skip to Main Content

Catherine Lee, PhD

Kaiser Permanente Researcher Profiles

Catherine  Lee, PhD

​Catherine Lee, PhD, is a biostatistician (research scientist) at the Kaiser Permanente Northern California Division of Research. Her methodological research focuses on the analysis of time-to-event outcomes. She has developed methods for relating sparsely collected time-varying biomarkers of Alzheimer’s disease to disease progression, and modeled transplant rejection among leukemia patients who have undergone stem cell transplantation. Dr. Lee’s current research includes the development of methods for joint risk prediction using semi-competing risks data. She received a PhD in mathematics from University of California, Los Angeles, and a PhD in biostatistics from Harvard University.

Current Positions

  • Research Scientist II

Section Affiliations

Primary Research Interests

  • Time-to-event outcomes
  • Risk prediction
  • Semi-competing risks


Association of primary lifetime occupational cognitive complexity and cognitive decline in a diverse cohort: Results from the KHANDLE study

Authors: Soh, Yenee;Eng, Chloe W;Mayeda, Elizabeth Rose;Whitmer, Rachel A;Lee, Catherine;Peterson, Rachel L;Mungas, Dan M;Glymour, M Maria;Gilsanz, Paola

Alzheimers Dement. 2023 Sep;19(9):3926-3935. Epub 2023-04-14.

PubMed abstract

Physician Assessment of Aortic Stenosis Severity, Quantitative Parameters, and Long-Term Outcomes: Results from the KP-VALVE Project

Authors: Solomon, Matthew D;Lange, David C;Ambrosy, Andrew P;Krishnaswami, Ashok;Nishimura, Rick;Go, Alan S;et al.

Am Heart J. 2023 Aug 06.

PubMed abstract

Body Composition, Relative Dose Intensity, and Adverse Events Among Patients with Colon Cancer

Authors: Cheng, En;Campbell, Kristin L;Schmitz, Kathryn H;Cespedes Feliciano, Elizabeth M;et al.

Cancer Epidemiol Biomarkers Prev. 2023 Jul 14.

PubMed abstract

Undiagnosed Cognitive Impairment and Impact on Instrumental Activities of Daily Living Among People With HIV Infection in Primary Care

Authors: Lam, Jennifer O;Hou, Craig E;Gilsanz, Paola;Lee, Catherine;Lea, Alexandra N;Satre, Derek D;Silverberg, Michael J

Open Forum Infect Dis. 2023 Jun;10(6):ofad284. Epub 2023-05-20.

PubMed abstract

Comparison of Mammography AI Algorithms with a Clinical Risk Model for 5-year Breast Cancer Risk Prediction: An Observational Study

Authors: Arasu, Vignesh A;Kornak, John;Lewis, Donald A;Yoon, Hyo-Chun;Lee, Catherine;et al.

Radiology. 2023 Jun;307(5):e222733.

PubMed abstract

Development and Validation of the Life Expectancy Estimator for Older Adults with Diabetes (LEAD): the Diabetes and Aging Study

Authors: Karter, Andrew J;Parker, Melissa M;Moffet, Howard H;Lipska, Kasia J;Laiteerapong, Neda;Grant, Richard W;Lee, Catherine;Huang, Elbert S

J Gen Intern Med. 2023 May 30.

PubMed abstract

Differences in proximal humerus and wrist fracture incidence among US Asian subgroups

Authors: Lo, Joan C;Lee, David R;Chandra, Malini;Zeltser, David W;Chu, Clarence E;Gordon, Nancy P;Darbinian, Jeanne A;Lee, Catherine

J Am Geriatr Soc. 2023 May 24.

PubMed abstract

Blood donor, component, and recipient-specific factors associated with venous thromboembolism in transfused hospitalized adult patients: Data from the recipient epidemiology and donor evaluation Study-III (REDS-III)

Authors: Goel, Ruchika; Plimier, Colleen; Lee, Catherine; Tobian, Aaron A R; Josephson, Cassandra D; Hod, Eldad A; Roubinian, Nareg H

Transfusion. 2023 May;63(5):925-932. Epub 2023-02-25.

