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Carlos Iribarren, MD, MPH, PhD

carlos.iribarren@kp.org

Kaiser Permanente Researcher Profiles

Iribarren, Carlos

Carlos Iribarren MD, MPH, PhD, is a Research Scientist at the Kaiser Permanente Northern California Division of Research and an adjunct Assistant Professor in the Department of Epidemiology and Biostatistics at the University of California, San Francisco (UCSF). He joined the Division of Research in 1997, and started at UCSF in 1998. A clinical epidemiologist, Dr. Iribarren’s current research interests include risk stratification in the primary prevention setting, including genomic, imaging, and blood biomarkers, and the epidemiology of ECG traits (particularly QT interval) and chronic lung disease (asthma, interstitial pulmonary fibrosis). Dr. Iribarren was a standing member and co-chair of the NIH Cardiovascular, Heart and Sleep Study Section (CHS-B) from 2017-2021 and has participated in numerous other study sections, such as the American Heart Association Behavioral Science, Epidemiology, and Prevention Study Section. He is a Consultant for the Health Care Advisors and for Abbott Diagnostics. He was a Fulbright Fellow at the University of Southern California, Los Angeles, from 1989 through 1994. Dr. Iribarren has published over 210 peer-reviewed articles.

Current Positions

  • Research Scientist III, Division of Research, Kaiser Permanente Northern California
  • Adjunct Assistant Professor, Department of Epidemiology and Biostatistics, University of California, San Francisco

Section Affiliations

Primary Research Interests

  • Cardiovascular epidemiology
  • Genetic determinants of coronary heart disease
  • Vascular calcification
  • Psychosocial factors in coronary disease
  • Smoking-related diseases
  • Inflammation and endothelial function
  • Congestive heart failure in diabetes

Studies

Polygenic risk for early-onset coronary heart disease

Polygenic risk for early-onset coronary heart disease
Using the GERA cohort, we propose to investigate the association of a validated 12-SNP polygenic risk score (PRS) with risk of early-onset coronary heart disease (CHD), defined as acute myocardial infarction, revascularization procedure or CHD death in men before age 50 and in women before age 60. The hypothesis is that the PRS will have a stronger association with early-onset vs. late-onset CHD, highlighting the importance of primary prevention early in life.
Funder: The Permanente Medical Group

Investigator: Iribarren, Carlos

Funder: TPMG Targeted Analysis Program (TAP)

Genetic and social determinants of pharmacological health outcomes in ancestrally diverse populations

The overarching objective of this proposal is to discover genetic and social determinants of drug safety and efficacy in previously-understudied populations using electronic health record (EHR)-linked biobanks. Aims include determining the impact of social factors on drug effects, identifying genome-wide polymorphisms predictive of drug effects in historically-excluded populations, and discovering eQTL determinants of drug response.

Investigator: Iribarren, Carlos

Funder: National Human Genome Research Institute

Genetic and Environmental Factors in Hyperlipidemia and Its Treatment

Study has 3 aims: Identify and characterize common and rare genetic variants and environmental factors underlying untreated LDL-cholesterol, HDL-cholesterol, triglycerides and total cholesterol in each of four race/ethnicity groups; identify common and rare genetic variants and environmental factors underlying response to statin and fibrate treatment of lipidemia; and characterize gene-environment interactions underlying plasma lipoprotein concentrations and their treatment.

Investigator: Iribarren, Carlos

Funder: University of California, San Francisco, Project Grant

Optimization of statin regimens for atherosclerotic cardiovascular disease prevention using polygenic risk scores and real-world evidence

This study will use the GERA cohort to develop a polygenic risk score-guided precision medicine tool for statin treatment decisions. It will develop an algorithm that predicts baseline atherosclerotic cardiovascular disease (ASCVD) and statin-induced ASCVD relative risk reduction incorporating ASCVD polygenic risk score on top of traditional ASCVD risk prediction tools.

Investigator: Iribarren, Carlos

Funder: National Heart, Lung, and Blood Institute

Polygenic Risk Scores for Advancing CVD Risk Stratification among Asymptomatic Adults

Leveraging the GERA Cohort to evaluate the performance of a 12-SNP PRS for CVD against the Pool Cohorts Equation across ethnic groups; validate MEGASTROKE Consortium PRS_32 for ischemic stroke; and assess the interplay between genetic background and lifestyle factors. We will evaluate the independent and joint contributions of PRS_12, smoking status, Mediterranean diet pattern and meeting physical activity recommendations to risk of CVD. Separate analyses for each ethnic group.

Investigator: Iribarren, Carlos

Funder: GENinCode PLC

Community-based, Longitudinal Cohort of Patients with Interstitial Lung Disease (ILD) in the Kaiser Permanente Northern California (KPNC) Health System

The KPNC-ILD cohort will consist of approximately 10,000 patients with interstitial lung disease. It will be built through electronic health recordbased case identification using an algorithm that will be further developed. We anticipate optimizing the existing KPNC-ILD algorithm and having a fully operational case identification process. The KPNC-ILD algorithm will be useful to clinical researchers worldwide who are interested in using large electronic health recordbased datasets to identify ILD cohorts.

Investigator: Iribarren, Carlos

Funder: Genentech, Inc.

Community-Based, Longitudinal cohort of Patients with Interstitial Lung Disease in the Kaiser Permanente Northern California Health System

The study aim is to optimize the Kaiser Permanente Northern California (KPNC) Interstitial Lung Disease (ILD) algorithm and establish the KPNC-ILD cohort. The KPNC-ILD cohort will consist of approximately 10,000 patients with ILD. It will be built through electronic health record-based case identification using an algorithm. We will optimize the existing algorithm and have a fully operational case identification process to build the cohort. The algorithm will be useful to clinical researchers worldwide who are interested in using large, electronic health record-based datasets to identify ILD cohorts.

Investigator: Iribarren, Carlos

Funder: Genentech, Inc.

MINERVA Biomarkers Substudy

We will conduct assays of a selected panel of cardiac, metabolic, and cancer biomarkers in 3,000 blood samples collected by the MINERVA (MultIethNic Study of BrEast ARterial Calcium Gradation and CardioVAscular Disease) Study and stored at the Kaiser Biobank. The biomarker data will be merged with the study datasets to perform association analyses with risk factors and outcomes. The proposed biomarker panel incudes Cystatin C, apolipoprotein A1, apolipoprotein B, Lp(a), BNP, Gamma prime fibrinogen, SuPAR, Galectin-3, hs-troponin, and a cancer biomarker panel.

Investigator: Iribarren, Carlos

Funder: Abbott Laboratories

Population-Based Pharmacogenomic Assessment of QT Prolongation

​Cardiotoxicity of commonly prescribed medications, typically assessed by electrocardiographic features such as prolongation of the QT interval, has regulatory effects and is associated with potentially fatal outcomes. This project aims to advance understanding of the genetic basis for drug cardiotoxicity and its downstream consequences by leveraging the extensive data resources of the Kaiser Permanente Northern California Research Program on Genes, Environment and Health (RPGEH), and the ability to link these data to other health plan databases, namely Kaiser Permanente Northern California’s pharmacy, electrocardiogram, and outpatient/inpatient utilization databases. Longitudinal analyses of the QT interval over up to 20 years will be conducted in the large and ethnically diverse Genetic Epidemiology Research in Adult Health and Aging (GERA) cohort of the RPGEH. Genetic loci that influence adverse drug reactions will be identified and characterized, and the associated biological pathways and tissues will be investigated. This study will also examine: a) genetic predictors of adverse outcomes (e.g., ventricular arrhythmias and Torsade de Pointes), b) whether the identified gene-by-drug interactions are associated with these adverse outcomes, and c) degree of mediation by QTc prolongation.

Investigator: Iribarren, Carlos

Funder: National Heart, Lung, and Blood Institute

Multiethnic Study of Breast Arterial Calcium Gradation and CVD

Specific study aims are: 1) To establish a multi-ethnic cohort between the ages of 60 and 79 years with equal representation of white, African-American, Asian and Hispanic/Latina women. All participants will be recruited at the time of their regular screening mammography and will be free of clinical CVD at baseline. A new, validated densitometry method will be used to estimate BAC mass (in milligrams) using digital mammograms; 2) To document race/ethnic variation in BAC mass and to examine associations of BAC mass with sociodemographic background, family history of CVD, traditional and novel CVD risk factors, reproductive health factors, psychosocial factors, selected mineral metabolism factors, selected medication use (statins and nitrogen-containing bisphosphonates), breast size and sleep-related factors; and 3) To elucidate the role of BAC mass in the prediction of coronary heart disease (CHD), cerebrovascular disease, heart failure, peripheral vascular disease and total CVD and to determine whether adding BAC mass to prediction models based on traditional risk factors improves classification of risk for total CVD and its components. Accomplishing these aims will provide novel insights into the utility of BAC mass as a screening tool to assess CVD risk.

Investigator: Iribarren, Carlos

Funder: National Heart, Lung, and Blood Institute

Genomics of Blood Pressure-induced Target Organ Damage

The study’s aims are to: 1) ascertain the genomic contribution of common genetic variants to blood pressure (BP) variation within and between multiple ethnic groups; 2) conduct Mendelian randomization experiments using all new and known BP-associated variants to investigate the interplay of genetic BP risk with hypertensive target organ damage including left ventricular hypertrophy, renal dysfunction, and clinical cardiovascular disease across ethnic groups; and 3) perform deep whole-genome sequencing in very extreme individuals for systolic blood pressure to uncover the entire spectrum of allele frequencies.

Investigator: Iribarren, Carlos

Funder: National Heart, Lung, and Blood Institute

Defining a Comprehensive Reference Profile of Circulating Human Extracellular RNA: A CARDIA Ancillary Study

Blood and other body fluids harbor abundant and stable extracellular RNAs (exRNA) which are increasingly recognized as novel potential biomarkers of disease. This study has the main objective of generating reference profiles of both short and long non-coding regulatory exRNA, including environmentally-derived exRNA, from 720 plasma samples collected at the 10-year CARDIA visit. These healthy subjects will be stratified as follows: 180 subjects in each of the following 4 groups: male Caucasian, female Caucasian, male African American, female African American.

Investigator: Iribarren, Carlos

Funder: National Heart, Lung, and Blood Institute

Pharmacogenomics of Statin Therapy

This study will recruit statin users with: 1) a major acute coronary event (n=150), 2) new onset type 2 diabetes (n=150), 3) statin-induced myopathy (n=150), and controls free of all 3 conditions (n=300). We will then conduct genetic, transcriptomic, proteomic and/or metabolic profiling studies to identify biomarkers of statin response and side effects. We will use prescription fills and ICD-9 codes to identify statin users who are current Kaiser members that meet one of the three conditions described above. For each condition, a frequency-matched control group will be formed. Recruited individuals will complete a self-reported survey and provide a blood sample from which an aliquot will be used to generate a lymphoblastoid cell line. A separate aliquot will be used to store frozen viable cells for the future creation of ips cells, and plasma and DNA will be stored.

