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Monique M. Hedderson, PhD

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Kaiser Permanente Division of Research
2000 Broadway
Oakland, CA 94612

(510) 891-3580 (phone)
Monique.m.hedderson@kp.org
Kaiser Permanente Researcher Profiles


Monique Hedderson, PhD, is a research scientist at the Kaiser Permanente Northern California Division of Research. She received her Master's in public health from the University of Washington in 2000 and her PhD in epidemiology from the University of Washington in 2005. Dr. Hedderson’s research interests lie principally, but not exclusively, in the field of maternal and child health. Her research portfolio investigates the influence of preconception, prenatal and early childhood exposures on maternal and child health. Specifically, she has sought to understand how potentially modifiable factors before and during early pregnancy contribute to the risk of metabolic complications in women during pregnancy and postpartum, as well as their children. Dr. Hedderson has a long-standing interest in developing innovative targeted prevention and treatment strategies for high risk populations, especially interventions among reproductive aged women that can be implemented into clinical practice. She is also interested in the pharmacogenetics of glycemic response to metformin among patients with type 2 diabetes. This area of research has the potential to inform data-driven prescribing and precision medicine for antidiabetic drug therapy.

Current Position(s):

  • Research Scientist III, Division of Research, Kaiser Permanente Northern California

Section Affiliations:

Primary Research Interests:

  • Reproductive and perinatal epidemiology
  • Gestational diabetes
  • In utero behavioral and environmental exposures related to maternal and child health

    Can hydroxychloroquine prevent preeclampsia and preterm delivery in lupus pregnancy?

    Pregnant women with lupus are at high risk to develop preeclampsia and preterm delivery. This work leverages three large population-based databases with detailed prescription and clinical data to determine whether use of hydroxychloroquine during pregnancy among women with lupus reduces the risk of preeclampsia and preterm delivery disentangling these outcomes from the effects of potential mediators. This study will provide key information on hydroxychloroquine use and prescription practices to improve the analytic paradigm and inform our clinical understanding hydroxychloroquine use in lupus pregnancy.
    Investigator: Hedderson, Monique
    Funder: National Institute of Arthritis and Musculoskeletal and Skin Diseases

    The Study of Women's Health Across the Nation (SWAN)

    SWAN VI aims to elucidate menopause transition characteristics and trajectories of midlife health markers (inflammation, metabolic and cardiovascular risk factors, body composition, and bone, genitourinary, and vascular health) that are related to the preservation of physical and cognitive functioning, avoidance or delay of adverse health outcomes, and enhancement of social and psychological well-being, all of which will optimize successful aging.
    Investigator: Hedderson, Monique
    Funder: National Institute on Aging

    Understanding racial-ethnic disparities in preterm birth sub-types and prenatal care utilization

    The study will examine racial-ethnic disparities in the risk of preterm birth overall and by preterm birth sub-types. It will also study whether the racial-ethnic disparities in preterm births and preterm birth sub-types are modified by the level of prenatal care received.
    Investigator: Hedderson, Monique
    Funder: Northern California Community Benefit Programs

    Cluster-randomized Trial of a Mobile Health Intervention to Achieve Appropriate Gestational Weight Gain in Overweight and Obese Women

    This randomized trial will test whether the implementation of an mHealth tool in the health-plan setting increases the proportion of overweight and obese women with appropriate total gestational weight gain, according to Institute of Medicine (IOM) guidelines in comparison to usual care. Primary outcomes include the proportion of women with total gestational weight gain meeting the IOM guidelines and the rate of gain from the first trimester to delivery (in kilograms per week).
    Investigator: Hedderson, Monique
    Funder: National Institute of Diabetes and Digestive and Kidney Diseases

    Atopic Dermatitis Standing Cohort Using a Cohort of Kaiser Permanente Northern California Members

    A cohort study of Kaiser Permanente Northern California patients with moderate-to-severe atopic dermatitis (AD) will be used to estimate baseline characteristics and background incidence rates of safety events. Data from this study will provide valuable information regarding the current incidence rates of adverse outcomes among patients with AD. Safety events of interest include: viral reactivation, malignancies, lymphoproliferative disorders, thrombocytopenia, major/minor bleeding events, major adverse cardiovascular events, alterations in lipid profiles, and thromboembolism.
    Investigator: Hedderson, Monique
    Funder: Pfizer Inc.

    Development and Testing of a Mobile-Health (m-health) Intervention tool to Help Obese Women Achieve Appropriate Gestational Weight Gain

    To determine whether a mobile-health (m-health) tool (accessible via smartphone or website) intervention for obese pregnant improves patient satisfaction with their gestational weight gain, quality of life, stress and depression during pregnancy. Provider satisfaction with discussing gestational weight gain among their patients who used the m-health tool will also be assessed.
    Investigator: Hedderson, Monique
    Funder: The Permanente Medical Group

    Glyburide Versus Insulin for the Treatment of Women with Gestational Diabetes in Kaiser Permanente Northern California

    We aim to compare the effectiveness and safety of glyburide and insulin at improving neonatal and maternal outcomes among women with gestational diabetes mellitus (GDM) requiring medication therapy in Kaiser Permanente Northern California from 2007 to 2016. We will use a cohort study design including women with GDM diagnosed from 2007 to 2016 where treatment groups contrasted are defined by therapy regimens (i.e., insulin versus glyburide or early versus late initiation of glyburide). This project will overcome shortcomings of past studies conducted in this area by using modern statistical methods that allow us to take advantage of variation in treatment patterns after the implementation of the universal Perinatal Center referral policy in 2007. More specifically, our approach consists of a cohort study with time-varying exposure to insulin and glyburide during pregnancy.
    Investigator: Hedderson, Monique
    Funder: 

    Iodinated Contrast Agents and Risk of Hypothyroidism in Young Children in the United States

    This study will estimate the incidence of pulmonary hypothyroid in a pediatric population of children under age 4, based on data from the US-based Kaiser Permanente Northern California database, who were exposed to iodinated contrast agent through having a diagnostic procedure.
    Investigator: Hedderson, Monique
    Funder: Bayer AG

