Theodore R. Levin, MD

theodore.levin@kp.org

Kaiser Permanente Researcher Profiles

Levin, Theodore R.

Theodore R. Levin, MD, is a Research Scientist at the Kaiser Permanente Northern California Division of Research and Associate Director for the Cancer section. Dr. Levin is also an Associate Professor of Health System Science at the Kaiser Permanente School of Medicine and a Staff Gastroenterologist at the Kaiser Permanente Walnut Creek Medical Center. He is the Clinical Lead for Colorectal Cancer Screening and Assistant Chair of Gastroenterology for The Permanente Medical Group. Dr. Levin’s research interests include health services and outcomes research in gastroenterology and population health. Particular areas of interest are colorectal cancer screening with colonoscopy fecal occult blood tests, and newer DNA-based technologies.

Current Positions

  • Research Scientist III, Division of Research, Kaiser Permanente Northern California
  • Staff Gastroenterologist, Kaiser Permanente Medical Center, Walnut Creek
  • Associate Professor of Health System Science, Kaiser Permanente School of Medicine

Section Affiliations

Primary Research Interests

  • Health services and outcomes research related to colorectal cancer and endoscopy.
  • Care delivery research in population health.

Studies

Crossing the Quality Chasm for Men under age 55 (CQC55)

The goal of this research is to improve hypertension control, diabetes control, and colorectal cancer screening rates among younger men within KPNC. We will start by conducting focus groups with Black, Filipino, and Latino men aged 40-55 to identify barriers and facilitators to chronic disease management and age-appropriate cancer screening. During years 3 and 4, we will use focus group findings to develop multi-modal tailored messaging strategies, or physician and staff communication training. We will evaluate these interventions in trials, assessing the impact on HTN control, T2DM control, and CRC screening rates among younger Black, Filipino, and Latino men.

Investigator: Levin, Theodore

Funder: TPMG Physician Researcher Program

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of the Efficacy, Safety, and Tolerability of a Single Oral Administration of CP101 for the Prevention of Recurrent Clostridioides difficile Infection (PRISM4)

Phase 3 trial will evaluate the efficacy of CP101 treatment relative to placebo in adults with previously treated recurrent Clostridioides difficile infection (CDI) and evaluate the safety and tolerability of CP101 treatment compared to placebo in adults with previously treated recurrent CDI.

Investigator: Levin, Theodore

Funder: Finch Research and Development, LLC

Comparative Effectiveness Trial of Non-invasive vs. Invasive Strategies (FIT vs Colonoscopy) for Older Adults with a History of Pre-neoplastic Colon Polyps

This comparative effectiveness trial will evaluate detection of significant neoplasia between the strategies of low threshold annual FIT vs. colonoscopy for older adults with a history of colon polyps. We will investigate whether the FIT strategy is non-inferior to colonoscopy in detecting CRC and advanced colorectal neoplasia over 5 years of follow-up and whether fewer colonoscopies are needed to detect CRC using FIT vs. colonoscopy. We will also compare complication rates and patient experience between the FIT and colonoscopy strategies to see whether those in the FIT strategy will have less complications compared to the colonoscopy strategy and whether the FIT strategy will be more convenient and tolerable compared to the colonoscopy strategy.

Investigator: Levin, Theodore

Funder: Patient-Centered Outcomes Research Institute

Evaluating Acceptance and Screening Yield for Early Colorectal Cancer Screening: (EASY Early CRC)

Three national guideline groups now recommend that all adults start colorectal cancer (CRC) screening at age 45. Before 2018, some guideline groups only recommended African Americans begin CRC screening at age 45. There is currently no empirical evidence of the value of screening before age 50. The only evidence comes from modeling studies and observational data collected in cancer registries, such as SEER. This project will evaluate the acceptance, uptake, and yield of mailed FIT screening among KP members in Northern California, Southern California, Washington, and Colorado. The findings will help National Guideline Directors make a recommendation to the Permanente Medical Groups and the Kaiser Foundation Health Plan about starting CRC screening at age 45.

Investigator: Levin, Theodore

Funder: Garfield Memorial Fund

PREEMPT CRC: Prevention of Colorectal Cancer Through Multiomics Blood Testing

The primary objectives of this study are to determine the sensitivity and specificity of Freenome’s test for colorectal adenocarcinoma, using screening CS with histopathology as the reference method.

Investigator: Levin, Theodore

Funder: Freenome Holdings, Inc

Non-alcoholic Fatty Liver Disease Prevalence and Associated Mortality (NAFLD PAM)

This study will investigate the incremental yield of using radiology imaging report information to diagnose non-alcoholic fatty liver disease (NAFLD) compared to International Classification of Disease, Ninth/Tenth Revision, Clinical Modification diagnoses alone in adult Kaiser Permanente Northern California members between 2009-2018, and whether the use of the Dallas Steatosis Index identifies additional individuals at high risk for NAFLD. The study will also and look at whether patients with NAFLD are at increased risk for all-cause mortality compared to the general population.

Investigator: Levin, Theodore

Funder: Northern California Community Benefit Programs

COVID-19 Pandemic: Impact on Colorectal Cancer Screening and Adenoma Surveillance Outcomes (PICASO)

The goal of this project is to evaluate the impact of the COVID pandemic on colorectal cancer screening and surveillance activities, and the impact on outcomes such as colorectal cancer incidence and stage.

Investigator: Levin, Theodore

Funder: Garfield Memorial Fund

PREDICT PCCC: PREDICTing Post Colonoscopy Colorectal Cancer

We are using post-polypectomy surveillance, an increasingly common indication for colonoscopy in clinical practice at TPMG and across the United States, as a model for how we might risk-stratify patients for care. Patients and physicians desire more precise estimates of risk for cancer after the removal of benign colorectal polyps to guide when they should have repeat surveillance with colonoscopy. We aim to evaluate a traditional risk prediction model compared with a deep learning model to improve the accuracy of risk scoring for post-colonoscopy colorectal cancer and guide personalized care

Investigator: Levin, Theodore

Funder: The Permanente Medical Group

PRISM-EXT: An Open-Label Extension of CP101 Trials Evaluating Oral Full-Spectrum Microbiota (CP101) in Subjects with Recurrence of Clostridium difficile Infection

This study evaluates the safety and efficacy in reducing recurrence of Clostridium difficile infection in adults who had a recurrence within 8 weeks of receiving CP101 or placebo in PRISM3. Subjects who are experiencing recurrent Clostridium difficile infection will undergo screening procedures. Subjects who meet eligibility criteria will be eligible to be enrolled in the extension study and administered CP101.

Investigator: Levin, Theodore

Funder: Finch Research and Development, LLC

A Multicenter Phase 2 Study of the Efficacy, Safety, and Tolerability of Oral Full-Spectrum Microbiota (CP101) in Subjects with Recurrence of Clostridium Difficile Infection

The objectives of this Phase 2 study are to evaluate the safety and tolerability of CP101 treatment compared to placebo in adults with previously treated, recurrent Clostridium difficile infection, and to evaluate the efficacy of CP101 treatment relative to placebo in adults with previously treated, recurrent Clostridium difficile infection.

Investigator: Levin, Theodore

Funder: Finch Research and Development, LLC

Outreach for Colorectal Cancer Screening in African Americans Aged 45 to 49

This study aims to 1) evaluate uptake of fecal immunochemical testing among African Americans aged 45 to 49 who receive outreach for such testing by mail, 2) examine the yield of screening results, including advanced adenomas and colon cancers, and 3) describe adverse events of screening among this population and compare them to those seen in people aged 50 to 55.

Investigator: Levin, Theodore

Funder: The Permanente Medical Group

Publications

Quality indicators for colonoscopy

Authors: Rex, Douglas K;Levin, Theodore R;Shaheen, Nicholas J;et al.