Investigator: Iribarren, Carlos

Funder: National Institute of General Medical Sciences

Lung Function Decline and Disease Risk from Young Adulthood to Middle Age

This study will take advantage of longitudinal data collection in CARDIA to evaluate the association between lung function and risk of future lung disease and cardiovascular disease. The study will perform spirometry in all CARDIA participants at the year 30 examination, and test the hypothesis that individuals with accelerated decline in lung function are at risk for both pulmonary (COPD) and cardiovascular (hypertension, diastolic heart dysfunction, coronary artery disease, and heart failure) diseases.

Investigator: Iribarren, Carlos

Funder: National Heart, Lung, and Blood Institute

Publications

X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

Authors: Zhang, Peixiang;Iribarren, Carlos;Reue, Karen;et al.

Nat Commun. 2024 Jul 02;15(1):5571. Epub 2024-07-02.

PubMed abstract

Identification of the Molecular Components of Enhancer-Mediated Gene Expression Variation in Multiple Tissues Regulating Blood Pressure

Authors: Yaacov, Or;Mathiyalagan, Prabhu;Berk-Rauch, Hanna E;Ganesh, Santhi K;Zhu, Luke;Hoffmann, Thomas J;Iribarren, Carlos;Risch, Neil;Lee, Dongwon;Chakravarti, Aravinda

Hypertension. 2024 Jul;81(7):1500-1510. Epub 2024-05-15.

PubMed abstract

Polygenic risk and incident coronary heart disease in a large multiethnic cohort

Authors: Iribarren, Carlos;Lu, Meng;Elosua, Roberto;Gulati, Martha;Wong, Nathan D;Blumenthal, Roger S;Nissen, Steven;Rana, Jamal S

Am J Prev Cardiol. 2024 Jun;18:100661. Epub 2024-03-28.

PubMed abstract

Sex-specific genetic architecture of blood pressure

Authors: Yang, Min-Lee;Xu, Chang;Gupte, Trisha;Hoffmann, Thomas J;Iribarren, Carlos;Zhou, Xiang;Ganesh, Santhi K

Nat Med. 2024 Mar;30(3):818-828. Epub 2024-03-08.

PubMed abstract

Diet quality and cardiovascular disease risk among breast cancer survivors in the Pathways Study

Authors: Ergas, Isaac J;Kushi, Lawrence H;Iribarren, Carlos;Nguyen-Huynh, Mai;Rana, Jamal S;Quesenberry, Charles P;Kwan, Marilyn L;Kwan, Marilyn L;et al.

JNCI Cancer Spectr. 2024 Feb 29;8(2).

PubMed abstract

Asthma exacerbations and eosinophilia in the UK Biobank: a genome-wide association study

Authors: Edris, Ahmed;Voorhies, Kirsten;Lutz, Sharon M;Iribarren, Carlos;Hall, Ian;Wu, Ann Chen;Tobin, Martin;Fawcett, Katherine;Lahousse, Lies

ERJ Open Res. 2024 Jan;10(1). Epub 2024-01-08.

PubMed abstract

Adherence to cardiovascular medications and risk of cardiovascular disease in breast cancer patients: A causal inference approach in the Pathways Heart Study

Authors: Kwan, Marilyn L;Iribarren, Carlos;Rana, Jamal S;Nguyen-Huynh, Mai;Kushi, Lawrence H;Neugebauer, Romain;Neugebauer, Romain;et al.

PLoS One. 2024;19(9):e0310531. Epub 2024-09-19.

PubMed abstract

Polygenic risk scores identify heterogeneity in asthma and chronic obstructive pulmonary disease

Authors: Moll, Matthew;Aschard, Hugues;Cho, Michael H;et al.

J Allergy Clin Immunol. 2023 Aug 16.

PubMed abstract

Genetic insights into resting heart rate and its role in cardiovascular disease

Authors: van de Vegte, Yordi J;Witte, Daniel R;van der Harst, Pim;et al.

Nat Commun. 2023 Aug 02;14(1):4646. Epub 2023-08-02.

PubMed abstract

Neighborhood attributes and cardiovascular disease risk in breast cancer survivors: The Pathways Study

Authors: Conroy, Shannon M;Von Behren, Julie;Kwan, Marilyn L;Kim, Mi-Ok;Shariff-Marco, Salma;et al.

Cancer. 2023 Aug 01;129(15):2395-2408. Epub 2023-04-25.

PubMed abstract

Development of cardiometabolic risk factors following endocrine therapy in women with breast cancer

Authors: Rillamas-Sun, Eileen;Kwan, Marilyn L;Cheng, Richard;Neugebauer, Romain;Rana, Jamal S;Hershman, Dawn L;Greenlee, Heather;et al.

Breast Cancer Res Treat. 2023 Aug;201(1):117-126. Epub 2023-06-16.

PubMed abstract

Novel genetic variants associated with inhaled corticosteroid treatment response in older adults with asthma

Authors: Wang, Alberta L; Iribarren, Carlos; Wu, Ann C; et al.

Thorax. 2023 May;78(5):432-441. Epub 2022-05-02.

PubMed abstract

Development and application of an algorithm for statin-induced myopathy based on electronic health record-derived structured elements

Authors: Oni-Orisan, Akinyemi;Lu, Meng;Peng, Jonathan A;Krauss, Ronald M;Iribarren, Carlos;Medina, Marisa W

medRxiv. 2023 Apr 25.

PubMed abstract

Development of cardiometabolic risk factors following endocrine therapy in women with breast cancer

Authors: Rillamas-Sun, Eileen; Kwan, Marilyn L; Iribarren, Carlos; Neugebauer, Romain; Rana, Jamal S; Nguyen-Huynh, Mai; Kushi, Lawrence H; Greenlee, Heather; et al.

Res Sq. 2023 Mar 22.

PubMed abstract

Breast arterial calcification is associated with incident atrial fibrillation among older but not younger post-menopausal women

Authors: Iribarren, Carlos; Chandra, Malini; Parikh, Rishi V; Sanchez, Gabriela; Sam, Danny L; Azamian, Farima Faith; Cho, Hyo-Min; Ding, Huanjun; Molloi, Sabee; Go, Alan S

Eur Heart J Open. 2023 Mar;3(2):oead017. Epub 2023-02-28.

PubMed abstract

Extracting patient-level data from the electronic health record: Expanding opportunities for health system research

Authors: Farrand, Erica; Collard, Harold R; Guarnieri, Michael; Minowada, George; Block, Lawrence; Lee, Mei; Iribarren, Carlos

PLoS One. 2023;18(3):e0280342. Epub 2023-03-10.

PubMed abstract

Asthma and COVID-19 Outcomes: A Prospective Study in a Large Health Care Delivery System

Authors: Finkas, Lindsay K;Ramesh, Navneet;Block, Lawrence S;Yu, Bing Q;Lee, Mei-Tsung;Lu, Meng;Skarbinski, Jacek;Iribarren, Carlos

J Asthma Allergy. 2023;16:1041-1051. Epub 2023-09-26.

PubMed abstract

Reply to M.S. Ewer et al

Authors: Greenlee, Heather; Rillamas-Sun, Eileen; Cheng, Richard; Iribarren, Carlos; Rana, Jamal S; Nguyen-Huynh, Mai; Kushi, Lawrence H; Kwan, Marilyn L

J Clin Oncol. 2022 Dec 10;40(35):4159-4160. Epub 2022-07-25.

PubMed abstract

High-sensitivity troponin I is associated with cardiovascular outcomes but not with breast arterial calcification among postmenopausal women

Authors: Iribarren, Carlos; Chandra, Malini; Lee, Catherine; Sanchez, Gabriela; Sam, Danny L; Azamian, Farima Faith; Cho, Hyo-Min; Ding, Huanjun; Wong, Nathan D; Molloi, Sabee

Int J Cardiol Cardiovasc Risk Prev. 2022 Dec;15:200157. Epub 2022-11-01.

PubMed abstract

A large genome-wide association study of QT interval length utilizing electronic health records

Authors: Hoffmann, Thomas J; Lu, Meng; Oni-Orisan, Akinyemi; Lee, Catherine; Risch, Neil; Iribarren, Carlos

Genetics. 2022 Nov 30;222(4).

PubMed abstract

Polygenic risk score and statin relative risk reduction for primary prevention of myocardial infarction in a real-world population

Authors: Oni-Orisan, Akinyemi; Haldar, Tanushree; Cayabyab, Mari A S; Ranatunga, Dilrini K; Hoffmann, Thomas J; Iribarren, Carlos; Krauss, Ronald M; Risch, Neil

Clin Pharmacol Ther. 2022 Nov;112(5):1070-1078. Epub 2022-08-24.

PubMed abstract

Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort

Authors: Haldar, Tanushree; Oni-Orisan, Akinyemi; Hoffmann, Thomas J; Schaefer, Catherine; Iribarren, Carlos; Krauss, Ronald M; Medina, Marisa W; Risch, Neil

Cardiovasc Diabetol. 2022 Jul 14;21(1):132. Epub 2022-07-14.

PubMed abstract

Risk of heart failure with preserved versus reduced ejection fraction in women with breast cancer

Authors: Kwan, Marilyn L; Cheng, Richard K; Iribarren, Carlos; Shen, Hanjie; Laurent, Cecile A; Roh, Janise M; Hershman, Dawn L; Kushi, Lawrence H; Greenlee, Heather; Rana, Jamal S

Breast Cancer Res Treat. 2022 Jun;193(3):669-675. Epub 2022-04-16.

PubMed abstract

Multiomics Analysis Identifies BIRC3 as a Novel Glucocorticoid Response-Associated Gene

Authors: Kan, Mengyuan; Lu, Meng X; Himes, Blanca E; et al.

J Allergy Clin Immunol. 2022 06;149(6):1981-1991. Epub 2021-12-28.

PubMed abstract

Usage of long-acting muscarinic antagonists and biologics as add-on therapy for patients in the United States with moderate-to-severe asthma

Authors: Spain, C Victor; Dayal, Parul; Ding, Yingjie; Iribarren, Carlos; Omachi, Theodore A; Chen, Hubert

J Asthma. 2022 06;59(6):1237-1247. Epub 2021-05-22.

PubMed abstract

Risk of Cardiovascular Disease in Women With and Without Breast Cancer: The Pathways Heart Study

Authors: Greenlee, Heather; Rana, Jamal S; Cheng, Richard; Rillamas-Sun, Eileen; Neugebauer, Romain; Kwan, Marilyn L; Kwan, Marilyn L; et al.

J Clin Oncol. 2022 05 20;40(15):1647-1658. Epub 2022-04-06.