    Pregravid Biomarkers and Risk of Gestational Diabetes Mellitus Risk, Fetal Growth and Progression to Diabetes

    This study will examine pregravid biomarkers of metabolic risk (adiponectin, high molecular weight adiponectin, c-reactive protein, liver enzymes, fetuin-A and LDL particle size) in relation to risk of gestational diabetes mellitus among women who participated in the Kaiser Permanente Northern California (KPNC) multiphasic health check-up (1985-1996) and had a subsequent pregnancy in KPNC.
    Investigator: Hedderson, Monique
    Funder: National Institute of Child Health and Human Development

    Discovery of Pharmacogenomic Biomarkers for Metformin Response

    The primary goal of this multi-site study is to identify genetic variants that impact response to metformin in patients with diabetes from multiple ethnic groups in the U.S. and Europe
    Investigator: Hedderson, Monique
    Funder: National Institute of General Medical Sciences

    Pharmacogenomics Study of Extreme Response to Metformin

    In this collaboration with GlaxoSmithKline, University of California San Francisco and Kaiser Permanente Northern California, we propose to perform a genome-wide association study in 1,000 patients of European ancestry with extreme response phenotypes to metformin using genomewide array and human exome chip, which include rare nonsynonymous variants. Our aim is to determine whether rare variants, either acting alone or in combination, explain much of the variation in response to metformin, particularly in the extreme responder and non-responder groups.
    Investigator: Hedderson, Monique
    Funder: GlaxoSmithKline PLC
    No results found matching criteria

    Efficacious lifestyle interventions for appropriate gestational weight gain in women with overweight or obesity set in the health care system: a scoping review

    Author(s): Barroso, Cristina S; Yockey, Andrew; Degon, Emoni; Gautam Poudel, Pragya; Brown, Susan D; Hedderson, Monique M; Moreno-Hunt, Carey; Ehrlich, Samantha F

    J Matern Fetal Neonatal Med. 2022 Dec;35(25):6411-6424. Epub 2021-05-25.

    PubMed abstract

    Urinary Phenols in Early to Mid-Pregnancy and Risk of Gestational Diabetes: A Longitudinal Study in a Multiracial Cohort

    Author(s): Zhu, Yeyi; Hedderson, Monique M; Calafat, Antonia M; Alexeeff, Stacey E; Feng, Juanran; Quesenberry, Charles P; Ferrara, Assiamira

    Diabetes. 2022 Dec 01;71(12):2539-2551.

    PubMed abstract

    Changes in 24-Hour Movement Behaviors From Early to Late Pregnancy in Individuals With Prepregnancy Overweight or Obesity

    Author(s): Badon, Sylvia E; Ferrara, Assiamira; Gabriel, Kelley Pettee; Avalos, Lyndsay A; Hedderson, Monique M

    J Phys Act Health. 2022 Dec 01;19(12):842-846. Epub 2022-11-12.

    PubMed abstract

    Fibroids and vitamin D: another piece of the puzzle

    Author(s): Mitro, Susanna D; Waetjen, L Elaine; Hedderson, Monique M

    Fertil Steril. 2022 Dec;118(6):1137-1138. Epub 2022-11-04.

    PubMed abstract

    Association of serum folate levels during pregnancy and prenatal depression

    Author(s): Avalos, Lyndsay A; Nance, Nerissa; Caan, Bette; Sujan, Ayesha C; Uriu-Adams, Janet Y; Li, De-Kun; Quesenberry, Charles P; Hedderson, Monique M

    J Matern Fetal Neonatal Med. 2022 Nov 17:1-4.

    PubMed abstract

    Reconciling Between Medication Orders and Medication Fills for Lupus in Pregnancy

    Author(s): Simard, Julia F; Liu, Emily F; Chakravarty, Eliza; Rector, Amadeia; Cantu, Miranda; Kuo, Daniel Z; Shaw, Gary M; Druzin, Maurice; Weisman, Michael H; Hedderson, Monique M

    ACR Open Rheumatol. 2022 Oct 17.

    PubMed abstract

    Gestational diabetes mellitus, prenatal maternal depression, and risk for postpartum depression: an Environmental influences on Child Health Outcomes (ECHO) Study

    Author(s): Shuffrey, Lauren C; Jacobson, Melanie; Crum, Rosa M; program collaborators for Environmental influences on Child Health Outcomes,; et al.

    BMC Pregnancy Childbirth. 2022 Oct 08;22(1):758. Epub 2022-10-08.

    PubMed abstract

    Impact of the COVID-19 pandemic on children's sleep habits: an ECHO study

    Author(s): Lucchini, Maristella; Friedman, Chloe; Hockett, Christine W; Environmental influences on Child Health Outcomes,; et al.

    Pediatr Res. 2022 Oct 04.

    PubMed abstract

    Accuracy of diagnostic codes for prenatal opioid exposure and neonatal opioid withdrawal syndrome

    Author(s): Kuzniewicz, Michael W; Campbell, Cynthia I; Li, Sherian; Walsh, Eileen M; Croen, Lisa A; Comer, Sandra D; Pimentel, Samuel D; Hedderson, Monique; Sun, Lena S

    J Perinatol. 2022 Sep 21.

    PubMed abstract

    Changes in BMI During the COVID-19 Pandemic

    Author(s): Knapp, Emily A; Hedderson, Monique; Bekelman, Traci A; Chandran, Aruna; et al.

    Pediatrics. 2022 09 01;150(3).

    PubMed abstract

    Health Behavior Changes during the COVID-19 Pandemic: A Longitudinal Analysis among Children

    Author(s): Bekelman, Traci A; Friesen, Kaylyn; Hockett, Christine W; Program Collaborators for Environmental influences on Child Health Outcomes (ECHO),; et al.

    Int J Environ Res Public Health. 2022 Jul 28;19(15). Epub 2022-07-28.

    PubMed abstract

    Sociodemographic Variation in Children's Health Behaviors During the COVID-19 Pandemic

    Author(s): Bekelman, Traci A; Fry, Rebecca C; Hipwell, Alison E; program collaborators for Environmental influences on Child Health Outcomes (ECHO),; et al.

    Child Obes. 2022 Jul 19.