Gastrointest Endosc. 2024 Sep;100(3):352-381. Epub 2024-08-21.

PubMed abstract

Quality indicators for colonoscopy

Authors: Rex, Douglas K;Levin, Theodore R;Shaheen, Nicholas J;et al.

Am J Gastroenterol. 2024 Aug 21.

PubMed abstract

Fecal Immunochemical Test Screening and Risk of Colorectal Cancer Death

Authors: Doubeni, Chyke A;Levin, Theodore R;Schottinger, Joanne E;et al.

JAMA Netw Open. 2024 Jul 01;7(7):e2423671. Epub 2024-07-01.

PubMed abstract

Hepatocellular Carcinoma in Metabolic Dysfunction-Associated Steatotic Liver Disease

Authors: Rodriguez, Luis A;Schmittdiel, Julie A;Liu, Liyan;Macdonald, Brock A;Balasubramanian, Sreepriya;Chai, Krisna P;Seo, Suk I;Mukhtar, Nizar;Levin, Theodore R;Saxena, Varun

JAMA Netw Open. 2024 Jul 01;7(7):e2421019. Epub 2024-07-01.

PubMed abstract

Patterns of Care Following a Positive Fecal Blood Test for Colorectal Cancer: A Mixed Methods Study

Authors: Hahn, Erin E;Levin, Theodore R;Levin, Theodore R;et al.

J Gen Intern Med. 2024 May 21.

PubMed abstract

Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults

Authors: Shaukat, Aasma;Levin, Theodore R;Church, Timothy R

Ann Intern Med. 2024 Apr;177(4):542-543.

PubMed abstract

Colorectal Cancer Screening After Sequential Outreach Components in a Demographically Diverse Cohort

Authors: Podmore, Clara;Selby, Kevin;Jensen, Christopher D;Zhao, Wei K;Weiss, Noel S;Levin, Theodore R;Schottinger, Joanne;Doubeni, Chyke A;Corley, Douglas A

JAMA Netw Open. 2024 Apr 01;7(4):e245295. Epub 2024-04-01.

PubMed abstract

Surveillance Colonoscopy Findings in Older Adults With a History of Colorectal Adenomas

Authors: Lee, Jeffrey K;Levin, Theodore R;Corley, Douglas A;Corley, Douglas A;et al.

JAMA Netw Open. 2024 Apr 01;7(4):e244611. Epub 2024-04-01.

PubMed abstract

Predicting Risk of Colorectal Cancer After Adenoma Removal in a Large, Community-based Setting

Authors: Lee, Jeffrey K;Levin, Theodore R;Corley, Douglas A;Corley, Douglas A;et al.

Am J Gastroenterol. 2024 Feb 14.

PubMed abstract

Unsatisfactory Fecal Immunochemical Tests for Colorectal Cancer Screening: Prevalence, Reasons, and Subsequent Testing

Authors: Liu, Po-Hong;Levin, Theodore R;Halm, Ethan A;et al.

Cancer Epidemiol Biomarkers Prev. 2024 Feb 06;33(2):215-223.

PubMed abstract

Randomized trial of patient outreach approaches to de-implement outdated colonoscopy surveillance intervals

Authors: Lee, Jeffrey K;Velayos, Fernando S;Quesenberry, Charles P;Corley, Douglas A;Levin, Theodore R;Levin, Theodore R;et al.

Clin Gastroenterol Hepatol. 2024 Jan 06.

PubMed abstract

Development and External Validation of a Prediction Model for Colorectal Cancer Among Patients Awaiting Surveillance Colonoscopy Following Polypectomy

Authors: Levin, Theodore R;Jensen, Christopher D;Marks, Amy R;Schlessinger, David;Liu, Vincent;Udaltsova, Natalia;Badalov, Jessica;Layefsky, Evan;Corley, Douglas A;Nugent, Joshua R;Lee, Jeffrey K

Gastro Hep Adv. 2024;3(5):671-683. Epub 2024-03-15.

PubMed abstract

Impact of a scalable training program on the quality of colonoscopy performance and risk of post-colonoscopy colorectal cancer

Authors: Corley, Douglas A;Jensen, Christopher D;Lee, Jeffrey K;Contreras, Richard;Fireman, Bruce H;Quesenberry, Charles P;et al.

Gastrointest Endosc. 2023 Oct;98(4):609-617. Epub 2023-04-23.

PubMed abstract

Transportation barriers and endoscopic procedures: barriers, legal challenges, and strategies for GI endoscopy units

Authors: American Society for Gastrointestinal Endoscopy Quality Assurance in Endoscopy Committee,;Kwok, Karl;Levin, Theodore R;Dominitz, Jason A;Panganamamula, Kashyap;Feld, Andrew D;Bardall, Bruce;Newbury, Kara;Day, Lukejohn W

Gastrointest Endosc. 2023 Oct;98(4):475-481. Epub 2023-08-24.

PubMed abstract

An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles

Authors: Bresalier, Robert S;Levin, Bernard;Members of the World Endoscopy Colorectal Cancer Screening New Test Evaluation Expert Working Group,;et al.

Gut. 2023 Oct;72(10):1904-1918. Epub 2023-07-18.

PubMed abstract

Does Screening Colonoscopy Have a Future in the United States?

Authors: Rex, Douglas K;Ladabaum, Uri;Anderson, Joseph C;Shaukat, Aasma;Butterly, Lynn F;Dominitz, Jason A;Kaltenbach, Tonya;Levin, Theodore R;Hassan, Cesare

Clin Gastroenterol Hepatol. 2023 Aug 02.

PubMed abstract

Risk of colorectal cancer and colorectal cancer mortality beginning one year after a negative fecal occult blood test, among screen-eligible 76-85-year-olds

Authors: Dalmat, Ronit R;Burnett-Hartman, Andrea N;Halm, Ethan A;Chubak, Jessica;et al.

Cancer Epidemiol Biomarkers Prev. 2023 Jul 14.

PubMed abstract

Risk of colorectal cancer and colorectal cancer mortality beginning ten years after a negative colonoscopy, among screen-eligible adults 76-85 years old

Authors: Dalmat, Ronit R; Corley, Douglas A; Levin, Theodore R; Chubak, Jessica; et al.

Cancer Epidemiol Biomarkers Prev. 2023 Jan 09;32(1):37-45.

PubMed abstract

Impact and recovery from COVID-19-related disruptions in colorectal cancer screening and care in the US: A scenario analysis

Authors: van den Puttelaar, Rosita; Lansdorp-Vogelaar, Iris; Hahn, Anne I; Rutter, Carolyn M; Levin, Theodore R; Zauber, Ann G; Meester, Reinier G S

Cancer Epidemiol Biomarkers Prev. 2023 Jan 09;32(1):22-29.

PubMed abstract

Impact of the COVID-19 pandemic on fecal immunochemical testing, colonoscopy services, and colorectal neoplasia detection in a large United States community-based population

Authors: Lee, Jeffrey K; Li, Dan; Corley, Douglas A; Levin, Theodore R; et al.

Gastroenterology. 2022 09;163(3):723-731.e6. Epub 2022-05-14.

PubMed abstract

Current and future colorectal cancer screening strategies

Authors: Shaukat, Aasma; Levin, Theodore R

Nat Rev Gastroenterol Hepatol. 2022 08;19(8):521-531. Epub 2022-05-03.

PubMed abstract

Association between Improved Colorectal Screening and Racial Disparities

Authors: Doubeni, Chyke A; Corley, Douglas A; Zhao, Wei; Lau, YanKwan; Jensen, Christopher D; Levin, Theodore R

N Engl J Med. 2022 02 24;386(8):796-798.

