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Jeffrey K. Lee, MD, MPH

jeffrey.k.lee@kp.org

Kaiser Permanente Researcher Profiles

Jeffrey  Lee, MD, MPH

Jeffrey K. Lee, MD, MPH, is a Research Scientist I at the Kaiser Permanente Northern California Division of Research and an attending gastroenterologist at Kaiser Permanente San Francisco Medical Center. His clinical focus is in general gastroenterology, colorectal cancer prevention, and hereditary gastrointestinal cancer syndromes. His research interests include: colorectal cancer prevention, gastrointenstinal cancer prevention, pharmacoepidemiology, diagnostic testing for gastrointestinal cancers, and improving the quality and safety of endoscopy and colonoscopy.

Dr. Lee holds a Bachelor of Arts from the University of California, Berkeley, a Masters in Clinical Research from the University of California, San Diego, and a Doctorate in Medicine, also from UCSD. After medical school, he completed an internal medicine residency at UCSD; and a gastroenterology fellowship at the University of California, San Francisco. Prior to joining Kaiser Permanente, he practiced gastroenterology at UCSF Medical Center for several years.

Current Positions

  • Research Scientist I, Division of Research, Kaiser Permanente Northern California
  • Attending Gastroenterologist, Kaiser Permanente, San Francisco Medical Center
  • Assistant Clinical Professor of Medicine, University of California, San Francisco

Section Affiliations

Studies

Predictive Power of Quantitative FIT for Colorectal Cancer Screening: QUANTI-FI Study

This study will evaluate the performance characteristics of FIT for screening colorectal cancer and advanced adenomas at varying fecal hemoglobin concentration levels in an asymptomatic, average-risk population. It also will evaluate the predictive role of fecal hemoglobin concentration among subjects with two negative FITs for the subsequent risk of CRC and advanced neoplasia.

Investigator: Lee, Jeffrey

Funder: Polymedco, LLC.

Personalizing Post-Polypectomy Surveillance for Colorectal Cancer Prevention

Despite strong guidance supporting colorectal cancer screening initiation at age 45-50, relatively little is known about what to do for the subsequent 30+ years after screening. The goals of this proposal are to develop and internally validate a clinical (e.g., age, sex, body mass index, family history of colorectal cancer) and endoscopic (e.g., polyp findings) risk score to predict advanced neoplasia after screening; and determine the added value of incorporating a polygenic risk score to this model; validate the performance of the comprehensive risk model using an independent dataset with complete genetic data, and prior screening and clinicopathologic data; identify the optimal strategy for surveillance using information from Aims 1-2 by modeling within the established microsimulation model; and engage key stakeholders (i.e., patients, providers, and healthcare administrators) of the model and elicit their willingness on implementing this tool in clinical practice.

Investigator: Lee, Jeffrey

Funder: National Cancer Institute

Comparison of Survival Rates Across Racial/Ethnic Groups Among Young Adults Diagnosed with Early-Onset Colorectal Cancer in a Large, Community-Based Population.

This study will examine racial differences in overall survival among young adults 50 years of age diagnosed with early-onset colorectal cancer in a large, community- based, fully insured population with access to complete primary and specialty care to identify differences in risk factors, access to care, and treatment effectiveness and adherence.

Investigator: Lee, Jeffrey

Funder: Genentech, Inc.

COmprehensive risk Model for Predicting Advanced neoplasia on Surveillance Study (COMPASS)

The goals of this project are to develop and validate a colorectal neoplasia risk prediction model among average-risk patients who underwent a baseline colonoscopy; estimate the risk of advanced neoplasia among patients with newly diagnosed Lynch Syndrome; and develop and validate a colorectal neoplasia risk prediction model among patients with newly diagnosed Lynch Syndrome.

Investigator: Lee, Jeffrey

Funder: Janssen Pharmaceuticals, Inc.

Rates and Risk Factors of Post-Colonoscopy Colorectal Cancer in a Large, United States Population-based Cohort Study

Colorectal cancer (CRC) is the third leading cause of cancer death in the United States. Colonoscopy can reduce CRC incidence and deaths through removal of precancerous adenomatous polyps (adenomas) and detection of cancer at an earlier, more treatable stage. However, some patients develop CRC after a colonoscopy in which no cancer is diagnosed. The World Endoscopy Organization (WEO) defines post-colonoscopy colorectal cancers (PCCRCs) as CRC diagnosed 6 months after a colonoscopy that did not detect cancer. PCCRC is poorly understood as there is uncertainty about how often these cancers occur, their likely etiologies, the risk factors for these cancers, and whether they are more lethal than detected CRCs. To address these uncertainties, the WEO published a consensus statement to provide comprehensive guidance for the investigation of PCCRC cases. Their recommendations include a standardized definition for PCCRC, a defined method for calculating PCCRC rates, and standardized methods for performing qualitative reviews of cases to determine their likely etiology. The primary goal of the proposed study is to use recently published WEO methods to determine PCCRC rates, the likely etiologies for these cancers, their risk factors, and prognoses for PCCRC in the large integrated healthcare setting of Kaiser Permanente Northern California (KPNC).

Investigator: Lee, Jeffrey

Funder: Northern California Community Benefit Programs

De-Implementation of Outdated Colonoscopy Surveillance Interval Recommendations among Patients with Low-Risk Adenomas (DESIRE)

Recent guidelines have extended surveillance intervals for patients with low-risk adenomas from 5 years to 10. However, it remains unclear how to implement this change. In a pragmatic randomized 2-arm study of 1,000 patients with a history of low-risk adenomas and a standing 5-year surveillance recommendation, we will compare the effectiveness of secure messaging versus mailed outreach for adopting the new 10-year surveillance interval recommendation, continuing with the standing 5-year recommendation, or requesting a provider encounter (e.g., clinic or virtual visit) for shared decision making.