    PubMed abstract

    Reach, acceptability, and perceived success of a telehealth diabetes prevention program among racially and ethnically diverse patients with gestational diabetes: the GEM cluster-randomized trial

    Author(s): Brown, Susan D; Hedderson, Monique M; Gordon, Nancy; Albright, Cheryl L; Tsai, Ai-Lin; Quesenberry, Charles P; Ferrara, Assiamira

    Transl Behav Med. 2022 Jul 18;12(7):793-799.

    PubMed abstract

    Coping strategies for COVID-19 pandemic-related stress and mental health during pregnancy

    Author(s): Badon, Sylvia E; Croen, Lisa A; Ferrara, Assiamira; Ames, Jennifer L; Hedderson, Monique M; Young-Wolff, Kelly C; Zhu, Yeyi; Avalos, Lyndsay A

    J Affect Disord. 2022 Jul 15;309:309-313. Epub 2022-04-28.

    PubMed abstract

    Impaired fasting glucose in pregnancy: improved perinatal outcomes with active glycemic management

    Author(s): Berglin, Mendy; Anderson, Meredith; Ritterman Weintraub, Miranda; Navalta, Stephanie; Hedderson, Monique; Ferrara, Assiamira; Greenberg, Mara

    Am J Perinatol. 2022 Jun 24.

    PubMed abstract

    A Web-Based mHealth Intervention With Telephone Support to Increase Physical Activity Among Pregnant Patients With Overweight or Obesity: Feasibility Randomized Controlled Trial

    Author(s): Thomas, Tainayah; Xu, Fei; Sridhar, Sneha; Sedgwick, Tali; Nkemere, Linda; Badon, Sylvia E; Quesenberry, Charles; Ferrara, Assiamira; Mandel, Sarah; Brown, Susan D; Hedderson, Monique

    JMIR Form Res. 2022 Jun 22;6(6):e33929. Epub 2022-06-22.

    PubMed abstract

    Uptake of guideline-recommended postpartum diabetes screening among diverse women with gestational diabetes: associations with patient factors in an integrated health system in USA

    Author(s): Brown, Susan D; Hedderson, Monique M; Zhu, Yeyi; Tsai, Ai-Lin; Feng, Juanran; Quesenberry, Charles P; Ferrara, Assiamira

    BMJ Open Diabetes Res Care. 2022 06;10(3).

    PubMed abstract

    Perinatal Complications in Individuals in California With or Without SARS-CoV-2 Infection During Pregnancy

    Author(s): Ferrara, Assiamira; Hedderson, Monique M; Zhu, Yeyi; Avalos, Lyndsay A; Kuzniewicz, Michael W; Myers, Laura C; Ngo, Amanda L; Gunderson, Erica P; Ritchie, Jenna L; Quesenberry, Charles P; Greenberg, Mara

    JAMA Intern Med. 2022 05 01;182(5):503-512.

    PubMed abstract

    Contribution of Maternal Cardiometabolic Risk Factors to Racial-Ethnicity Disparities in Preterm Birth Subtypes

    Author(s): Hedderson, Monique M; Xu, Fei; Dayo, Olumayowa M; Liu, Emily; Sridhar, Sneha; Lee, Catherine; Greenberg, Mara

    Am J Obstet Gynecol MFM. 2022 05;4(3):100608. Epub 2022-03-04.

    PubMed abstract

    Association of Glyburide and Subcutaneous Insulin With Perinatal Complications Among Women With Gestational Diabetes

    Author(s): Hedderson, Monique M; Badon, Sylvia E; Pimentel, Noel; Xu, Fei; Regenstein, Anne; Ferrara, Assiamira; Neugebauer, Romain

    JAMA Netw Open. 2022 03 01;5(3):e225026. Epub 2022-03-01.

    PubMed abstract

    Contributions of COVID-19 Pandemic-Related Stressors to Racial and Ethnic Disparities in Mental Health During Pregnancy

    Author(s): Avalos, Lyndsay A; Nance, Nerissa; Zhu, Yeyi; Croen, Lisa A; Young-Wolff, Kelly C; Zerbo, Ousseny; Hedderson, Monique M; Ferrara, Assiamira; Ames, Jennifer L; Badon, Sylvia E

    Front Psychiatry. 2022;13:837659. Epub 2022-03-14.

    PubMed abstract

    Associations of COVID-19-Related Health, Healthcare and Economic Factors With Prenatal Depression and Anxiety

    Author(s): Avalos, Lyndsay A; Nance, Nerissa; Badon, Sylvia E; Young-Wolff, Kelly; Ames, Jennifer; Zhu, Yeyi; Hedderson, Monique M; Ferrara, Assiamira; Zerbo, Ousseny; Greenberg, Mara; Croen, Lisa A

    Int J Public Health. 2022;67:1604433. Epub 2022-05-04.

    PubMed abstract

    Rates of cardiovascular events among patients with moderate-to-severe atopic dermatitis in an integrated health care system: A retrospective cohort study

    Author(s): Hedderson, Monique M; Asgari, Maryam M; Xu, Fei; Quesenberry, Charles P; Sridhar, Sneha; Geier, Jamie; Lemeshow, Adina R

    PLoS One. 2022;17(11):e0277469. Epub 2022-11-17.

    PubMed abstract

    Disparities in Risks of Inadequate and Excessive Intake of Micronutrients during Pregnancy

    Author(s): Sauder, Katherine A; Avalos, Lyndsay A; Zhu, Yeyi; Breton, Carrie V; Program Collaborators for Environmental influences on Child Health Outcomes (ECHO),; et al.

    J Nutr. 2021 11 02;151(11):3555-3569.

    PubMed abstract

    Methods-Motivational Interviewing Approach for Enhanced Retention and Attendance

    Author(s): Jake-Schoffman, Danielle E; Baiocchi, Michael; Galarce, Maren N; Moran, Patricia J; Kiernan, Michaela; et al.

    Am J Prev Med. 2021 10;61(4):606-617.