PubMed abstract

Program components and results from an organized colorectal cancer screening program using annual fecal immunochemical testing

Authors: Selby, Kevin; Jensen, Christopher D; Levin, Theodore R; Lee, Jeffrey K; Schottinger, Joanne E; Zhao, Wei K; Corley, Douglas A; Doubeni, Chyke A

Clin Gastroenterol Hepatol. 2022 01;20(1):145-152. Epub 2020-09-30.

PubMed abstract

Simplifying ADR reporting – a worthy goal, but the devil is in the details

Authors: Lam, Angela Y; Lee, Jeffrey K; Levin, Theodore R

Clin Gastroenterol Hepatol. 2021 09;19(9):1793-1795. Epub 2021-04-24.

PubMed abstract

Risk stratification for colorectal cancer in individuals with subtypes of serrated polyps

Authors: Li, Dan; Doherty, Amanda R; Raju, Menaka; Liu, Liyan; Lei, Nan Ye; Amsden, Laura B; Lee, Jeffrey K; Levin, Theodore R; Corley, Douglas A; Herrinton, Lisa J

Gut. 2021 Aug 11.

PubMed abstract

The effect of using fecal testing after a negative sigmoidoscopy on the risk of death from colorectal cancer

Authors: Doubeni CA; Corley DA; Lee JK; Levin TR; Weiss NS; et al.

J Med Screen. 2021 06;28(2):140-147. Epub 2020-05-21.

PubMed abstract

Heterogeneity in colorectal cancer incidence among people recommended 3-yearly surveillance post-polypectomy: a validation study

Authors: Robbins, Emma C; Levin, Theodore; Cross, Amanda J; et al.

Endoscopy. 2021 Apr;53(4):402-410. Epub 2020-08-19.

PubMed abstract

Disparities in Preventable Mortality from Colorectal Cancer: are they the result of structural racism?

Authors: Doubeni, Chyke A; Selby, Kevin; Levin, Theodore R

Gastroenterology. 2021 03;160(4):1022-1025. Epub 2021-01-05.

PubMed abstract

Colorectal cancer screening in the COVID-19 era

Authors: Dekker, Evelien; Chiu, Han-Mo; Lansdorp-Vogelaar, Iris; WEO Colorectal Cancer Screening Committee,

Gastroenterology. 2020 Dec;159(6):1998-2003. Epub 2020-09-20.

PubMed abstract

Early Screening of African Americans (45-50 Years Old) in a Fecal Immunochemical Test-based Colorectal Cancer Screening Program

Authors: Levin TR; Jensen CD; Chawla NM; Sakoda LC; Lee JK; Zhao WK; Landau MA; Herm A; Eby E; Quesenberry CP; Corley DA

Gastroenterology. 2020 11;159(5):1695-1704.e1. Epub 2020-07-20.

PubMed abstract

Increased Risk of Colorectal Cancer in Individuals With a History of Serrated Polyps

Authors: Li D; Liu L; Fevrier HB; Alexeeff SE; Doherty AR; Raju M; Amsden LB; Lee JK; Levin TR; Corley DA; Herrinton LJ

Gastroenterology. 2020 08;159(2):502-511.e2. Epub 2020-04-08.

PubMed abstract

Mailed fecal immunochemical test outreach for colorectal cancer screening: Summary of a Centers for Disease Control and Prevention-sponsored summit

Authors: Gupta S; Levin TR; Pignone M; et al.

CA Cancer J Clin. 2020 07;70(4):283-298. Epub 2020-06-25.

PubMed abstract

Validation of an Algorithm to Identify Patients at Risk for Colorectal Cancer Based on Laboratory Test and Demographic Data in Diverse, Community-Based Population

Authors: Schneider J; Layefsky E; Udaltsova N; Levin TR; Corley DA

Clin Gastroenterol Hepatol. 2020 Apr 29.

PubMed abstract

What Is Organized Screening and What Is Its Value?

Authors: Dominitz JA; Levin TR

Gastrointest Endosc Clin N Am. 2020 Jul;30(3):393-411. Epub 2020-04-16.

PubMed abstract

Long-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population

Authors: Lee JK; Levin TR; Fireman BH; Quesenberry CP; Corley DA; et al.

Gastroenterology. 2020 03;158(4):884-894.e5. Epub 2019-10-04.

PubMed abstract

Comparison of Universal Versus Age-Restricted Screening of Colorectal Tumors for Lynch Syndrome Using Mismatch Repair Immunohistochemistry: A Cohort Study

Authors: Li D; Levin TR; Corley DA; Bergoffen J; et al.

Ann Intern Med. 2019 07 02;171(1):19-26. Epub 2019-06-11.

PubMed abstract

Strategies to Improve Follow-up After Positive Fecal Immunochemical Tests in a Community-Based Setting: A Mixed-Methods Study

Authors: Selby K; Jensen CD; Zhao WK; Lee JK; Slam A; Schottinger JE; Bacchetti P; Levin TR; Corley DA

Clin Transl Gastroenterol. 2019 02;10(2):e00010.

PubMed abstract

Long-term Risk of Colorectal Cancer and Related Deaths After a Colonoscopy With Normal Findings

Authors: Lee JK; Levin TR; Fireman BH; Quesenberry CP; Corley DA; et al.

JAMA Netw Open. 2019 09 04;2(9):e1911513. Epub 2019-09-04.

PubMed abstract

Balancing Adherence and Expense: The Cost-Effectiveness of Two-Sample vs One-Sample Fecal Immunochemical Test

Authors: Smith DH; O'Keeffe Rosetti M; Mosen DM; Rosales AG; Keast E; Perrin N; Feldstein AC; Levin TR; Liles EG

Popul Health Manag. 2019 02;22(1):83-89. Epub 2018-06-21.

PubMed abstract

Modifiable Failures in the Colorectal Cancer Screening Process and Their Association with Risk of Death

Authors: Doubeni CA; Levin TR; Corley DA; et al.

Gastroenterology. 2019 01;156(1):63-74.e6. Epub 2018-09-27.

PubMed abstract

Colorectal Cancer Screening Participation Among Asian Americans Overall and Subgroups in an Integrated Health Care Setting with Organized Screening

Authors: Ghai NR; Jensen CD; Corley DA; Doubeni CA; Schottinger JE; Zauber AG; Lee AT; Contreras R; Levin TR; Lee JK; Quinn VP

Clin Transl Gastroenterol. 2018 09 21;9(9):186. Epub 2018-09-21.

PubMed abstract

Index colonoscopy-related risk factors for postcolonoscopy colorectal cancers

Authors: Tollivoro TA; Levin TR; Fireman B; Quesenberry CP; Corley DA; et al.

Gastrointest Endosc. 2019 01;89(1):168-176.e3. Epub 2018-08-23.

PubMed abstract

Accurate Identification of Colonoscopy Quality and Polyp Findings Using Natural Language Processing

Authors: Lee JK; Jensen CD; Levin TR; Zauber AG; Doubeni CA; Zhao WK; Corley DA

J Clin Gastroenterol. 2019 01;53(1):e25-e30.

PubMed abstract

In Screening for Colorectal Cancer, Is the FIT Right for the Right Side of the Colon?

Authors: Doubeni CA; Levin TR

Ann Intern Med. 2018 11 06;169(9):650-651. Epub 2018-10-02.

PubMed abstract

Influence of Varying Quantitative Fecal Immunochemical Test Positivity Thresholds on Colorectal Cancer Detection: A Community-Based Cohort Study

Authors: Selby K; Lee JK; Levin TR; Corley DA; et al.

Ann Intern Med. 2018 10 02;169(7):439-447. Epub 2018-09-18.

PubMed abstract

Effects of Organized Colorectal Cancer Screening on Cancer Incidence and Mortality in a Large, Community-based Population

Authors: Levin TR; Corley DA; Lee JK; Quesenberry CP; Fireman BH; Doubeni CA; et al.

