNA Methylation from Birth to Age 5

This study will examine potential differences in DNA methylation (DNAm) in early life, from birth through age 5, between children who are ultimately diagnosed with autism spectrum disorder and those typically developing. Results from this work will inform whether a large-scale effort for evaluating longitudinal DNAm and epigenetic clock changes in ASD is necessary.
Investigator: Croen, Lisa
Funder: National Institute of Child Health and Human Development

Maternal Health in Pregnancy and Autism Risk - Genetic and Non-genetic Mechanisms

This study will systematically identify maternal diagnoses in pregnancy associated with autism spectrum disorder (ASD) in offspring; test if the association between maternal diagnoses and ASD is due to shared genetic factors using family data; and test the association between maternal diagnoses in pregnancy and child’s genetic liability for ASD.
Investigator: Croen, Lisa
Funder: National Institute of Mental Health

COVID-19 Response Grant

Adults with intellectual or developmental disabilities may be especially impacted by the ways the COVID-19 pandemic has led to drastic changes in usual daily routines and the way healthcare encounters have been transitioned to virtual (video, telephone) visits. This project will characterize healthcare utilization and health status among adults with autism spectrum disorders (ASD) during the COVID-19 pandemic, comparing to similar indices in the pre-COVID period. Among adults with chronic health conditions that require ongoing management (such as diabetes, heart disease, or mental health conditions), we will also compare healthcare utilization between adults with and without ASD.
Investigator: Croen, Lisa
Funder: Special Hope Foundation

Maternal Inflammation during Pregnancy and Neurodevelopmental Disorders

​This study will utilize the Pregnancy Cohort from the Kaiser Permanente Northern California Research Program on Genes, Environment and Health to characterize the maternal immune profile over pregnancy and evaluate whether there are specific longitudinal patterns that are associated with neurodevelopmental outcomes in the offspring. The project will identify factors that are associated with longitudinal patterns of maternal immune markers over pregnancy and examine whether there is variability in risk factors across different neurodevelopmental outcomes. Factors to be examined include maternal demographic, lifestyle, clinical, and genetic factors.
Investigator: Croen, Lisa
Funder: National Institute of Child Health and Human Development

Optimizing Social Communication Measurement with the Social Responsiveness Scale

​This project aims to: 1) compare the psychometric characteristics (including distributional properties, agreement with gold-standard diagnostic measures, and sensitivity and specificity) of short versus full Social Responsiveness Scale (SRS) scores, using existing child SRS data from the Environmental influences on Child Health Outcomes (ECHO) study; 2) use existing SRS data in ECHO to compare the performance of short versus full SRS scores in analyses of established risk factors for autism spectrum disorder (gestational age and parental age), as well as in assessment of familiality of scores (previously established for the full scale) in cohorts with available parental scores; and 3) A) develop a computer-adaptive testing (CAT)-based SRS, and B) conduct a separate validation of the 16-item short form administered as a standalone questionnaire (rather than relying on short form scores derived from responses to the full SRS) and of the newly developed CAT-based SRS in separate clinical and general population samples of children aged 3 to 5 years.
Investigator: Croen, Lisa
Funder: National Institutes of Health, Office of the Director

Autism Adaptive Community-Based Treatment to Improve Outcomes Using Navigators (ACTION) Network

One of the greatest challenges in autism treatment is how to bridge the health care science-to-service gap and address disparities in access to evidence-based early intervention for children with autism spectrum disorder. This project will establish a new interdisciplinary network of eight institutions to blend implementation and clinical effectiveness research designs, with an overarching aim to study the individual and combined effects of three intervention components: 1) Infusing mobile technology for professional development and family education using the Autism Navigator collection of web-based courses and tools; 2) Engaging families to access resources and support when they first learn their child has autism spectrum disorder, using a brief engagement intervention by community healthcare workers as family navigators to accelerate access to care; and 3) Coaching families to embed evidence-based intervention strategies in everyday activities using the Early Social Interaction Parent Coaching model to improve outcomes for toddlers with autism spectrum disorder.
Investigator: Croen, Lisa
Funder: National Institutes of Health

Barriers to Health Care in a Latino Population with Autism Spectrum Disorder

This study will identify barriers to the use of recommended assessment, diagnostic, and treatment services among Latino children and adolescents with autism spectrum disorder. The study population will comprise Kaiser Permanente Northern California Latino members, and comparisons will be made between commercially insured versus federally insured (Medicaid) patients, and English versus Spanish speakers.
Investigator: Croen, Lisa; Gordon, Nancy
Funder: Northern California Community Benefit Programs

Prenatal Exposure to Metals and Risk for Autism Spectrum Disorder in MARBLES and EARLI

The peri-conceptual and prenatal periods of gestation are the most likely window of susceptibility for ASD; thus, maternal exposures and maternal genetic susceptibility are critical targets of investigation. Maternal exposure to heavy metals has been recognized for many years as a cause of fetal harm, particularly neurodevelopmental. In this study, we combine two prospective, enriched risk, pregnancy cohorts with available pregnancy and birth biosamples for metals and genetic measurement, with early-life developmental phenotype data, with age 3 ASD diagnosis status assessed by ASD researchers, and enough outcomes to provide adequate power given the enriched design. Further, we consider the utility of epigenetic measures in the study of these environmental risk factors, given evidence of the susceptibility of DNA methylation changes from metals exposure and the potential role of DNA methylation as a mediator of ASD risk or as a post-natal biomarker of metals exposure.
Investigator: Croen, Lisa
Funder: National Institute of Environmental Health Sciences

Health System Integration of Tools to Improve Primary Care for Autistic Adults

The objective of this project is to use a CBPR approach to understand how to best integrate the AASPIRE Healthcare Toolkit, an online healthcare toolkit aimed at improving primary care services for autistic adults, into the KP Northern CA healthcare system as we prepare for the larger effectiveness-implementation trial. We will do so by achieving the following specific aims: 1) To determine how to integrate use of the toolkit into the Kaiser systems. 2) To assess the acceptability and feasibility of both the intervention and the research protocols. 3) To further explore potential mechanisms of action.
Investigator: Croen, Lisa
Funder: National Institute of Mental Health

Understanding Family Economic Impact of Chronic Child Health Conditions

This study will address an important knowledge gap by estimating financial and time costs for families of children with autism. We will recruit 1,500 families of children 3-17 years old from geographically and ethnically diverse integrated health systems: Kaiser Permanente Northwest, Kaiser Permanente Northern California, Kaiser Permanente Georgia, Kaiser Permanente Hawaii and the OCHIN network of federally qualified health plans. Using the Family Economic Impact Interview, we will follow participating families for one year to collect information on family costs and examine what factors contribute to these costs.
Investigator: Croen, Lisa
Funder: National Institute of Child Health and Human Development

Prenatal SSRI Exposure, Maternal and Child Genotype, and Autism Spectrum Disorders

The prevalence of Autism Spectrum Disorders (ASD) has increased rapidly over recent decades. Among many environmental exposures that have also increased in frequency is the use of anti-depressant medications during pregnancy. Approximately 10% of pregnant women are prescribed selective seratonin reuptake inhibitors (SSRIs) SSRIs and other anti-depressant medication cross the placenta and are secreted in breast milk, thus raising concerns about adverse effects on the fetus or infant. This study will expand upon previous findings of an association between prenatal SSRI exposure and autism risk by utilizing data and biospecimens already collected in the SEED study to explore main and joint effects of maternal antidepressant use, maternal psychiatric disease history, and maternal and child genetic susceptibility.
Investigator: Croen, Lisa
Funder: National Institute of Child Health and Human Development

Prospective Evaluation of Air Pollution, Cognition and Autism from Birth Onward

This study will examine the relationship between perinatal and early life air pollution exposure and early longitudinal measures of cognitive ability and ASD in two prospective samples - Markers of Autism Risk in Babies, Learning Early Signs (MARBLES) and Early Autism Risk Longitudinal Investigation (EARLI). Aim 1 is to assign air pollutant exposure using geographic information systems (GIS) technology and novel biomarker measurements. Aim 2 is to examine the effect of air pollutant exposure on the trajectory of cognitive development. Aim 3 is to evaluate the effect of air pollution exposure on cross-sectional and longitudinal measures of autistic traits and ASD diagnoses.
Investigator: Croen, Lisa
Funder: National Institute of Environmental Health Sciences