PubMed abstract

Perinatal Outcomes After Bariatric Surgery Compared With a Matched Control Group

Authors: Boller, Marie J; Xu, Fei; Lee, Catherine; Sridhar, Sneha; Greenberg, Mara B; Hedderson, Monique M

Obstet Gynecol. 2023 Mar 01;141(3):583-591. Epub 2023-02-02.

PubMed abstract

Sex- and ethnic-specific patterns in the incidence of hip fracture among older US Asian and non-Hispanic White adults

Authors: Lo, Joan C; Chandra, Malini; Lee, David R; Darbinian, Jeanne A; Gordon, Nancy P; Zeltser, David W; Grimsrud, Christopher D; Lee, Catherine

J Am Geriatr Soc. 2023 Feb 15.

PubMed abstract

Risk of venous thromboembolism in non-respiratory and respiratory presentations of COVID-19 in critically ill patients

Authors: Roubinian, Nareg H; Vinson, David R; Pai, Ashok P; Myers, Laura C; Skarbinski, Jacek; Lee, Catherine; Mark, Dustin G; Liu, Vincent X

Chest. 2023 Feb 12.

PubMed abstract

Risk of posthospital venous thromboembolism in patients with COVID-19 varies by SARS-CoV-2 period and vaccination status

Authors: Roubinian, Nareg H; Vinson, David R; Knudson-Fitzpatrick, Tess Wheeler; Mark, Dustin G; Skarbinski, Jacek; Lee, Catherine; Liu, Vincent X; Pai, Ashok P

Blood Adv. 2023 Jan 10;7(1):141-144.

PubMed abstract

Pregnancy post-bariatric surgery: Improved outcomes with telephonic nutritional management program

Authors: Hedderson, Monique M; Boller, Marie; Xu, Fei; Lee, Catherine; Sridhar, Sneha; Greenberg, Mara

Obes Res Clin Pract. 2023 Mar-Apr;17(2):144-150. Epub 2023-03-10.

PubMed abstract

Association between anaemia and hospital readmissions in patients undergoing major surgery requiring postoperative intensive care

Authors: Warner, M A; Hanson, A C; Plimier, C; Lee, C; Liu, V X; Richards, T; Kor, D J; Roubinian, N H

Anaesthesia. 2023 Jan;78(1):45-54. Epub 2022-09-08.

PubMed abstract

Predicting Post-Sepsis Cardiovascular Events with Death as a Competing Risk

Authors: Myers, Laura C; Lee, Catherine; Go, Alan S; Liu, Vincent X; Walkey, Allan J; et al.

Ann Am Thorac Soc. 2023 Jan;20(1):145-148.

PubMed abstract

High-sensitivity troponin I is associated with cardiovascular outcomes but not with breast arterial calcification among postmenopausal women

Authors: Iribarren, Carlos; Chandra, Malini; Lee, Catherine; Sanchez, Gabriela; Sam, Danny L; Azamian, Farima Faith; Cho, Hyo-Min; Ding, Huanjun; Wong, Nathan D; Molloi, Sabee

Int J Cardiol Cardiovasc Risk Prev. 2022 Dec;15:200157. Epub 2022-11-01.

PubMed abstract

A large genome-wide association study of QT interval length utilizing electronic health records

Authors: Hoffmann, Thomas J; Lu, Meng; Oni-Orisan, Akinyemi; Lee, Catherine; Risch, Neil; Iribarren, Carlos

Genetics. 2022 Nov 30;222(4).

PubMed abstract

Association of Thoracic Aortic Aneurysm Size With Long-term Patient Outcomes: The KP-TAA Study

Authors: Solomon, Matthew D; Lee, Catherine; Chang, Robert; Go, Alan S; Kaiser Permanente Northern California Center for Thoracic Aortic Disease ,; et al.

JAMA Cardiol. 2022 Nov 01;7(11):1160-1169.

PubMed abstract

Risk of severe COVID-19 infection among adults with prior exposure to children

Authors: Solomon, Matthew D; Escobar, Gabriel J; Lu, Yun; Schlessinger, David; Steinman, Jonathan B; Steinman, Lawrence; Lee, Catherine; Liu, Vincent X

Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2204141119. Epub 2022-07-27.