Investigator: Lee, Jeffrey

Funder: TPMG Delivery Science Projects Program

Optimizing Long-Term Post-Polypectomy Surveillance for Colorectal Cancer Prevention Using a Prediction Rule Developed from a Large, Community-Based Cohort

​Screening has been shown to reduce colorectal cancer incidence and mortality. However, screening has resulted in a growing cohort of patients with adenomatous polyps (adenomas), and little is known about effectively managing their post-polypectomy surveillance. With limited data available in the literature to determine the appropriate timing and frequency of follow-up colonoscopy for patients after adenoma removal, recommendations for post-polypectomy surveillance from our national guidelines have been imprecise at best. To fill this knowledge gap, this project aims to: 1) determine the long- term colorectal cancer risk in patients after colonoscopic polypectomy in a very large “real world” community-based population; 2) identify patient-, polyp-, and exam-related risk factors associated with incident colorectal cancer in these patients; and 3) develop a risk prediction model that will identify post- polypectomy patients at high and low risk for developing subsequent colorectal cancer.

Investigator: Lee, Jeffrey

Funder: National Cancer Institute

Publications

Impact of a scalable training program on the quality of colonoscopy performance and risk of post-colonoscopy colorectal cancer

Authors: Corley, Douglas A;Jensen, Christopher D;Lee, Jeffrey K;Contreras, Richard;Fireman, Bruce H;Quesenberry, Charles P;et al.

Gastrointest Endosc. 2023 Oct;98(4):609-617. Epub 2023-04-23.

PubMed abstract

Brief Communication: The Contemporary Probability of Occult Colorectal Cancer in Patients with Colitis-Related Dysplasia undergoing Colectomy

Authors: Boparai, Eshandeep S;Lee, Jeffrey K;Zhu, Shiyun;Shirazi, Aida;Velayos, Fernando S

Am J Gastroenterol. 2023 Aug 01;118(8):1453-1456. Epub 2023-04-11.

PubMed abstract

Declines in colorectal cancer incidence and mortality rates slow among older adults

Authors: Murphy, Caitlin C;Lee, Jeffrey K;Liang, Peter S;May, Folasade P;Zaki, Timothy A

Clin Gastroenterol Hepatol. 2023 Jun 10.

PubMed abstract

ASGE Guideline on the role of endoscopy in the diagnosis of malignancy in biliary strictures of undetermined etiology: Summary and Recommendations

Authors: Fujii-Lau, Larissa L;Law, Joanna K;ASGE Standards of Practice Committee Chair (2020-2023),;et al.

Gastrointest Endosc. 2023 Jun 10.

PubMed abstract

ASGE Guideline on role of endoscopy in the diagnosis of malignancy in biliary strictures of undetermined etiology: Methodology and Review of Evidence

Authors: Fujii-Lau, Larissa L;Law, Joanna K;ASGE Standards of Practice Committee Chair (2020-2023),;et al.

Gastrointest Endosc. 2023 Jun 10.

PubMed abstract

Epidemiologic Burden and Projections for Eosinophilic Esophagitis-Associated Emergency Department Visits in the United States (2009-2030)

Authors: Lam, Angela Y;Ma, Christopher;et al.

Clin Gastroenterol Hepatol. 2023 May 08.

PubMed abstract

Overall and Annual Post-Colonoscopy Colorectal Cancer Rates in a Large Integrated Healthcare Setting: A Cross-sectional Study

Authors: Lee, Jeffrey K; H-E Kang, James; Merchant, Sophie A; Jensen, Christopher D; Burr, Nicholas E; Corley, Douglas A

Clin Gastroenterol Hepatol. 2023 Mar 23.

PubMed abstract

Risk-stratified screening for colorectal cancer using genetic and environmental risk factors: A cost-effectiveness analysis based on real-world data

Authors: van den Puttelaar, Rosita; Lee, Jeffrey K; Sakoda, Lori C; Corley, Douglas A; Lansdorp-Vogelaar, Iris; et al.

Clin Gastroenterol Hepatol. 2023 Mar 09.

PubMed abstract

Increased Risk of Hospitalization, Surgery and Venous Thromboembolism Among Patients with Inflammatory Bowel Disease and Malnutrition in a Large, Community-Based Healthcare System

Authors: Fine, Liat S; Zhu, Shiyun; Shirazi, Aida; Lee, Jeffrey K; Velayos, Fernando S

Am J Gastroenterol. 2023 Mar 09.

PubMed abstract

Validation of a genetic-enhanced risk prediction model for colorectal cancer in a large community-based cohort

Authors: Su, Yu-Ru; Sakoda, Lori C; Lee, Jeffrey K; Corley, Douglas A; Hsu, Li; et al.

Cancer Epidemiol Biomarkers Prev. 2023 Mar 06;32(3):353-362.

PubMed abstract

Dietary inflammatory and insulinemic potential, risk of hepatocellular carcinoma and chronic liver disease mortality

Authors: Long, Lu; Lee, Jeffrey K; Zhang, Xuehong; et al.

JNCI Cancer Spectr. 2023 Mar 01;7(2).

PubMed abstract

Post-Colonoscopy Colorectal Cancer Etiologies in a Large Integrated US Health Care Setting

Authors: Leung, Lawrence Jun; Lee, Jeffrey K; Merchant, Sophie A; Jensen, Christopher D; Alam, Asim; Corley, Douglas A

Gastroenterology. 2023 Mar;164(3):470-472.e3. Epub 2022-12-01.

PubMed abstract

Successful Design and Implementation of a POEM Program for Achalasia in an Integrated Healthcare System

Authors: Leung, Lawrence Jun; Ma, Gene K; Lee, Jeffrey K; Fukami, Norio; Chang, Howard; Svahn, Jonathan; Xu, Ming-Ming; Lam, Steven; Risbud, Amita; Jue, Terry L

Dig Dis Sci. 2023 Feb 01:1-9.

PubMed abstract

Biopsy of Non-tumor Sites After Biopsy of a Colorectal Cancer is not Associated With Metachronous Cancers: A Case-control Study

Authors: Lam, Angela Y; Lee, Jeffrey K; Merchant, Sophie; Jensen, Christopher D; Sedki, Mai; Corley, Douglas A

Clin Gastroenterol Hepatol. 2023 Feb;21(2):487-496.e3. Epub 2022-05-26.