Neurodevelopment of Cognitive Control in Autism: Adolescence to Young Adulthood

This study compares the developmental trajectory of behavioral measures of cognitive control from adolescence into young adulthood in typical individuals (TYP) and individuals with Autism Spectrum Disorder (ASD). We predict that approximately 2/3 of those with ASD will show a persistent lag in performance on cognitive control tasks through young adulthood, and that in those with ASD, cognitive control abilities will predict performance in complex information processing. We will also examine the development of the neural mechanisms of cognitive control from adolescence to young adulthood. We hypothesize that those with ASD will employ more reactive cognitive control than their TYP counterparts. Lastly, we will investigate relationships between the two modes of cognitive control, and functional and mental health outcomes between adolescence and young adulthood in the ASD group.
Investigator: Croen, Lisa
Funder: National Institute of Mental Health

Folic Acid Prevention Pathways for ASD in High Risk Families

Autism spectrum disorders affect 1 in 68 children in the US. There is evidence for a potentially large role for the early in-utero environment, including gestational nutrition, in ASD etiology. Maternal folic acid is one of the first modifiable factors with the potential to reduce occurrence of ASD. In addition to being essential for neurodevelopment, folate is a primary methyl-donor for methylation reactions. The time near conception is an especially critical period for adequate methyl supply during cycles of active de-methylation and re-methylation during embryogenesis, interactions with genetic and environmental risk factors, and the greatest reduction in ASD risk associated with higher maternal folic acid intake. Using data and samples from mother-child pairs in two large prospective studies, this study proposes to examine specific pathways for prevention of ASD through maternal dietary and supplemental folate intake.
Investigator: Croen, Lisa
Funder: National Institute of Environmental Health Sciences

Early Life Exposure to Endocrine Disrupting Chemicals and Child Growth, Adiposity, and Neurodevelopment

We hypothesize that in-utero exposures to commonly used endocrine disrupting chemicals, such as PFCs and PBDEs, individually and/or in combination, have adverse effects on child obesity and neurodevelopment through possible common pathways. Our aims are: Aim 1. To evaluate whether in-utero exposures to maternal PFCs and PBDEs, individually and/or in combination, are associated with infant growth, adiposity and neurodevelopment. Aim 2. To evaluate whether in-utero PFCs and PBDEs exposures are associated with metabolic determinants of obesity and neurodevelopment . Aim 3. To explore whether in-utero PFCs and PBDEs exposures are associated with infant patterns of DNA methylation. Aim 4. To identify infant, maternal and paternal factors that modify the association of exposure to in-utero PFCs and PBDEs exposures and with infant growth, adiposity and neurodevelopment.
Investigator: Croen, Lisa; Ferrara, Assiamira
Funder: National Institutes of Health

Role of Pre-natal Vitamin D and Gene Interactions in Autism Spectrum Disorders: Leveraging an Existing Case-Control Study

This study is the first to investigate the role of perinatal vitamin D deficiency or insufficiency in ASD etiology, as modulated by race and genes involved in vitamin D metabolism and receptor activity, in a large, racially-diverse cohort. The role of vitamin D in a number of health conditions has gained recent attention, concurrent with high frequency of vitamin D deficiency/insufficiency being documented, attributed to changes in lifestyle. Evidence indicating higher risk of autism by factors shown to be related to lower vitamin D levels and recent advances in the understanding of the role of vitamin D on brain and immune function support a potential role in autism etiology that warrants rigorous investigation. A few studies of children with autism (or their mothers) have found lower vitamin D levels, but they all were limited by small samples and measurement of levels after the critical period of brain development.
Investigator: Croen, Lisa
Funder: National Institute of Child Health and Human Development

California CADDRE-SEED Phase II

The goal of this project is to continue the SEED study, a case-control study of genetic and environmental risk factors for autism. The major goal of the project is to conduct a multi-site collaborative epidemiologic study to investigate risk and causal factors for Autism Spectrum Disorders (ASD) and phenotypic subgroups of ASD using a population-based case-cohort study design.
Investigator: Croen, Lisa
Funder: Centers for Disease Control and Prevention

No results found matching criteria

The Association of Prenatal Vitamins and Folic Acid Supplement Intake with Odds of Autism Spectrum Disorder in a High-Risk Sibling Cohort, the Early Autism Risk Longitudinal Investigation (EARLI)

Author(s): Brieger KK; Bakulski KM; Pearce CL; Baylin A; Dou JF; Feinberg JI; Croen LA; Hertz-Picciotto I; Newschaffer CJ; Fallin MD; Schmidt RJ

J Autism Dev Disord. 2021 Jun 10.

PubMed abstract

Maternal Psychiatric Conditions, Treatment With Selective Serotonin Reuptake Inhibitors, and Neurodevelopmental Disorders

Author(s): Ames JL; Croen LA; et al.

Biol Psychiatry. 2021 Apr 14.

PubMed abstract

Maternal blood metal concentrations and whole blood DNA methylation during pregnancy in the Early Autism Risk Longitudinal Investigation (EARLI)

Author(s): Aung MT; Croen LA; Fallin MD; et al.

Epigenetics. 2021 Apr 02:1-16.

PubMed abstract

Maternal health around pregnancy and autism risk: a diagnosis-wide, population-based study

Author(s): Kodesh A; Croen L; Janecka M; et al.

Psychol Med. 2021 Mar 26:1-9.

PubMed abstract

A profile and review of findings from the Early Markers for Autism study: unique contributions from a population-based case-control study in California

Author(s): Lyall K; Ames JL; Croen LA; et al.

Mol Autism. 2021 Mar 18;12(1):24. Epub 2021-03-18.

PubMed abstract

Evaluation of sex differences in preschool children with and without autism spectrum disorder enrolled in the study to explore early development

Author(s): Wiggins LD; Croen L; Schieve L; et al.

Res Dev Disabil. 2021 Feb 17;112:103897. Epub 2021-02-17.

PubMed abstract

Bayesian Weighted Sums: A Flexible Approach to Estimate Summed Mixture Effects

Author(s): Hamra GB; Maclehose RF; Croen L; Kauffman EM; Newschaffer C

Int J Environ Res Public Health. 2021 Feb 03;18(4). Epub 2021-02-03.

PubMed abstract

Gestational Exposure to Phthalates and Social Responsiveness Scores in Children Using Quantile Regression: The EARLI and HOME Studies

Author(s): Patti MA; Croen LA; Braun JM; et al.

Int J Environ Res Public Health. 2021 Jan 30;18(3). Epub 2021-01-30.

PubMed abstract

Association between self-reported caffeine intake during pregnancy and social responsiveness scores in childhood: The EARLI and HOME studies

Author(s): Patti MA; Croen LA; Braun JM; et al.

PLoS One. 2021;16(1):e0245079. Epub 2021-01-15.

PubMed abstract

Gastrointestinal Symptoms in 2- to 5-Year-Old Children in the Study to Explore Early Development

Author(s): Reynolds AM; Croen LA; Levy SE; et al.

J Autism Dev Disord. 2021 Jan 04.

PubMed abstract

Maternal immune response and air pollution exposure during pregnancy: insights from the Early Markers for Autism (EMA) study

Author(s): Volk HE; Alexeeff SE; Croen LA; et al.

J Neurodev Disord. 2020 Dec 16;12(1):42. Epub 2020-12-16.

PubMed abstract

Prenatal Multivitamin Use and MTHFR Genotype Are Associated with Newborn Cord Blood DNA Methylation

Author(s): Bakulski KM; Dou JF; Feinberg JI; Brieger KK; Croen LA; Hertz-Picciotto I; Newschaffer CJ; Schmidt RJ; Fallin MD

Int J Environ Res Public Health. 2020 Dec 09;17(24). Epub 2020-12-09.

PubMed abstract

Meconium androgens are correlated with ASD-related phenotypic traits in early childhood in a familial enriched risk cohort

Author(s): Terloyeva D; Croen LA; Snyder NW; et al.

Mol Autism. 2020 Nov 23;11(1):93. Epub 2020-11-23.

PubMed abstract

Maternal Vitamin D Levels During Pregnancy in Association With Autism Spectrum Disorders (ASD) or Intellectual Disability (ID) in Offspring; Exploring Non-linear Patterns and Demographic Sub-groups

Author(s): Windham GC; Pearl M; Poon V; Berger K; Soriano JW; Eyles D; Lyall K; Kharrazi M; Croen LA

Autism Res. 2020 Nov 02.