    PubMed abstract

    Lifestyle-related education and counseling resource utilization and cardiovascular biomarkers in midlife women with low physical activity

    Author(s): Badon, Sylvia E; Nance, Nerissa; Fogelberg, Renee; Quesenberry, Charles; Hedderson, Monique M; Avalos, Lyndsay A

    Prev Med Rep. 2021 Sep;23:101401. Epub 2021-05-17.

    PubMed abstract

    Healthy preconception and early-pregnancy lifestyle and risk of preterm birth: a prospective cohort study

    Author(s): Zhu, Yeyi; Hedderson, Monique M; Brown, Susan D; Badon, Sylvia E; Feng, Juanran; Quesenberry, Charles P; Ferrara, Assiamira

    Am J Clin Nutr. 2021 08 02;114(2):813-821.

    PubMed abstract

    Mediating Effects of Cardiometabolic Risk Factors on the Association Between Maternal Race-Ethnicity and Cesarean Delivery Among Low-Risk Women

    Author(s): Hedderson, Monique M; Xu, Fei; Liu, Emily; Sridhar, Sneha B; Quesenberry, Charles P; Flanagan, Tracy A

    J Womens Health (Larchmt). 2021 07;30(7):1028-1037. Epub 2021-02-11.

    PubMed abstract

    Dual trajectories of physical activity and blood lipids in midlife women: The Study of Women's Health Across the Nation

    Author(s): Badon, Sylvia E; Gabriel, Kelley Pettee; Karvonen-Gutierrez, Carrie; Sternfeld, Barbara; Gold, Ellen B; Waetjen, L Elaine; Lee, Catherine; Avalos, Lyndsay A; El Khoudary, Samar R; Hedderson, Monique M

    Maturitas. 2021 Apr;146:49-56. Epub 2021-02-06.

    PubMed abstract

    Gestational weight gain and adverse pregnancy outcomes by pre-pregnancy BMI category in women with chronic hypertension: A cohort study

    Author(s): Badon, Sylvia E; Dublin, Sascha; Nance, Nerissa; Hedderson, Monique M; Neugebauer, Romain; Easterling, Thomas; Cheetham, T Craig; Chen, Lu; Holt, Victoria L; Avalos, Lyndsay A

    Pregnancy Hypertens. 2021 Mar;23:27-33. Epub 2020-10-24.

    PubMed abstract

    Exercise During the First Trimester of Pregnancy and the Risks of Abnormal Screening and Gestational Diabetes Mellitus

    Author(s): Ehrlich, Samantha F; Ferrara, Assiamira; Hedderson, Monique M; Feng, Juanran; Neugebauer, Romain

    Diabetes Care. 2021 02;44(2):425-432. Epub 2020-12-21.

    PubMed abstract

    Racial and geographic variation in effects of maternal education and neighborhood-level measures of socioeconomic status on gestational age at birth: Findings from the ECHO cohorts

    Author(s): Dunlop, Anne L; Breton, Carrie; Thepaksorn, Elizabeth Hom; program collaborators for Environmental Influences on Child Health Outcomes,; et al.

    PLoS One. 2021;16(1):e0245064. Epub 2021-01-08.

    PubMed abstract

    COVID-19 prevalence, symptoms, and sociodemographic disparities in infection among insured pregnant women in Northern California

    Author(s): Ames, Jennifer L; Avalos, Lyndsay A; Badon, Sylvia E; Greenberg, Mara B; Hedderson, Monique M; Kuzniewicz, Michael W; Qian, Yinge; Zerbo, Ousseny; Zhu, Yeyi; Croen, Lisa A; Croen, Lisa A; et al.

    PLoS One. 2021;16(9):e0256891. Epub 2021-09-03.

    PubMed abstract

    Development and Validation of an Obstetric Comorbidity Risk Score for Clinical Use

    Author(s): Ruppel, Halley; Liu, Vincent X; Kipnis, Patricia; Hedderson, Monique M; Greenberg, Mara; Forquer, Heather; Lawson, Brian; Escobar, Gabriel J

    Womens Health Rep (New Rochelle). 2021;2(1):507-515. Epub 2021-11-02.

    PubMed abstract

    Impact of nulliparity, hypertensive disorders of pregnancy, and gestational diabetes on vasomotor symptoms in midlife women

    Author(s): Cortés, Yamnia I; Conant, Rhoda; Catov, Janet M; Matthews, Karen A; Crawford, Sybil L; Hedderson, Monique M; Thurston, Rebecca C

    Menopause. 2020 12;27(12):1363-1370.

    PubMed abstract

    Gestational weight gain, birthweight and early-childhood obesity: between- and within-family comparisons

    Author(s): Badon, Sylvia E; Quesenberry, Charles P; Xu, Fei; Avalos, Lyndsay A; Hedderson, Monique M

    Int J Epidemiol. 2020 10 01;49(5):1682-1690.

    PubMed abstract

    Study protocol: Using peer support to aid in prevention and treatment in prediabetes (UPSTART)

    Author(s): Heisler M; Hedderson M; Kim E; Schmittdiel JA; et al.

    Contemp Clin Trials. 2020 08;95:106048. Epub 2020-06-01.

    PubMed abstract

    Prenatal Depression and Diet Quality During Pregnancy

    Author(s): Avalos LA; Caan B; Nance N; Zhu Y; Li DK; Quesenberry C; Hyde RJ; Hedderson MM

    J Acad Nutr Diet. 2020 06;120(6):972-984. Epub 2020-02-13.

    PubMed abstract

    A telehealth lifestyle intervention to reduce excess gestational weight gain in pregnant women with overweight or obesity (GLOW): a randomised, parallel-group, controlled trial

    Author(s): Ferrara A; Hedderson MM; Brown SD; Ehrlich SF; Tsai AL; Feng J; Galarce M; Marcovina S; Catalano P; Quesenberry CP

    Lancet Diabetes Endocrinol. 2020 06;8(6):490-500.

    PubMed abstract

    Alternative Wear-time Estimation Methods Compared to Traditional Diary Logs for Wrist-Worn ActiGraph Accelerometers in Pregnant Women

    Author(s): Ehrlich, Samantha F; Casteel, Amanda J; Crouter, Scott E; Hibbing, Paul R; Hedderson, Monique M; Brown, Susan D; Galarce, Maren; Coe, Dawn P; Bassett, David R; Ferrara, Assiamira

    J Meas Phys Behav. 2020 Jun;3(2):110-117.