Gastroenterology. 2018 11;155(5):1383-1391.e5. Epub 2018-07-19.

PubMed abstract

Diagnosis of sessile serrated adenoma after educational training in a large, community-based, integrated healthcare setting

Authors: Li D; Corley DA; Levin TR; et al.

Gastrointest Endosc. 2018 Mar;87(3):755-765.e1. Epub 2017-08-24.

PubMed abstract

Effectiveness of screening colonoscopy in reducing the risk of death from right and left colon cancer: a large community-based study

Authors: Doubeni CA; Corley DA; Levin TR; Fletcher RH; et al.

Gut. 2018 02;67(2):291-298. Epub 2016-10-12.

PubMed abstract

A Comparison of Fecal Immunochemical and High-Sensitivity Guaiac Tests for Colorectal Cancer Screening

Authors: Shapiro JA; Bobo JK; Church TR; Rex DK; Chovnick G; Thompson TD; Zauber AG; Lieberman D; Levin TR; Joseph DA; Nadel MR

Am J Gastroenterol. 2017 Nov;112(11):1728-1735. Epub 2017-10-10.

PubMed abstract

Colorectal Cancer Screening: Money Isn’t Everything…But it Helps!

Authors: Levin TR

Gastroenterology. 2017 11;153(5):1181-1183. Epub 2017-10-04.

PubMed abstract

Interventions to Improve Follow-up of Positive Results on Fecal Blood Tests: A Systematic Review

Authors: Selby K; Baumgartner C; Levin TR; Doubeni CA; Zauber AG; Schottinger J; Jensen CD; Lee JK; Corley DA

Ann Intern Med. 2017 Oct 17;167(8):565-575. Epub 2017-10-10.

PubMed abstract

Colorectal Cancer Screening Initiation After Age 50 Years in an Organized Program

Authors: Fedewa SA; Corley DA; Jensen CD; Zhao W; Goodman M; Jemal A; Ward KC; Levin TR; Doubeni CA

Am J Prev Med. 2017 Sep;53(3):335-344. Epub 2017-04-17.

PubMed abstract

Time to Diagnostic Testing After a Positive Colorectal Cancer Screening Test

Authors: Doubeni CA; Corley DA; Levin TR

JAMA. 2017 Aug 01;318(5):483.

PubMed abstract

Colorectal cancer screening: Recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer

Authors: Rex DK; Boland CR; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Levin TR; Lieberman D; Robertson DJ

Gastrointest Endosc. 2017 Jul;86(1):18-33. Epub 2017-06-06.

PubMed abstract

Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer

Authors: Rex DK; Boland CR; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Levin TR; Lieberman D; Robertson DJ

Gastroenterology. 2017 Jul;153(1):307-323. Epub 2017-06-09.

PubMed abstract

Colorectal Cancer Screening: Recommendations for Physicians and Patients from the U.S. Multi-Society Task Force on Colorectal Cancer

Authors: Rex DK; Boland CR; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Levin TR; Lieberman D; Robertson DJ

Am J Gastroenterol. 2017 Jul;112(7):1016-1030. Epub 2017-06-06.

PubMed abstract

Recommendations on surveillance and management of biallelic mismatch repair deficiency (BMMRD) syndrome: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer

Authors: Durno C; Boland CR; Cohen S; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Levin TR; Lieberman D; Robertson DJ; Rex DK

Gastrointest Endosc. 2017 May;85(5):873-882. Epub 2017-03-28.

PubMed abstract

Recommendations on Surveillance and Management of Biallelic Mismatch Repair Deficiency (BMMRD) Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer

Authors: Durno C; Boland CR; Cohen S; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Levin TR; Lieberman D; Robertson DJ; Rex DK

Gastroenterology. 2017 May;152(6):1605-1614. Epub 2017-03-28.

PubMed abstract

Recommendations on Surveillance and Management of Biallelic Mismatch Repair Deficiency Syndrome: A Consensus Statement by the US Multi-society Task Force on Colorectal Cancer

Authors: Durno C; Boland CR; Cohen S; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Levin TR; Lieberman D; Robertson DJ; Rex DK

J Pediatr Gastroenterol Nutr. 2017 05;64(5):836-843.

PubMed abstract

Recommendations on Surveillance and Management of Biallelic Mismatch Repair Deficiency (BMMRD) Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer

Authors: Durno C; Boland CR; Cohen S; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Levin TR; Lieberman D; Robertson DJ; Rex DK

Am J Gastroenterol. 2017 May;112(5):682-690. Epub 2017-03-28.

PubMed abstract

Association Between Time to Colonoscopy After a Positive Fecal Test Result and Risk of Colorectal Cancer and Cancer Stage at Diagnosis

Authors: Corley DA; Lee JK; Quesenberry CP; Fireman BH; Levin TR; et al.

JAMA. 2017 Apr 25;317(16):1631-1641.

PubMed abstract

Recommendations on Fecal Immunochemical Testing to Screen for Colorectal Neoplasia: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer

Authors: Robertson DJ; Lee JK; Boland CR; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Lieberman D; Levin TR; Rex DK

Gastroenterology. 2017 Apr;152(5):1217-1237.e3. Epub 2016-10-19.

PubMed abstract

In simulation modelling, there are multiple ways to effectively screen for colorectal cancer

Authors: Levin TR

Evid Based Med. 2017 04;22(2):59. Epub 2017-01-10.

PubMed abstract

Endoscopist Fatigue Estimates and Colonoscopic Adenoma Detection in a Large Community-Based Setting

Authors: Lee A; Jensen CD; Marks AR; Zhao WK; Doubeni CA; Zauber AG; Quinn VP; Levin TR; Corley DA

Gastrointest Endosc. 2017 Mar;85(3):601-610.e2. Epub 2016-10-01.

PubMed abstract

The Best Laid Plans: Adaptation is an Essential Part of Going From Efficacy Research to Program Implementation

Authors: Levin TR

Gastroenterology. 2017 03;152(4):693-694. Epub 2017-01-29.

PubMed abstract

Genetic Biomarker Prevalence Is Similar in Fecal Immunochemical Test Positive and Negative Colorectal Cancer Tissue

Authors: Levin TR; Corley DA; Berger BM; et al.

Dig Dis Sci. 2017 Mar;62(3):678-688. Epub 2017-01-02.

PubMed abstract

Fecal Immunochemical Test (FIT) for Colon Cancer Screening: Variable Performance with Ambient Temperature

Authors: Doubeni CA; Jensen CD; Fedewa SA; Quinn VP; Zauber AG; Schottinger JE; Corley DA; Levin TR

J Am Board Fam Med. 2016 11/12;29(6):672-681.

PubMed abstract

Shifts in the fecal microbiota associated with adenomatous polyps

Authors: Hale VL; Levin TR; Chia N; et al.

Cancer Epidemiol Biomarkers Prev. 2017 Jan;26(1):85-94. Epub 2016-09-26.

PubMed abstract

Recommendations on fecal immunochemical testing to screen for colorectal neoplasia: a consensus statement by the US Multi-Society Task Force on colorectal cancer

Authors: Robertson DJ; Lee JK; Boland CR; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Lieberman D; Levin TR; Rex DK

Gastrointest Endosc. 2017 Jan;85(1):2-21.e3. Epub 2016-10-18.

PubMed abstract

Recommendations on Fecal Immunochemical Testing to Screen for Colorectal Neoplasia: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer

Authors: Robertson DJ; Lee JK; Boland CR; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Lieberman D; Levin TR; Rex DK

Am J Gastroenterol. 2017 Jan;112(1):37-53. Epub 2016-10-18.