PubMed abstract

Combining Asian-European Genome-Wide Association Studies of Colorectal Cancer Improves Risk Prediction Across Race and Ethnicity

Authors: Thomas, Minta; Sakoda, Lori C; Lee, Jeffrey K; Corley, Douglas A; Hsu, Li; et al.

medRxiv. 2023 Jan 19.

PubMed abstract

The New Kids on the Block: Emerging Complementary Colonoscopy Quality Metrics

Authors: Lam, Angela Y; Lee, Jeffrey K

Clin Gastroenterol Hepatol. 2023 Jan;21(1):26-28. Epub 2022-05-10.

PubMed abstract

Risk of nonalcoholic fatty liver disease and associations with gastrointestinal cancers

Authors: McHenry, Scott; Zong, Xiaoyu; Shi, Mengyao; Fritz, Cassandra D L; Pedersen, Katrina S; Peterson, Linda R; Lee, Jeffrey K; Fields, Ryan C; Davidson, Nicholas O; Cao, Yin

Hepatol Commun. 2022 Dec;6(12):3299-3310. Epub 2022-10-11.

PubMed abstract

GA White Paper: Challenges and Gaps in Innovation for the Performance of Colonoscopy for Screening and Surveillance of Colorectal Cancer

Authors: Komanduri, Srinadh; Lieberman, David; Muthusamy, V Raman; et al.

Clin Gastroenterol Hepatol. 2022 Oct;20(10):2198-2209.e3. Epub 2022-06-07.

PubMed abstract

Novel, Emerging Risk Factors for Colorectal Cancer Remain Understudied

Authors: Burnett-Hartman, Andrea N; Murphy, Caitlin C; Lee, Jeffrey K

Gastroenterology. 2022 09;163(3):574-576. Epub 2022-07-07.

PubMed abstract

CMV Colitis Masquerading as MALT Lymphoma in an Immunocompetent Patient

Authors: Lam, Angela Y; Lee, Jeffrey K

ACG Case Rep J. 2022 Sep;9(9):e00851. Epub 2022-09-01.

PubMed abstract

Impact of the COVID-19 pandemic on fecal immunochemical testing, colonoscopy services, and colorectal neoplasia detection in a large United States community-based population

Authors: Lee, Jeffrey K; Li, Dan; Corley, Douglas A; Levin, Theodore R; et al.

Gastroenterology. 2022 09;163(3):723-731.e6. Epub 2022-05-14.

PubMed abstract

Association of Physician Adenoma Detection Rates With Postcolonoscopy Colorectal Cancer

Authors: Schottinger, Joanne E; Lee, Jeffrey K; Fireman, Bruce H; Quesenberry, Charles P; Corley, Douglas A; et al.

JAMA. 2022 06 07;327(21):2114-2122.

PubMed abstract

Reduced Implementation and Completion of Average-Risk Annual Fecal Immunochemical Test Colorectal Cancer Screening in Black Patients Aged 45-49 Years

Authors: Coronado, Gloria D; Dickerson, John F; Burnett-Hartman, Andrea N; Carethers, John M; Lee, Jeff; Mcburnie, Mary Ann

Clin Gastroenterol Hepatol. 2022 May 27.

PubMed abstract

Declining Colectomy Rates for Nonmalignant Colorectal Polyps in a Large, Ethnically Diverse, Community-based Population

Authors: Alam, Asim; Corley, Douglas A; Lee, Jeffrey K; Lee, Jeffrey K; et al.

Clin Transl Gastroenterol. 2022 05 01;13(5):e00477. Epub 2022-05-01.

PubMed abstract

American Society for Gastrointestinal Endoscopy guideline on screening for pancreatic cancer in individuals with genetic susceptibility: methodology and review of evidence

Authors: Calderwood, Audrey H; Naveed, Mariam; Qumseya, Bashar J; et al.

Gastrointest Endosc. 2022 05;95(5):827-854.e3. Epub 2022-02-16.

PubMed abstract

Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study

Authors: Archambault, Alexi N; Sakoda, Lori C; Lee, Jeffrey K; Corley, Douglas A; Hayes, Richard B; et al.

J Natl Cancer Inst. 2022 04 11;114(4):528-539.

PubMed abstract

Eosinophilic esophagitis: New molecules, better life?

Authors: Lam, Angela Y; Ma, Christopher; Lee, Jeffrey K; Bredenoord, Albert J

Curr Opin Pharmacol. 2022 04;63:102183. Epub 2022-02-15.

PubMed abstract

Too Good to Be True? Evaluation of Colonoscopy Sensitivity Assumptions Used in Policy Models

Authors: Rutter, Carolyn M; Nascimento de Lima, Pedro; Lee, Jeffrey K; Ozik, Jonathan

Cancer Epidemiol Biomarkers Prev. 2022 04 01;31(4):775-782.

PubMed abstract

Trends and Projections in National U.S. Healthcare Spending for Gastrointestinal Malignancies (1996-2030)

Authors: Stukalin, Igor; Ahmed, Newaz Shubidito; Fundytus, Adam M; Qian, Alexander S; Coward, Stephanie; Kaplan, Gilaad G; Hilsden, Robert J; Burak, Kelly W; Lee, Jeffrey K; Singh, Siddharth; Ma, Christopher

Gastroenterology. 2022 04;162(4):1098-1110.e2. Epub 2021-12-16.

PubMed abstract

Impact of the Affordable Care Act on Colorectal Cancer Incidence and Mortality

Authors: Lee, Catherine; Kushi, Lawrence H; Reed, Mary E; Eldridge, Elizabeth H; Lee, Jeffrey K; Zhang, Jie; Spiegelman, Donna

Am J Prev Med. 2022 03;62(3):387-394. Epub 2021-11-08.

PubMed abstract

Endoscopic Surveillance and Dysplasia Management in IBD: Plus Ça Change, Plus C’est la Même Chose

Authors: Velayos, Fernando S; Lee, Jeffrey K

Dig Dis Sci. 2022 01;67(1):81-84. Epub 2021-10-27.