PubMed abstract

Psychometric testing of a set of patient-reported instruments to assess healthcare interventions for autistic adults

Author(s): Nicolaidis C; Zhen KY; Lee J; Raymaker DM; Kapp SK; Croen LA; Urbanowicz A; Maslak J; Scharer M

Autism. 2020 Oct 25:1362361320967178.

PubMed abstract

Prenatal Air Pollution Exposure and Neurodevelopment: A Review and Blueprint for a Harmonized Approach within ECHO

Author(s): Volk HE; Croen LA; Environmental influences on Child Health Outcomes; et al.

Environ Res. 2020 Oct 21:110320.

PubMed abstract

Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes

Author(s): Mordaunt CE; Zhu Y; Croen LA; LaSalle JM; et al.

Genome Med. 2020 Oct 14;12(1):88. Epub 2020-10-14.

PubMed abstract

Distributional Properties and Criterion Validity of a Shortened Version of the Social Responsiveness Scale: Results from the ECHO Program and Implications for Social Communication Research

Author(s): Lyall K; Croen LA; program collaborators for Environmental influences on Child Health Outcomes; et al.

J Autism Dev Disord. 2020 Sep 17.

PubMed abstract

Factors Influencing Participation in Biospecimen Research among Parents of Youth with Mental Health Conditions

Author(s): Owen-Smith AA; Sesay MM; Lynch FL; Massolo M; Cerros H; Croen LA

Public Health Genomics. 2020 Jul 22:1-11.

PubMed abstract

The Association Between Maternal Prenatal Fish Intake and Child Autism-Related Traits in the EARLI and HOME Studies

Author(s): Vecchione R; Croen LA; Irva Hertz-Picciotto; Lyall K; et al.

J Autism Dev Disord. 2020 Jun 09.

PubMed abstract

Healthcare service utilization and cost among transition-age youth with autism spectrum disorder and other special healthcare needs

Author(s): Ames JL; Massolo ML; Davignon MN; Qian Y; Croen LA

Autism. 2020 Jun 25:1362361320931268.

PubMed abstract

Transitioning youth with autism spectrum disorders and other special health care needs into adult primary care: A provider survey

Author(s): Ames JL; Massolo ML; Davignon MN; Qian Y; Cerros HJ; Croen LA

Autism. 2020 Jun 18:1362361320926318.

PubMed abstract

Community-based service use in preschool children with autism spectrum disorder and associations with insurance status

Author(s): Rubenstein E; Croen L; Lee LC; Moody E; Schieve LA; Soke GN; Thomas K; Wiggins L; Daniels J

Res Autism Spectr Disord. 2019 Oct;66. Epub 2019-06-15.

PubMed abstract

The Association Between Parental Age and Autism-Related Outcomes in Children at High Familial Risk for Autism

Author(s): Lyall K; Croen LA; Volk HE; et al.

Autism Res. 2020 Apr 21.

PubMed abstract

Genetic Contributions to Maternal and Neonatal Vitamin D Levels

Author(s): Traglia M; Windham GC; Pearl M; Poon V; Eyles D; Jones KL; Lyall K; Kharrazi M; Croen LA; Weiss LA

Genetics. 2020 Feb 11.

PubMed abstract

Neonatal Thyroid Stimulating Hormone and Subsequent Diagnosis of Autism Spectrum Disorders and Intellectual Disability

Author(s): Ames JL; Windham GC; Lyall K; Pearl M; Kharrazi M; Yoshida CK; Van de Water J; Ashwood P; Croen LA

Autism Res. 2019 Dec 10.

PubMed abstract

A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in umbilical cord blood

Author(s): Mordaunt CE; Croen LA; Fallin MD; et al.

Mol Autism. 2019;10:36. Epub 2019-10-24.

PubMed abstract

Early Life Exposure to Air Pollution and Autism Spectrum Disorder: Findings from a Multisite Case-Control Study

Author(s): McGuinn LA; Croen LA; Daniels JL; et al.

Epidemiology. 2019 Oct 01.

PubMed abstract

Air pollution, neighborhood deprivation, and autism spectrum disorder in the Study to Explore Early Development

Author(s): McGuinn LA; Croen LA; Daniels JL; et al.

Environ Epidemiol. 2019 Oct;3(5).

PubMed abstract

Prenatal Opioid Exposure: Neurodevelopmental Consequences and Future Research Priorities

Author(s): Conradt E; Croen LA; Hedderson MM; Lester BM; et al.

Pediatrics. 2019 Sep;144(3).

PubMed abstract

Neonatal jaundice in association with autism spectrum disorder and developmental disorder

Author(s): Cordero C; Schieve LA; Croen LA; Engel SM; Maria Siega-Riz A; Herring AH; Vladutiu CJ; Seashore CJ; Daniels JL

J Perinatol. 2019 Aug 06.

PubMed abstract

Infection and Fever in Pregnancy and Autism Spectrum Disorders: Findings from the Study to Explore Early Development

Author(s): Croen LA; Qian Y; Zerbo O; Ames JL; et al.

Autism Res. 2019 Jul 17.

PubMed abstract

An Exploratory Examination of Neonatal Cytokines and Chemokines as Predictors of Autism Risk: The Early Markers for Autism Study

Author(s): Heuer LS; Croen LA; Jones KL; Yoshida CK; Hansen RL; Yolken R; Zerbo O; DeLorenze G; Kharrazi M; Ashwood P; Van de Water J

Biol Psychiatry. 2019 May 15.

PubMed abstract

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Author(s): Küpers LK; Croen LA; Felix JF; et al.

Nat Commun. 2019 04 23;10(1):1893. Epub 2019-04-23.

PubMed abstract

Maternal diabetes and hypertensive disorders in association with autism spectrum disorder

Author(s): Cordero C; Windham GC; Schieve LA; Fallin MD; Croen LA; Siega-Riz AM; Engel SM; Herring AH; Stuebe AM; Vladutiu CJ; Daniels JL

Autism Res. 2019 Apr 10.

PubMed abstract

Newborn vitamin D levels in relation to autism spectrum disorders and intellectual disability: A case-control study in california

Author(s): Windham GC; Pearl M; Anderson MC; Poon V; Eyles D; Jones KL; Lyall K; Kharrazi M; Croen LA

Autism Res. 2019 Mar 18.

PubMed abstract

Epigenetic marks of prenatal air pollution exposure found in multiple tissues relevant for child health

Author(s): Ladd-Acosta C; Feinberg JI; Brown SC; Lurmann FW; Croen LA; Hertz-Picciotto I; Newschaffer CJ; Feinberg AP; Fallin MD; Volk HE

Environ Int. 2019 May;126:363-376. Epub 2019-02-28.

PubMed abstract

Prenatal exposure to endocrine disrupting chemicals in relation to autism spectrum disorder and intellectual disability

Author(s): Hamra GB; Lyall K; Windham GC; Calafat AM; Sjödin A; Volk H; Croen LA

Epidemiology. 2019 Feb 15.

PubMed abstract

Infections in children with autism spectrum disorder: Study to Explore Early Development (SEED)

Author(s): Sabourin KR; Reynolds A; Schendel D; Rosenberg S; Croen LA; Pinto-Martin JA; Schieve LA; Newschaffer C; Lee LC; DiGuiseppi C

Autism Res. 2018 Nov 26.

PubMed abstract

Cross-genetic determination of maternal and neonatal immune mediators during pregnancy

Author(s): Traglia M; Croen LA; Jones KL; Heuer LS; Yolken R; Kharrazi M; DeLorenze GN; Ashwood P; Van de Water J; Weiss LA

Genome Med. 2018 Aug 22;10(1):67. Epub 2018-08-22.

PubMed abstract

Placental gross shape differences in a high autism risk cohort and the general population

Author(s): Park BY; Misra DP; Moye J; Miller RK; Croen L; Fallin MD; Walker C; Newschaffer CJ; Salafia CM; National Children’s Study Consortium

PLoS ONE. 2018;13(8):e0191276. Epub 2018-08-22.

PubMed abstract

Brief Report: Maternal Opioid Prescription from Preconception Through Pregnancy and the Odds of Autism Spectrum Disorder and Autism Features in Children

Author(s): Rubenstein E; Young JC; Croen LA; DiGuiseppi C; Dowling NF; Lee LC; Schieve L; Wiggins LD; Daniels J

J Autism Dev Disord. 2018 Aug 21.

