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Bruce Fireman is a biostatistician and research scientist at the Division of Research, Kaiser Permanente Northern California. His research interests include assessment of the effectiveness and safety of vaccines and drugs, and the costs and outcomes of healthcare delivery systems. He works with population-based data, comparing the effectiveness of alternative treatments and alternative ways of delivering healthcare. He has evaluated disease management programs, Web-based care and primary care teams. He has collaborated with Kaiser Permanente clinicians and administrators in efforts to improve health services.

Current Positions

  • Biostatistician III, Division of Research, Kaiser Permanente Northern California

Section Affiliations

Primary Research Interests

  • Outcomes of medical care
  • Vaccine safety and effectiveness
  • Costs of care
  • Survival analysis
  • Sequential analysis
  • Exact statistics, permutation tests

Publications

SARS-CoV-2 Vaccination Before and During Pregnancy and Prevention of Infant COVID-19 Infection

Authors: Jacobson KB;Merchant M;Fireman B;Klein NP;Zerbo O

Pediatrics. 2026 May 01;157(5).

PubMed abstract

Adjuvanted vs High-Dose Influenza Vaccines in Older US Adults: A Cluster Randomized Crossover Study

Authors: Hsiao A;Leong T;Fireman B;Hansen J;Zerbo O;Jacobson KB;Liao LD;Haag MDM;McGovern I;Zhang B;Dang J;Klein NP

JAMA Netw Open. 2026 May 01;9(5):e2610120. Epub 2026-05-01.

PubMed abstract

Respiratory syncytial virus (RSV) vaccine effectiveness against RSV-associated hospitalisations and emergency department encounters among adults aged 60 years and older in the USA, October, 2023, to March, 2024: a test-negative design analysis

Authors: Payne, Amanda B;Klein, Nicola P;Fireman, Bruce;Zerbo, Ousseny;Timbol, Julius;Goddard, Kristin S;Link-Gelles, Ruth; et al.

Respiratory syncytial virus (RSV) vaccine effectiveness against RSV-associated hospitalisations and emergency department encounters among adults aged 60 years and older in the USA, October, 2023, to March, 2024: a test-negative design analysis Authors: Payne, Amanda B; Watts, Janet A; Mitchell, Patrick K; Dascomb, Kristin; Irving, Stephanie A; Klein, Nicola P; Grannis, Shaun J; Ong, Toan C; Ball, Sarah W; DeSilva, Malini B; Natarajan, Karthik; Sheffield, Tamara; Bride, Daniel; Arndorfer, Julie; Naleway, Allison L; Koppolu, Padma; Fireman, Bruce; Zerbo, Ousseny; Timbol, Julius; Goddard, Kristin; Dixon, Brian E; Fadel, William F; Rogerson, Colin; Allen, Katie S; Rao, Suchitra; Mayer, David; Barron, Michelle; Reese, Sarah E; Rowley, Elizabeth A K; Najdowski, Morgan; Ciesla, Allison Avrich; Mak, Josephine; Reeves, Emily L; Akinsete, Omobosola O; McEvoy, Charlene E; Essien, Inih J; Tenforde, Mark W; Fleming-Dutra, Katherine E; Link-Gelles, Ruth Lancet. 2024 Oct 19;404(10462):1547-1559.

PubMed abstract

Incidence and Risk of Coronavirus Disease 2019 Hospitalization Among Unvaccinated Children

Authors: Zerbo, Ousseny;Timbol, Julius;Hansen, John R;Goddard, Kristin;Layefsky, Evan;Ross, Pat;Fireman, Bruce;Nguyen, Dao;Greenhow, Tara L;Klein, Nicola P

Incidence and Risk of Coronavirus Disease 2019 Hospitalization Among Unvaccinated Children Authors: Zerbo, Ousseny; Timbol, Julius; Hansen, John R; Goddard, Kristin; Layefsky, Evan; Ross, Pat; Fireman, Bruce; Nguyen, Dao; Greenhow, Tara L; Klein, Nicola P Influenza Other Respir Viruses. 2024 Oct;18(10):e70022.

PubMed abstract

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