    PubMed abstract

    Understanding childhood obesity in the US: the NIH environmental influences on child health outcomes (ECHO) program

    Author(s): Tylavsky FA; Catellier DJ; Zhu Y; Polk S; Trasande L; et al.

    Int J Obes (Lond). 2020 03;44(3):617-627. Epub 2019-10-24.

    PubMed abstract

    Exercise During the First Trimester and Infant Size at Birth: Targeted Maximum Likelihood Estimation of the Causal Risk Difference

    Author(s): Ehrlich SF; Neugebauer RS; Feng J; Hedderson MM; Ferrara A

    Am J Epidemiol. 2020 02 28;189(2):133-145.

    PubMed abstract

    Pre- and Early Pregnancy Onset Depression and Subsequent Rate of Gestational Weight Gain

    Author(s): Badon SE; Hedderson MM; Hyde RJ; Quesenberry CP; Avalos LA

    J Womens Health (Larchmt). 2019 09;28(9):1237-1245. Epub 2019-05-07.

    PubMed abstract

    Prenatal Opioid Exposure: Neurodevelopmental Consequences and Future Research Priorities

    Author(s): Conradt E; Croen LA; Hedderson MM; Lester BM; et al.

    Pediatrics. 2019 Sep;144(3).

    PubMed abstract

    Enhanced Recovery After Surgery to Change Process Measures and Reduce Opioid Use After Cesarean Delivery: A Quality Improvement Initiative

    Author(s): Hedderson M; Quesenberry C; Reyes V; Liu V; et al.

    Obstet Gynecol. 2019 09;134(3):511-519.

    PubMed abstract

    Iodinated Contrast Agents and Risk of Hypothyroidism in Young Children in the United States

    Author(s): Jick SS; Hedderson M; Xu F; Cheng Y; Palkowitsch P; Michel A

    Issues Ment Health Nurs. 2019 Nov;40(11):988-989. Epub 2019-08-05.

    PubMed abstract

    Gestational weight gain and optimal wellness (GLOW): rationale and methods for a randomized controlled trial of a lifestyle intervention among pregnant women with overweight or obesity

    Author(s): Brown SD; Hedderson MM; Ehrlich SF; Galarce MN; Tsai AL; Quesenberry CP; Ferrara A

    BMC Pregnancy Childbirth. 2019 Apr 30;19(1):145. Epub 2019-04-30.

    PubMed abstract

    Poor diet quality in pregnancy is associated with increased risk of excess fetal growth: a prospective multi-racial/ethnic cohort study

    Author(s): Zhu Y; Hedderson MM; Sridhar S; Xu F; Feng J; Ferrara A

    Int J Gynaecol Obstet. 2020 Jan;148 Suppl 1:42-58.

    PubMed abstract

    Dietary Quality and Glycemic Control Among Women with Gestational Diabetes Mellitus

    Author(s): Gadgil MD; Ehrlich SF; Zhu Y; Brown SD; Hedderson MM; Crites Y; Ferrara A

    J Womens Health (Larchmt). 2019 02;28(2):178-184. Epub 2018-10-30.

    PubMed abstract

    Diagnostic thresholds for pregnancy hyperglycemia, maternal weight status and the risk of childhood obesity in a diverse Northern California cohort using health care delivery system data

    Author(s): Ehrlich SF; Hedderson MM; Xu F; Ferrara A

    PLoS One. 2019;14(5):e0216897. Epub 2019-05-10.

    PubMed abstract

    Central Obesity Increases the Risk of Gestational Diabetes Partially Through Increasing Insulin Resistance

    Author(s): Zhu Y; Hedderson MM; Quesenberry CP; Feng J; Ferrara A

    Obesity (Silver Spring). 2018 Nov 21.

    PubMed abstract

    A Pre-Pregnancy Biomarker Risk Score Improves Prediction of Future Gestational Diabetes

    Author(s): Badon SE; Zhu Y; Sridhar SB; Xu F; Lee C; Ehrlich SF; Quesenberry CP; Hedderson MM

    J Endocr Soc. 2018 Oct 01;2(10):1158-1169. Epub 2018-09-13.

    PubMed abstract

    A Tailored Letter Based on Electronic Health Record Data Improves Gestational Weight Gain Among Women With Gestational Diabetes: The Gestational Diabetes' Effects on Moms (GEM) Cluster-Randomized Controlled Trial

    Author(s): Hedderson MM; Brown SD; Ehrlich SF; Tsai AL; Zhu Y; Quesenberry CP; Crites Y; Ferrara A

    Diabetes Care. 2018 07;41(7):1370-1377. Epub 2018-04-18.

    PubMed abstract

    Genetic Variants in CPA6 and PRPF31 are Associated with Variation in Response to Metformin in Individuals with Type 2 Diabetes

    Author(s): Rotroff DM; Kubo M; ACCORD/ACCORDion Investigators; et al.

    Diabetes. 2018 07;67(7):1428-1440. Epub 2018-04-12.

    PubMed abstract

    A cohort study of maternal cardiometabolic risk factors and primary cesarean delivery in an integrated health system

    Author(s): Hedderson MM; Xu F; Sridhar SB; Han ES; Quesenberry CP; Crites Y

    PLoS ONE. 2018;13(7):e0199932. Epub 2018-07-03.

    PubMed abstract

    Liver Enzymes in Early to Mid-pregnancy, Insulin Resistance, and Gestational Diabetes Risk: A Longitudinal Analysis

    Author(s): Zhu Y; Hedderson MM; Quesenberry CP; Feng J; Ferrara A

    Front Endocrinol (Lausanne). 2018;9:581. Epub 2018-10-02.

    PubMed abstract

    Variants in Pharmacokinetic Transporters and Glycaemic Response to Metformin: A MetGen Meta-Analysis

    Author(s): Dujic T; van der Heijden AA; Pearson ER; et al.

    Clin Pharmacol Ther. 2017 Jun;101(6):763-772. Epub 2017-02-03.