PubMed abstract

Brief Report: Low Rates of Herpesvirus Detection in Blood of Individuals with Autism Spectrum Disorder and Controls

Author(s): Sweeten TL; Croen LA; Windham GC; Odell JD; Stubbs EG; Torres AR

J Autism Dev Disord. 2018 Jul 25.

PubMed abstract

Case-control meta-analysis of blood DNA methylation and autism spectrum disorder

Author(s): Andrews SV; Croen LA; Ladd-Acosta C; et al.

Mol Autism. 2018;9:40. Epub 2018-06-28.

PubMed abstract

Psychiatric and Medical Conditions in Transition-Aged Individuals With ASD

Author(s): Davignon MN; Qian Y; Massolo M; Croen LA

Pediatrics. 2018 Apr;141(Suppl 4):S335-S345.

PubMed abstract

Cord blood buffy coat DNA methylation is comparable to whole cord blood methylation

Author(s): Dou J; Schmidt RJ; Benke KS; Newschaffer C; Hertz-Picciotto I; Croen LA; Iosif AM; LaSalle JM; Fallin MD; Bakulski KM

Epigenetics. 2018 Feb 16:1-9.

PubMed abstract

Associations Between the 2nd to 4th Digit Ratio and Autism Spectrum Disorder in Population-Based Samples of Boys and Girls: Findings from the Study to Explore Early Development

Author(s): Schieve LA; Tian L; Dowling N; Croen L; Hoover-Fong J; Alexander A; Shapira SK

J Autism Dev Disord. 2018 Feb 15.

PubMed abstract

Prenatal Maternal Serum Concentrations of Per- and Polyfluoroalkyl Substances in Association with Autism Spectrum Disorder and Intellectual Disability

Author(s): Lyall K; Yau VM; Hansen R; Kharrazi M; Yoshida CK; Calafat AM; Windham G; Croen LA

Environ Health Perspect. 2018 Jan 02;126(1):017001. Epub 2018-01-02.

PubMed abstract

Autism risk classification using placental chorionic surface vascular network features

Author(s): Chang JM; Zeng H; Han R; Chang YM; Shah R; Salafia CM; Newschaffer C; Miller RK; Katzman P; Moye J; Fallin M; Walker CK; Croen L

BMC Med Inform Decis Mak. 2017 Dec 06;17(1):162. Epub 2017-12-06.

PubMed abstract

Autism spectrum disorder and birth spacing: Findings from the study to explore early development (SEED)

Author(s): Schieve LA; Tian LH; Drews-Botsch C; Windham GC; Newschaffer C; Daniels JL; Lee LC; Croen LA; Danielle Fallin M

Autism Res. 2017 Nov 22.

PubMed abstract

Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder

Author(s): Andrews SV; Ellis SE; Bakulski KM; Sheppard B; Croen LA; Hertz-Picciotto I; Newschaffer CJ; Feinberg AP; Arking DE; Ladd-Acosta C; Fallin MD

Nat Commun. 2017 Oct 24;8(1):1011. Epub 2017-10-24.

PubMed abstract

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium

Author(s): Sharp GC; Salas LA; Monnereau C; Allard C; Yousefi P; Everson TM; Bohlin J; Xu Z; Huang RC; Reese SE; Xu CJ; Baïz N; Hoyo C; Agha G; Roy R; Holloway JW; Ghantous A; Merid SK; Bakulski KM; Küpers LK; Zhang H; Richmond RC; Page CM; Duijts L; Lie RT; Melton PE; Vonk JM; Nohr EA; Williams-DeVane C; Huen K; Rifas-Shiman SL; Ruiz-Arenas C; Gonseth S; Rezwan FI; Herceg Z; Ekström S; Croen L; Falahi F; Perron P; Karagas MR; Quraishi BM; Suderman M; Magnus MC; Jaddoe VWV; Taylor JA; Anderson D; Zhao S; Smit HA; Josey MJ; Bradman A; Baccarelli AA; Bustamante M; Håberg SE; Pershagen G; Hertz-Picciotto I; Newschaffer C; Corpeleijn E; Bouchard L; Lawlor DA; Maguire RL; Barcellos LF; Davey Smith G; Eskenazi B; Karmaus W; Marsit CJ; Hivert MF; Snieder H; Fallin MD; Melén E; Munthe-Kaas MC; Arshad H; Wiemels JL; Annesi-Maesano I; Vrijheid M; Oken E; Holland N; Murphy SK; Sørensen TIA; Koppelman GH; Newnham JP; Wilcox AJ; Nystad W; London SJ; Felix JF; Relton CL

Hum Mol Genet. 2017 Oct 15;26(20):4067-4085.

PubMed abstract

Scaling of the surface vasculature on the human placenta

Author(s): Leonard AS; Lee J; Schubert D; Croen LA; Fallin MD; Newschaffer CJ; Walker CK; Salafia CM; Morgan SP; Vvedensky DD

Phys Rev E. 2017 Oct;96(4-1):040401. Epub 2017-10-02.

PubMed abstract

Maternal and Paternal Infertility Disorders and Treatments and Autism Spectrum Disorder: Findings from the Study to Explore Early Development

Author(s): Schieve LA; Drews-Botsch C; Harris S; Newschaffer C; Daniels J; DiGuiseppi C; Croen LA; Windham GC

J Autism Dev Disord. 2017 Sep 12.

PubMed abstract

Prenatal Alcohol Exposure in Relation to Autism Spectrum Disorder: Findings from the Study to Explore Early Development (SEED)

Author(s): Singer AB; Aylsworth AS; Cordero C; Croen LA; DiGuiseppi C; Fallin MD; Herring AH; Hooper SR; Pretzel RE; Schieve LA; Windham GC; Daniels JL

Paediatr Perinat Epidemiol. 2017 Sep 07.

PubMed abstract

Prenatal Serum Concentrations of Brominated Flame Retardants and Autism Spectrum Disorder and Intellectual Disability in the Early Markers of Autism Study: A Population-Based Case-Control Study in California

Author(s): Lyall K; Croen LA; Weiss LA; Kharrazi M; Traglia M; Delorenze GN; Windham GC

Environ Health Perspect. 2017 Aug 30;125(8):087023. Epub 2017-08-30.

PubMed abstract

Demographic and Clinical Characteristics Associated with Engagement in Behavioral Health Treatment Among Children with Autism Spectrum Disorders

Author(s): Croen LA; Shankute N; Davignon M; Massolo ML; Yoshida C

J Autism Dev Disord. 2017 Jul 26.

PubMed abstract

A Survey of Parents with Children on the Autism Spectrum: Experience with Services and Treatments

Author(s): Becerra TA; Massolo ML; Yau VM; Owen-Smith AA; Lynch FL; Crawford PM; Pearson KA; Pomichowski ME; Quinn VP; Yoshida CK; Croen LA

Perm J. 2017;21.

PubMed abstract

Medical Conditions in the First Years of Life Associated with Future Diagnosis of ASD in Children

Author(s): Alexeeff SE; Yau V; Qian Y; Davignon M; Lynch F; Crawford P; Davis R; Croen LA

J Autism Dev Disord. 2017 Apr 22.

PubMed abstract

Independent Maternal and Fetal Genetic Effects on Mid-gestational Circulating Levels of Environmental Pollutants

Author(s): Traglia M; Croen LA; Lyall K; Windham GC; Kharrazi M; DeLorenze GN; Torres AR; Weiss LA

G3 (Bethesda). 2017 Feb 24.

PubMed abstract

Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study

Author(s): Park BY; Lee BK; Burstyn I; Tabb LP; Keelan JA; Whitehouse AJ; Croen LA; Fallin MD; Hertz-Picciotto I; Montgomery O; Newschaffer CJ

Mol Autism. 2017;8:3. Epub 2017-01-31.

PubMed abstract

The Changing Epidemiology of Autism Spectrum Disorders

Author(s): Lyall K; Croen L; Daniels J; Fallin MD; Ladd-Acosta C; Lee BK; Park BY; Snyder NW; Schendel D; Volk HE; Windham GC; Newschaffer C

Annu Rev Public Health. 2016 Dec 21.

PubMed abstract

The Kaiser Permanente Northern California research program on genes, environment, and health (RPGEH) pregnancy cohort; study design, methodology and baseline characteristics.