PubMed abstract

Beyond Colonoscopy: The Role of Alternative Screening Tests for Colorectal Cancer in Your Practice

Authors: Levin TR

Am J Gastroenterol. 2017 01;112(1):8-10. Epub 2016-11-01.

PubMed abstract

Race/Ethnicity and Adoption of a Population Health Management Approach to Colorectal Cancer Screening in a Community-Based Healthcare System

Authors: Mehta SJ; Levin TR; Corley DA; Doubeni CA; et al.

J Gen Intern Med. 2016 Nov;31(11):1323-1330. Epub 2016-07-13.

PubMed abstract

Consequences of Increasing Time to Colonoscopy Examination Following Positive Result From Fecal Colorectal Cancer Screening Test

Authors: Meester RG; Zauber AG; Doubeni CA; Jensen CD; Quinn VP; Helfand M; Dominitz JA; Levin TR; Corley DA; Lansdorp-Vogelaar I

Clin Gastroenterol Hepatol. 2016 Oct;14(10):1445-1451.e8. Epub 2016-05-19.

PubMed abstract

Fecal Immunochemical Test Program Performance Over 4 Rounds of Annual Screening: A Retrospective Cohort Study

Authors: Jensen CD; Corley DA; Lee JK; Quesenberry CP; Levin TR; Mysliwiec PA; et al.

Ann Intern Med. 2016 Apr 5;164(7):456-63. Epub 2016-01-26.

PubMed abstract

Colorectal cancer screening: 80% by 2018. Colonoscopists simply cannot do it alone

Authors: Levin TR

Gastrointest Endosc. 2016 Mar;83(3):552-4.

PubMed abstract

Colonoscopy Surveillance After Colorectal Cancer Resection: Recommendations of the US Multi-Society Task Force on Colorectal Cancer

Authors: Kahi CJ; Boland CR; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Lieberman D; Levin TR; Robertson DJ; Rex DK; United States Multi-Society Task Force on Colorectal Cancer

Gastroenterology. 2016 Mar;150(3):758-768.e11. Epub 2016-02-10.

PubMed abstract

Colonoscopy surveillance after colorectal cancer resection: recommendations of the US multi-society task force on colorectal cancer

Authors: Kahi CJ; Boland CR; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Lieberman D; Levin TR; Robertson DJ; Rex DK

Gastrointest Endosc. 2016 Mar;83(3):489-98.e10. Epub 2016-01-21.

PubMed abstract

Colonoscopy Surveillance after Colorectal Cancer Resection: Recommendations of the US Multi-Society Task Force on Colorectal Cancer

Authors: Kahi CJ; Boland CR; Dominitz JA; Giardiello FM; Johnson DA; Kaltenbach T; Lieberman D; Levin TR; Robertson DJ; Rex DK

Am J Gastroenterol. 2016 Mar;111(3):337-46; quiz 347. Epub 2016-02-12.

PubMed abstract

Factors Influencing Variation in Physician Adenoma Detection Rates: a Theory-Based Approach for Performance Improvement

Authors: Atkins L; Hunkeler EM; Jensen CD; Michie S; Lee JK; Doubeni CA; Zauber AG; Levin TR; Quinn VP; Corley DA

Gastrointest Endosc. 2016 Mar;83(3):617-26.e2. Epub 2015-09-11.

PubMed abstract

Time to Colonoscopy after Positive Fecal Blood Test in Four U.S. Health Care Systems

Authors: Chubak J; Corley DA; Levin TR; PROSPR consortium; et al.

Cancer Epidemiol Biomarkers Prev. 2016 Feb;25(2):344-50.

PubMed abstract

Ten-year incidence of colorectal cancer following a negative screening sigmoidoscopy: an update from the Colorectal Cancer Prevention (CoCaP) programme

Authors: Doria-Rose VP; Levin TR; Palitz A; Conell C; Weiss NS

Gut. 2016 Feb;65(2):271-7. Epub 2014-12-15.

PubMed abstract

Public health impact of achieving 80% colorectal cancer screening rates in the United States by 2018

Authors: Meester RG; Doubeni CA; Zauber AG; Goede SL; Levin TR; Corley DA; Jemal A; Lansdorp-Vogelaar I

Cancer. 2015 Jul 1;121(13):2281-5. Epub 2015-03-12.

PubMed abstract

Variation in Adenoma Detection Rate and the Lifetime Benefits and Cost of Colorectal Cancer Screening: A Microsimulation Model

Authors: Meester RG; Doubeni CA; Lansdorp-Vogelaar I; Jensen CD; van der Meulen MP; Levin TR; Quinn VP; Schottinger JE; Zauber AG; Corley DA; van Ballegooijen M

JAMA. 2015 Jun 16;313(23):2349-58.

PubMed abstract

CDC Grand Rounds: the Future of Cancer Screening

Authors: Thomas CC; Richards TB; Plescia M; Wong FL; Ballard R; Levin TR; Calonge BN; Brawley OW; Iskander J; Centers for Disease Control and Prevention (CDC)

MMWR Morb Mortal Wkly Rep. 2015 Apr 3;64(12):324-7.

PubMed abstract

Adjusting for Patient Demographics Has Minimal Effects on Rates of Adenoma Detection in a Large, Community-based Setting

Authors: Jensen CD; Levin TR; Lee JK; Fireman BH; Quesenberry CP; Corley DA; et al.

Clin Gastroenterol Hepatol. 2015 Apr;13(4):739-46. Epub 2014-10-25.

PubMed abstract

Development and validation of an algorithm for classifying colonoscopy indication

Authors: Lee JK; Jensen CD; Lee A; Doubeni CA; Zauber AG; Levin TR; Zhao WK; Corley DA

Gastrointest Endosc. 2015 Mar;81(3):575-582.e4. Epub 2015-01-08.

PubMed abstract

Colorectal cancer deaths attributable to nonuse of screening in the United States

Authors: Meester RG; Doubeni CA; Lansdorp-Vogelaar I; Goede SL; Levin TR; Quinn VP; Ballegooijen Mv; Corley DA; Zauber AG

Ann Epidemiol. 2015 Mar;25(3):208-213.e1. Epub 2014-12-05.

PubMed abstract

Lack of significant association between serum inflammatory cytokine profiles and the presence of colorectal adenoma

Authors: Henry CJ; Sedjo RL; Rozhok A; Salstrom J; Ahnen D; Levin TR; D'Agostino R; Haffner S; DeGregori J; Byers T

BMC Cancer. 2015;15:123. Epub 2015-03-14.

PubMed abstract

Optimizing Adequacy of Bowel Cleansing for Colonoscopy: Recommendations From the US Multi-Society Task Force on Colorectal Cancer

Authors: Johnson DA; Levin TR; US Multi-Society Task Force on Colorectal Cancer; et al.

Am J Gastroenterol. 2014 Oct;109(10):1528-45. Epub 2014-09-16.

PubMed abstract

Optimizing Adequacy of Bowel Cleansing for Colonoscopy: Recommendations From the US Multi-Society Task Force on Colorectal Cancer

Authors: Johnson DA; Levin TR; US Multi-Society Task Force on Colorectal Cancer; et al.

Gastroenterology. 2014 Oct;147(4):903-24.

PubMed abstract

Optimizing adequacy of bowel cleansing for colonoscopy: recommendations from the U.S. Multi-Society Task Force on Colorectal Cancer

Authors: Johnson DA; Levin TR; Rex DK; et al.

Gastrointest Endosc. 2014 Oct;80(4):543-62.

PubMed abstract

Guidelines on genetic evaluation and management of Lynch syndrome: A consensus statement by the U.S. Multi-Society Task Force on Colorectal Cancer

Authors: Giardiello FM; Levin TR; American Society for Gastrointestinal Endoscopy; et al.