    PubMed abstract

    The Pregnancy Environment and Lifestyle Study (PETALS): a population-based longitudinal multi-racial birth cohort

    Author(s): Zhu Y; Hedderson MM; Feng J; Mevi AA; Ferrara A

    BMC Pregnancy Childbirth. 2017 04 17;17(1):122. Epub 2017-04-17.

    PubMed abstract

    Moderate intensity sports and exercise is associated with glycaemic control in women with gestational diabetes

    Author(s): Ehrlich SF; Hedderson MM; Brown SD; Sternfeld B; Chasan-Taber L; Feng J; Adams J; Ching J; Crites Y; Quesenberry CP; Ferrara A

    Diabetes Metab. 2017 Feb 23.

    PubMed abstract

    Trends and racial and ethnic disparities in the prevalence of pregestational type 1 and type 2 diabetes in Northern California: 1996-2014

    Author(s): Peng TY; Ehrlich SF; Crites Y; Kitzmiller JL; Kuzniewicz MW; Hedderson MM; Ferrara A

    Am J Obstet Gynecol. 2017 Feb;216(2):177.e1-177.e8. Epub 2016-10-15.

    PubMed abstract

    Perceived psychosocial stress and gestational weight gain among women with gestational diabetes

    Author(s): Kubo A; Ferrara A; Brown SD; Ehrlich SF; Tsai AL; Quesenberry CP; Crites Y; Hedderson MM

    PLoS ONE. 2017;12(3):e0174290. Epub 2017-03-28.

    PubMed abstract

    The Kaiser Permanente Northern California research program on genes, environment, and health (RPGEH) pregnancy cohort: study design, methodology and baseline characteristics

    Author(s): Hedderson MM; Avalos LA; Van den Eeden SK; Gunderson EP; Li DK; Altschuler A; Croen LA; Croen LA; et al.

    BMC Pregnancy Childbirth. 2016 Nov 29;16(1):381. Epub 2016-11-29.

    PubMed abstract

    A Longitudinal HbA1c Model Elucidates Genes Linked to Disease Progression on Metformin

    Author(s): Goswami S; Giacomini KM; Savic RM; et al.

    Clin Pharmacol Ther. 2016 Nov;100(5):537-547. Epub 2016-09-23.

    PubMed abstract

    Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin

    Author(s): Zhou K; Palmer CNA; Pearson ER; et al.

    Nat Genet. 2016 Sep;48(9):1055-1059. Epub 2016-08-08.

    PubMed abstract

    Lifestyle behaviors and ethnic identity among diverse women at high risk for type 2 diabetes

    Author(s): Brown SD; Ehrlich SF; Kubo A; Tsai AL; Hedderson MM; Quesenberry CP; Ferrara A

    Soc Sci Med. 2016 07;160:87-93. Epub 2016-05-14.

    PubMed abstract

    Pre-pregnancy adverse lipid profile and subsequent risk of gestational diabetes

    Author(s): Han ES; Krauss RM; Xu F; Sridhar SB; Ferrara A; Quesenberry CP; Hedderson MM

    J Clin Endocrinol Metab. 2016 Jul;101(7):2721-7. Epub 2016-04-05.

    PubMed abstract

    Validity of Self-Reported Pre-Pregnancy Weight and Body Mass Index Classification in an Integrated Health Care Delivery System

    Author(s): Han E; Abrams B; Sridhar S; Xu F; Hedderson M

    Paediatr Perinat Epidemiol. 2016 07;30(4):314-9. Epub 2016-03-09.

    PubMed abstract

    Moderate and Vigorous Intensity Exercise During Pregnancy and Gestational Weight Gain in Women with Gestational Diabetes

    Author(s): Ehrlich SF; Sternfeld B; Krefman AE; Hedderson MM; Brown SD; Mevi A; Chasan-Taber L; Quesenberry CP; Ferrara A

    Matern Child Health J. 2016 Jun;20(6):1247-57.

    PubMed abstract

    Trimester-Specific Gestational Weight Gain and Infant Size for Gestational Age

    Author(s): Sridhar SB; Xu F; Hedderson MM

    PLoS ONE. 2016;11(7):e0159500. Epub 2016-07-21.

    PubMed abstract

    The Comparative Effectiveness of Diabetes Prevention Strategies to Reduce Postpartum Weight Retention in Women With Gestational Diabetes Mellitus: The Gestational Diabetes' Effects on Moms (GEM) Cluster Randomized Controlled Trial

    Author(s): Ferrara A; Brown SD; Albright CL; Tsai AL; Sternfeld B; Gordon NP; Schmittdiel JA; Gunderson EP; Mevi AA; Quesenberry CP; et al.

    Diabetes Care. 2016 Jan;39(1):65-74. Epub 2015-12-09.

    PubMed abstract

    Pioglitazone Use and Risk of Bladder Cancer and Other Common Cancers in Persons With Diabetes

    Author(s): Lewis JD; Quesenberry CP; Strom BL; Ehrlich SF; Mamtani R; Ferrara A; Ferrara A; et al.

    JAMA. 2015 Jul 21;314(3):265-77.

    PubMed abstract

    Outreach to diversify clinical trial participation: A randomized recruitment study

    Author(s): Brown SD; Partee PN; Feng J; Quesenberry CP; Hedderson MM; Ehrlich SF; Kiernan M; Ferrara A

    Clin Trials. 2015 Jun;12(3):205-11. Epub 2015-02-02.

    PubMed abstract

    Response to Comment on Hedderson et al. Prepregnancy SHBG Concentrations and Risk for Subsequently Developing Gestational Diabetes Mellitus. Diabetes Care 2014;37:1296-1303

    Author(s): Hedderson MM; Ferrara A

    Diabetes Care. 2014 Dec;37(12):e280.

    PubMed abstract

    Genetic Variants in Transcription Factors Are Associated With the Pharmacokinetics and Pharmacodynamics of Metformin

    Author(s): Goswami S; Davis RL; Savic RM; et al.

    Clin Pharmacol Ther. 2014 Sep;96(3):370-9. Epub 2014-05-22.