PubMed abstract

Rising Early-Onset Colorectal Cancer Incidence is Not an Artifact of Increased Screening Colonoscopy Use in a Large, Diverse Healthcare System

Authors: Lee, Jeffrey K; Merchant, Sophie A; Jensen, Christopher D; Murphy, Caitlin C; Udaltsova, Natalia; Corley, Douglas A

Gastroenterology. 2022 01;162(1):325-327.e3. Epub 2021-09-20.

PubMed abstract

Program components and results from an organized colorectal cancer screening program using annual fecal immunochemical testing

Authors: Selby, Kevin; Jensen, Christopher D; Levin, Theodore R; Lee, Jeffrey K; Schottinger, Joanne E; Zhao, Wei K; Corley, Douglas A; Doubeni, Chyke A

Clin Gastroenterol Hepatol. 2022 01;20(1):145-152. Epub 2020-09-30.

PubMed abstract

Systematic review with meta-analysis: the prevalence of post-colonoscopy colorectal cancers using the World Endoscopy Organization nomenclature

Authors: Kang, James H-E; Evans, Nicole; Singh, Siddharth; Samadder, Niloy J; Lee, Jeffrey K

Aliment Pharmacol Ther. 2021 11;54(10):1232-1242. Epub 2021-09-29.

PubMed abstract

Simplifying ADR reporting – a worthy goal, but the devil is in the details

Authors: Lam, Angela Y; Lee, Jeffrey K; Levin, Theodore R

Clin Gastroenterol Hepatol. 2021 09;19(9):1793-1795. Epub 2021-04-24.

PubMed abstract

Risk stratification for colorectal cancer in individuals with subtypes of serrated polyps

Authors: Li, Dan; Doherty, Amanda R; Raju, Menaka; Liu, Liyan; Lei, Nan Ye; Amsden, Laura B; Lee, Jeffrey K; Levin, Theodore R; Corley, Douglas A; Herrinton, Lisa J

Gut. 2021 Aug 11.

PubMed abstract

ASGE guideline on the management of cholangitis

Authors: Buxbaum, James L; Lee, Jeffrey K; Wani, Sachin; et al.

Gastrointest Endosc. 2021 08;94(2):207-221.e14. Epub 2021-05-20.

PubMed abstract

ASGE guideline on the role of endoscopy in the management of malignant hilar obstruction

Authors: Qumseya, Bashar J; Lee, Jeffrey K; Wani, Sachin; et al.

Gastrointest Endosc. 2021 08;94(2):222-234.e22. Epub 2021-05-20.

PubMed abstract

Sugary truth of early-onset colorectal neoplasia – not so sweet after all

Authors: Lee, Jeffrey K; Burnett-Hartman, Andrea; Murphy, Caitlin C

Gastroenterology. 2021 07;161(1):27-29. Epub 2021-04-24.

PubMed abstract

The effect of using fecal testing after a negative sigmoidoscopy on the risk of death from colorectal cancer

Authors: Doubeni CA; Corley DA; Lee JK; Levin TR; Weiss NS; et al.

J Med Screen. 2021 06;28(2):140-147. Epub 2020-05-21.

PubMed abstract

Response to Li and Hopper

Authors: Thomas, Minta; Sakoda, Lori C; Lee, Jeffrey K; Corley, Douglas A; Hsu, Li; et al.

Am J Hum Genet. 2021 03 04;108(3):527-529.

PubMed abstract

Validated training tools are needed for assessing competency in colorectal endoscopic mucosal resection

Authors: Kidambi, Trilokesh D; Lee, Jeffrey K

Gastrointest Endosc. 2021 03;93(3):776-777.

PubMed abstract

An update on the epidemiology, molecular characterization, diagnosis, and screening strategies for early-onset colorectal cancer

Authors: Burnett-Hartman, Andrea N; Lee, Jeffrey K; Demb, Joshua; Gupta, Samir

Gastroenterology. 2021 03;160(4):1041-1049. Epub 2021-01-05.

PubMed abstract

When Should We Let Colorectal Cancer Screening Get Personal?

Authors: Lam, Angela Y; Lee, Jeffrey K

Am J Gastroenterol. 2021 02 01;116(2):278-279.

PubMed abstract

ASGE guideline on the role of endoscopy in the management of benign and malignant gastroduodenal obstruction

Authors: ASGE Standards of Practice Committee,; Pawa, Swati; (ASGE Standards of Practice Committee Chair, 2017-2020),; et al.

Gastrointest Endosc. 2021 02;93(2):309-322.e4. Epub 2020-11-07.

PubMed abstract

Influence of Telemedicine-First Intervention on Patient Visit Choice, Post-Visit Care, and Patient Satisfaction in Gastroenterology

Authors: Munroe, Craig A; Lin, Teresa Y; Rouillard, Smita; Fox, Jeffrey; Lee, Jeffrey K; Corley, Douglas A

Gastroenterology. 2021 02;160(3):929-931.e2. Epub 2020-10-16.

PubMed abstract

Urban-Rural Disparities and Temporal Trends in Peptic Ulcer Disease Epidemiology, Treatment, and Outcomes in the United States

Authors: Guo, Howard; Ma, Christopher; Ma, Christopher; et al.

Am J Gastroenterol. 2021 02 01;116(2):296-305.

PubMed abstract

Primary Care Provider Beliefs and Recommendations About Colorectal Cancer Screening in Four Healthcare Systems

Authors: Ghai NR; Lee JK; Corley DA; et al.

Cancer Prev Res (Phila). 2020 11;13(11):947-958. Epub 2020-07-15.

PubMed abstract

Early Screening of African Americans (45-50 Years Old) in a Fecal Immunochemical Test-based Colorectal Cancer Screening Program

Authors: Levin TR; Jensen CD; Chawla NM; Sakoda LC; Lee JK; Zhao WK; Landau MA; Herm A; Eby E; Quesenberry CP; Corley DA

Gastroenterology. 2020 11;159(5):1695-1704.e1. Epub 2020-07-20.

PubMed abstract

Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk

Authors: Thomas, Minta; Sakoda, Lori C; Lee, Jeffrey K; Corley, Douglas A; Hsu, Li; et al.