PubMed abstract

Predicting obstructive sleep apnea severity in children referred for polysomnography: use of the Pediatric Sleep Questionnaire and Subscales

Authors: Bseikri, Mustafa; Zhang, Jie; Kirley, Jocelyn; Lee, Catherine; Castillo, Adrienne; Feliciano, Elizabeth M Cespedes

Sleep Breath. 2022 May 28.

PubMed abstract

Exploratory analysis of novel electronic health record variables for quantification of healthcare delivery strain, prediction of mortality, and prediction of imminent discharge

Authors: Lee, Catherine; Lawson, Brian L; Mann, Ariana J; Liu, Vincent X; Myers, Laura C; Schuler, Alejandro; Escobar, Gabriel J

J Am Med Inform Assoc. 2022 05 11;29(6):1078-1090.

PubMed abstract

Effect of Lifestyle Coaching or Enhanced Pharmacotherapy on Blood Pressure Control Among Black Adults With Persistent Uncontrolled Hypertension: A Cluster Randomized Clinical Trial

Authors: Nguyen-Huynh, Mai N; Young, Joseph D; Ovbiagele, Bruce; Alexander, Janet G; Alexeeff, Stacey; Lee, Catherine; Blick, Noelle; Caan, Bette J; Go, Alan S; Sidney, Stephen

JAMA Netw Open. 2022 May 02;5(5):e2212397. Epub 2022-05-02.

PubMed abstract

Contribution of Maternal Cardiometabolic Risk Factors to Racial-Ethnicity Disparities in Preterm Birth Subtypes

Authors: Hedderson, Monique M; Xu, Fei; Dayo, Olumayowa M; Liu, Emily; Sridhar, Sneha; Lee, Catherine; Greenberg, Mara

Am J Obstet Gynecol MFM. 2022 05;4(3):100608. Epub 2022-03-04.

PubMed abstract

Primary care telemedicine during the COVID-19 pandemic: patient’s choice of video versus telephone visit

Authors: Huang, Jie; Graetz, Ilana; Millman, Andrea; Gopalan, Anjali; Lee, Catherine; Muelly, Emilie; Reed, Mary E

JAMIA Open. 2022 Apr;5(1):ooac002. Epub 2022-01-19.

PubMed abstract

Breast Arterial Calcification: a Novel Cardiovascular Risk Enhancer Among Postmenopausal Women

Authors: Iribarren, Carlos; Chandra, Malini; Lee, Catherine; Sanchez, Gabriela; Sam, Danny L; Azamian, Farima Faith; Cho, Hyo-Min; Ding, Huanjun; Wong, Nathan D; Molloi, Sabee

Circ Cardiovasc Imaging. 2022 03;15(3):e013526. Epub 2022-03-15.

PubMed abstract

Comparison of dementia incidence and prevalence between individuals with and without HIV infection in primary care from 2000 to 2016

Authors: Lam, Jennifer O; Lee, Catherine; Gilsanz, Paola; Hou, Craig E; Leyden, Wendy A; Satre, Derek D; Flamm, Jason A; Towner, William J; Horberg, Michael A; Silverberg, Michael J

AIDS. 2022 03 01;36(3):437-445.

PubMed abstract

Age-Adjusted Mortality Rates and Age and Risk-Associated Contributions to Change in Heart Disease and Stroke Mortality, 2011-2019 and 2019-2020

Authors: Sidney, Stephen; Lee, Catherine; Liu, Jennifer; Khan, Sadiya S; Lloyd-Jones, Donald M; Rana, Jamal S

JAMA Netw Open. 2022 03 01;5(3):e223872. Epub 2022-03-01.

PubMed abstract

Impact of the Affordable Care Act on Colorectal Cancer Incidence and Mortality

Authors: Lee, Catherine; Kushi, Lawrence H; Reed, Mary E; Eldridge, Elizabeth H; Lee, Jeffrey K; Zhang, Jie; Spiegelman, Donna

Am J Prev Med. 2022 03;62(3):387-394. Epub 2021-11-08.

PubMed abstract

Torsade de pointes: A nested case-control study in an integrated healthcare delivery system

Authors: Mantri, Neha; Lu, Meng; Zaroff, Jonathan G; Risch, Neil; Hoffmann, Thomas; Oni-Orisan, Akinyemi; Lee, Catherine; Iribarren, Carlos

Ann Noninvasive Electrocardiol. 2022 01;27(1):e12888. Epub 2021-09-21.