PubMed abstract

Risk of Cardiometabolic Risk Factors in Women With and Without a History of Breast Cancer: The Pathways Heart Study

Authors: Kwan, Marilyn L; Iribarren, Carlos; Neugebauer, Romain; Rana, Jamal S; Nguyen-Huynh, Mai; Kushi, Lawrence H; Greenlee, Heather; et al.

J Clin Oncol. 2022 05 20;40(15):1635-1646. Epub 2022-01-13.

PubMed abstract

Genetic associations and architecture of asthma-chronic obstructive pulmonary disease overlap

Authors: John, Catherine; Iribarren, Carlos; Tesfaigzi, Yohannes; Tobin, Martin D; et al.

Chest. 2022 05;161(5):1155-1166. Epub 2022-01-31.

PubMed abstract

Breast Arterial Calcification: a Novel Cardiovascular Risk Enhancer Among Postmenopausal Women

Authors: Iribarren, Carlos; Chandra, Malini; Lee, Catherine; Sanchez, Gabriela; Sam, Danny L; Azamian, Farima Faith; Cho, Hyo-Min; Ding, Huanjun; Wong, Nathan D; Molloi, Sabee

Circ Cardiovasc Imaging. 2022 03;15(3):e013526. Epub 2022-03-15.

PubMed abstract

Undifferentiated Induced Pluripotent Stem Cells as a Genetic Model for Nonalcoholic Fatty Liver Disease

Authors: Muñoz, Antonio; Iribarren, Carlos; Medina, Marisa W; et al.

Cell Mol Gastroenterol Hepatol. 2022;14(5):1174-1176.e6. Epub 2022-07-19.

PubMed abstract

Torsade de pointes: A nested case-control study in an integrated healthcare delivery system

Authors: Mantri, Neha; Lu, Meng; Zaroff, Jonathan G; Risch, Neil; Hoffmann, Thomas; Oni-Orisan, Akinyemi; Lee, Catherine; Iribarren, Carlos

Ann Noninvasive Electrocardiol. 2022 01;27(1):e12888. Epub 2021-09-21.

PubMed abstract

Pharmacogenetics of inhaled corticosteroids and exacerbation risk in adults with asthma

Authors: Edris, Ahmed; de Roos, Emmely W; McGeachie, Michael J; Verhamme, Katia M C; Brusselle, Guy G; Tantisira, Kelan G; Iribarren, Carlos; Lu, Meng; Wu, Ann Chen; Stricker, Bruno H; Lahousse, Lies

Clin Exp Allergy. 2022 01;52(1):33-45. Epub 2021-01-25.

PubMed abstract

A Polygenic Risk Score for Asthma in a Large Racially Diverse Population

Authors: Sordillo, Joanne E; McGeachie, Michael; Wu, Ann Chen; et al.

Clin Exp Allergy. 2021 11;51(11):1410-1420. Epub 2021-09-05.

PubMed abstract

QT Interval Dynamics and Cardiovascular Outcomes: A Cohort Study in an Integrated Health Care Delivery System

Authors: Mantri, Neha; Lu, Meng; Zaroff, Jonathan G; Risch, Neil; Hoffmann, Thomas; Oni-Orisan, Akinyemi; Lee, Catherine; Jorgenson, Eric; Iribarren, Carlos

J Am Heart Assoc. 2021 10 05;10(19):e018513. Epub 2021-09-28.

PubMed abstract

Effect of SLCO1B1 T521C on Statin-related Myotoxicity with Use of Lovastatin and Atorvastatin

Authors: Lu, Brian; Sun, Laura; Seraydarian, Manuel; Hoffmann, Thomas J; Medina, Marisa W; Risch, Neil; Iribarren, Carlos; Krauss, Ronald M; Oni-Orisan, Akinyemi

Clin Pharmacol Ther. 2021 09;110(3):733-740. Epub 2021-07-23.

PubMed abstract

Rates of Major Cardiovascular Events in Severe Asthma: US Real-World and Clinical Trial-Eligible Populations

Authors: Dayal, Parul; Iribarren, Carlos; Cheung, Dorothy; Rothenberg, Michael E; Spain, C Victor

Ann Am Thorac Soc. 2021 09;18(9):1580-1584.

PubMed abstract

Breast Arterial Calcification Is Not Associated with Mild Cognitive Impairment or Incident All-Cause Dementia Among Postmenopausal Women: The MINERVA Study

Authors: Iribarren, Carlos; Chandra, Malini; Molloi, Sabee; Sanchez, Gabriela; Azamian-Bidgoli, Fatemeh; Cho, Hyo-Min; Ding, Huanjun; Yaffe, Kristine

J Womens Health (Larchmt). 2021 06;30(6):848-856. Epub 2020-12-07.

PubMed abstract

Magnesium intake was inversely associated with hostility among American young adults

Authors: Lyu, Chen; Tsinovoi, Cari L; Xun, Pengcheng; Song, Yiqing; Pu, Yongjia; Rosanoff, Andrea; Iribarren, Carlos; Schreiner, Pamela J; Shikany, James M; Jacobs, David R; Kahe, Ka

Nutr Res. 2021 05;89:35-44. Epub 2021-04-21.

PubMed abstract

The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change

Authors: Oni-Orisan A; Haldar T; Ranatunga DK; Medina MW; Schaefer C; Krauss RM; Iribarren C; Risch N; Hoffmann TJ

NPJ Genom Med. 2020 Jan 16;5(1):1. Epub 2020-01-16.

PubMed abstract

Impact of idiopathic pulmonary fibrosis on longitudinal healthcare utilization in a community-based cohort of patients

Authors: Farrand E; Iribarren C; Vittinghoff E; Levine-Hall T; Ley B; Minowada G; Collard HR

Chest. 2021 01;159(1):219-227. Epub 2020-07-24.

PubMed abstract

Occupation versus environmental factors in hypersensitivity pneumonitis: population attributable fraction

Authors: Barnes, Hayley; Olin, Anna-Carin; Torén, Kjell; McSharry, Charles; Donnelly, Iona; Lärstad, Mona; Iribarren, Carlos; Quinlan, Patricia; Blanc, Paul D

ERJ Open Res. 2020 Oct;6(4). Epub 2020-10-05.

PubMed abstract

Analysis of putative cis-regulatory elements regulating blood pressure variation

Authors: Nandakumar P; Kwok PY; Risch N; Chakravarti A; Chakravarti A; et al.

Hum Mol Genet. 2020 07 21;29(11):1922-1932.

PubMed abstract

Real-Life Patterns of Exacerbations While on Inhaled Corticosteroids and Long-Acting Beta Agonists for Asthma over 15 Years

Authors: McGeachie MJ; Wang AL; Lutz SM; Sordillo JE; Weiss ST; Tantisira KG; Iribarren C; Lu MX; Wu AC

J Clin Med. 2020 Mar 18;9(3). Epub 2020-03-18.

PubMed abstract

No Association Between Bone Mineral Density and Breast Arterial Calcification Among Postmenopausal Women

Authors: Iribarren C; Chandra M; Molloi S; Sam D; Sanchez G; Bidgoli FA; Cho HM; Ding H; Lo JC

J Endocr Soc. 2020 Feb 01;4(2):bvz026. Epub 2019-11-27.

PubMed abstract

Adult Life-Course Trajectories of Lung Function and the Development of Emphysema: The CARDIA Lung Study

Authors: Washko GR; Iribarren C; Kalhan R; et al.

Am J Med. 2020 02;133(2):222-230.e11. Epub 2019-07-29.

PubMed abstract

The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change

Authors: Oni-Orisan A; Haldar T; Ranatunga DK; Medina MW; Schaefer C; Krauss RM; Iribarren C; Risch N; Hoffmann TJ

NPJ Genom Med. 2020;5:1. Epub 2020-01-16.

PubMed abstract

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation

Authors: Kuang YL; Iribarren C; Medina MW; et al.

Stem Cell Res. 2019 05;37:101434. Epub 2019-04-10.

PubMed abstract

Closing the Evidence Gap in Interstitial Lung Disease: The Promise of Real World Data

Authors: Farrand E; Anstrom KJ; Bernard G; Butte AJ; Iribarren C; Ley B; Martinez FJ; Collard HR

Am J Respir Crit Care Med. 2019 05 01;199(9):1061-1065.

PubMed abstract

Large-scale, multi-ethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults

Authors: Dahlin A; Iribarren C; Wu AC; et al.

J Allergy Clin Immunol Pract. 2020 05;8(5):1475-1476. Epub 2020-04-06.

PubMed abstract

Kidney function, proteinuria and breast arterial calcification in women without clinical cardiovascular disease: The MINERVA study

Authors: Parikh RV; Iribarren C; Lee C; Levine-Hall T; Tan TC; Sanchez G; Ding H; Bidgoli FA; Molloi S; Go AS

PLoS ONE. 2019;14(1):e0210973. Epub 2019-01-17.

PubMed abstract

Inflammation and Endothelial Activation in Early Adulthood are Associated with Future Emphysema: The CARDIA Lung Study

Authors: Wells JM; Colangelo LA; Sivarajan L; Thyagarajan B; Dransfield MT; Iribarren C; Reyfman PA; Jacobs DR; Washko GR; Kalhan R

Eur Respir J. 2019 01;53(1). Epub 2019-01-17.

PubMed abstract

Association of Breast Arterial Calcification Presence and Gradation with the Ankle-Brachial Index among Postmenopausal Women

Authors: Iribarren C; Sanchez G; Lu M; Bidgoli FA; Cho HM; Ding H; Molloi S

Eur J Cardiovasc Med. 2018 Nov;5(5):544-551. Epub 2018-11-16.

PubMed abstract

A functional splicing variant associated with decreased asthma risk abolishes the ability of gasdermin B (GSMDB) to induce epithelial cell pyroptosis

Authors: Panganiban RA; Iribarren C; Lu Q; et al.

J Allergy Clin Immunol. 2018 11;142(5):1469-1478.e2. Epub 2018-01-09.

PubMed abstract

Characterization of Statin Low-Density Lipoprotein Cholesterol Dose-Response Using Electronic Health Records in a Large Population-Based Cohort

Authors: Oni-Orisan A; Hoffmann TJ; Ranatunga D; Medina MW; Jorgenson E; Schaefer C; Krauss RM; Iribarren C; Risch N

Circ Genom Precis Med. 2018 Sep;11(9):e002043.

PubMed abstract

Seasonal patterns of Asthma medication fills among diverse populations of the United States

Authors: Turi KN; Iribarren C; Wu P; et al.

J Asthma. 2018 07;55(7):764-770. Epub 2017-09-07.

PubMed abstract

Respiratory Symptoms in Young Adults and Future Lung Disease: The CARDIA Lung Study

Authors: Kalhan R; Iribarren C; Washko GR; et al.

Am J Respir Crit Care Med. 2018 06 15;197(12):1616-1624.