Am J Hum Genet. 2020 09 03;107(3):432-444. Epub 2020-08-05.

PubMed abstract

Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

Authors: Wang Z; Sitlani CM; CHARGE Gene-Lifestyle Interactions Working Group; et al.

Circ Genom Precis Med. 2020 08;13(4):e002772. Epub 2020-06-08.

PubMed abstract

Increased Risk of Colorectal Cancer in Individuals With a History of Serrated Polyps

Authors: Li D; Liu L; Fevrier HB; Alexeeff SE; Doherty AR; Raju M; Amsden LB; Lee JK; Levin TR; Corley DA; Herrinton LJ

Gastroenterology. 2020 08;159(2):502-511.e2. Epub 2020-04-08.

PubMed abstract

Proton Pump Inhibitor Use and Risk of Gastric, Colorectal, Liver, and Pancreatic Cancers in a Community-Based Population

Authors: Lee JK; Merchant SA; Schneider JL; Jensen CD; Fireman BH; Quesenberry CP; Corley DA

Am J Gastroenterol. 2020 05;115(5):706-715.

PubMed abstract

American Society for Gastrointestinal Endoscopy guideline on the role of endoscopy in familial adenomatous polyposis syndromes

Authors: Yang J; Lee JK; Samadder NJ; et al.

Gastrointest Endosc. 2020 05;91(5):963-982.e2. Epub 2020-03-10.

PubMed abstract

ASGE guideline on minimum staffing requirements for the performance of GI endoscopy

Authors: Jamil LH; Lee JK; Wani SB; et al.

Gastrointest Endosc. 2020 04;91(4):723-729.e17. Epub 2020-02-06.

PubMed abstract

Impact of observational training on endoscopic mucosal resection outcomes and competency for large colorectal polyps: single endoscopist experience

Authors: Lee JK; Kidambi TD; Kaltenbach T; Bhat YM; Shergill A; McQuaid KR; Terdiman JP; Soetikno RM

Endosc Int Open. 2020 Mar;8(3):E346-E353. Epub 2020-02-21.

PubMed abstract

Long-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population

Authors: Lee JK; Levin TR; Fireman BH; Quesenberry CP; Corley DA; et al.

Gastroenterology. 2020 03;158(4):884-894.e5. Epub 2019-10-04.

PubMed abstract

American Society for Gastrointestinal Endoscopy guideline on the role of endoscopy in the management of acute colonic pseudo-obstruction and colonic volvulus

Authors: Naveed M; Qumseya BJ; Wani SB; et al.

Gastrointest Endosc. 2020 02;91(2):228-235. Epub 2019-11-30.

PubMed abstract

ASGE guideline on the management of achalasia

Authors: Khashab MA; Lee JK; Wani S; et al.

Gastrointest Endosc. 2020 02;91(2):213-227.e6. Epub 2019-12-13.

PubMed abstract

Longitudinal Evolution of Markers of Mineral Metabolism in Patients With CKD: The Chronic Renal Insufficiency Cohort (CRIC) Study

Authors: Isakova T; Lo J; CRIC Study Investigators; et al.

Am J Kidney Dis. 2020 02;75(2):235-244. Epub 2019-10-23.

PubMed abstract

LIFE EXPECTANCY DISPARITIES AMONG ADULTS WITH HIV IN THE UNITED STATES AND CANADA: THE IMPACT OF A REDUCTION IN DRUG- AND ALCOHOL-RELATED DEATHS USING THE LIVES SAVED SIMULATION (LISSO) MODEL

Authors: Althoff KN; Silverberg MJ; North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) of IeDEA; et al.

Am J Epidemiol. 2019 12 31;188(12):2097-2109.

PubMed abstract

Effect of Sex, Age and Positivity Threshold on Fecal Immunochemical Test Accuracy: a Systematic Review and Meta-Analysis

Authors: Selby K; Levine EH; Doan C; Gies A; Brenner H; Quesenberry C; Lee JK; Corley DA

Gastroenterology. 2019 12;157(6):1494-1505. Epub 2019-08-22.

PubMed abstract

Morbidity and Mortality After Surgery for Nonmalignant Colorectal Polyps: A 10-Year Nationwide Analysis

Authors: Ma C; Teriaky A; Sheh S; Forbes N; Heitman SJ; Jue TL; Munroe CA; Jairath V; Corley DA; Lee JK

Am J Gastroenterol. 2019 11;114(11):1802-1810.

PubMed abstract

Immunotherapy-Associated Pseudomembranous Colitis

Authors: Kidambi TD; Chu P; Lee JK; Lin JL

Am J Gastroenterol. 2019 11;114(11):1708.

PubMed abstract

ASGE guideline on screening and surveillance of Barrett’s esophagus

Authors: ASGE STANDARDS OF PRACTICE COMMITTEE; Lee JK; ASGE Standards of Practice Committee Chair; et al.

Gastrointest Endosc. 2019 09;90(3):335-359.e2.

PubMed abstract

Colonoscopy Indication Algorithm Performance Across Diverse Health Care Systems in the PROSPR Consortium

Authors: Burnett-Hartman AN; Corley DA; Lee JK; Zheng Y; et al.

EGEMS (Wash DC). 2019 Aug 02;7(1):37. Epub 2019-08-02.

PubMed abstract

ASGE guideline on the role of endoscopy for bleeding from chronic radiation proctopathy

Authors: Lee JK; Wani SB; et al.

Gastrointest Endosc. 2019 08;90(2):171-182.e1. Epub 2019-06-22.

PubMed abstract

Low-Literacy Instructions Enable Successful Completion of Fecal Immunohistochemical Tests

Authors: Lam AY; Lee JK

Clin Gastroenterol Hepatol. 2019 08;17(9):1729-1731. Epub 2019-05-02.

PubMed abstract

A summary of the Fight Colorectal Cancer working meeting: exploring risk factors and etiology of sporadic early-age onset colorectal cancer

Authors: Dwyer AJ; Lee J; Ahnen D; et al.

Gastroenterology. 2019 08;157(2):280-288. Epub 2019-05-13.