Author(s): Hedderson MM; Ferrara A; Avalos LA; Van den Eeden SK; Gunderson EP; Li DK; Altschuler A; Woo S; Rowell S; Choudhary V; Xu F; Flanagan T; Schaefer C; Croen LA;

​BMC Pregnancy Childbirth. 2016 Nov 29;16(1):381.

PubMed abstract

Association Between Influenza Infection and Vaccination During Pregnancy and Risk of Autism Spectrum Disorder

Author(s): Zerbo O; Qian Y; Yoshida C; Fireman BH; Klein NP; Croen LA

JAMA Pediatr. 2016 Nov 28.

PubMed abstract

Differences in testosterone and its precursors by sex of the offspring in meconium

Author(s): Frey AJ; Park BY; Schriver ER; Feldman DR; Parry S; Croen LA; Fallin DM; Hertz-Picciotto I; Newschaffer CJ; Snyder NW

J Steroid Biochem Mol Biol. 2016 Nov 18.

PubMed abstract

Psychotropic Medication Use among Insured Children with Autism Spectrum Disorder

Author(s): Madden JM; Lakoma MD; Lynch FL; Rusinak D; Owen-Smith AA; Coleman KJ; Quinn VP; Yau VM; Qian YX; Croen LA

J Autism Dev Disord. 2016 Nov 5.

PubMed abstract

Pleiotropic Mechanisms Indicated for Sex Differences in Autism

Author(s): Mitra I; Tsang K; Ladd-Acosta C; Croen LA; Aldinger KA; Hendren RL; Traglia M; Lavillaureix A; Zaitlen N; Oldham MC; Levitt P; Nelson S; Amaral DG; Herz-Picciotto I; Fallin MD; Weiss LA

PLoS Genet. 2016 Nov;12(11):e1006425. Epub 2016-11-15.

PubMed abstract

Risk of Autism Associated With Hyperbilirubinemia and Phototherapy

Author(s): Wu YW; Kuzniewicz MW; Croen L; Walsh EM; McCulloch CE; Newman TB

Pediatrics. 2016 Sep 26.

PubMed abstract

Polychlorinated Biphenyl and Organochlorine Pesticide Concentrations in Maternal Mid-Pregnancy Serum Samples: Association with Autism Spectrum Disorder and Intellectual Disability

Author(s): Lyall K; Croen LA; Sj?din A; Yoshida CK; Zerbo O; Kharrazi M; Windham GC

Environ Health Perspect. 2016 Aug 23.

PubMed abstract

Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development

Author(s): Singer AB; Windham GC; Croen LA; Daniels JL; Lee BK; Qian Y; Schendel DE; Fallin MD; Burstyn I

J Autism Dev Disord. 2016 Aug 10.

PubMed abstract

Evaluating Changes in the Prevalence of the Autism Spectrum Disorders (ASDs)

Author(s): Rice CE; Rosanoff M; Dawson G; Durkin MS; Croen LA; Singer A; Yeargin-Allsopp M

Public Health Rev. 2012;34(2):1-22.

PubMed abstract

The autism symptom interview, school-age: A brief telephone interview to identify autism spectrum disorders in 5-to-12-year-old children

Author(s): Bishop SL; Huerta M; Gotham K; Alexandra Havdahl K; Pickles A; Duncan A; Hus Bal V; Croen L; Lord C

Autism Res. 2016 Jun 10.

PubMed abstract

Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation

Author(s): Jones KL; Croen LA; Yoshida CK; Heuer L; Hansen R; Zerbo O; DeLorenze GN; Kharrazi M; Yolken R; Ashwood P; Van de Water J

Mol Psychiatry. 2016 May 24.

PubMed abstract

Prenatal and Newborn Immunoglobulin Levels from Mother-Child Pairs and Risk of Autism Spectrum Disorders

Author(s): Grether JK; Ashwood P; Van de Water J; Yolken RH; Anderson MC; Torres AR; Westover JB; Sweeten T; Hansen RL; Kharrazi M; Croen LA

Front Neurosci. 2016;10:218. Epub 2016-05-18.

PubMed abstract

​Maternal mid-pregnancy C-reactive protein and risk of autism spectrum disorders: the early markers for autism study

Author(s): Zerbo O; Traglia M; Yoshida C; Heuer LS; Ashwood P; Delorenze GN; Hansen RL; Kharrazi M; Van de Water J; Yolken RH; Weiss LA; Croen LA;

​Transl Psychiatry. 2016 Apr 19;6:e783. doi: 10.1038/tp.2016.46.

PubMed abstract

Demographic profile of families and children in the Study to Explore Early Development (SEED): Case-control study of autism spectrum disorder

Author(s): DiGuiseppi CG; Daniels JL; Fallin DM; Rosenberg SA; Schieve LA; Thomas KC; Windham GC; Goss CW; Soke GN; Currie DW; Singer AB; Lee LC; Bernal P; Croen LA; Miller LA; Pinto-Martin JA; Young LM; Schendel DE

Disabil Health J. 2016 Jan 29.

PubMed abstract

Peripheral Blood Leukocyte Production of BDNF following Mitogen Stimulation in Early Onset and Regressive Autism

Author(s): Enstrom A; Onore C; Tarver A; Hertz-Picciotto I; Hansen R; Croen L; Van de Water J; Ashwood P

Am J Biochem Biotechnol. 2008;4(2):121-129.

PubMed abstract

Presence of an epigenetic signature of prenatal cigarette smoke exposure in childhood

Author(s): Ladd-Acosta C; Shu C; Lee BK; Gidaya N; Singer A; Schieve LA; Schendel DE; Jones N; Daniels JL; Windham GC; Newschaffer CJ; Croen LA; Feinberg AP; Daniele Fallin M

Environ Res. 2015 Nov 20;144(Pt A):139-148. Epub 2015-11-20.

PubMed abstract

Health Services Utilization Among Children With and Without Autism Spectrum Disorders

Author(s): Cummings JR; Lynch FL; Rust KC; Coleman KJ; Madden JM; Owen-Smith AA; Yau VM; Qian Y; Pearson KA; Crawford PM; Massolo ML; Quinn VP; Croen LA

J Autism Dev Disord. 2015 Nov 7.

PubMed abstract

The health status of adults on the autism spectrum

Author(s): Croen LA; Zerbo O; Qian Y; Massolo ML; Rich S; Sidney S; Kripke C;

PubMed abstract

A Study of Physician Knowledge and Experience with Autism in Adults in a Large Integrated Healthcare System

Author(s): Zerbo O; Massolo ML; Qian Y; Croen LA

J Autism Dev Disord. 2015 Sep 3.

PubMed abstract

Prevalence and Predictors of Complementary and Alternative Medicine Use in a Large Insured Sample of Children with Autism Spectrum Disorders

Author(s): Owen-Smith AA; Bent S; Lynch FL; Coleman KJ; Yau VM; Pearson KA; Massolo ML; Quinn V; Croen LA

Res Autism Spectr Disord. 2015 Sep 1;17:40-51.

PubMed abstract

Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

Author(s): Kvale MN; Hesselson S; Hoffmann TJ; Cao Y; Chan D; Connell S; Croen LA; Dispensa BP; Eshragh J; Finn A; Gollub J; Iribarren C; Jorgenson E; Kushi LH; Lao R; Lu Y; Ludwig D; Mathauda GK; McGuire WB; Mei G; Miles S; Mittman M; Patil M; Quesenberry CP Jr; Ranatunga D; Rowell S; Sadler M; Sakoda LC; Shapero M; Shen L; Shenoy T; Smethurst D; Somkin CP; Van Den Eeden SK; Walter L; Wan E; Webster T; Whitmer RA; Wong S; Zau C; Zhan Y; Schaefer C; Kwok PY; Risch N;

​​Genetics. 2015 Aug;200(4):1051-60. doi: 10.1534/genetics.115.178905. Epub 2015 Jun 19.

PubMed abstract

Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

Author(s): Lapham K; Kvale MN; Lin J; Connell S; Croen LA; Dispensa BP; Fang L; Hesselson S; Hoffmann TJ; Iribarren C; Jorgenson E; Kushi LH; Ludwig D; Matsuguchi T; McGuire WB; Miles S; Quesenberry CP Jr; Rowell S; Sadler M; Sakoda LC; Smethurst D; Somkin CP; Van Den Eeden SK; Walter L; Whitmer RA; Kwok PY; Risch N; Schaefer C; Blackburn EH;

​Genetics. 2015 Aug;200(4):1061-72. doi: 10.1534/genetics.115.178624. Epub 2015 Jun 19.

