Jennifer O. Lam, PhD, MPH

People

Kaiser Permanente Division of Research
2000 Broadway
Oakland, CA 94612

(510) 891-3438 (phone)
jennifer.o.lam@kp.org

Jennifer Lam, PhD, MPH, is a Research Scientist at the Kaiser Permanente Northern California Division of Research. She received her bachelor's in English from the University of California, Berkeley, and both her master's in Public Health and doctorate in Epidemiology and International Health from Johns Hopkins University.

Dr. Lam has a background in the surveillance and epidemiology of infectious diseases, with expertise on HIV, HPV, and vaccine-preventable diseases. Her current research interests include cognitive impairment, frailty, substance use, and chronic disease prevention in people with HIV.

Current Position(s):

Research Scientist, Division of Research, Kaiser Permanente Northern California

Section Affiliations:

Primary Research Interests:

HIV and aging
Dementia and cognitive impairment
Geriatric syndromes and frailty
Infection-associated cancers
Infectious disease epidemiology

Studies

Electronic Health Record-Based Dementia Prediction for HIV Primary Care

The goal of this K01 Career Development Award is to receive mentored training on the development of risk prediction models for dementia in people with HIV using electronic health records data. The project will quantify the contribution of HIV- and non-HIV-related factors to risk of dementia; develop and validate a model to predict incident dementia in people with HIV; and investigate strategies to optimize translation and implementation of research findings into clinical care settings.
Investigator: Lam, Jennifer
Funder: National Institute of Allergy and Infectious Diseases

Neurocognitive Impairment and Dementia in People With and Without HIV

People with HIV infection are at increased risk for dementia, possibly due to the combined effects of HIV-associated inflammation and traditional dementia risk factors such as chronic drug use and cerebrovascular disease. With the widespread use of antiretroviral therapy for HIV treatment, severe forms of HIV-associated dementia are now uncommon, but milder forms of neurocognitive impairment affect up to 50% of people living with HIV. In preparation for future investigations on cognitive impairments in people aging with HIV, we are conducting a study to establish baseline knowledge on: 1) The prevalence of neurocognitive impairment and dementia, and 2) Risk factors for neurocognitive disorders among Kaiser Permanente Northern California patients with and without HIV infection.
Investigator: Lam, Jennifer
Funder: Northern California Community Benefit Programs

Highlighted Publications

Comparison of dementia incidence and prevalence between individuals with and without HIV infection in primary care from 2000 to 2016

Author(s): Lam JO; Lee C; Gilsanz P; Hou CE; Leyden WA; Satre DD; Flamm JA; Towner WJ; Horberg MA; Silverberg MJ

AIDS. 2021 Nov 24.

Current Position(s):

Section Affiliations:

Primary Research Interests:

Studies

Electronic Health Record-Based Dementia Prediction for HIV Primary Care

Neurocognitive Impairment and Dementia in People With and Without HIV

Highlighted Publications

Comparison of dementia incidence and prevalence between individuals with and without HIV infection in primary care from 2000 to 2016

Comparison of dementia risk after age 50 between individuals with and without HIV infection

Publications

Comparison of dementia incidence and prevalence between individuals with and without HIV infection in primary care from 2000 to 2016

Cancer in people with and without hepatitis C virus infection: comparison of risk before and after introduction of direct-acting antivirals

The relationship of smoking and unhealthy alcohol use to the HIV care continuum among people with HIV in an integrated health care system

Comparison of dementia risk after age 50 between individuals with and without HIV infection

Health System-Based Unhealthy Alcohol Use Screening and Treatment Comparing Demographically-Matched Participants With and Without HIV

Smoking and cessation treatment among persons with and without HIV in a U.S. integrated health system

Comparison of Overall and Comorbidity-Free Life Expectancy Between Insured Adults With and Without HIV Infection, 2000-2016

Effectiveness of 'catch-up' human papillomavirus vaccination to prevent cervical neoplasia in immunosuppressed and non-immunosuppressed women

Colorectal Cancer Screening in People With and Without HIV in an Integrated Health Care Setting

Interventions to Reduce Unhealthy Alcohol Use among Primary Care Patients with HIV: the Health and Motivation Randomized Clinical Trial

Hepatitis C treatment uptake and response among human immunodeficiency virus/hepatitis C virus-coinfected patients in a large integrated healthcare system.

Early outcomes of a high-resolution anoscopy-based anal cancer screening program among people with HIV enrolled in an integrated healthcare system

Effectiveness of catch-up human papillomavirus vaccination on incident cervical neoplasia in a US health-care setting: a population-based case-control study

Acceptability of high-resolution anoscopy for anal cancer screening in HIV-infected patients

Disparities in Initiation of Direct-Acting Antiviral Agents for Hepatitis C Virus Infection in an Insured Population.