PubMed abstract

Systematic review and meta-analysis: efficacy and safety of oral Janus kinase inhibitors for inflammatory bowel disease

Authors: Ma C; Lee JK; Mitra AR; Teriaky A; Choudhary D; Nguyen TM; Vande Casteele N; Khanna R; Panaccione R; Feagan BG; Jairath V

Aliment Pharmacol Ther. 2019 07;50(1):5-23. Epub 2019-05-23.

PubMed abstract

ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis

Authors: ASGE Standards of Practice Committee; Lee JK; Wani SB; et al.

Gastrointest Endosc. 2019 06;89(6):1075-1105.e15. Epub 2019-04-09.

PubMed abstract

Germline BRCA1 Deletion as Driver Mutation for Metastatic Urachal Adenocarcinoma in Patient Who Achieved Complete Response to Rucaparib

Authors: Seto T; Pujare D; Song MN; Lee J; Huber R; Sam D; Pan M

J Oncol Pract. 2019 05;15(5):293-295. Epub 2019-04-02.

PubMed abstract

Effects of Electronic Chromoendoscopy on Detection of Adenomas During Colonoscopy

Authors: Kidambi TD; Terdiman JP; El-Nachef N; Singh A; Kattah MG; Lee JK

Clin Gastroenterol Hepatol. 2019 03;17(4):701-708.e1. Epub 2018-06-20.

PubMed abstract

Strategies to Improve Follow-up After Positive Fecal Immunochemical Tests in a Community-Based Setting: A Mixed-Methods Study

Authors: Selby K; Jensen CD; Zhao WK; Lee JK; Slam A; Schottinger JE; Bacchetti P; Levin TR; Corley DA

Clin Transl Gastroenterol. 2019 02;10(2):e00010.

PubMed abstract

Long-term Risk of Colorectal Cancer and Related Deaths After a Colonoscopy With Normal Findings

Authors: Lee JK; Levin TR; Fireman BH; Quesenberry CP; Corley DA; et al.

JAMA Netw Open. 2019 09 04;2(9):e1911513. Epub 2019-09-04.

PubMed abstract

Colorectal Cancer Screening Participation Among Asian Americans Overall and Subgroups in an Integrated Health Care Setting with Organized Screening

Authors: Ghai NR; Jensen CD; Corley DA; Doubeni CA; Schottinger JE; Zauber AG; Lee AT; Contreras R; Levin TR; Lee JK; Quinn VP

Clin Transl Gastroenterol. 2018 09 21;9(9):186. Epub 2018-09-21.

PubMed abstract

Accurate Identification of Colonoscopy Quality and Polyp Findings Using Natural Language Processing

Authors: Lee JK; Jensen CD; Levin TR; Zauber AG; Doubeni CA; Zhao WK; Corley DA

J Clin Gastroenterol. 2019 01;53(1):e25-e30.

PubMed abstract

Novel variant of unknown significance in MUTYH in a patient with MUTYH-associated polyposis: a case to reclassify

Authors: Kidambi TD; Goldberg D; Nussbaum R; Blanco A; Umetsu SE; Terdiman JP; Lee JK

Clin J Gastroenterol. 2018 Dec;11(6):457-460. Epub 2018-05-15.

PubMed abstract

The Utility and Cross-Validation of a Composite Physical Activity Score in Relation to Cardiovascular Health Indicators: Coronary Artery Risk Development in Young Adults

Authors: Pettee Gabriel K; Pérez A; Jacobs DR; Lee J; Kohl HW; Sternfeld B

J Phys Act Health. 2018 11 01;15(11):847-856. Epub 2018-10-19.

PubMed abstract

Influence of Varying Quantitative Fecal Immunochemical Test Positivity Thresholds on Colorectal Cancer Detection: A Community-Based Cohort Study

Authors: Selby K; Lee JK; Levin TR; Corley DA; et al.

Ann Intern Med. 2018 10 02;169(7):439-447. Epub 2018-09-18.

PubMed abstract

Effects of Organized Colorectal Cancer Screening on Cancer Incidence and Mortality in a Large, Community-based Population

Authors: Levin TR; Corley DA; Lee JK; Quesenberry CP; Fireman BH; Doubeni CA; et al.

Gastroenterology. 2018 11;155(5):1383-1391.e5. Epub 2018-07-19.

PubMed abstract

Negative withdrawal time: simple and efficient

Authors: Kidambi TD; Terdiman JP; Lee JK

Gastrointest Endosc. 2018 10;88(4):781.

PubMed abstract

Yield of Colonoscopy After a Positive Result From a Fecal Immunochemical Test OC-Light.

Authors: Alsayid, Muhammad M; Singh, Maneesh H MH; Issaka, Rachel R; Laleau, Victoria V; Day, Lukejohn L; Lee, Jeffrey J; Allison, James J; Somsouk, Ma M

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2018 Oct ;16(10):1593-1597.e1. Epub 2018-04-13.

PubMed abstract

Development and validation of the SIMPLE endoscopic classification of diminutive and small colorectal polyps.

Authors: Iacucci, Marietta M; Trovato, Cristina C; Daperno, Marco M; Akinola, Oluseyi O; Greenwald, David D; Gross, Seth A SA; Hoffman, Arthur A; Lee, Jeffrey J; Lethebe, Brendan C BC; Lowerison, Mark M; Nayor, Jennifer J; Neumann, Helmut H; Rath, Timo T; Sanduleanu, Silvia S; Sharma, Prateek P; Kiesslich, Ralf R; Ghosh, Subrata S; Saltzman, John R JR;

Endoscopy. 2018 Aug ;50(8):779-789. Epub 2018-03-23.

PubMed abstract

An Unexpected Finding During Colonoscopy: Pinworms.

Authors: Kidambi, Trilokesh D TD; Lee, Jeffrey K JK

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2018 Jan ;16(1):e4. Epub --.

PubMed abstract

Interventions to Improve Follow-up of Positive Results on Fecal Blood Tests: A Systematic Review

Authors: Selby K; Baumgartner C; Levin TR; Doubeni CA; Zauber AG; Schottinger J; Jensen CD; Lee JK; Corley DA

Ann Intern Med. 2017 Oct 17;167(8):565-575. Epub 2017-10-10.