PubMed abstract

Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

Author(s): Banda Y; Kvale MN; Hoffmann TJ; Hesselson SE; Ranatunga D; Tang H; Sabatti C; Croen LA; Dispensa BP; Henderson M; Iribarren C; Jorgenson E; Kushi LH; Ludwig D; Olberg D; Quesenberry CP Jr; Rowell S; Sadler M; Sakoda LC; Sciortino S; Shen L; Smethurst D; Somkin CP; Van Den Eeden SK; Walter L; Whitmer RA; Kwok PY; Schaefer C; Risch N;

​Genetics. 2015 Aug;200(4):1285-95. doi: 10.1534/genetics.115.178616. Epub 2015 Jun 19.

PubMed abstract

Validation of Autism Spectrum Disorder Diagnoses in Large Healthcare Systems with Electronic Medical Records

Author(s): Coleman KJ; Lutsky MA; Yau V; Qian Y; Pomichowski ME; Crawford PM; Lynch FL; Madden JM; Owen-Smith A; Pearson JA; Pearson KA; Rusinak D; Quinn VP; Croen LA

J Autism Dev Disord. 2015 Jul;45(7):1989-96.

PubMed abstract

Autism Spectrum Disorder Symptoms Among Children Enrolled in the Study to Explore Early Development (SEED)

Author(s): Wiggins LD; Levy SE; Daniels J; Schieve L; Croen LA; DiGuiseppi C; Blaskey L; Giarelli E; Lee LC; Pinto-Martin J; Reynolds A; Rice C; Rosenberg CR; Thompson P; Yeargin-Allsopp M; Young L; Schendel D

J Autism Dev Disord. 2015 Jun 6.

PubMed abstract

Immune mediated conditions in autism spectrum disorders

Author(s): Zerbo O; Leong A; Barcellos L; Bernal P; Fireman B; Croen LA

Brain Behav Immun. 2015 May;46:232-6. Epub 2015-02-11.

PubMed abstract

Paternal sperm DNA methylation associated with early signs of autism risk in an autism-enriched cohort

Author(s): Feinberg JI; Bakulski KM; Jaffe AE; Tryggvadottir R; Brown SC; Goldman LR; Croen LA; Hertz-Picciotto I; Newschaffer CJ; Daniele Fallin M; Feinberg AP

Int J Epidemiol. 2015 Apr 14.

PubMed abstract

Prenatal and Neonatal Thyroid Stimulating Hormone Levels and Autism Spectrum Disorders

Author(s): Yau VM; Lutsky M; Yoshida CK; Lasley B; Kharrazi M; Windham G; Gee N; Croen LA

J Autism Dev Disord. 2015 Mar;45(3):719-30.

PubMed abstract

Increased female autosomal burden of rare copy number variants in human populations and in autism families

Author(s): Desachy G; Croen LA; Torres AR; Kharrazi M; Delorenze GN; Windham GC; Yoshida CK; Weiss LA

Mol Psychiatry. 2015 Jan 13.

PubMed abstract

Familial Recurrence of Autism Spectrum Disorder: Evaluating Genetic and Environmental Contributions

Author(s): Risch N; Hoffmann TJ; Anderson M; Croen LA; Grether JK; Windham GC

Am J Psychiatry. 2014 Nov 1;171(11):1206-13.

PubMed abstract

Prenatal and neonatal peripheral blood mercury levels and autism spectrum disorders

Author(s): Yau VM; Green PG; Alaimo CP; Yoshida CK; Lutsky M; Windham GC; Delorenze G; Kharrazi M; Grether JK; Croen LA

Environ Res. 2014 Aug;133:294-303. Epub 2014-06-28.

PubMed abstract

Evidence of Reproductive Stoppage in Families With Autism Spectrum Disorder: A Large, Population-Based Cohort Study

Author(s): Hoffmann TJ; Windham GC; Anderson M; Croen LA; Grether JK; Risch N

JAMA Psychiatry. 2014 Aug;71(8):943-51.

PubMed abstract

Prenatal and perinatal risk factors in a twin study of autism spectrum disorders

Author(s): Froehlich-Santino W; Londono Tobon A; Cleveland S; Torres A; Phillips J; Cohen B; Torigoe T; Miller J; Fedele A; Collins J; Smith K; Lotspeich L; Croen LA; Ozonoff S; Lajonchere C; Grether JK; O'Hara R; Hallmayer J

J Psychiatr Res. 2014 Jul;54:100-8. Epub 2014-03-29.

PubMed abstract

Neonatal cytokines and chemokines and risk of Autism Spectrum Disorder: the Early Markers for Autism (EMA) study: a case-control study

Author(s): Zerbo O; Yoshida C; Grether JK; Van de Water J; Ashwood P; Delorenze GN; Hansen RL; Kharrazi M; Croen LA

J Neuroinflammation. 2014;11:113. Epub 2014-06-20.

PubMed abstract

Determining Source Strength of Semivolatile Organic Compounds using Measured Concentrations in Indoor Dust

Author(s): Shin HM; McKone TE; Nishioka MG; Fallin MD; Croen LA; Hertz-Picciotto I; Newschaffer CJ; Bennett DH

Indoor Air. 2014 Jun;24(3):260-71. Epub 2013-10-31.

PubMed abstract

Adaptation of the 'ten questions' to screen for autism and other neuro-developmental disorders in Uganda

Author(s): Kakooza-Mwesige A; Ssebyala K; Karamagi C; Kiguli S; Smith K; Anderson MC; Croen LA; Trevathan E; Hansen R; Smith D; Grether JK

Autism. 2014 May;18(4):447-57. Epub 2013-03-27.

PubMed abstract

Prevalence and Neonatal Factors Associated with Autism Spectrum Disorders in Preterm Infants

Author(s): Kuzniewicz MW; Wi S; Qian Y; Walsh EM; Armstrong MA; Croen LA

J Pediatr. 2014 Jan;164(1):20-5. Epub 2013-10-22.

PubMed abstract

Maternal Infection During Pregnancy and Autism Spectrum Disorders

Author(s): Zerbo O; Qian Y; Yoshida C; Grether JK; Van de Water J; Croen LA

J Autism Dev Disord. 2013 Dec 24.

PubMed abstract

A genome-wide survey of transgenerational genetic effects in autism

Author(s): Tsang KM; Croen LA; Torres AR; Kharrazi M; Delorenze GN; Windham GC; Yoshida CK; Zerbo O; Weiss LA

PLoS ONE. 2013;8(10):e76978. Epub 2013-10-24.

PubMed abstract

Head Circumferences in Twins With and Without Autism Spectrum Disorders

Author(s): Froehlich W; Cleveland S; Torres A; Phillips J; Cohen B; Torigoe T; Miller J; Fedele A; Collins J; Smith K; Lotspeich L; Croen LA; Ozonoff S; Lajonchere C; Grether JK; Hallmayer J

J Autism Dev Disord. 2013 Sep;43(9):2026-37.

PubMed abstract

Sequencing of the IL6 gene in a case--control study of cerebral palsy in children

Author(s): Khankhanian P; Baranzini SE; Johnson BA; Madireddy L; Nickles D; Croen LA; Wu YW

BMC Med Genet. 2013;14:126. Epub 2013-12-07.

PubMed abstract

Is Infertility Associated with Childhood Autism?

Author(s): Grether JK; Qian Y; Croughan MS; Wu YW; Schembri M; Camarano L; Croen LA

J Autism Dev Disord. 2013 Mar;43(3):663-72.

PubMed abstract

Use of Birth Certificates to Examine Maternal Occupational Exposures and Autism Spectrum Disorders in Offspring

Author(s): Windham GC; Sumner A; Li SX; Anderson M; Katz E; Croen LA; Grether JK

Autism Res. 2013 Feb;6(1):57-63. Epub 2013 Jan 29.

PubMed abstract

Genetic risk factors for perinatal arterial ischemic stroke

Author(s): Gelfand AA; Croen LA; Torres AR; Wu YW

Pediatr Neurol. 2013 Jan;48(1):36-41.