    PubMed abstract

    Maternal gestational weight gain and offspring risk for childhood overweight or obesity

    Author(s): Sridhar SB; Darbinian J; Ehrlich SF; Markman MA; Gunderson EP; Ferrara A; Hedderson MM

    Am J Obstet Gynecol. 2014 Sep;211(3):259.e1-8. Epub 2014-04-13.

    PubMed abstract

    A Call to Increase Physical Activity Among Women of Reproductive Age: Is It Possible?

    Author(s): Hedderson M; Ferrara A

    JAMA Intern Med. 2014 Jul;174(7):1056-7.

    PubMed abstract

    Pregravid Liver Enzyme Levels and Risk of Gestational Diabetes During a Subsequent Pregnancy

    Author(s): Sridhar SB; Xu F; Darbinian J; Quesenberry CP; Ferrara A; Hedderson MM

    Diabetes Care. 2014 Jul;37(7):1878-84. Epub 2014-05-02.

    PubMed abstract

    Post-partum weight loss and glucose metabolism in women with gestational diabetes: the DEBI Study

    Author(s): Ehrlich SF; Hedderson MM; Quesenberry CP; Feng J; Brown SD; Crites Y; Ferrara A

    Diabet Med. 2014 Jul;31(7):862-7. Epub 2014-03-25.

    PubMed abstract

    Proteinuria testing among patients with diabetes mellitus is associated with bladder cancer diagnosis: potential for unmeasured confounding in studies of pioglitazone and bladder cancer

    Author(s): Lewis JD; Habel L; Quesenberry C; Mamtani R; Peng T; Bilker WB; Hedderson M; Nessel L; Vaughn DJ; Strom BL; Ferrara A

    Pharmacoepidemiol Drug Saf. 2014 Jun;23(6):636-45. Epub 2014-04-25.

    PubMed abstract

    The Multigroup Ethnic Identity Measure-Revised: Measurement Invariance Across Racial and Ethnic Groups

    Author(s): Brown SD; Unger Hu KA; Mevi AA; Hedderson MM; Shan J; Quesenberry CP; Ferrara A

    J Couns Psychol. 2014 Jan;61(1):154-61. Epub 2013-11-04.

    PubMed abstract

    Prepregnancy SHBG Concentrations and Risk for Subsequently Developing Gestational Diabetes Mellitus

    Author(s): Hedderson MM; Xu F; Darbinian JA; Quesenberry CP; Sridhar S; Kim C; Gunderson EP; Ferrara A

    Diabetes Care. 2014;37(5):1296-303. Epub 2014-02-21.

    PubMed abstract

    A pragmatic cluster randomized clinical trial of diabetes prevention strategies for women with gestational diabetes: design and rationale of the Gestational Diabetes' Effects on Moms (GEM) study

    Author(s): Ferrara A; Albright CL; Ehrlich SF; Caan BJ; Sternfeld B; Gordon NP; Schmittdiel JA; Gunderson EP; Mevi AA; Quesenberry CP; et al.

    BMC Pregnancy Childbirth. 2014;14:21. Epub 2014-01-15.

    PubMed abstract

    Low Prepregnancy Adiponectin Concentrations Are Associated With a Marked Increase in Risk for Development of Gestational Diabetes Mellitus

    Author(s): Hedderson MM; Darbinian J; Havel PJ; Quesenberry CP; Sridhar S; Ehrlich S; Ferrara A

    Diabetes Care. 2013 Dec;36(12):3930-7. Epub 2013-08-29.

    PubMed abstract

    Risk of Large-for-Gestational-Age Newborns in Women With Gestational Diabetes by Race and Ethnicity and Body Mass Index Categories

    Author(s): Sridhar SB; Ferrara A; Ehrlich SF; Brown SD; Hedderson MM

    Obstet Gynecol. 2013 Jun;121(6):1255-62.

    PubMed abstract

    Pregnancy Glycemia in Mexican-American Women Without Diabetes or Gestational Diabetes and Programming for Childhood Obesity

    Author(s): Ehrlich SF; Rosas LG; Ferrara A; King JC; Abrams B; Harley KG; Hedderson MM; Eskenazi B

    Am J Epidemiol. 2013 Apr 15;177(8):768-75. Epub 2013 Mar 15.

    PubMed abstract

    Pregnancy Glucose Levels in Women without Diabetes or Gestational Diabetes and Childhood Cardiometabolic Risk at 7 Years of Age

    Author(s): Ehrlich SF; Rosas LG; Ferrara A; King JC; Abrams B; Harley KG; Hedderson MM; Eskenazi B

    J Pediatr. 2012 Dec;161(6):1016-21. Epub 2012 Jul 11.

    PubMed abstract

    Sex ratio variations among the offspring of women with diabetes in pregnancy

    Author(s): Ehrlich SF; Eskenazi B; Hedderson MM; Ferrara A

    Diabet Med. 2012 Sep;29(9):e273-8.

    PubMed abstract

    Racial/Ethnic Disparities in the Prevalence of Gestational Diabetes by BMI

    Author(s): Hedderson M; Ehrlich S; Sridhar S; Darbinian J; Moore S; Ferrara A

    Diabetes Care. 2012 Jul;35(7):1492-8. Epub 2012 May 22.

    PubMed abstract

    Prepregnancy cardiometabolic and inflammatory risk factors and subsequent risk of hypertensive disorders of pregnancy

    Author(s): Hedderson MM; Darbinian JA; Sridhar SB; Quesenberry CP

    Am J Obstet Gynecol. 2012 Jul;207(1):68.e1-9. Epub 2012 May 23.

    PubMed abstract

    Influence of breastfeeding during the postpartum oral glucose tolerance test on plasma glucose and insulin

    Author(s): Gunderson EP; Quesenberry CP; Lo JC; Ferrara A; Sternfeld B; Sternfeld B; et al.

    Obstet Gynecol. 2012 Jul;120(1):136-43.

    PubMed abstract

    Referral to telephonic nurse management improves outcomes in women with gestational diabetes

    Author(s): Ferrara A; Hedderson MM; Ching J; Kim C; Peng T; Crites YM

    Am J Obstet Gynecol. 2012 Jun;206(6):491.e1-5. Epub 2012 Apr 24.