PubMed abstract

Treatment and Follow-up Care Associated With Patient-Scheduled Primary Care Telemedicine and In-Person Visits in a Large Integrated Health System

Authors: Reed, Mary; Huang, Jie; Graetz, Ilana; Muelly, Emilie; Millman, Andrea; Lee, Catherine

JAMA Netw Open. 2021 11 01;4(11):e2132793. Epub 2021-11-01.

PubMed abstract

QT Interval Dynamics and Cardiovascular Outcomes: A Cohort Study in an Integrated Health Care Delivery System

Authors: Mantri, Neha; Lu, Meng; Zaroff, Jonathan G; Risch, Neil; Hoffmann, Thomas; Oni-Orisan, Akinyemi; Lee, Catherine; Jorgenson, Eric; Iribarren, Carlos

J Am Heart Assoc. 2021 10 05;10(19):e018513. Epub 2021-09-28.

PubMed abstract


Authors: Escobar, Gabriel J; Schuler, Alejandro; Lee, Catherine

Am J Obstet Gynecol. 2021 08;225(2):208. Epub 2021-04-23.

PubMed abstract

Racial Disparities in COVID-19 Testing and Outcomes : Retrospective Cohort Study in an Integrated Health System

Authors: Escobar, Gabriel J; Adams, Alyce S; Liu, Vincent X; Soltesz, Lauren; Chen, Yi-Fen Irene; Parodi, Stephen M; Ray, G Thomas; Myers, Laura C; Ramaprasad, Charulata M; Dlott, Richard; Lee, Catherine

Ann Intern Med. 2021 06;174(6):786-793. Epub 2021-02-09.

PubMed abstract

Comparison of dementia risk after age 50 between individuals with and without HIV infection

Authors: Lam, Jennifer O; Hou, Craig E; Hojilla, J Carlo; Anderson, Alexandra N; Gilsanz, Paola; Alexeeff, Stacey E; Levine-Hall, Tory; Hood, Nicole; Lee, Catherine; Satre, Derek D; Silverberg, Michael J

AIDS. 2021 04 01;35(5):821-828.

PubMed abstract

Dual trajectories of physical activity and blood lipids in midlife women: The Study of Women’s Health Across the Nation

Authors: Badon, Sylvia E; Gabriel, Kelley Pettee; Karvonen-Gutierrez, Carrie; Sternfeld, Barbara; Gold, Ellen B; Waetjen, L Elaine; Lee, Catherine; Avalos, Lyndsay A; El Khoudary, Samar R; Hedderson, Monique M

Maturitas. 2021 Apr;146:49-56. Epub 2021-02-06.

PubMed abstract

Recruitment strategies and design considerations in a trial of resistance training to prevent dose-limiting toxicities in colon cancer patients undergoing chemotherapy

Authors: Caan, Bette J; Meyerhardt, Jeffrey A; Brown, Justin C; Campbell, Kristin L; Cespedes Feliciano, Elizabeth M; Lee, Catherine; Ross, Michelle C; Quinney, Sara; Quesenberry, Charles; Sternfeld, Barbara; Schmitz, Kathryn H

Contemp Clin Trials. 2021 02;101:106242. Epub 2020-12-07.

PubMed abstract


Authors: Escobar, Gabriel J; Soltesz, Lauren; Schuler, Alejandro; Niki, Hamid; Malenica, Ivana; Lee, Catherine

Am J Obstet Gynecol. 2021 02;224(2):137-147.e7. Epub 2020-10-22.

PubMed abstract

Fitting a shared frailty illness-death model to left-truncated semi-competing risks data to examine the impact of education level on incident dementia

Authors: Lee, Catherine; Gilsanz, Paola; Haneuse, Sebastien

BMC Med Res Methodol. 2021 01 11;21(1):18. Epub 2021-01-11.