PubMed abstract

The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network

Author(s): Schendel DE; Diguiseppi C; Croen LA; Fallin MD; Reed PL; Schieve LA; Wiggins LD; Daniels J; Grether J; Levy SE; Miller L; Newschaffer C; Pinto-Martin J; Robinson C; Windham GC; Alexander A; Aylsworth AS; Bernal P; Bonner JD; Blaskey L; Bradley C; Collins J; Ferretti CJ; Farzadegan H; Giarelli E; Harvey M; Hepburn S; Herr M; Kaparich K; Landa R; Lee LC; Levenseller B; Meyerer S; Rahbar MH; Ratchford A; Reynolds A; Rosenberg S; Rusyniak J; Shapira SK; Smith K; Souders M; Thompson PA; Young L; Yeargin-Allsopp M

J Autism Dev Disord. 2012 Oct;42(10):2121-40.

PubMed abstract

Infant siblings and the investigation of autism risk factors

Author(s): Newschaffer CJ; Croen LA; Fallin MD; Hertz-Picciotto I; Nguyen DV; Lee NL; Berry CA; Farzadegan H; Hess HN; Landa RJ; Levy SE; Massolo ML; Meyerer SC; Mohammed SM; Oliver MC; Ozonoff S; Pandey J; Schroeder A; Shedd-Wise KM

J Neurodev Disord. 2012 Apr 18;4(1):7.

PubMed abstract

Prenatal exposure to beta2-adrenergic receptor agonists and risk of autism spectrum disorders

Author(s): Croen LA; Connors SL; Matevia M; Qian Y; Newschaffer C; Zimmerman AW

J Neurodev Disord. 2011 Dec;3(4):307-15. Epub 2011 Aug 27.

PubMed abstract

Candidate Genes and Risk for Cerebral Palsy: a Population-Based Study

Author(s): Wu YW; Croen LA; Vanderwerf A; Gelfand AA; Torres AR

Pediatr Res. 2011 Dec;70(6):642-6.

PubMed abstract

Antidepressant Use During Pregnancy and Childhood Autism Spectrum Disorders

Author(s): Croen LA; Grether JK; Yoshida CK; Odouli R; Hendrick V

Arch Gen Psychiatry. 2011 Nov;68(11):1104-12. Epub 2011 Jul 4.

PubMed abstract

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

Author(s): Hallmayer J; Cleveland S; Torres A; Phillips J; Cohen B; Torigoe T; Miller J; Fedele A; Collins J; Smith K; Lotspeich L; Croen LA; Ozonoff S; Lajonchere C; Grether JK; Risch N

Arch Gen Psychiatry. 2011 Nov;68(11):1095-102. Epub 2011 Jul 4.

PubMed abstract

Birth Prevalence of Autism Spectrum Disorders in the San Francisco Bay Area by Demographic and Ascertainment Source Characteristics

Author(s): Windham GC; Anderson MC; Croen LA; Smith KS; Collins J; Grether JK

J Autism Dev Disord. 2011 Oct;41(10):1362-72.

PubMed abstract

Epidemiology of peripartum cardiomyopathy: incidence, predictors, and outcomes

Author(s): Gunderson EP; Croen LA; Chiang V; Yoshida CK; Walton D; Go AS

Obstet Gynecol. 2011 Sep;118(3):583-91.

PubMed abstract

Increased midgestational IFN-gamma, IL-4 and IL-5 in women bearing a child with autism: A case-control study

Author(s): Goines PE; Croen LA; Braunschweig D; Yoshida CK; Grether J; Hansen R; Kharrazi M; Ashwood P; Van de Water J

Mol Autism. 2011 Aug 2;2:13.

PubMed abstract

Jaundice-autism link unconvincing

Author(s): Newman TB; Croen LA

Pediatrics. 2011 Mar;127(3):e858-9.

PubMed abstract

Neonatally measured immunoglobulins and risk of autism

Author(s): Grether JK; Croen LA; Anderson MC; Nelson KB; Yolken RH

Autism Res. 2010 Dec;3(6):323-32. Epub 2010 Dec 9.

PubMed abstract

Prenatal and infant exposure to thimerosal from vaccines and immunoglobulins and risk of autism

Author(s): Price CS; Thompson WW; Goodson B; Weintraub ES; Croen LA; Hinrichsen VL; Marcy M; Robertson A; Eriksen E; Lewis E; Bernal P; Shay D; Davis RL; DeStefano F

Pediatrics. 2010 Oct;126(4):656-64. Epub 2010 Sep 13.

PubMed abstract

Antenatal ultrasound and risk of autism spectrum disorders

Author(s): Grether JK; Li SX; Yoshida CK; Croen LA

J Autism Dev Disord. 2010 Feb;40(2):238-45. Epub 2009 Sep 1.

PubMed abstract

Risk of autism and increasing maternal and paternal age in a large north American population

Author(s): Grether JK; Anderson MC; Croen LA; Smith D; Windham GC

Am J Epidemiol. 2009 Nov 1;170(9):1118-26. Epub 2009 Sep 25.

PubMed abstract

Interleukin-6 genotype and risk for cerebral palsy in term and near-term infants

Author(s): Wu YW; Croen LA; Torres AR; Van De Water J; Grether JK; Hsu NN

Ann Neurol. 2009 Nov;66(5):663-70.

PubMed abstract

Investigation of shifts in autism reporting in the California Department of Developmental Services

Author(s): Grether JK; Rosen NJ; Smith KS; Croen LA

J Autism Dev Disord. 2009 Oct;39(10):1412-9. Epub 2009 May 29.

PubMed abstract

Mothers of children diagnosed with attention-deficit/hyperactivity disorder: health conditions and medical care utilization in periods before and after birth of the child

Author(s): Ray GT; Croen LA; Habel LA

Med Care. 2009 Jan;47(1):105-14.

PubMed abstract

Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes

Author(s): Ashwood P; Enstrom A; Krakowiak P; Hertz-Picciotto I; Hansen RL; Croen LA; Ozonoff S; Pessah IN; Van de Water J

J Neuroimmunol. 2008 Nov 15;204(1-2):149-53.

PubMed abstract

Maternal mid-pregnancy autoantibodies to fetal brain protein: the early markers for autism study

Author(s): Croen LA; Braunschweig D; Haapanen L; Yoshida CK; Fireman B; Grether JK; Kharrazi M; Hansen RL; Ashwood P; Van de Water J

Biol Psychiatry. 2008 Oct 1;64(7):583-8. Epub 2008 Jun 20.

PubMed abstract

Maternal Rh D status, anti-D immune globulin exposure during pregnancy, and risk of autism spectrum disorders

Author(s): Croen LA; Matevia M; Yoshida CK; Grether JK

Am J Obstet Gynecol. 2008 Sep;199(3):234.e1-6. Epub 2008 Jun 13.

PubMed abstract

Sleep problems in children with autism spectrum disorders, developmental delays, and typical development: a population-based study

Author(s): Krakowiak P; Goodlin-Jones B; Hertz-Picciotto I; Croen LA; Hansen RL

J Sleep Res. 2008 Jun;17(2):197-206.

PubMed abstract

Peripheral blood leukocyte production of BDNF following mitogen stimulation in early onset and regressive autism

Author(s): Enstrom A; Onore C; Tarver A; Hertz-Picciotto I; Hansen R; Croen L; Van de Water J; Ashwood P

Am J Biochem Biotechnology. 2008 Jun;4(2):121-9.

PubMed abstract

Detection of IL-17 and IL-23 in plasma samples of children with autism

Author(s): Enstrom A; Onore C; Hertz-Piccioto I; Hansen R; Croen L; Van de Water J; Ashwood P

Am J Biochem Biotechnology. 2008 Jun;4(2):114-20.

PubMed abstract

Brain-derived neurotrophic factor and autism: maternal and infant peripheral blood levels in the Early Markers for Autism (EMA) Study

Author(s): Croen LA; Goines P; Braunschweig D; Yolken R; Yoshida CK; Grether JK; Fireman B; Kharrazi M; Hansen RL; Van de Water J

Autism Res. 2008 Apr;1(2):130-7.

PubMed abstract

Autism: maternally derived antibodies specific for fetal brain proteins

Author(s): Braunschweig D; Ashwood P; Krakowiak P; Hertz-Picciotto I; Hansen R; Croen LA; Pessah IN; Van de Water J

Neurotoxicology. 2008 Mar;29(2):226-31. Epub 2007 Nov 6.