PubMed abstract

Weighted Multi-marker Genetic Risk Scores for Incident Coronary Heart Disease among Individuals of African, Latino and East-Asian Ancestry

Authors: Iribarren C; Lu M; Jorgenson E; Martínez M; Lluis-Ganella C; Subirana I; Salas E; Elosua R

Sci Rep. 2018 05 01;8(1):6853. Epub 2018-05-01.

PubMed abstract

A large electronic-health-record-based genome-wide study of serum lipids

Authors: Hoffmann TJ; Schaefer C; Iribarren C; Risch N; et al.

Nat Genet. 2018 03;50(3):401-413. Epub 2018-03-05.

PubMed abstract

MultIethNic Study of BrEast ARterial Calcium Gradation and CardioVAscular Disease: cohort recruitment and baseline characteristics

Authors: Iribarren C; Quesenberry C; Molloi S; et al.

Ann Epidemiol. 2018 01;28(1):41-47.e12. Epub 2017-12-05.

PubMed abstract

Trends in health care utilization for asthma exacerbations among diverse populations with asthma in the United States

Authors: Stone C; Iribarren C; Wu P; et al.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):295-297.e5. Epub 2017-09-19.

PubMed abstract

Cohort Study of ECG Left Ventricular Hypertrophy Trajectories: Ethnic Disparities, Associations With Cardiovascular Outcomes, and Clinical Utility

Authors: Iribarren C; Round AD; Lu M; Okin PM; McNulty EJ

J Am Heart Assoc. 2017 Oct 05;6(10). Epub 2017-10-05.

PubMed abstract

Code-Based Diagnostic Algorithms for Idiopathic Pulmonary Fibrosis: Case Validation and Improvement

Authors: Ley B; Urbania T; Husson G; Vittinghoff E; Brush DR; Eisner MD; Iribarren C; Collard HR

Ann Am Thorac Soc. 2017 Jun;14(6):880-887.

PubMed abstract

Detecting Cardiovascular Disease from Mammograms With Deep Learning

Authors: Wang J; Ding H; Bidgoli FA; Zhou B; Iribarren C; Molloi S; Baldi P

IEEE Trans Med Imaging. 2017 05;36(5):1172-1181. Epub 2017-01-19.

PubMed abstract

Cardiovascular and cerebrovascular events among patients receiving omalizumab: Pooled analysis of patient-level data from 25 randomized, double-blind, placebo-controlled clinical trials

Authors: Iribarren C; Rothman KJ; Bradley MS; Carrigan G; Eisner MD; Chen H

J Allergy Clin Immunol. 2017 05;139(5):1678-1680. Epub 2017-01-17.

PubMed abstract

Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study of moderate-to-severe asthma

Authors: Iribarren C; Rahmaoui A; Long AA; Szefler SJ; Bradley MS; Carrigan G; Eisner MD; Chen H; Omachi TA; Farkouh ME; Rothman KJ

J Allergy Clin Immunol. 2017 May;139(5):1489-1495.e5. Epub 2016-09-14.

PubMed abstract

Television viewing and hostile personality trait increase the risk of injuries

Authors: Fabio A; Chen CY; Dearwater S; Jacobs DR; Erickson D; Matthews KA; Iribarren C; Sidney S; Pereira MA

Int J Inj Contr Saf Promot. 2017 Mar;24(1):44-53. Epub 2015-08-14.

PubMed abstract

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation

Authors: Hoffmann TJ; Ehret GB; Nandakumar P; Ranatunga D; Schaefer C; Kwok PY; Iribarren C; Chakravarti A; Risch N

Nat Genet. 2017 Jan;49(1):54-64. Epub 2016-11-14.

PubMed abstract

Clinical Utility of Multi-marker Genetic Risk Scores for Prediction of Incident Coronary Heart Disease: A Cohort Study among over 51 Thousand Individuals of European Ancestry

Authors: Iribarren C; Lu M; Jorgenson E; Martínez M; Lluis-Ganella C; Subirana I; Salas E; Elosua R

Circ Cardiovasc Genet. 2016 Dec;9(6):531-540. Epub 2016-10-25.

PubMed abstract

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

Authors: Loley C; Iribarren C; König IR; et al.

Sci Rep. 2016 10 12;6:35278. Epub 2016-10-12.

PubMed abstract

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Authors: Ehret GB; Iribarren C; Munroe PB; et al.

Nat Genet. 2016 Oct;48(10):1171-84. Epub 2016-09-12.

PubMed abstract

High-sensitivity cardiac troponin I and incident coronary heart disease among asymptomatic older adults

Authors: Iribarren C; Chandra M; Rana JS; Hlatky MA; Fortmann SP; Quertermous T; Go AS

Heart. 2016 Aug 01;102(15):1177-82. Epub 2016-03-30.

PubMed abstract

Obesity and Functioning Among Individuals with Chronic Obstructive Pulmonary Disease (COPD)

Authors: Katz P; Iribarren C; Sanchez G; Blanc PD

COPD. 2016 Jun;13(3):352-9. Epub 2015-12-18.

PubMed abstract

Intake of fish and long-chain omega-3 polyunsaturated fatty acids and incidence of metabolic syndrome among American young adults: a 25-year follow-up study

Authors: Kim YS; Xun P; Iribarren C; Van Horn L; Steffen L; Daviglus ML; Siscovick D; Liu K; He K

Eur J Nutr. 2016 Jun;55(4):1707-16. Epub 2016-01-27.

PubMed abstract

Susceptibility Loci for Clinical CAD and Subclinical Coronary Atherosclerosis Throughout the Life-Course

Authors: Salfati E; Nandkeolyar S; Fortmann SP; Sidney S; Hlatky MA; Quertermous T; Go AS; Iribarren C; Herrington DM; Goldstein BA; Assimes TL

Circ Cardiovasc Genet. 2015 Dec;8(6):803-11. Epub 2015-09-28.

PubMed abstract

Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

Authors: Banda Y; Croen LA; Iribarren C; Kushi LH; Quesenberry CP; Sakoda LC; Van Den Eeden SK; Whitmer RA; Schaefer C; Risch N; et al.

Genetics. 2015 Aug;200(4):1285-95. Epub 2015-06-19.

PubMed abstract

Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

Authors: Kvale MN; Croen LA; Iribarren C; Kushi LH; Quesenberry CP; Sakoda LC; Van Den Eeden SK; Whitmer RA; Schaefer C; Risch N; et al.

Genetics. 2015 Aug;200(4):1051-60. Epub 2015-06-19.

PubMed abstract

Incidence of malignancy in patients with moderate-to-severe asthma treated with or without omalizumab(?)

Authors: Long A; Rahmaoui A; Rothman KJ; Guinan E; Eisner M; Bradley MS; Iribarren C; Chen H; Carrigan G; Rosén K; Szefler SJ

J Allergy Clin Immunol. 2014 Sep;134(3):560-567.e4. Epub 2014-03-27.

PubMed abstract

Short QT in a Cohort of 1.7 Million Persons: Prevalence, Correlates, and Prognosis

Authors: Iribarren C; Round AD; Peng JA; Lu M; Klatsky AL; Zaroff JG; Holve TJ; Prasad A; Stang P

Ann Noninvasive Electrocardiol. 2014 Sep;19(5):490-500. Epub 2014-05-14.

PubMed abstract

Hostility Modifies the Association between TV Viewing and Cardiometabolic Risk

Authors: Fabio A; Chen CY; Kim KH; Erickson D; Jacobs DR; Zgibor JC; Chung T; Matthews KA; Sidney S; Iribarren C; Pereira MA

J Obes. 2014;2014:784594. Epub 2014-06-23.

PubMed abstract

Common variants associated with plasma triglycerides and risk for coronary artery disease

Authors: Do R; Iribarren C; Kathiresan S; et al.

Nat Genet. 2013 Nov;45(11):1345-52. Epub 2013-10-06.

PubMed abstract

Validation of a population-based method to assess drug-induced alterations in the QT interval: a self-controlled crossover study

Authors: Iribarren C; Round AD; Peng JA; Lu M; Zaroff JG; Holve TJ; Prasad A; Stang P

Pharmacoepidemiol Drug Saf. 2013 Nov;22(11):1222-32. Epub 2013-07-16.

PubMed abstract

Discovery and refinement of loci associated with lipid levels

Authors: Global Lipids Genetics Consortium; Iribarren C; Abecasis GR; et al.

Nat Genet. 2013 Nov;45(11):1274-83. Epub 2013-10-06.

PubMed abstract

African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women’s Health Initiative

Authors: Perez MV; Hoffmann TJ; Tang H; Thornton T; Stefanick ML; Larson JC; Kooperberg C; Reiner AP; Caan B; Iribarren C; Risch N

Am Heart J. 2013 Sep;166(3):566-72.

PubMed abstract

Risk Adjustment for Health Care Financing in Chronic Disease: What Are We Missing By Failing to Account for Disease Severity?

Authors: Omachi TA; Gregorich SE; Eisner MD; Penaloza RA; Tolstykh IV; Yelin EH; Iribarren C; Dudley RA; Blanc PD

Med Care. 2013 Aug;51(8):740-7.

PubMed abstract

Oral Contraceptive Use and the ECG: Evidence of an Adverse QT Effect on Corrected QT Interval

Authors: Sedlak T; Shufelt C; Iribarren C; Lyon LL; Bairey Merz CN

Ann Noninvasive Electrocardiol. 2013 Jul;18(4):389-98. Epub 2013-05-03.

PubMed abstract

Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

Authors: Randall JC; Iribarren C; Schlessinger D; et al.

PLoS Genet. 2013 Jun;9(6):e1003500. Epub 2013 Jun 6.

