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Matthew E. Hirschtritt, MD, MPH

Kaiser Permanente Researcher Profiles

Matthew  Hirschtritt, MD, MPH

Matthew Hirschtritt is a physician researcher with The Permanente Medical Group Delivery Science & Applied Research Physician Researcher Program. He is also an Associate Physician in the Department of Psychiatry of The Permanente Medical Group (Oakland, CA), an Adjunct Investigator in the Kaiser Permanente Division of Research, and Assistant Program Director for Research in the Kaiser Permanente Oakland Psychiatry Residency Training Program. He is also a Volunteer Assistant Clinical Professor in the UCSF Department of Psychiatry and the UCSF Weill Institute for Neurosciences. The overarching goals of his research include improving equitable access to, quality of, and cost-effectiveness of mental health detection and treatment, focusing on underserved and marginalized communities.

Dr. Hirschtritt’s investigative work has involved diverse mental health-related topics, including characteristics and treatments for obsessive-compulsive disorder, Tourette syndrome, adolescent depression and attention-deficit/hyperactivity disorder, and substance use disorders. His work has also examined the interrelationship between adolescent resiliency, peer victimization, and suicidal ideation. More recently, his work has focused on the distribution, provision, and quality of mental health care in the United States, which has involved addressing mental health stigma (specifically the harmful implications of attributing gun violence exclusively to mental illness) and psychotropic prescription patterns using nationally representative data.

In addition to his research experience, Dr. Hirschtritt has worked in various clinical psychiatric settings, including inpatient units in a safety-net, academically affiliated, and private hospitals, psychiatric emergency services, and outpatient services (including interdisciplinary clinics focused on the needs of sexual minority adults and young adults with new- or recent-onset psychosis). He is an enthusiastic educator, having designed an online curriculum for the National Neuroscience Curriculum Initiative.

Following completion of his undergraduate degree in psychology from Cornell University, Dr. Hirschtritt joined the National Institute of Mental Health as an Intramural Research Training Award recipient. He then completed his pre-medical, postbaccalaureate coursework at Johns Hopkins University, and, before beginning medical school, served as a research associate in the Yale Child Study Center. As a student in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, a five-year program dedicated to training clinician-scientists, Dr. Hirschtritt completed additional coursework in public health (leading to an MPH degree), and first came to UCSF as a Doris Duke Clinical Scholar, where he completed residency training in adult psychiatry and fellowship training in forensic psychiatry.


A Model to Predict Psychosis Risk from Electronic Health Records Using Natural Language Processing and Machine Learning

This study will apply sentiment analysis — a form of natural language processing — to electronic health records to create a risk score for psychosis among adolescent and young adult Kaiser Permanente members. The findings will be used to establish a foundation for technology-assisted identification of at-risk patients and to offer these patients information and resources to address psychotic symptoms.

Investigator: Hirschtritt, Matthew

Funder: Garfield Memorial Fund


Experiences of transgender and gender diverse patients in emergency psychiatric settings: A scoping review

Authors: O'Brien, Megan;Hirschtritt, Matthew E;Tahir, Peggy;Kalapatapu, Raj K

J Am Coll Emerg Physicians Open. 2023 Aug;4(4):e13018. Epub 2023-08-03.

PubMed abstract

Improving Internal Medicine Residents’ Comfort Managing Psychiatric Conditions Through an Interactive, Case-Based Workshop

Authors: Patel, Rushi;Ramalingam, Nirmala D;Pal, Anish;Tran, H Nicole;Hirschtritt, Matthew E

Acad Psychiatry. 2023 Aug;47(4):450-451. Epub 2023-05-18.

PubMed abstract

Burnout Among Psychiatry Residents and One Program’s Approach to Creating a Culture of Wellness

Authors: Brown, Kathryn H;Bal, Berneen;Plauche, Jessica L;Sung, Dawn;Hirschtritt, Matthew E

Perm J. 2023 Jun 15;27(2):137-141. Epub 2023-05-22.

PubMed abstract

Exploring the Complex Associations Between Prenatal and Early-Life Infections and Obsessive-Compulsive and Tic-Related Disorders

Authors: Hirschtritt, Matthew E;Mathews, Carol A

Biol Psychiatry. 2023 Jun 01;93(11):959-961.

PubMed abstract

Patient and Visit Characteristics Associated With Physical Restraint Use in the Emergency Department

Authors: Walia, Harbir; Tucker, Lue-Yen S; Manickam, Raj N; Kene, Mamata V; Sharp, Adam L; Berdahl, Carl T; Hirschtritt, Matthew E

Perm J. 2023 Mar 15;27(1):94-102. Epub 2022-12-04.

PubMed abstract

What Will It Take to Meet Adolescents’ Mental Health Needs?