Gastrointest Endosc. 2014 Aug;80(2):197-220.

PubMed abstract

Guidelines on Genetic Evaluation and Management of Lynch Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer

Authors: Giardiello FM; Levin TR; Rex DK; et al.

Am J Gastroenterol. 2014 Aug;109(8):1159-79. Epub 2014-07-22.

PubMed abstract

Guidelines on Genetic Evaluation and Management of Lynch Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer

Authors: Giardiello FM; Levin TR; Rex DK; et al.

Dis Colon Rectum. 2014 Aug;57(8):1025-48.

PubMed abstract

Guidelines on Genetic Evaluation and Management of Lynch Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer

Authors: Giardiello FM; Levin TR; US Multi-Society Task Force on Colorectal Cancer; et al.

Gastroenterology. 2014 Aug;147(2):502-26.

PubMed abstract

The Colorectal Cancer Screening Process in Community Settings: A Conceptual Model for the Population-Based Research Optimizing Screening through Personalized Regimens Consortium

Authors: Tiro JA; Levin TR; Corley DA; Klabunde C; et al.

Cancer Epidemiol Biomarkers Prev. 2014 Jul;23(7):1147-58. Epub 2014-06-10.

PubMed abstract

Adenoma detection rate and risk of colorectal cancer and death

Authors: Corley DA; Lee JK; Fireman BH; Levin TR; Quesenberry CP; et al.

N Engl J Med. 2014 Apr 3;370(14):1298-306.

PubMed abstract

Multitarget Stool DNA Testing for Colorectal-Cancer Screening

Authors: Imperiale TF; Ransohoff DF; Itzkowitz SH; Levin TR; Lavin P; Lidgard GP; Ahlquist DA; Berger BM

N Engl J Med. 2014 Apr 3;370(14):1287-97. Epub 2014-03-19.

PubMed abstract

Accuracy of fecal immunochemical tests for colorectal cancer: systematic review and meta-analysis

Authors: Lee JK; Liles EG; Bent S; Levin TR; Corley DA

Ann Intern Med. 2014 Feb 4;160(3):171.

PubMed abstract

Health Benefits and Cost-Effectiveness of a Hybrid Screening Strategy for Colorectal Cancer

Authors: Dinh T; Ladabaum U; Alperin P; Caldwell C; Smith R; Levin TR

Clin Gastroenterol Hepatol. 2013 Sep;11(9):1158-66. Epub 2013-03-28.

PubMed abstract

Effectiveness and Reach of the FLU-FIT Program in an Integrated Health Care System: A Multisite Randomized Trial

Authors: Potter MB; Ackerson LM; Gomez V; Walsh JM; Green LW; Levin TR; Somkin CP

Am J Public Health. 2013 Jun;103(6):1128-33. Epub 2013 Apr 18.

PubMed abstract

Screening colonoscopy and risk for incident late-stage colorectal cancer diagnosis in average-risk adults: a nested case-control study

Authors: Doubeni CA; Corley DA; Levin TR; Weiss NS; et al.

Ann Intern Med. 2013 Mar 5;158(5 Pt 1):312-20.

PubMed abstract

Sexual transmission of HCV among monogamous heterosexual couples: The HCV partners study

Authors: Terrault NA; Dodge JL; Murphy EL; Tavis JE; Kiss A; Levin TR; Gish RG; Busch MP; Reingold AL; Alter MJ

Hepatology. 2013 Mar;57(3):881-9. Epub 2013 Feb 7.

PubMed abstract

The Road Ahead: What if Gastroenterologists Were Accountable for Preventing Colorectal Cancer?

Authors: Lee JK; Levin TR; Corley DA

Clin Gastroenterol Hepatol. 2013 Mar;11(3):204-7.

PubMed abstract

Variation of Adenoma Prevalence by Age, Sex, Race, and Colon Location in a Large Population: Implications for Screening and Quality Programs

Authors: Corley DA; Jensen CD; Marks AR; Zhao WK; de Boer J; Levin TR; Doubeni C; Fireman BH; Quesenberry CP

Clin Gastroenterol Hepatol. 2013 Feb;11(2):172-80. Epub 2012 Sep 14.

PubMed abstract

Guidelines for Colonoscopy Surveillance After Screening and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer

Authors: Lieberman DA; Rex DK; Winawer SJ; Giardiello FM; Johnson DA; Levin TR

Gastroenterology. 2012 Sep;143(3):844-57. Epub 2012 Jul 3.

PubMed abstract

Incidence and Mortality of Colorectal Adenocarcinoma in Persons with Inflammatory Bowel Disease from 1998 to 2010

Authors: Herrinton LJ; Liu L; Levin TR; Allison JE; Lewis JD; Velayos F

Gastroenterology. 2012 Aug;143(2):382-9. Epub 2012 May 15.

PubMed abstract

Automated phone and mail population outreach to promote colorectal cancer screening

Authors: Kempe KL; Shetterly SM; France EK; Levin TR

Am J Manag Care. 2012 Jul;18(7):370-8.

PubMed abstract

The importance of choosing colorectal cancer screening tests: comment on ‘adherence to colorectal cancer screening’

Authors: Levin TR

Arch Intern Med. 2012 Apr 9;172(7):582-3.

PubMed abstract

Diagnosis, Comorbidities, and Management of Irritable Bowel Syndrome in Patients in a Large Health Maintenance Organization

Authors: Ladabaum U; Boyd E; Zhao WK; Mannalithara A; Sharabidze A; Singh G; Chung E; Levin TR

Clin Gastroenterol Hepatol. 2012 Jan;10(1):37-45. Epub 2011 Aug 24.

PubMed abstract

Editorial: Taking FIT to the People: Out of the Office and Into the Mail

Authors: Levin TR

Am J Gastroenterol. 2012 Jan;107(1):108-10.

PubMed abstract

Optimizing Colorectal Cancer Screening by Getting FIT Right

Authors: Levin TR

Gastroenterology. 2011 Nov;141(5):1551-5. Epub 2011 Sep 22.

PubMed abstract

The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on real-time endoscopic assessment of the histology of diminutive colorectal polyps

Authors: Rex DK; Kahi C; O'Brien M; Levin TR; Pohl H; Rastogi A; Burgart L; Imperiale T; Ladabaum U; Cohen J; Lieberman DA

Gastrointest Endosc. 2011 Mar;73(3):419-22.

PubMed abstract

Organized colorectal cancer screening in integrated health care systems

Authors: Levin TR; Jamieson L; Burley DA; Reyes J; Oehrli M; Caldwell C

Epidemiol Rev. 2011;33(1):101-10. Epub 2011 Jun 27.

PubMed abstract

Lack of association between insulin sensitivity and colorectal adenoma risk

Authors: Sedjo RL; D'Agostino RB; Ahnen D; Levin TR; Haffner SM; Tooze JA; Byers T

Nutr Cancer. 2011 Jan;63(1):6-11.

PubMed abstract

Serial glycosylated hemoglobin levels and risk of colorectal neoplasia among patients with type 2 diabetes mellitus

Authors: Yang YX; Habel LA; Capra AM; Achacoso NS; Ferrara A; Levin TR; Lewis JD; Quesenberry CP Jr

Cancer Epidemiol Biomarkers Prev. 2010 Dec;19(12):3027-36. Epub 2010 Oct 11.

PubMed abstract

Citalopram provides little or no benefit in nondepressed patients with irritable bowel syndrome

Authors: Ladabaum U; Sharabidze A; Levin TR; Zhao WK; Chung E; Bacchetti P; Jin C; Grimes B; Pepin CJ

Clin Gastroenterol Hepatol. 2010 Jan;8(1):42-48.e1. Epub 2009 Sep 16.