PubMed abstract

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Authors: den Hoed M; Eijgelsheim M; Esko T; Brundel BJ; Peal DS; Evans DM; Nolte IM; Segre AV; Holm H; Handsaker RE; Westra HJ; Johnson T; Isaacs A; Yang J; Lundby A; Zhao JH; Kim YJ; Go MJ; Almgren P; Bochud M; Boucher G; Cornelis MC; Gudbjartsson D; Hadley D; van der Harst P; Hayward C; den Heijer M; Igl W; Jackson AU; Kutalik Z; Luan J; Kemp JP; Kristiansson K; Ladenvall C; Lorentzon M; Montasser ME; Njajou OT; O'Reilly PF; Padmanabhan S; St Pourcain B; Rankinen T; Salo P; Tanaka T; Timpson NJ; Vitart V; Waite L; Wheeler W; Zhang W; Draisma HH; Feitosa MF; Kerr KF; Lind PA; Mihailov E; Onland-Moret NC; Song C; Weedon MN; Xie W; Yengo L; Absher D; Albert CM; Alonso A; Arking DE; de Bakker PI; Balkau B; Barlassina C; Benaglio P; Bis JC; Bouatia-Naji N; Brage S; Chanock SJ; Chines PS; Chung M; Darbar D; Dina C; Dorr M; Elliott P; Felix SB; Fischer K; Fuchsberger C; de Geus EJ; Goyette P; Gudnason V; Harris TB; Hartikainen AL; Havulinna AS; Heckbert SR; Hicks AA; Hofman A; Holewijn S; Hoogstra-Berends F; Hottenga JJ; Jensen MK; Johansson A; Junttila J; Kaab S; Kanon B; Ketkar S; Khaw KT; Knowles JW; Kooner AS; Kors JA; Kumari M; Milani L; Laiho P; Lakatta EG; Langenberg C; Leusink M; Liu Y; Luben RN; Lunetta KL; Lynch SN; Markus MR; Marques-Vidal P; Mateo Leach I; McArdle WL; McCarroll SA; Medland SE; Miller KA; Montgomery GW; Morrison AC; Muller-Nurasyid M; Navarro P; Nelis M; O'Connell JR; O'Donnell CJ; Ong KK; Newman AB; Peters A; Polasek O; Pouta A; Pramstaller PP; Psaty BM; Rao DC; Ring SM; Rossin EJ; Rudan D; Sanna S; Scott RA; Sehmi JS; Sharp S; Shin JT; Singleton AB; Smith AV; Soranzo N; Spector TD; Stewart C; Stringham HM; Tarasov KV; Uitterlinden AG; Vandenput L; Hwang SJ; Whitfield JB; Wijmenga C; Wild SH; Willemsen G; Wilson JF; Witteman JC; Wong A; Wong Q; Jamshidi Y; Zitting P; Boer JM; Boomsma DI; Borecki IB; van Duijn CM; Ekelund U; Forouhi NG; Froguel P; Hingorani A; Ingelsson E; Kivimaki M; Kronmal RA; Kuh D; Lind L; Martin NG; Oostra BA; Pedersen NL; Quertermous T; Rotter JI; van der Schouw YT; Verschuren WM; Walker M; Albanes D; Arnar DO; Assimes TL; Bandinelli S; Boehnke M; de Boer RA; Bouchard C; Caulfield WL; Chambers JC; Curhan G; Cusi D; Eriksson J; Ferrucci L; van Gilst WH; Glorioso N; de Graaf J; Groop L; Gyllensten U; Hsueh WC; Hu FB; Huikuri HV; Hunter DJ; Iribarren C; Isomaa B; Jarvelin MR; Jula A; Kahonen M; Kiemeney LA; Van der Klauw MM; Kooner JS; Kraft P; Iacoviello L; Lehtimaki T; Lokki ML; Mitchell BD; Navis G; Nieminen MS; Ohlsson C; Poulter NR; Qi L; Raitakari OT; Rimm EB; Rioux JD; Rizzi F; Rudan I; Salomaa V; Sever PS; Shields DC; Shuldiner AR; Sinisalo J; Stanton AV; Stolk RP; Strachan DP; Tardif JC; Thorsteinsdottir U; Tuomilehto J; van Veldhuisen DJ; Virtamo J; Viikari J; Vollenweider P; Waeber G; Widen E; Cho YS; Olsen JV; Visscher PM; Willer C; Franke L; Global BPgen Consortium; CARDIoGRAM Consortium; Erdmann J; Thompson JR; PR GWAS Consortium; Pfeufer A

Nat Genet. 2013 Jun;45(6):621-31. Epub 2013 Apr 14.

PubMed abstract

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Authors: Berndt SI; Iribarren C; Ingelsson E; et al.

Nat Genet. 2013 May;45(5):501-12. Epub 2013 Apr 7.

PubMed abstract

Breast Arterial Calcification: a New Marker of Cardiovascular Risk?

Authors: Iribarren C; Molloi S

Curr Cardiovasc Risk Rep. 2013 Apr;7(2):126-135. Epub 2013-02-03.

PubMed abstract

Both Pulmonary and Extra-Pulmonary Factors Predict the Development of Disability in Chronic Obstructive Pulmonary Disease

Authors: Singer JP; Katz PP; Iribarren C; Omachi TA; Sanchez G; Yelin EH; Cisternas MG; Blanc PD

Respiration. 2013;85(5):375-83. Epub 2012 Jun 9.

PubMed abstract

Large-scale association analysis identifies new risk loci for coronary artery disease

Authors: CARDIoGRAMplusC4D Consortium; Deloukas P; Kanoni S; Willenborg C; Farrall M; Assimes TL; Thompson JR; Ingelsson E; Saleheen D; Erdmann J; Goldstein BA; Stirrups K; Konig IR; Cazier JB; Johansson A; Hall AS; Lee JY; Willer CJ; Chambers JC; Esko T; Folkersen L; Goel A; Grundberg E; Havulinna AS; Ho WK; Hopewell JC; Eriksson N; Kleber ME; Kristiansson K; Lundmark P; Lyytikainen LP; Rafelt S; Shungin D; Strawbridge RJ; Thorleifsson G; Tikkanen E; Van Zuydam N; Voight BF; Waite LL; Zhang W; Ziegler A; Absher D; Altshuler D; Balmforth AJ; Barroso I; Braund PS; Burgdorf C; Claudi-Boehm S; Cox D; Dimitriou M; Do R; DIAGRAM Consortium; CARDIOGENICS Consortium; Doney AS; El Mokhtari N; Eriksson P; Fischer K; Fontanillas P; Franco-Cereceda A; Gigante B; Groop L; Gustafsson S; Hager J; Hallmans G; Han BG; Hunt SE; Kang HM; Illig T; Kessler T; Knowles JW; Kolovou G; Kuusisto J; Langenberg C; Langford C; Leander K; Lokki ML; Lundmark A; McCarthy MI; Meisinger C; Melander O; Mihailov E; Maouche S; Morris AD; Muller-Nurasyid M; MuTHER Consortium; Nikus K; Peden JF; Rayner NW; Rasheed A; Rosinger S; Rubin D; Rumpf MP; Schafer A; Sivananthan M; Song C; Stewart AF; Tan ST; Thorgeirsson G; van der Schoot CE; Wagner PJ; Wellcome Trust Case Control Consortium; Wells GA; Wild PS; Yang TP; Amouyel P; Arveiler D; Basart H; Boehnke M; Boerwinkle E; Brambilla P; Cambien F; Cupples AL; de Faire U; Dehghan A; Diemert P; Epstein SE; Evans A; Ferrario MM; Ferrieres J; Gauguier D; Go AS; Goodall AH; Gudnason V; Hazen SL; Holm H; Iribarren C; Jang Y; Kahonen M; Kee F; Kim HS; Klopp N; Koenig W; Kratzer W; Kuulasmaa K; Laakso M; Laaksonen R; Lee JY; Lind L; Ouwehand WH; Parish S; Park JE; Pedersen NL; Peters A; Quertermous T; Rader DJ; Salomaa V; Schadt E; Shah SH; Sinisalo J; Stark K; Stefansson K; Tregouet DA; Virtamo J; Wallentin L; Wareham N; Zimmermann ME; Nieminen MS; Hengstenberg C; Sandhu MS; Pastinen T; Syvanen AC; Hovingh GK; Dedoussis G; Franks PW; Lehtimaki T; Metspalu A; Zalloua PA; Siegbahn A; Schreiber S; Ripatti S; Blankenberg SS; Perola M; Clarke R; Boehm BO; O'Donnell C; Reilly MP; Marz W; Collins R; Kathiresan S; Hamsten A; Kooner JS; Thorsteinsdottir U; Danesh J; Palmer CN; Roberts R; Watkins H; Schunkert H; Samani NJ

Nat Genet. 2013 Jan;45(1):25-33. Epub 2012 Dec 2.

PubMed abstract

Intakes of long-chain omega-3 (n-3) PUFAs and fish in relation to incidence of asthma among American young adults: the CARDIA study

Authors: Li J; Xun P; Zamora D; Sood A; Liu K; Daviglus M; Iribarren C; Jacobs D Jr; Shikany JM; He K

Am J Clin Nutr. 2013 Jan;97(1):173-8. Epub 2012 Nov 28.

PubMed abstract

Adult asthma and risk of coronary heart disease, cerebrovascular disease, and heart failure: a prospective study of 2 matched cohorts

Authors: Iribarren C; Tolstykh IV; Miller MK; Sobel E; Eisner MD

Am J Epidemiol. 2012 Dec 1;176(11):1014-24. Epub 2012 Nov 8.

PubMed abstract

FTO genotype is associated with phenotypic variability of body mass index

Authors: Yang J; Iribarren C; Zillikens MC; et al.

Nature. 2012 Oct 11;490(7419):267-72. Epub 2012 Sep 16.

PubMed abstract

Sex Hormones and the QT Interval: A Review

Authors: Sedlak T; Shufelt C; Iribarren C; Merz CN

J Womens Health (Larchmt). 2012 Sep;21(9):933-41. Epub 2012 Jun 4.

PubMed abstract

Relationship of obesity with respiratory symptoms and decreased functional capacity in adults without established COPD

Authors: Zutler M; Singer JP; Omachi TA; Eisner M; Iribarren C; Katz P; Blanc PD

Prim Care Respir J. 2012 Jun;21(2):194-201.

PubMed abstract

Age-related somatic structural changes in the nuclear genome of human blood cells

Authors: Forsberg LA; Iribarren C; Dumanski JP; et al.

Am J Hum Genet. 2012 Feb 10;90(2):217-28. Epub 2012 Feb 2.

PubMed abstract

Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm

Authors: Hoffmann TJ; Iribarren C; Quesenberry C; Van den Eeden SK; Whitmer RA; Schaefer C; Risch N; et al.

Genomics. 2011 Dec;98(6):422-30. Epub 2011 Aug 28.

PubMed abstract

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Authors: International Consortium for Blood Pressure Genome-Wide Association Studies; Galan P; Guarrera S; Rice KM; Bergman R; et al.

Nature. 2011 Sep 11;478(7367):103-9.

PubMed abstract

Chronic kidney disease and risk for presenting with acute myocardial infarction versus stable exertional angina in adults with coronary heart disease

Authors: Go AS; Bansal N; Chandra M; Lathon PV; Fortmann SP; Iribarren C; Hsu CY; Hlatky MA; ADVANCE Study Investigators

J Am Coll Cardiol. 2011 Oct 4;58(15):1600-7.

PubMed abstract

Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array

Authors: Hoffmann TJ; Iribarren C; Quesenberry C; Van den Eeden SK; Whitmer RA; Schaefer C; Risch N; et al.

Genomics. 2011 Aug;98(2):79-89. Epub 2011 Apr 30.

PubMed abstract

Ethnicity and risk of hospitalization for asthma and chronic obstructive pulmonary disease

Authors: Tran HN; Siu S; Iribarren C; Udaltsova N; Klatsky AL

Ann Epidemiol. 2011 Aug;21(8):615-22. Epub 2011 Mar 17.