Authors: Hirschtritt, Matthew E; Rodgers, Caryn R R

J Adolesc Health. 2023 Feb;72(2):175-176.

PubMed abstract

A Brief Course on Forensic Psychiatry Principles

Authors: Weiner, Stephen; Lingafelter, Nathan; Ali, Musaab; Wu, Johnathan; Walia, Harbir; Wasser, Tobias; Hirschtritt, Matthew E

Acad Psychiatry. 2023 Feb;47(1):107-108. Epub 2022-07-19.

PubMed abstract

Fulfilling the Goals of 988 Through Crisis Stabilization Care

Authors: Hirschtritt, Matthew E; Howard, Caren A; Simon, Gregory E

Psychiatr Serv. 2023 Jan 31:appips20220503.

PubMed abstract

Walking the Benzodiazepine High Wire

Authors: Kroenke, Kurt; Hirschtritt, Matthew E

Psychiatr Serv. 2023 Jan 01;74(1):73-75. Epub 2022-11-02.

PubMed abstract

Electroconvulsive Therapy Anesthetic Choice and Clinical Outcomes

Authors: Li, Kevin J; Slama, Natalie E; Hirschtritt, Matthew E; Anshu, Prachi; Iturralde, Esti

J ECT. 2022 Dec 09.

PubMed abstract

A Novel Introduction to Transgender and Nonbinary Mental Health

Authors: Frawley, Erin M; Norris, Ryan; Chen, Ingrid L; Hirschtritt, Matthew E

Acad Psychiatry. 2022 Dec;46(6):787-788. Epub 2022-05-03.

PubMed abstract

Cost-Effectiveness of Motivational Interviewing to Reduce Alcohol and Cannabis Use Among Patients With Depression

Authors: Satre, Derek D; Parthasarathy, Sujaya; Young-Wolff, Kelly C; Meacham, Meredith C; Borsari, Brian; Hirschtritt, Matthew E; Van Dyke, Lucas; Sterling, Stacy A

J Stud Alcohol Drugs. 2022 Sep;83(5):662-671.

PubMed abstract

Association Between Prenatal Cannabis Use and Psychotropic Medication Use in Pregnant Patients With Depression and Anxiety

Authors: Hirschtritt, Matthew E; Avalos, Lyndsay A; Sarovar, Varada; Ridout, Kathryn K; Goler, Nancy C; Ansley, Deborah R; Satre, Derek D; Young-Wolff, Kelly C

J Addict Med. 2022 Jul-Aug 01;16(4):e269-e273. Epub 2022-01-22.

PubMed abstract

Agreement between Youth Self-Report and Biospecimen-Confirmed Substance Use: A Systematic Review

Authors: Folk, Johanna B; Hirschtritt, Matthew E; McCrary, Quincy D; Kalapatapu, Raj K

Subst Use Misuse. 2022;57(4):531-538. Epub 2022-01-04.

PubMed abstract

Psychotropic medication prescribing during the COVID-19 pandemic

Authors: Hirschtritt, Matthew E; Slama, Natalie; Sterling, Stacy A; Olfson, Mark; Iturralde, Esti

Medicine (Baltimore). 2021 Oct 29;100(43):e27664.

PubMed abstract

Trends in Ethnicity, Race, and Sex Among Psychiatry and Non-psychiatry Residency Applicants, 2008-2019

Authors: Chen, Ingrid L; Koleilat, Issam; Choinski, Krystina; Phair, John; Hirschtritt, Matthew E

Acad Psychiatry. 2021 Aug;45(4):445-450. Epub 2021-04-06.

PubMed abstract

Cannabis Use Among Patients With Psychotic Disorders

Authors: Hirschtritt, Matthew E; Young-Wolff, Kelly C; Mathalon, Daniel H; Satre, Derek D

Perm J. 2021 05 12;25. Epub 2021-05-12.

PubMed abstract

Mental Health Services in a U.S. Prison During the COVID-19 Pandemic

Authors: Burton, Paul R S; Morris, Nathaniel P; Hirschtritt, Matthew E

Psychiatr Serv. 2021 04 01;72(4):458-460. Epub 2021-01-05.

PubMed abstract

Telepsychiatry, Hospitals, and the COVID-19 Pandemic

Authors: Morris, Nathaniel P; Hirschtritt, Matthew E

Psychiatr Serv. 2020 12 01;71(12):1309-1312. Epub 2020-09-16.

PubMed abstract

Are Substance Use and Bullying Perpetration Two Sides of the Same Coin?

Authors: Hirschtritt, Matthew E

J Adolesc Health. 2020 09;67(3):311-312.

PubMed abstract

Drug Formularies in Correctional Settings

Authors: Morris NP; Hirschtritt ME; Tamburello AC

J Am Acad Psychiatry Law. 2020 03;48(1):2-6.

PubMed abstract

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