PubMed abstract

Endoscopy is of low yield in the identification of gastrointestinal neoplasia in patients with dermatomyositis: A cross-sectional study.

Authors: Kidambi, Trilokesh D TD; Schmajuk, Gabriela G; Gross, Andrew J AJ; Ostroff, James W JW; Terdiman, Jonathan P JP; Lee, Jeffrey K JK

World journal of gastroenterology. 2017 Jul 14;23(26):4788-4795. Epub --.

PubMed abstract

Surveillance for One or Two Small Adenomas: Low Risk Is Really Low Risk.

Authors: Lee, Jeffrey K JK; Lieberman, David D

Gastroenterology. 2017 06 ;152(8):1819-1821. Epub 2017-04-28.

PubMed abstract

Association Between Time to Colonoscopy After a Positive Fecal Test Result and Risk of Colorectal Cancer and Cancer Stage at Diagnosis

Authors: Corley DA; Lee JK; Quesenberry CP; Fireman BH; Levin TR; et al.

JAMA. 2017 Apr 25;317(16):1631-1641.

PubMed abstract

Recommendations on Fecal Immunochemical Testing to Screen for Colorectal Neoplasia: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer

Authors: Robertson DJ; Lee JK; Boland CR; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Lieberman D; Levin TR; Rex DK

Am J Gastroenterol. 2017 Jan;112(1):37-53. Epub 2016-10-18.

PubMed abstract

Inhibition of Escherichia coli CTP Synthetase by NADH and Other Nicotinamides and Their Mutual Interactions with CTP and GTP

Authors: Habrian C; Chandrasekhara A; Shahrvini B; Hua B; Lee J; Jesinghaus R; Barry R; Gitai Z; Kollman J; Baldwin EP

Biochemistry. 2016 Oct 04;55(39):5554-5565. Epub 2016-09-19.

PubMed abstract

Fecal Immunochemical Test Program Performance Over 4 Rounds of Annual Screening: A Retrospective Cohort Study

Authors: Jensen CD; Corley DA; Lee JK; Quesenberry CP; Levin TR; Mysliwiec PA; et al.

Ann Intern Med. 2016 Apr 5;164(7):456-63. Epub 2016-01-26.

PubMed abstract

Factors Influencing Variation in Physician Adenoma Detection Rates: a Theory-Based Approach for Performance Improvement

Authors: Atkins L; Hunkeler EM; Jensen CD; Michie S; Lee JK; Doubeni CA; Zauber AG; Levin TR; Quinn VP; Corley DA

Gastrointest Endosc. 2016 Mar;83(3):617-26.e2. Epub 2015-09-11.

PubMed abstract

What makes a “good” colonoscopy quality indicator?

Authors: Lee JK; Corley DA

Gastrointest Endosc. 2016 Jan;83(1):179-81.

PubMed abstract

Adjusting for Patient Demographics Has Minimal Effects on Rates of Adenoma Detection in a Large, Community-based Setting

Authors: Jensen CD; Levin TR; Lee JK; Fireman BH; Quesenberry CP; Corley DA; et al.

Clin Gastroenterol Hepatol. 2015 Apr;13(4):739-46. Epub 2014-10-25.

PubMed abstract

Development and validation of an algorithm for classifying colonoscopy indication

Authors: Lee JK; Jensen CD; Lee A; Doubeni CA; Zauber AG; Levin TR; Zhao WK; Corley DA

Gastrointest Endosc. 2015 Mar;81(3):575-582.e4. Epub 2015-01-08.

PubMed abstract

Importance of determining indication for colonoscopy: implications for practice and policy original

Authors: Singal AG; Gupta S; Lee J; Halm EA; Rutter CM; Corley D; Inadomi J

Clin Gastroenterol Hepatol. 2014 Dec;12(12):1958-63.e1-3.

PubMed abstract

Multitarget stool DNA testing for colorectal-cancer screening.

Authors: Lee, Jeffrey K JK; Terdiman, Jonathan P JP; Corley, Douglas A DA

The New England journal of medicine. 2014 07 10;371(2):186. Epub --.

PubMed abstract

Adenoma detection rate and risk of colorectal cancer and death

Authors: Corley DA; Lee JK; Fireman BH; Levin TR; Quesenberry CP; et al.

N Engl J Med. 2014 Apr 3;370(14):1298-306.

PubMed abstract

Accuracy of fecal immunochemical tests for colorectal cancer: systematic review and meta-analysis

Authors: Lee JK; Liles EG; Bent S; Levin TR; Corley DA

Ann Intern Med. 2014 Feb 4;160(3):171.

PubMed abstract

Recurrence of subsquamous dysplasia and carcinoma after successful endoscopic and radiofrequency ablation therapy for dysplastic Barrett’s esophagus.

Authors: Lee, J K JK; Cameron, R G RG; Binmoeller, K F KF; Shah, J N JN; Shergill, A A; Garcia-Kennedy, R R; Bhat, Y M YM

Endoscopy. 2013 Jul ;45(7):571-4. Epub 2013-04-16.

PubMed abstract

The Road Ahead: What if Gastroenterologists Were Accountable for Preventing Colorectal Cancer?

Authors: Lee JK; Levin TR; Corley DA

Clin Gastroenterol Hepatol. 2013 Mar;11(3):204-7.

PubMed abstract

Association between serum interleukin-6 concentrations and mortality in older adults: the Rancho Bernardo study.

Authors: Lee, Jeffrey K JK; Bettencourt, Ricki R; Brenner, David D; Le, Thuy-Anh TA; Barrett-Connor, Elizabeth E; Loomba, Rohit R

PloS one. 2012 ;7(4):e34218. Epub 2012-04-13.

PubMed abstract

Cost-effectiveness of a mailed educational reminder to increase colorectal cancer screening.

Authors: Lee, Jeffrey K JK; Groessl, Erik J EJ; Ganiats, Theodore G TG; Ho, Samuel B SB

BMC gastroenterology. 2011 Aug 25;11():93. Epub 2011-08-25.