PubMed abstract

Physical activity in older subjects is associated with increased coronary vasodilation: the ADVANCE study

Authors: Nguyen PK; Terashima M; Fair JM; Varady A; Taylor-Piliae RE; Iribarren C; Go AS; Haskell WL; Hlatky MA; Fortmann SP; McConnell MV

JACC Cardiovasc Imaging. 2011 Jun;4(6):622-9.

PubMed abstract

Ankle brachial index screening in asymptomatic older adults

Authors: Taylor-Piliae RE; Fair JM; Varady AN; Hlatky MA; Norton LC; Iribarren C; Go AS; Fortmann SP

Am Heart J. 2011 May;161(5):979-85.

PubMed abstract

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

Authors: Kraja AT; Iribarren C; Borecki IB; et al.

Diabetes. 2011 Apr;60(4):1329-39. Epub 2011 Mar 8.

PubMed abstract

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Authors: Schunkert H; Iribarren C; Samani NJ; et al.

Nat Genet. 2011 Mar 6;43(4):333-8.

PubMed abstract

Respiratory and skeletal muscle strength in chronic obstructive pulmonary disease: impact on exercise capacity and lower extremity function

Authors: Singer J; Yelin EH; Katz PP; Sanchez G; Iribarren C; Eisner MD; Blanc PD

J Cardiopulm Rehabil Prev. 2011 Mar-Apr;31(2):111-9.

PubMed abstract

Development of disability in chronic obstructive pulmonary disease: beyond lung function

Authors: Eisner MD; Iribarren C; Blanc PD; Yelin EH; Ackerson L; Byl N; Omachi TA; Sidney S; Katz PP

Thorax. 2011 Feb;66(2):108-14. Epub 2010 Nov 3.

PubMed abstract

Circulating angiopoietins-1 and -2, angiopoietin receptor Tie-2 and vascular endothelial growth factor-A as biomarkers of acute myocardial infarction: a prospective nested case-control study

Authors: Iribarren C; Phelps BH; Darbinian JA; McCluskey ER; Quesenberry CP; Hytopoulos E; Vogelman JH; Orentreich N

BMC Cardiovasc Disord. 2011 Jun 14;11:31.

PubMed abstract

Potential role of differential medication use in explaining excess risk of cardiovascular events and death associated with chronic kidney disease: A cohort study

Authors: Bansal N; Hsu CY; Chandra M; Iribarren C; Fortmann SP; Hlatky MA; Go AS

BMC Nephrol. 2011 Sep 14;12:44.

PubMed abstract

Racial variation in lipoprotein-associated phospholipase A in older adults

Authors: Lee KK; Fortmann SP; Varady A; Fair JM; Go AS; Quertermous T; Hlatky MA; Iribarren C

BMC Cardiovasc Disord. 2011 Jun 29;11:38.

PubMed abstract

Socioeconomic status, race and COPD health outcomes

Authors: Eisner MD; Blanc PD; Omachi TA; Yelin EH; Sidney S; Katz PP; Ackerson LM; Sanchez G; Tolstykh I; Iribarren C

J Epidemiol Community Health. 2011 Jan;65(1):26-34. Epub 2009 Oct 23.

PubMed abstract

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

Authors: Assimes TL; Iribarren C; Go A; Cardiogenics; et al.

J Am Coll Cardiol. 2010 Nov 2;56(19):1552-63.

PubMed abstract

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Authors: Speliotes EK; Iribarren C; Procardis Consortium; et al.

Nat Genet. 2010 Nov;42(11):937-48. Epub 2010 Oct 10.

PubMed abstract

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Authors: Heid IM; Iribarren C; MAGIC; et al.

Nat Genet. 2010 Nov;42(11):949-60. Epub 2010 Oct 10.

PubMed abstract

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Authors: Lango Allen H; Iribarren C; Hirschhorn JN; et al.

Nature. 2010 Oct 14;467(7317):832-8. Epub 2010 Sep 29.

PubMed abstract

Prevalence of electrocardiographic abnormalities in a middle-aged, biracial population: Coronary Artery Risk Development in Young Adults study

Authors: Walsh JA 3rd; Prineas R; Daviglus ML; Ning H; Liu K; Lewis CE; Sidney S; Schreiner PJ; Iribarren C; Lloyd-Jones DM

J Electrocardiol. 2010 Sep-Oct;43(5):385.e1-9. Epub 2010 Apr 5.

PubMed abstract

An ‘almost exhaustive’ search-based sequential permutation method for detecting epistasis in disease association studies

Authors: Ma L; Assimes TL; Asadi NB; Iribarren C; Quertermous T; Wong WH

Genet Epidemiol. 2010 Jul;34(5):434-43.

PubMed abstract

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

Authors: Tobacco and Genetics Consortium

Nat Genet. 2010 May;42(5):441-7. Epub 2010 Apr 25.

PubMed abstract

Asthma and the prospective risk of anaphylactic shock and other allergy diagnoses in a large integrated health care delivery system

Authors: Iribarren C; Tolstykh IV; Miller MK; Eisner MD

Ann Allergy Asthma Immunol. 2010 May;104(5):371-7.

PubMed abstract

The COPD Helplessness Index: a new tool to measure factors affecting patient self-management

Authors: Omachi TA; Katz PP; Yelin EH; Iribarren C; Knight SJ; Blanc PD; Eisner MD

Chest. 2010 Apr;137(4):823-30. Epub 2009 Oct 16.

PubMed abstract

Measurement of COPD severity using a survey-based score: validation in a clinically and physiologically characterized cohort

Authors: Eisner MD; Omachi TA; Katz PP; Yelin EH; Iribarren C; Blanc PD

Chest. 2010 Apr;137(4):846-51. Epub 2009 Dec 29.

PubMed abstract

Influence of anxiety on health outcomes in COPD

Authors: Eisner MD; Blanc PD; Yelin EH; Katz PP; Sanchez G; Iribarren C; Omachi TA

Thorax. 2010 Mar;65(3):229-34.

PubMed abstract

Validation of the Stanford Brief Activity Survey: examining psychological factors and physical activity levels in older adults

Authors: Taylor-Piliae RE; Fair JM; Haskell WL; Varady AN; Iribarren C; Hlatky MA; Go AS; Fortmann SP

J Phys Act Health. 2010 Jan;7(1):87-94.

PubMed abstract

Distribution of asymmetric dimethylarginine among 980 healthy, older adults of different ethnicities

Authors: Sydow K; Fortmann SP; Fair JM; Varady A; Hlatky MA; Go AS; Iribarren C; Tsao PS; ADVANCE Investigators

Clin Chem. 2010 Jan;56(1):111-20. Epub 2009 Nov 5.

PubMed abstract

COPD and cognitive impairment: the role of hypoxemia and oxygen therapy

Authors: Thakur N; Blanc PD; Julian LJ; Yelin EH; Katz PP; Sidney S; Iribarren C; Eisner MD

Int J Chron Obstruct Pulmon Dis. 2010 Sep 7;5:263-9.

PubMed abstract

Alcohol and lung airways function

Authors: Siu ST; Udaltsova N; Iribarren C; Klatsky AL

Perm J. 2010 Spring;14(1):11-8.

PubMed abstract

Lipoprotein-associated phospholipase A2 and C-reactive protein for measurement of inflammatory risk: Independent or complementary?

Authors: Iribarren C

Curr Cardiovasc Risk Rep. 2010;4(1):57-67.

Right coronary wall CMR in the older asymptomatic advance cohort: positive remodeling and associations with type 2 diabetes and coronary calcium

Authors: Terashima M; Iribarren C; Go AS; McConnell MV; et al.

J Cardiovasc Magn Reson. 2010 Dec 30;12:75.

PubMed abstract

Passive smoke exposure and circulating carotenoids in the CARDIA study

Authors: Widome R; Jacobs DR Jr; Hozawa A; Sijtsma F; Gross M; Schreiner PJ; Iribarren C

Ann Nutr Metab. 2010;56(2):113-8. Epub 2010 Jan 29.

PubMed abstract

The dilemma of incidental findings on cardiac computed tomography

Authors: Hlatky MA; Iribarren C

J Am Coll Cardiol. 2009 Oct 13;54(16):1542-3.

PubMed abstract

Physical fitness and carotid atherosclerosis in men

Authors: Lee CD; Jae SY; Iribarren C; Pettee KK; Choi YH

Int J Sports Med. 2009 Sep;30(9):672-6. Epub 2009 Jun 30.

PubMed abstract

Depression and health-related quality of life in chronic obstructive pulmonary disease

Authors: Omachi TA; Katz PP; Yelin EH; Gregorich SE; Iribarren C; Blanc PD; Eisner MD

Am J Med. 2009 Aug;122(8):778.e9-15.

PubMed abstract

Insulin resistance independently predicts the progression of coronary artery calcification

Authors: Lee KK; Fortmann SP; Fair JM; Iribarren C; Rubin GD; Varady A; Go AS; Quertermous T; Hlatky MA

Am Heart J. 2009 May;157(5):939-45.

PubMed abstract

Reproducibility of breast arterial calcium mass quantification using digital mammography

Authors: Molloi S; Mehraien T; Iribarren C; Smith C; Ducote JL; Feig SA

Acad Radiol. 2009 Mar;16(3):275-82.

PubMed abstract

Cardiorespiratory fitness and coronary artery calcification in young adults: The CARDIA Study

Authors: Lee CD; Jacobs DR Jr; Hankinson A; Iribarren C; Sidney S

Atherosclerosis. 2009 Mar;203(1):263-8. Epub 2008 Jun 22.

PubMed abstract

Risk factors for end-stage renal disease: 25-year follow-up

Authors: Hsu CY; Iribarren C; McCulloch CE; Darbinian J; Go AS

Arch Intern Med. 2009 Feb 23;169(4):342-50.

PubMed abstract

Birthplace and mortality among insured Latinos: the paradox revisited

Authors: Iribarren C; Darbinian JA; Fireman BH; Burchard EG

Ethn Dis. 2009 Spring;19(2):185-91.

PubMed abstract

Characterizing the admixed African ancestry of African Americans

Authors: Zakharia F; Go AS; Iribarren C; Risch N; Tang H; et al.

Genome Biol. 2009;10(12):R141. Epub 2009 Dec 22.

PubMed abstract

Peroxisome proliferator-activated receptor gamma polymorphisms and coronary heart disease

Authors: Dallongeville J; Iribarren C; Go AS; Meirhaeghe A; et al.

PPAR Res. 2009;2009:543746. Epub 2009 Dec 1.

PubMed abstract

Occupational exposures and the risk of COPD: dusty trades revisited

Authors: Blanc PD; Iribarren C; Trupin L; Earnest G; Katz PP; Balmes J; Sidney S; Eisner MD

Thorax. 2009 Jan;64(1):6-12. Epub 2008 Aug 4.

PubMed abstract

The impact of SHS exposure on health status and exacerbations among patients with COPD

Authors: Eisner MD; Iribarren C; Yelin EH; Sidney S; Katz PP; Sanchez G; Blanc PD

Int J Chron Obstruct Pulmon Dis. 2009;4:169-76. Epub 2009 May 7.