PubMed abstract

Editorial: It’s time to make organized colorectal cancer screening convenient and easy for patients

Authors: Levin TR

Am J Gastroenterol. 2009 Apr;104(4):939-41. Epub 2009 Mar 17.

PubMed abstract

Cigarette smoking and the risk of Barrett’s esophagus

Authors: Kubo A; Levin TR; Block G; Rumore G; Quesenberry CP Jr; Buffler P; Corley DA

Cancer Causes Control. 2009 Apr;20(3):303-11. Epub 2008 Oct 14.

PubMed abstract

Alcohol types and sociodemographic characteristics as risk factors for Barrett’s esophagus

Authors: Kubo A; Levin TR; Block G; Rumore GJ; Quesenberry CP Jr; Buffler P; Corley DA

Gastroenterology. 2009 Mar;136(3):806-15. Epub 2008 Nov 27.

PubMed abstract

Race, ethnicity, sex and temporal differences in Barrett’s oesophagus diagnosis: a large community-based study, 1994-2006

Authors: Corley DA; Kubo A; Levin TR; Block G; Habel L; Rumore G; Quesenberry C; Buffler P

Gut. 2009 Feb;58(2):182-8. Epub 2008 Oct 31.

PubMed abstract

Hemochromatosis gene status as a risk factor for Barrett’s esophagus

Authors: Corley DA; Kubo A; Levin TR; Block G; Habel L; Rumore GJ; Quesenberry C; Buffler P

Dig Dis Sci. 2008 Dec;53(12):3095-102. Epub 2008 May 10.

PubMed abstract

Iron intake and body iron stores as risk factors for Barrett’s esophagus: a community-based study

Authors: Corley DA; Kubo A; Levin TR; Habel L; Zhao W; Leighton P; Rumore G; Quesenberry C; Buffler P; Block G

Am J Gastroenterol. 2008 Dec;103(12):2997-3004. Epub 2008 Oct 1.

PubMed abstract

Thiazolidinedione therapy is not associated with increased colonic neoplasia risk in patients with diabetes mellitus

Authors: Lewis JD; Capra AM; Achacoso NS; Ferrara A; Levin TR; Quesenberry CP Jr; Habel LA

Gastroenterology. 2008 Dec;135(6):1914-23, 1923.e1. Epub 2008 Sep 13.

PubMed abstract

Stool DNA and occult blood testing for screen detection of colorectal neoplasia

Authors: Ahlquist DA; Levin TR; Allison JE; Hillman SL; et al.

Ann Intern Med. 2008 Oct 7;149(7):441-50, W81.

PubMed abstract

Helicobacter pylori and gastroesophageal reflux disease: a case-control study

Authors: Corley DA; Kubo A; Levin TR; Block G; Habel L; Rumore G; Quesenberry C; Buffler P; Parsonnet J

Helicobacter. 2008 Oct;13(5):352-60.

PubMed abstract

Dietary antioxidants, fruits, and vegetables and the risk of Barrett’s esophagus

Authors: Kubo A; Levin TR; Block G; Rumore GJ; Quesenberry CP Jr; Buffler P; Corley DA

Am J Gastroenterol. 2008 Jul;103(7):1614-23; quiz 1624.

PubMed abstract

Helicobacter pylori infection and the risk of Barrett’s oesophagus: a community-based study

Authors: Corley DA; Kubo A; Levin TR; Block G; Habel L; Zhao W; Leighton P; Rumore G; Quesenberry C; Buffler P; Parsonnet J

Gut. 2008 Jun;57(6):727-33. Epub 2007 Sep 25.

PubMed abstract

Dietary patterns and the risk of Barrett’s esophagus

Authors: Kubo A; Levin TR; Block G; Rumore GJ; Quesenberry CP Jr; Buffler P; Corley DA

Am J Epidemiol. 2008 Apr 1;167(7):839-46. Epub 2008 Jan 23.

PubMed abstract

Hepatic effects of lovastatin exposure in patients with liver disease: a retrospective cohort study

Authors: Avins AL; Manos MM; Ackerson L; Zhao W; Murphy R; Levin TR; Watson DJ; Hwang PM; Replogle A; Levine JG

Drug Saf. 2008;31(4):325-34.

PubMed abstract

Medical therapy for diabetes is associated with increased use of lower endoscopy

Authors: Lewis JD; Capra AM; Achacoso NS; Ferrara A; Levin TR; Quesenberry CP Jr; Habel LA

Pharmacoepidemiol Drug Saf. 2007 Nov;16(11):1195-202.

PubMed abstract

Screening for colorectal neoplasms with new fecal occult blood tests: update on performance characteristics

Authors: Allison JE; Levin TR; Selby JV; et al.

J Natl Cancer Inst. 2007 Oct 3;99(19):1462-70. Epub 2007 Sep 25.

PubMed abstract

Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet

Authors: Curtin K; Slattery ML; Ulrich CM; Bigler J; Levin TR; Wolff RK; Albertsen H; Potter JD; Samowitz WS

Carcinogenesis. 2007 Aug;28(8):1672-9. Epub 2007 Apr 21.

PubMed abstract

Dealing with uncertainty: surveillance colonoscopy after polypectomy

Authors: Levin TR

Am J Gastroenterol. 2007 Aug;102(8):1745-7.

PubMed abstract

Abdominal obesity and body mass index as risk factors for Barrett’s esophagus

Authors: Corley DA; Kubo A; Levin TR; Block G; Habel L; Zhao W; Leighton P; Quesenberry C; Rumore GJ; Buffler PA

Gastroenterology. 2007 Jul;133(1):34-41; quiz 311. Epub 2007 Apr 25.

PubMed abstract

Standardized colonoscopy reporting and data system: report of the Quality Assurance Task Group of the National Colorectal Cancer Roundtable

Authors: Lieberman D; Levin TR; Winawer S; et al.

Gastrointest Endosc. 2007 May;65(6):757-66.

PubMed abstract

Change in body size and the risk of colorectal adenomas

Authors: Sedjo RL; Byers T; Levin TR; Haffner SM; Saad MF; Tooze JA; D'Agostino RB Jr

Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):526-31.

PubMed abstract

Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer

Authors: Slattery ML; Curtin K; Sweeney C; Levin TR; Potter J; Wolff RK; Albertsen H; Samowitz WS

Int J Cancer. 2007 Feb 1;120(3):656-63.

PubMed abstract

Complications of colonoscopy in an integrated health care delivery system

Authors: Levin TR; Zhao W; Conell C; Seeff LC; Manninen DL; Shapiro JA; Schulman J

Ann Intern Med. 2006 Dec 19;145(12):880-6.

PubMed abstract

Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention

Authors: Samowitz WS; Wolff RK; Curtin K; Sweeney C; Ma KN; Andersen K; Levin TR; Slattery ML

Clin Gastroenterol Hepatol. 2006 Jul;4(7):894-901. Epub 2006 Jun 22.

PubMed abstract

Guidelines for colonoscopy surveillance after cancer resection: a consensus update by the American Cancer Society and the US Multi-Society Task Force on Colorectal Cancer

Authors: Rex DK; Levin TR; US Multi-Society Task Force on Colorectal Cancer; et al.

Gastroenterology. 2006 May;130(6):1865-71.

PubMed abstract

Barrett’s esophagus and medications that relax the lower esophageal sphincter

Authors: Corley DA; Levin TR; Habel LA; Buffler PA

Am J Gastroenterol. 2006 May;101(5):937-44.

PubMed abstract

Guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society

Authors: Winawer SJ; Levin TR; Rex DK; et al.

CA Cancer J Clin. 2006 May-Jun;56(3):143-59; quiz 184-5.

PubMed abstract

PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States)

Authors: Slattery ML; Curtin K; Wolff R; Ma KN; Sweeney C; Murtaugh M; Potter JD; Levin TR; Samowitz W

Cancer Causes Control. 2006 Apr;17(3):239-49.