PubMed abstract

Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype?

Author(s): Ashwood P; Kwong C; Hansen R; Hertz-Picciotto I; Croen L; Krakowiak P; Walker W; Pessah IN; Van de Water J

J Autism Dev Disord. 2008 Jan;38(1):169-75. Epub 2007 Mar 9.

PubMed abstract

Gene expression changes in children with autism

Author(s): Gregg JP; Lit L; Baron CA; Hertz-Picciotto I; Walker W; Davis RA; Croen LA; Ozonoff S; Hansen R; Pessah IN; Sharp FR

Genomics. 2008 Jan;91(1):22-9. Epub 2007 Nov 14.

PubMed abstract

Regression in autism: prevalence and associated factors in the CHARGE Study

Author(s): Hansen RL; Ozonoff S; Krakowiak P; Angkustsiri K; Jones C; Deprey LJ; Le DN; Croen LA; Hertz-Picciotto I

Ambul Pediatr. 2008 Jan-Feb;8(1):25-31.

PubMed abstract

Meta-analysis of antioxidant intake and the risk of esophageal and gastric cardia adenocarcinoma

Author(s): Kubo A; Corley DA

Am J Gastroenterol. 2007 Oct;102(10):2323-30; quiz 2331. Epub 2007 Jun 20.

PubMed abstract

Maternal and paternal age and risk of autism spectrum disorders

Author(s): Croen LA; Najjar DV; Fireman B; Grether JK

Arch Pediatr Adolesc Med. 2007 Apr;161(4):334-40.

PubMed abstract

Infection in the first 2 years of life and autism spectrum disorders

Author(s): Rosen NJ; Yoshida CK; Croen LA

Pediatrics. 2007 Jan;119(1):e61-9.

PubMed abstract

The epidemiology of autism spectrum disorders

Author(s): Newschaffer CJ; Croen LA; Daniels J; Giarelli E; Grether JK; Levy SE; Mandell DS; Miller LA; Pinto-Martin J; Reaven J; Reynolds AM; Rice CE; Schendel D; Windham GC

Annu Rev Public Health. 2007;28:235-58.

PubMed abstract

A comparison of health care utilization and costs of children with and without autism spectrum disorders in a large group-model health plan

Author(s): Croen LA; Najjar DV; Ray GT; Lotspeich L; Bernal P

Pediatrics. 2006 Oct;118(4):e1203-11.

PubMed abstract

Attention-deficit/hyperactivity disorder in children: excess costs before and after initial diagnosis and treatment cost differences by ethnicity

Author(s): Ray GT; Levine P; Croen LA; Bokhari FA; Hu TW; Habel LA

Arch Pediatr Adolesc Med. 2006 Oct;160(10):1063-9.

PubMed abstract

Potential association between infertility and spinal neural tube defects in offspring

Author(s): Wu YW; Croen LA; Henning L; Najjar DV; Schembri M; Croughan MS

Birth Defects Res A Clin Mol Teratol. 2006 Oct;76(10):718-22.

PubMed abstract

Autism spectrum disorders in relation to distribution of hazardous air pollutants in the san francisco bay area

Author(s): Windham GC; Zhang L; Gunier R; Croen LA; Grether JK

Environ Health Perspect. 2006 Sep;114(9):1438-44.

PubMed abstract

Cerebral palsy in a term population: risk factors and neuroimaging findings

Author(s): Wu YW; Croen LA; Shah SJ; Newman TB; Najjar DV

Pediatrics. 2006 Aug;118(2):690-7.

PubMed abstract

The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism

Author(s): Hertz-Picciotto I; Croen LA; Hansen R; Jones CR; van de Water J; Pessah IN

Environ Health Perspect. 2006 Jul;114(7):1119-25.

PubMed abstract

Congenital anomalies associated with autism spectrum disorders

Author(s): Wier ML; Yoshida CK; Odouli R; Grether JK; Croen LA

Dev Med Child Neurol. 2006 Jun;48(6):500-7.

PubMed abstract

Predictors of outcome in perinatal arterial stroke: a population-based study

Author(s): Lee J; Croen LA; Lindan C; Nash KB; Yoshida CK; Ferriero DM; Barkovich AJ; Wu YW

Ann Neurol. 2005 Aug;58(2):303-8.

PubMed abstract

Trends in severe bronchopulmonary dysplasia rates between 1994 and 2002

Author(s): Smith VC; Zupancic JA; McCormick MC; Croen LA; Greene J; Escobar GJ; Richardson DK

J Pediatr. 2005 Apr;146(4):469-73.

PubMed abstract

Maternal and infant characteristics associated with perinatal arterial stroke in the infant

Author(s): Lee J; Croen LA; Backstrand KH; Yoshida CK; Henning LH; Lindan C; Ferriero DM; Fullerton HJ; Barkovich AJ; Wu YW

JAMA. 2005 Feb 9;293(6):723-9.

PubMed abstract

Neonatal hyperbilirubinemia and risk of autism spectrum disorders

Author(s): Croen LA; Yoshida CK; Odouli R; Newman TB

Pediatrics. 2005 Feb;115(2):e135-8.

PubMed abstract

Maternal autoimmune diseases, asthma and allergies, and childhood autism spectrum disorders: a case-control study

Author(s): Croen LA; Grether JK; Yoshida CK; Odouli R; Van de Water J

Arch Pediatr Adolesc Med. 2005 Feb;159(2):151-7.

PubMed abstract

Identifying environmental contributions to autism: provocative clues and false leads

Author(s): Lawler CP; Croen LA; Grether JK; van de Water J

Ment Retard Dev Disabil Res Rev. 2004;10(4):292-302.

PubMed abstract

Perinatal stroke in children with motor impairment: a population-based study

Author(s): Wu YW; March WM; Croen LA; Grether JK; Escobar GJ; Newman TB

Pediatrics. 2004 Sep;114(3):612-9.

PubMed abstract

Rehospitalization in the first year of life among infants with bronchopulmonary dysplasia

Author(s): Smith VC; Zupancic JA; McCormick MC; Croen LA; Greene J; Escobar GJ; Richardson DK

J Pediatr. 2004 Jun;144(6):799-803.

PubMed abstract

Chorioamnionitis and cerebral palsy in term and near-term infants

Author(s): Wu YW; Escobar GJ; Grether JK; Croen LA; Greene JD; Newman TB

JAMA. 2003 Nov 26;290(20):2677-84.

PubMed abstract

On the twin risk in autism

Author(s): Hallmayer J; Glasson EJ; Bower C; Petterson B; Croen L; Grether J; Risch N

Am J Hum Genet. 2002 Oct;71(4):941-6. Epub 2002 Sep 12.

PubMed abstract

The changing prevalence of autism in California

Author(s): Croen LA; Grether JK; Hoogstrate J; Selvin S

J Autism Dev Disord. 2002 Jun;32(3):207-15.

PubMed abstract

Descriptive epidemiology of autism in a California population: who is at risk?

Author(s): Croen LA; Grether JK; Selvin S

J Autism Dev Disord. 2002 Jun;32(3):217-24.

PubMed abstract

Apolipoprotein B and apolipoprotein E genotypes and sporadic holoprosencephaly

Author(s): Croen LA; Shaw GM; Barber RC; Baker MM; Finnell RH; Lammer EJ

Am J Med Genet. 2002 Feb 15;108(1):75-7.

PubMed abstract

Congenital abnormalities among children with cerebral palsy: More evidence for prenatal antecedents

Author(s): Croen LA; Grether JK; Curry CJ; Nelson KB

J Pediatr. 2001 Jun;138(6):804-10.

PubMed abstract

The epidemiology of mental retardation of unknown cause

Author(s): Croen LA; Grether JK; Selvin S

Pediatrics. 2001 Jun;107(6):E86.

PubMed abstract

Neuropeptides and neurotrophins in neonatal blood of children with autism or mental retardation

Author(s): Nelson KB; Grether JK; Croen LA; Dambrosia JM; Dickens BF; Jelliffe LL; Hansen RL; Phillips TM

Ann Neurol. 2001 May;49(5):597-606.

PubMed abstract

Maternal exposure to nitrate from drinking water and diet and risk for neural tube defects

Author(s): Croen LA; Todoroff K; Shaw GM

Am J Epidemiol. 2001 Feb 15;153(4):325-31.

PubMed abstract