PubMed abstract

Bone Mineral Density in Older U.S. Filipino, Chinese, Japanese, and White Women

Authors: Lo, Joan C; Chandra, Malini; Lee, Catherine; Darbinian, Jeanne A; Ramaswamy, Mohan; Ettinger, Bruce

J Am Geriatr Soc. 2020 11;68(11):2656-2661. Epub 2020-10-12.

PubMed abstract

The Covid-19 Pandemic and the Incidence of Acute Myocardial Infarction

Authors: Solomon MD; McNulty EJ; Rana JS; Leong TK; Lee C; Sung SH; Ambrosy AP; Sidney S; Go AS

N Engl J Med. 2020 08 13;383(7):691-693. Epub 2020-05-19.

PubMed abstract

Time-to-event analysis when the event is defined on a finite time interval

Authors: Lee C; Lee SJ; Haneuse S

Stat Methods Med Res. 2020 06;29(6):1573-1591. Epub 2019-08-22.

PubMed abstract

Patient Characteristics Associated With Choosing a Telemedicine Visit vs Office Visit With the Same Primary Care Clinicians

Authors: Reed ME; Huang J; Graetz I; Lee C; Muelly E; Kennedy C; Kim E

JAMA Netw Open. 2020 06 01;3(6):e205873. Epub 2020-06-01.

PubMed abstract

Additive effects of blood donor smoking and gamma irradiation on outcome measures of red blood cell transfusion

Authors: DeSimone RA; Plimier C; Lee C; Kanias T; Cushing MM; Sachais BS; Kleinman S; Busch MP; Roubinian NH

Transfusion. 2020 May 01.

PubMed abstract

Prediction of Occult Uterine Sarcoma prior to Hysterectomy for Women with Leiomyoma or Abnormal Bleeding

Authors: Lentz SE; Zaritsky E; Tucker LY; Lee C; Lazo IM; Niihara A; Yamamoto M; Raine-Bennett T

J Minim Invasive Gynecol. 2020 May - Jun;27(4):930-937.e1. Epub 2019-07-25.

PubMed abstract

Cumulative Adherence to Secondary Prevention Guidelines and Mortality After Acute Myocardial Infarction

Authors: Solomon MD; Leong TK; Levin E; Rana JS; Jaffe MG; Sidney S; Sung SH; Lee C; DeMaria A; Go AS

J Am Heart Assoc. 2020 03 17;9(6):e014415. Epub 2020-03-05.

PubMed abstract

Adjuvant endocrine therapy for breast cancer patients: impact of a health system outreach program to improve adherence

Authors: Lee C; Check DK; Manace Brenman L; Kushi LH; Epstein MM; Neslund-Dudas C; Pawloski PA; Achacoso N; Laurent C; Fehrenbacher L; Habel LA

Breast Cancer Res Treat. 2020 Feb;180(1):219-226. Epub 2020-01-23.

PubMed abstract

Association of donor age, body mass index, hemoglobin, and smoking status with in-hospital mortality and length of stay among red blood cell-transfused recipients

Authors: Roubinian NH; Lee C; NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III); et al.

Transfusion. 2019 11;59(11):3362-3370. Epub 2019-10-11.

PubMed abstract

Effect of donor, component and recipient characteristics on hemoglobin increments following red blood cell transfusion

Authors: Roubinian NH; Plimier C; Woo JP; Lee C; Bruhn R; Liu VX; Escobar GJ; Kleinman SH; Triulzi DJ; Murphy EL; Busch MP

Blood. 2019 09 26;134(13):1003-1013. Epub 2019-07-26.

PubMed abstract

Association of Blood Donor Sex and Prior Pregnancy With Mortality Among Red Blood Cell Transfusion Recipients

Authors: Edgren G; Lee C; Roubinian NH; NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) Group; et al.

JAMA. 2019 06 11;321(22):2183-2192.

PubMed abstract

SemiCompRisks: An R Package for the Analysis of Independent and Cluster-correlated Semi-competing Risks Data

Authors: Alvares, Danilo; Haneuse, Sebastien; Lee, Catherine; Lee, Kyu Ha

R J. 2019 Jun;11(1):376-400. Epub 2019-08-20.

PubMed abstract

Reproductive period and risk of dementia in a diverse cohort of health care members

Authors: Gilsanz P; Lee C; Corrada MM; Kawas CH; Quesenberry CP; Whitmer RA

Neurology. 2019 04 23;92(17):e2005-e2014. Epub 2019-03-28.