    PubMed abstract

    Lactation Intensity and Postpartum Maternal Glucose Tolerance and Insulin Resistance in Women With Recent GDM: The SWIFT cohort

    Author(s): Gunderson EP; Chiang V; Lo JC; Sternfeld B; Ferrara A; Selby JV; Selby JV; et al.

    Diabetes Care. 2012 Jan;35(1):50-6. Epub 2011 Oct 19.

    PubMed abstract

    A pregnancy and postpartum lifestyle intervention in women with gestational diabetes mellitus reduces diabetes risk factors: a feasibility randomized control trial

    Author(s): Ferrara A; Hedderson MM; Albright CL; Ehrlich SF; Quesenberry CP Jr; Peng T; Feng J; Ching J; Crites Y

    Diabetes Care. 2011 Jul;34(7):1519-25. Epub 2011 May 3.

    PubMed abstract

    Pregravid cardiometabolic risk profile and risk for gestational diabetes mellitus

    Author(s): Hedderson MM; Darbinian JA; Quesenberry CP; Ferrara A

    Am J Obstet Gynecol. 2011 Jul;205(1):55.e1-7. Epub 2011 May 28.

    PubMed abstract

    Change in body mass index between pregnancies and the risk of gestational diabetes in a second pregnancy

    Author(s): Ehrlich SF; Hedderson MM; Feng J; Davenport ER; Gunderson EP; Ferrara A

    Obstet Gynecol. 2011 Jun;117(6):1323-30.

    PubMed abstract

    Risk of bladder cancer among diabetic patients treated with pioglitazone: interim report of a longitudinal cohort study

    Author(s): Lewis JD; Ferrara A; Peng T; Hedderson M; Bilker WB; Quesenberry CP Jr; Vaughn DJ; Nessel L; Selby J; Strom BL

    Diabetes Care. 2011 Apr;34(4):916-22.

    PubMed abstract

    The risk of large for gestational age across increasing categories of pregnancy glycemia

    Author(s): Ehrlich SF; Crites YM; Hedderson MM; Darbinian JA; Ferrara A

    Am J Obstet Gynecol. 2011 Mar;204(3):240.e1-6. Epub 2011 Jan 17.

    PubMed abstract

    Disparities in the risk of gestational diabetes by race-ethnicity and country of birth

    Author(s): Hedderson MM; Darbinian JA; Ferrara A

    Paediatr Perinat Epidemiol. 2010 Sep;24(5):441-8.

    PubMed abstract

    Gestational weight gain and risk of gestational diabetes mellitus

    Author(s): Hedderson MM; Gunderson EP; Ferrara A

    Obstet Gynecol. 2010 Mar;115(3):597-604.

    PubMed abstract

    Contraception before and after GDM

    Author(s): Hedderson M

    In: Kim C, Ferrara A, editors. Gestational diabetes during and after pregnancy. London: Springer; 2010.

    PubMed abstract

    High blood pressure before and during early pregnancy is associated with an increased risk of gestational diabetes mellitus

    Author(s): Hedderson MM; Ferrara A

    Diabetes Care. 2008 Dec;31(12):2362-7. Epub 2008 Sep 22.

    PubMed abstract

    Body mass index and weight gain prior to pregnancy and risk of gestational diabetes mellitus

    Author(s): Hedderson MM; Williams MA; Holt VL; Weiss NS; Ferrara A

    Am J Obstet Gynecol. 2008 Apr;198(4):409.e1-7. Epub 2008 Feb 20.

    PubMed abstract

    Androgenicity of progestins in hormonal contraceptives and the risk of gestational diabetes mellitus

    Author(s): Hedderson MM; Ferrara A; Williams MA; Holt VL; Weiss NS

    Diabetes Care. 2007 May;30(5):1062-8. Epub 2007 Feb 15.

    PubMed abstract

    Pregnancy plasma glucose levels exceeding the American Diabetes Association thresholds, but below the National Diabetes Data Group thresholds for gestational diabetes mellitus, are related to the risk of neonatal macrosomia, hypoglycaemia and hyperbilirubinaemia

    Author(s): Ferrara A; Weiss NS; Hedderson MM; Quesenberry CP Jr; Selby JV; Ergas IJ; Peng T; Escobar GJ; Pettitt DJ; Sacks DA

    Diabetologia. 2007 Feb;50(2):298-306. Epub 2006 Nov 14.

    PubMed abstract

    Pregnancy weight gain and risk of neonatal complications: macrosomia, hypoglycemia, and hyperbilirubinemia

    Author(s): Hedderson MM; Weiss NS; Sacks DA; Pettitt DJ; Selby JV; Quesenberry CP; Ferrara A

    Obstet Gynecol. 2006 Nov;108(5):1153-61.

    PubMed abstract

    An increase in the incidence of gestational diabetes mellitus: Northern California, 1991-2000

    Author(s): Ferrara A; Kahn HS; Quesenberry CP; Riley C; Hedderson MM

    Obstet Gynecol. 2004 Mar;103(3):526-33.

    PubMed abstract

    Gestational diabetes mellitus and lesser degrees of pregnancy hyperglycemia: association with increased risk of spontaneous preterm birth

    Author(s): Hedderson MM; Ferrara A; Sacks DA

    Obstet Gynecol. 2003 Oct;102(4):850-6.

    PubMed abstract

    Allergy and risk of breast cancer among young women (United States)

    Author(s): Hedderson MM; Malone KE; Daling JR; White E

    Cancer Causes Control. 2003 Sep;14(7):619-26.

    PubMed abstract

    Changes in diet, physical activity, and supplement use among adults diagnosed with cancer

    Author(s): Patterson RE; Neuhouser ML; Hedderson MM; Schwartz SM; Standish LJ; Bowen DJ

    J Am Diet Assoc. 2003 Mar;103(3):323-8.

    PubMed abstract

    Prevalence of gestational diabetes mellitus detected by the national diabetes data group or the carpenter and coustan plasma glucose thresholds

    Author(s): Ferrara A; Hedderson MM; Quesenberry CP; Selby JV

    Diabetes Care. 2002 Sep;25(9):1625-30.

    PubMed abstract