PubMed abstract

Incidental pulmonary nodules on cardiac computed tomography: prognosis and use

Authors: Iribarren C; Hlatky MA; Chandra M; Fair JM; Rubin GD; Go AS; Burt JR; Fortmann SP

Am J Med. 2008 Nov;121(11):989-96.

PubMed abstract

COPD as a systemic disease: impact on physical functional limitations

Authors: Eisner MD; Blanc PD; Yelin EH; Sidney S; Katz PP; Ackerson L; Lathon P; Tolstykh I; Omachi T; Byl N; Iribarren C

Am J Med. 2008 Sep;121(9):789-96.

PubMed abstract

Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study

Authors: Assimes TL; Iribarren C; Go AS; Risch N; Quertermous T; et al.

Hum Mol Genet. 2008 Aug 1;17(15):2320-8. Epub 2008 Apr 28.

PubMed abstract

Risk factors for death in adults with severe asthma

Authors: Omachi TA; Iribarren C; Sarkar U; Tolstykh I; Yelin EH; Katz PP; Blanc PD; Eisner MD

Ann Allergy Asthma Immunol. 2008 Aug;101(2):130-6.

PubMed abstract

Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation

Authors: Reiner AP; Walston JD; Jarvik GP; et al.

Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1407-12. Epub 2008 May 1.

PubMed abstract

Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease

Authors: Assimes TL; Knowles JW; Priest JR; Basu A; Volcik KA; Southwick A; Tabor HK; Hartiala J; Allayee H; Grove ML; Tabibiazar R; Sidney S; Fortmann SP; Go A; Hlatky M; Iribarren C; Boerwinkle E; Myers R; Risch N; Quertermous T

Hum Genet. 2008 May;123(4):399-408. Epub 2008 Mar 28.

PubMed abstract

A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease

Authors: Assimes TL; Go AS; Iribarren C; Risch N; Quertermous T; et al.

Atherosclerosis. 2008 May;198(1):136-44. Epub 2007 Oct 23.

PubMed abstract

Pulmonary function and the risk of functional limitation in chronic obstructive pulmonary disease

Authors: Eisner MD; Iribarren C; Yelin EH; Sidney S; Katz PP; Ackerson L; Lathon P; Tolstykh I; Omachi T; Byl N; Blanc PD

Am J Epidemiol. 2008 May 1;167(9):1090-101. Epub 2008 Mar 14.

PubMed abstract

Incidental findings on cardiac multidetector row computed tomography among healthy older adults: prevalence and clinical correlates

Authors: Burt JR; Iribarren C; Fair JM; Norton LC; Mahbouba M; Rubin GD; Hlatky MA; Go AS; Fortmann SP; Atherosclerotic Disease VFaGEAS

Arch Intern Med. 2008 Apr 14;168(7):756-61.

PubMed abstract

Community-level social capital and recurrence of acute coronary syndrome

Authors: Scheffler RM; Brown TT; Syme L; Kawachi I; Tolstykh I; Iribarren C

Soc Sci Med. 2008 Apr;66(7):1603-13. Epub 2008 Jan 28.

PubMed abstract

Impaired coronary vasodilation by magnetic resonance angiography is associated with advanced coronary artery calcification

Authors: Terashima M; Nguyen PK; Rubin GD; Iribarren C; Courtney BK; Go AS; Fortmann SP; McConnell MV

JACC Cardiovasc Imaging. 2008 Mar;1(2):167-73.

PubMed abstract

Longitudinal association of serum carotenoids and tocopherols with hostility: the CARDIA Study

Authors: Ohira T; Hozawa A; Iribarren C; Daviglus ML; Matthews KA; Gross MD; Jacobs DR Jr

Am J Epidemiol. 2008 Jan 1;167(1):42-50. Epub 2007 Oct 10.

PubMed abstract

Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

Authors: Knowles JW; Go A; Iribarren C; Risch N; Quertermous T; et al.

BMC Med Genet. 2008 Apr 2;9:23.

PubMed abstract

Do plasma biomarkers of coagulation and fibrinolysis differ between patients who have experienced an acute myocardial infarction versus stable exertional angina?

Authors: Itakura H; Sobel BE; Boothroyd D; Leung LL; Iribarren C; Go AS; Fortmann SP; Quertermous T; Hlatky MA; Atherosclerotic Disease VFaGEAAS

Am Heart J. 2007 Dec;154(6):1059-64.

PubMed abstract

Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarction

Authors: Knowles JW; Wang H; Itakura H; Southwick A; Myers RM; Iribarren C; Fortmann SP; Go AS; Quertermous T; Hlatky MA

Am Heart J. 2007 Dec;154(6):1052-8.

PubMed abstract

Matrix metalloproteinase circulating levels, genetic polymorphisms, and susceptibility to acute myocardial infarction among patients with coronary artery disease

Authors: Hlatky MA; Ashley E; Quertermous T; Boothroyd DB; Ridker P; Southwick A; Myers RM; Iribarren C; Fortmann SP; Go AS; Atherosclerotic Disease VFaGEAS

Am Heart J. 2007 Dec;154(6):1043-51.

PubMed abstract

Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease

Authors: Hlatky MA; Iribarren C; Go AS; et al.

Am Heart J. 2007 Dec;154(6):1035-42. Epub 2007 Sep 18.

PubMed abstract

Circulating chemokines accurately identify individuals with clinically significant atherosclerotic heart disease

Authors: Ardigo D; Assimes TL; Fortmann SP; Go AS; Hlatky M; Hytopoulos E; Iribarren C; Tsao PS; Tabibiazar R; Quertermous T; ADVANCE Investigators

Physiol Genomics. 2007 Nov 14;31(3):402-9. Epub 2007 Aug 14.

PubMed abstract

Effect of race on asthma management and outcomes in a large, integrated managed care organization

Authors: Erickson SE; Iribarren C; Tolstykh IV; Blanc PD; Eisner MD

Arch Intern Med. 2007 Sep 24;167(17):1846-52.

PubMed abstract

Ethnic differences in coronary artery calcium in a healthy cohort aged 60 to 69 years

Authors: Fair JM; Kiazand A; Varady A; Mahbouba M; Norton L; Rubin GD; Iribarren C; Go AS; Hlatky MA; Fortmann SP

Am J Cardiol. 2007 Sep 15;100(6):981-5. Epub 2007 Jul 2.

PubMed abstract

Traditional and novel risk factors for clinically diagnosed abdominal aortic aneurysm: the Kaiser multiphasic health checkup cohort study

Authors: Iribarren C; Darbinian JA; Go AS; Fireman BH; Lee CD; Grey DP

Ann Epidemiol. 2007 Sep;17(9):669-78. Epub 2007 May 18.

PubMed abstract

The metabolic syndrome is no better than its components

Authors: Iribarren C

Minerva Cardioangiol. 2007 Aug;55(4):487-9.

PubMed abstract

Clinical utility of the Stanford brief activity survey in men and women with early-onset coronary artery disease

Authors: Taylor-Piliae RE; Haskell WL; Iribarren C; Norton LC; Mahbouba MH; Fair JM; Hlatky MA; Go AS; Fortmann SP

J Cardiopulm Rehabil Prev. 2007 Jul-Aug;27(4):227-32.

PubMed abstract

Abdominal obesity and coronary artery calcification in young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study

Authors: Lee CD; Jacobs DR Jr; Schreiner PJ; Iribarren C; Hankinson A

Am J Clin Nutr. 2007 Jul;86(1):48-54.

PubMed abstract

Genetic ancestry, population sub-structure, and cardiovascular disease-related traits among African-American participants in the CARDIA Study

Authors: Reiner AP; Carlson CS; Ziv E; Iribarren C; Jaquish CE; Nickerson DA

Hum Genet. 2007 Jun;121(5):565-75. Epub 2007 Mar 14.

PubMed abstract

Passive smoke exposure trends and workplace policy in the Coronary Artery Risk Development in Young Adults (CARDIA) study (1985-2001)

Authors: Widome R; Jacobs DR Jr; Schreiner PJ; Iribarren C

Prev Med. 2007 Jun;44(6):490-5. Epub 2007 Feb 23.

PubMed abstract

Asymmetric dimethyl-arginine and coronary artery calcification in young adults entering middle age: the CARDIA Study

Authors: Iribarren C; Husson G; Sydow K; Wang BY; Sidney S; Cooke JP

Eur J Cardiovasc Prev Rehabil. 2007 Apr;14(2):222-9.

PubMed abstract

Patients with vascular calcifications are at increased risk of cardiovascular events: implications for risk factor management and further research

Authors: Iribarren C

J Intern Med. 2007 Mar;261(3):235-7.

PubMed abstract

Plasma leptin levels and coronary artery calcification in older adults

Authors: Iribarren C; Husson G; Go AS; Lo JC; Fair JM; Rubin GD; Hlatky MA; Fortmann SP

J Clin Endocrinol Metab. 2007 Feb;92(2):729-32. Epub 2006 Dec 5.

PubMed abstract

Body composition and functional limitation in COPD

Authors: Eisner MD; Blanc PD; Sidney S; Yelin EH; Lathon PV; Katz PP; Tolstykh I; Ackerson L; Iribarren C

Respir Res. 2007 Jan 29;8:7.

PubMed abstract

The influence of cigarette smoking on adult asthma outcomes

Authors: Eisner MD; Iribarren C

Nicotine Tob Res. 2007 Jan;9(1):53-6.

PubMed abstract

Exploring secular trends in the likelihood of receiving treatment for end-stage renal disease

Authors: Hsu CY; Go AS; McCulloch CE; Darbinian J; Iribarren C

Clin J Am Soc Nephrol. 2007 Jan;2(1):81-8. Epub 2006 Nov 29.

PubMed abstract

Value of the sagittal abdominal diameter in coronary heart disease risk assessment: cohort study in a large, multiethnic population

Authors: Iribarren C; Darbinian JA; Lo JC; Fireman BH; Go AS

Am J Epidemiol. 2006 Dec 15;164(12):1150-9. Epub 2006 Oct 13.

PubMed abstract

Metabolic syndrome and early-onset coronary artery disease: is the whole greater than its parts?

Authors: Iribarren C; Go AS; Husson G; Sidney S; Fair JM; Quertermous T; Hlatky MA; Fortmann SP

J Am Coll Cardiol. 2006 Nov 7;48(9):1800-7. Epub 2006 Oct 17.

PubMed abstract

The influence of perceived control of asthma on health outcomes

Authors: Calfee CS; Katz PP; Yelin EH; Iribarren C; Eisner MD

Chest. 2006 Nov;130(5):1312-8.

PubMed abstract

Risk factors for work disability in severe adult asthma

Authors: Eisner MD; Yelin EH; Katz PP; Lactao G; Iribarren C; Blanc PD

Am J Med. 2006 Oct;119(10):884-91.