PubMed abstract

Molecular Prognostic and Predictive Markers in Colorectal Cancer: Current Status.

Authors: Lee, Jeffrey K JK; Chan, Andrew T AT

Current colorectal cancer reports. 2011 Jun 01;7(2):136-144. Epub --.

PubMed abstract

Evidence for an hMSH3 defect in familial hamartomatous polyps.

Authors: Huang, Sherry C SC; Lee, Jeffrey K JK; Smith, E Julieta EJ; Doctolero, Ryan T RT; Tajima, Akihiro A; Beck, Stayce E SE; Weidner, Noel N; Carethers, John M JM

Cancer. 2011 Feb 01;117(3):492-500. Epub 2010-09-15.

PubMed abstract

Achalasia, alcohol-stasis, and acute necrotizing esophagitis: connecting the dots.

Authors: Lee, Jeffrey K JK; Bhargava, Valmik V; Mittal, Ravinder K RK; Ghosh, Pradipta P

Digestive diseases and sciences. 2011 Feb ;56(2):612-4. Epub 2010-06-16.

PubMed abstract

Activin signaling in microsatellite stable colon cancers is disrupted by a combination of genetic and epigenetic mechanisms.

Authors: Jung, Barbara B; Gomez, Jessica J; Chau, Eddy E; Cabral, Jennifer J; Lee, Jeffrey K JK; Anselm, Aimee A; Slowik, Przemyslaw P; Ream-Robinson, Deena D; Messer, Karen K; Sporn, Judith J; Shin, Sung K SK; Boland, C Richard CR; Goel, Ajay A; Carethers, John M JM

PloS one. 2009 Dec 14;4(12):e8308. Epub 2009-12-14.

PubMed abstract

Improving fecal occult blood testing compliance using a mailed educational reminder.

Authors: Lee, Jeffrey K JK; Reis, Veronica V; Liu, Shanglei S; Conn, Lorraine L; Groessl, Erik J EJ; Ganiats, Theodore G TG; Ho, Samuel B SB

Journal of general internal medicine. 2009 Nov ;24(11):1192-7. Epub 2009-09-23.

PubMed abstract

ArterioVenous Malformation within Jejunal Diverticulum: an unusual cause of massive gastrointestinal bleeding.

Authors: Lee, Jeffrey K JK; Carethers, John M JM; Ghosh, Pradipta P

Gastroenterology research and practice. 2009 ;2009():384506. Epub 2009-09-10.

PubMed abstract

The inflammatory response in transgastric surgery: gastric content leak leads to localized inflammatory response and higher adhesive disease.

Authors: Ramamoorthy, Sonia L SL; Lee, Jeffrey K JK; Luo, Linda L; Mintz, Yoav Y; Cullen, John J; Easter, David W DW; Savu, Michelle K MK; Chock, Alana A; Carethers, John J; Horgan, Santiago S; Talamini, Mark A MA

Surgical endoscopy. 2010 Mar ;24(3):531-5. Epub 2009-08-18.

PubMed abstract

Generalized megaviscera of lupus: refractory intestinal pseudo-obstruction, ureterohydronephrosis and megacholedochus.

Authors: Park, Frederick-D FD; Lee, Jeffrey-K JK; Madduri, Ganga-D GD; Ghosh, Pradipta P

World journal of gastroenterology. 2009 Jul 28;15(28):3555-9. Epub --.

PubMed abstract

The impact of proton-pump inhibitors on intraperitoneal sepsis: a word of caution for transgastric NOTES procedures.

Authors: Ramamoorthy, Sonia L SL; Lee, Jeffrey K JK; Mintz, Yoav Y; Cullen, John J; Savu, Michelle K MK; Easter, David W DW; Chock, Alana A; Mittal, Ravi R; Horgan, Santiago S; Talamini, Mark A MA

Surgical endoscopy. 2010 Jan ;24(1):16-20. Epub 2009-06-24.

PubMed abstract

Endoscopy is accurate, safe, and effective in the assessment and management of complications following gastric bypass surgery.

Authors: Lee, Jeffrey K JK; Van Dam, Jacques J; Morton, John M JM; Curet, Myriam M; Banerjee, Subhas S

The American journal of gastroenterology. 2009 Mar ;104(3):575-82; quiz 583. Epub 2009-02-03.

PubMed abstract

Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair.

Authors: Chung, Heekyung H; Young, Dennis J DJ; Lopez, Claudia G CG; Le, Thuy-Anh T TA; Lee, Jeffrey K JK; Ream-Robinson, Deena D; Huang, Sherry C SC; Carethers, John M JM

PloS one. 2008 ;3(10):e3463. Epub 2008-10-21.

PubMed abstract

Evidence for colorectal sarcomatoid carcinoma arising from tubulovillous adenoma.

Authors: Lee, Jeffrey-K JK; Ghosh, Pradipta P; McWhorter, Valerie V; Payne, Misty M; Olson, Ryan R; Krinsky, Mary-L ML; Ramamoorthy, Sonia S; Carethers, John-M JM

World journal of gastroenterology. 2008 Jul 21;14(27):4389-94. Epub --.

PubMed abstract

Nonmetastatic cancer of the colon associated with pyogenic liver abscess.

Authors: Lee, Jeffrey K JK; Kum, Jennifer J; Ghosh, Pradipta P

The American journal of gastroenterology. 2008 Mar ;103(3):798-9. Epub --.

PubMed abstract

Education and imaging. Gastrointestinal: glycogenic acanthosis.

Authors: Lee, J K JK; Kum, J J; Ghosh, P P

Journal of gastroenterology and hepatology. 2007 Sep ;22(9):1550. Epub --.

PubMed abstract

Incidental finding of metastatic papillary thyroid carcinoma in a patient with primary hyperparathyroidism.

Authors: Lee, Jeffrey K JK; Obrzut, Sebastian L SL; Yi, Eunhee S ES; Deftos, Leonard J LJ; Bouvet, Michael M

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. ;13(4):380-3. Epub --.

PubMed abstract

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