PubMed abstract

Incidence of dementia after age 90 in a multiracial cohort

Authors: Gilsanz P; Corrada MM; Kawas CH; Mayeda ER; Glymour MM; Quesenberry CP; Lee C; Whitmer RA

Alzheimers Dement. 2019 04;15(4):497-505. Epub 2019-02-20.

PubMed abstract

Long-Term Outcomes Among Patients Discharged From the Hospital With Moderate Anemia: A Retrospective Cohort Study

Authors: Roubinian NH; Murphy EL; Mark DG; Triulzi DJ; Carson JL; Lee C; Kipnis P; Kleinman S; Liu VX; Escobar GJ

Ann Intern Med. 2019 01 01;170(1):80.

PubMed abstract

Kidney function, proteinuria and breast arterial calcification in women without clinical cardiovascular disease: The MINERVA study

Authors: Parikh RV; Iribarren C; Lee C; Levine-Hall T; Tan TC; Sanchez G; Ding H; Bidgoli FA; Molloi S; Go AS

PLoS ONE. 2019;14(1):e0210973. Epub 2019-01-17.

PubMed abstract

A Pre-Pregnancy Biomarker Risk Score Improves Prediction of Future Gestational Diabetes

Authors: Badon SE; Zhu Y; Sridhar SB; Xu F; Lee C; Ehrlich SF; Quesenberry CP; Hedderson MM

J Endocr Soc. 2018 Oct 01;2(10):1158-1169. Epub 2018-09-13.

PubMed abstract

​Intensive residential treatment for severe obsessive-compulsive disorder: characterizing treatment course and predictors of response.

Authors: Brennan BP; Lee C; Elias JA; Crosby JM; Mathes BM; Andre MC; Gironda CM; Pope HG Jr; Jenike MA; Fitzmaurice GM; Hudson JI;

​J Psychiatr Res. 2014 Sep;56:98-105. doi: 10.1016/j.jpsychires.2014.05.008. Epub 2014 May 23.

PubMed abstract

​Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype.

Authors: Ringman JM; Elashoff D; Geschwind DH; Welsh BT; Gylys KH; Lee C; Cummings JL; Cole GM

​Arch Neurol. 2012 Jun;69(6):757-64. doi: 10.1001/archneurol.2012.277.

PubMed abstract

​Estimating sample sizes for predementia Alzheimer’s trials based on the Alzheimer’s Disease Neuroimaging Initiative

Authors: Grill JD; Di L; Lu PH; Lee C; Ringman J; Apostolova LG; Chow N; Kohannim O; Cummings JL; Thompson PM; Elashoff D; Alzheimer's Disease Neuroimaging Initiative

​Neurobiol Aging. 2013 Jan;34(1):62-72. doi: 10.1016/j.neurobiolaging.2012.03.006. Epub 2012 Apr 13.

PubMed abstract

​Single-institution, multidisciplinary experience with surgical resection of primary chest wall sarcomas.

Authors: Kachroo P; Pak PS; Sandha HS; Lee C; Elashoff D; Nelson SD; Chmielowski B; Selch MT; Cameron RB; Holmes EC; Eilber FC; Lee JM

​J Thorac Oncol. 2012 Mar;7(3):552-8. doi: 10.1097/JTO.0b013e31824176df.

PubMed abstract

​Dermatologic care in the homeless and underserved populations: observations from the Venice Family Clinic

Authors: Grossberg AL; Carranza D, Lamp; K, Chiu MW; Lee C; Craft N

​Cutis. 2012 Jan;89(1):25-32.

PubMed abstract

​The MCCB impairment profile for schizophrenia outpatients: results from the MATRICS psychometric and standardization study

Authors: Kern RS; Gold JM; Dickinson D; Green MF; Nuechterlein KH; Baade LE; Keefe RS; Mesholam-Gately RI; Seidman LJ; Lee C; Sugar CA; Marder SR

​Schizophr Res. 2011 Mar;126(1-3):124-31. doi: 10.1016/j.schres.2010.11.008. Epub 2010 Dec 14.

PubMed abstract

Back To Top