PubMed abstract

Reducing unnecessary surveillance colonoscopies: a mandate for endoscopists

Authors: Levin TR

Gastrointest Endosc. 2006 Jan;63(1):104-6.

PubMed abstract

Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer

Authors: Samowitz WS; Albertsen H; Herrick J; Levin TR; Sweeney C; Murtaugh MA; Wolff RK; Slattery ML

Gastroenterology. 2005 Sep;129(3):837-45.

PubMed abstract

Incomplete screening flexible sigmoidoscopy associated with female sex, age, and increased risk of colorectal cancer

Authors: Doria-Rose VP; Newcomb PA; Levin TR

Gut. 2005 Sep;54(9):1273-8. Epub 2005 May 4.

PubMed abstract

Associations between apoE genotype and colon and rectal cancer

Authors: Slattery ML; Sweeney C; Murtaugh M; Ma KN; Potter JD; Levin TR; Samowitz W; Wolff R

Carcinogenesis. 2005 Aug;26(8):1422-9. Epub 2005 Apr 7.

PubMed abstract

Quality in the technical performance of screening flexible sigmoidoscopy: recommendations of an international multi-society task group

Authors: Levin TR; Rex DK; et al.

Gut. 2005 Jun;54(6):807-13.

PubMed abstract

Colonoscopy capacity: Can we build it? Will they come?

Authors: Levin TR

Gastroenterology. 2004 Dec;127(6):1841-4.

PubMed abstract

The incidence of colorectal cancer following a negative screening sigmoidoscopy: implications for screening interval

Authors: Doria-Rose VP; Levin TR; Selby JV; Newcomb PA; Richert-Boe KE; Weiss NS

Gastroenterology. 2004 Sep;127(3):714-22.

PubMed abstract

The evolution to stool DNA testing for colorectal cancer

Authors: Tagore KS; Levin TR; Lawson MJ

Aliment Pharmacol Ther. 2004 Jun 15;19(12):1225-33.

PubMed abstract

Screening in liver disease: report of an AASLD clinical workshop

Authors: Adams PC; Arthur MJ; Boyer TD; DeLeve LD; Di Bisceglie AM; Hall M; Levin TR; Provenzale D; Seeff L

Hepatology. 2004 May;39(5):1204-12.

PubMed abstract

Factors associated with colorectal cancer screening in a population-based study: the impact of gender, health care source, and time

Authors: Slattery ML; Kinney AY; Levin TR

Prev Med. 2004 Mar;38(3):276-83.

PubMed abstract

Family history and colorectal cancer: predictors of risk

Authors: Slattery ML; Levin TR; Ma K; Goldgar D; Holubkov R; Edwards S

Cancer Causes Control. 2003 Nov;14(9):879-87.

PubMed abstract

What does sigmoidoscopy really miss?

Authors: Levin TR

Am J Gastroenterol. 2003 Oct;98(10):2326-7.

PubMed abstract

A randomized controlled trial of test-and-treat strategy for Helicobacter pylori: clinical outcomes and health care costs in a managed care population receiving long-term acid suppression therapy for physician-diagnosed peptic ulcer disease

Authors: Allison JE; Hurley LB; Hiatt RA; Levin TR; Ackerson LM; Lieu TA

Arch Intern Med. 2003 May 26;163(10):1165-71.

PubMed abstract

Does family history still matter in the era of screening colonoscopy?

Authors: Levin TR

Clin Gastroenterol Hepatol. 2003 Mar;1(2):69-70.

PubMed abstract

Colorectal cancer screening and surveillance: clinical guidelines and rationale-Update based on new evidence

Authors: Winawer S; Levin T; Gastrointestinal Consortium Panel; et al.

Gastroenterology. 2003 Feb;124(2):544-60.

PubMed abstract

Flexible sigmoidoscopy for colorectal cancer screening: valid approach or short-sighted?

Authors: Levin TR

Gastroenterol Clin North Am. 2002 Dec;31(4):1015-29, vii.

PubMed abstract

Complications of screening flexible sigmoidoscopy

Authors: Levin TR; Conell C; Shapiro JA; Chazan SG; Nadel MR; Selby JV

Gastroenterology. 2002 Dec;123(6):1786-92.

PubMed abstract

Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on Colorectal Cancer

Authors: Rex DK; Levin TR; U.S.Multi-Society Task Force on Colorectal Cancer; et al.

Am J Gastroenterol. 2002 Jun;97(6):1296-308.

PubMed abstract

Gastric and duodenal safety of daily alendronate

Authors: Donahue JG; Levin TR; Platt R; et al.

Arch Intern Med. 2002 Apr 22;162(8):936-42.

PubMed abstract

Hereditary nonpolyposis colorectal cancer in young colorectal cancer patients: high-risk clinic versus population-based registry

Authors: Terdiman JP; Levin TR; Allen BA; Gum JR Jr; Fishbach A; Conrad PG; Miller GA; Weinberg V; Bachman R; Bergoffen J; Stembridge A; Toribara NW; Sleisenger MH; Kim YS

Gastroenterology. 2002 Apr;122(4):940-7.

PubMed abstract

Surveillance and survival in Barrett’s adenocarcinomas: a population-based study

Authors: Corley DA; Levin TR; Habel LA; Weiss NS; Buffler PA

Gastroenterology. 2002 Mar;122(3):633-40.

PubMed abstract

Validation of diagnoses of peptic ulcers and bleeding from administrative databases: a multi-health maintenance organization study

Authors: Andrade SE; Gurwitz JH; Chan KA; Donahue JG; Beck A; Boles M; Buist DS; Goodman M; LaCroix AZ; Levin TR; Platt R

J Clin Epidemiol. 2002 Mar;55(3):310-3.

PubMed abstract

Flexible sigmoidoscopy: an important screening option for average-risk individuals

Authors: Levin TR; Palitz AM

Gastrointest Endosc Clin N Am. 2002 Jan;12(1):23-40, vi.

PubMed abstract

Quality of life measurement clarifies the cost-effectiveness of Helicobacter pylori eradication in peptic ulcer disease and uninvestigated dyspepsia

Authors: Groeneveld PW; Lieu TA; Fendrick AM; Hurley LB; Ackerson LM; Levin TR; Allison JE

Am J Gastroenterol. 2001 Feb;96(2):338-47.

PubMed abstract

Cimetidine use and risk of breast, prostate, and other cancers

Authors: Habel LA; Levin TR; Friedman GD

Pharmacoepidemiol Drug Saf. 2000 Mar;9(2):149-55.

PubMed abstract

Work loss costs due to peptic ulcer disease and gastroesophageal reflux disease in a health maintenance organization

Authors: Henke CJ; Levin TR; Henning JM; Potter LP

Am J Gastroenterol. 2000 Mar;95(3):788-92.

PubMed abstract

Colorectal cancer screening: new opportunities

Authors: Levin TR

Surg Oncol Clin N Am. 1999 Oct;8(4):673-91, vi-vii.

PubMed abstract

Predicting advanced proximal colonic neoplasia with screening sigmoidoscopy

Authors: Levin TR; Palitz A; Grossman S; Conell C; Finkler L; Ackerson L; Rumore G; Selby JV

JAMA. 1999 May 5;281(17):1611-7.

PubMed abstract

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July 7, 2023

Investigators from the Division of Research and physicians from The Permanente Medical Group presented research on topics ranging from care delivery to cancer survivorship at the 2023 American Society of Clinical Oncology conference.
5 Questions for . . . Theodore R. “T. R.” Levin

5 Questions for . . . Theodore R. “T. R.” Levin

August 11, 2022

Kaiser Permanente research scientist and TPMG physician leads award-winning colorectal cancer screening program.
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