PubMed abstract

Validation of a new brief physical activity survey among men and women aged 60-69 years

Authors: Taylor-Piliae RE; Norton LC; Haskell WL; Mahbouda MH; Fair JM; Iribarren C; Hlatky MA; Go AS; Fortmann SP

Am J Epidemiol. 2006 Sep 15;164(6):598-606. Epub 2006 Jul 13.

PubMed abstract

Active and passive smoking and development of glucose intolerance among young adults in a prospective cohort: CARDIA study

Authors: Houston TK; Person SD; Pletcher MJ; Liu K; Iribarren C; Kiefe CI

BMJ. 2006 May 6;332(7549):1064-9. Epub 2006 Apr 7.

PubMed abstract

The association of cigarette smoking with self-reported disease before middle age: the Coronary Artery Risk Development in Young Adults (CARDIA) study

Authors: Hozawa A; Houston T; Steffes MW; Widome R; Williams OD; Iribarren C; Pletcher MJ; Daviglus ML; Carr JJ; Jacobs DR Jr

Prev Med. 2006 Mar;42(3):193-9. Epub 2006 Feb 15.

PubMed abstract

Does the association between serum endostatin, an endogenous anti-angiogenic protein, and acute myocardial infarction differ by race?

Authors: Iribarren C; Herrinton LJ; Darbinian JA; Tamarkin L; Malinowski D; Vogelman JH; Orentreich N; Baer D

Vasc Med. 2006 Feb;11(1):13-20.

PubMed abstract

Body mass index and risk for end-stage renal disease

Authors: Hsu CY; McCulloch CE; Iribarren C; Darbinian J; Go AS

Ann Intern Med. 2006 Jan 3;144(1):21-8.

PubMed abstract

History of depression, race, and cardiovascular risk in CARDIA

Authors: Knox S; Barnes A; Kiefe C; Lewis CE; Iribarren C; Matthews KA; Wong ND; Whooley M

Int J Behav Med. 2006;13(1):44-50.

PubMed abstract

Smoking status and common carotid artery intima-medial thickness among middle-aged men and women based on ultrasound measurement: a cohort study

Authors: Fan AZ; Paul-Labrador M; Merz CN; Iribarren C; Dwyer JH

BMC Cardiovasc Disord. 2006 Oct 26;6:42.

PubMed abstract

Lipoprotein-associated phospholipase A2 and cardiovascular risk: state of the evidence and future directions

Authors: Iribarren C

Arterioscler Thromb Vasc Biol. 2006 Jan;26(1):5-6.

PubMed abstract

The conundrum of increased burden of end-stage renal disease in Asians

Authors: Hall YN; Hsu CY; Iribarren C; Darbinian J; McCulloch CE; Go AS

Kidney Int. 2005 Nov;68(5):2310-6.

PubMed abstract

Sex and racial/ethnic disparities in outcomes after acute myocardial infarction: a cohort study among members of a large integrated health care delivery system in northern California

Authors: Iribarren C; Tolstykh I; Somkin CP; Ackerson LM; Brown TT; Scheffler R; Syme L; Kawachi I

Arch Intern Med. 2005 Oct 10;165(18):2105-13.

PubMed abstract

Directly measured second hand smoke exposure and asthma health outcomes

Authors: Eisner MD; Klein J; Hammond SK; Koren G; Lactao G; Iribarren C

Thorax. 2005 Oct;60(10):814-21.

PubMed abstract

The impact of allergy and pulmonary specialist care on emergency asthma utilization in a large managed care organization

Authors: Erickson S; Tolstykh I; Selby JV; Mendoza G; Iribarren C; Eisner MD

Health Serv Res. 2005 Oct;40(5 Pt 1):1443-65.

PubMed abstract

Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels

Authors: Carlson CS; Iribarren C; Reiner AP; et al.

Am J Hum Genet. 2005 Jul;77(1):64-77. Epub 2005 May 16.

PubMed abstract

Intensive care unit admission for asthma: a marker for severe disease

Authors: Eisner MD; Boland M; Tolstykh I; Mendoza G; Iribarren C

J Asthma. 2005 Jun;42(5):315-23.

PubMed abstract

Impact of depressive symptoms on adult asthma outcomes

Authors: Eisner MD; Katz PP; Lactao G; Iribarren C

Ann Allergy Asthma Immunol. 2005 May;94(5):566-74.

PubMed abstract

Elevated blood pressure and risk of end-stage renal disease in subjects without baseline kidney disease

Authors: Hsu CY; McCulloch CE; Darbinian J; Go AS; Iribarren C

Arch Intern Med. 2005 Apr 25;165(8):923-8.

PubMed abstract

Relation of echocardiographic left ventricular mass, geometry and wall stress, and left atrial dimension to coronary calcium in young adults (the CARDIA study)

Authors: Gardin JM; Iribarren C; Detrano RC; Liu K; Schreiner PJ; Loria CM; Wong ND

Am J Cardiol. 2005 Mar 1;95(5):626-9.

PubMed abstract

Causes and demographic, medical, lifestyle and psychosocial predictors of premature mortality: the CARDIA study

Authors: Iribarren C; Jacobs DR; Kiefe CI; Lewis CE; Matthews KA; Roseman JM; Hulley SB

Soc Sci Med. 2005 Feb;60(3):471-82.

PubMed abstract

Association of lipoprotein-associated phospholipase A2 mass and activity with calcified coronary plaque in young adults: the CARDIA study

Authors: Iribarren C; Gross MD; Darbinian JA; Jacobs DR Jr; Sidney S; Loria CM

Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):216-21. Epub 2004 Oct 21.

PubMed abstract

Analysis of late risk of systemic blood pressures <120/80 mm Hg

Authors: Ananthakrishnan S; Klatsky AL; Udaltsova N; Iribarren C; Guidry U

Am J Cardiol. 2004 Dec 15;94(12):1575-6.

PubMed abstract

Are patients with asthma at increased risk of coronary heart disease?

Authors: Iribarren C; Tolstykh IV; Eisner MD

Int J Epidemiol. 2004 Aug;33(4):743-8. Epub 2004 May 6.

PubMed abstract

Breast vascular calcification and risk of coronary heart disease, stroke, and heart failure

Authors: Iribarren C; Go AS; Tolstykh I; Sidney S; Johnston SC; Spring DB

J Womens Health (Larchmt). 2004 May;13(4):381-9; discussion 390-2.

PubMed abstract

Cohort study of exposure to environmental tobacco smoke and risk of first ischemic stroke and transient ischemic attack

Authors: Iribarren C; Darbinian J; Klatsky AL; Friedman GD

Neuroepidemiology. 2004 Jan-Apr;23(1-2):38-44.

PubMed abstract

Dietary intake of n-3, n-6 fatty acids and fish: relationship with hostility in young adults–the CARDIA study

Authors: Iribarren C; Markovitz JH; Jacobs DR Jr; Schreiner PJ; Daviglus M; Hibbeln JR

Eur J Clin Nutr. 2004 Jan;58(1):24-31.

PubMed abstract

Asthma is associated with weight gain in females but not males, independent of physical activity

Authors: Beckett WS; Jacobs DR Jr; Yu X; Iribarren C; Williams OD

Am J Respir Crit Care Med. 2001 Dec 1;164(11):2045-50.

PubMed abstract

Exposure to environmental tobacco smoke: association with personal characteristics and self reported health conditions

Authors: Iribarren C; Friedman GD; Klatsky AL; Eisner MD

J Epidemiol Community Health. 2001 Oct;55(10):721-8.

PubMed abstract

Cohort study of thyroid cancer in a San Francisco Bay area population

Authors: Iribarren C; Haselkorn T; Tekawa IS; Friedman GD

Int J Cancer. 2001 Sep 1;93(5):745-50.

PubMed abstract

Glycemic control and heart failure among adult patients with diabetes

Authors: Iribarren C; Karter AJ; Go AS; Ferrara A; Liu JY; Sidney S; Selby JV

Circulation. 2001 Jun 5;103(22):2668-73.

PubMed abstract

The association between asthma, asthma, therapeutic classes and hepatic enzyme elevation among adult HMO members

Authors: Iribarren C; Sidney S; Lydick E; Sorel ME; Eisner MD

Compr Ther. 2001 Summer;27(2):133-9.

PubMed abstract

Hospitalization for suicide attempt and completed suicide: epidemiological features in a managed care population

Authors: Iribarren C; Sidney S; Jacobs DR Jr; Weisner C

Soc Psychiatry Psychiatr Epidemiol. 2000 Jul;35(7):288-96.

PubMed abstract

Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease

Authors: Iribarren C; Sidney S; Sternfeld B; Browner WS

JAMA. 2000 Jun 7;283(21):2810-5.

PubMed abstract

Association of hostility with coronary artery calcification in young adults: the CARDIA study. Coronary Artery Risk Development in Young Adults

Authors: Iribarren C; Sidney S; Bild DE; Liu K; Markovitz JH; Roseman JM; Matthews K

JAMA. 2000 May 17;283(19):2546-51.

PubMed abstract

Invited commentary: low cholesterol and nonartherosclerotic disease risk: a persistently perplexing question

Authors: Jacobs DR Jr; Iribarren C

Am J Epidemiol. 2000 Apr 15;151(8):748-51.

PubMed abstract

Serum uric acid and risk of coronary heart disease: Atherosclerosis Risk in Communities (ARIC) Study

Authors: Moriarity JT; Folsom AR; Iribarren C; Nieto FJ; Rosamond WD

Ann Epidemiol. 2000 Apr;10(3):136-43.

PubMed abstract

Reexamining health effects of cigar smoking: fashionable, but may increase the risk of coronary heart disease

Authors: Iribarren C

Eur Heart J. 2000 Apr;21(7):505-6.

PubMed abstract

Cigarette smoking, alcohol consumption, and risk of ARDS: a 15-year cohort study in a managed care setting

Authors: Iribarren C; Jacobs DR Jr; Sidney S; Gross MD; Eisner MD

Chest. 2000 Jan;117(1):163-8.

PubMed abstract

Uric acid and serum antioxidant capacity: a reaction to atherosclerosis?

Authors: Nieto FJ; Iribarren C; Gross MD; Comstock GW; Cutler RG

Atherosclerosis. 2000 Jan;148(1):131-9.

PubMed abstract

Effect of cigar smoking on the risk of cardiovascular disease, chronic obstructive pulmonary disease, and cancer in men

Authors: Iribarren C; Tekawa IS; Sidney S; Friedman GD

N Engl J Med. 1999 Jun 10;340(23):1773-80.

PubMed abstract

Cohort study of serum total cholesterol and in-hospital incidence of infectious diseases

Authors: Iribarren C; Jacobs DR Jr; Sidney S; Claxton AJ; Feingold KR

Epidemiol Infect. 1998 Oct;121(2):335-47.

PubMed abstract

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