De-Kun Li, MD, PhD

de-kun.li@kp.org

Kaiser Permanente Researcher Profiles

Li, De-Kun

De-Kun Li, MD, PhD, MPH, is a Senior Research Scientist at the Division of Research, Kaiser Permanente Northern California. Dr. Li completed his medical training and master’s degree in Public Health at Shanghai Medical University, Shanghai, China. He then received his PhD in epidemiology from the University of Washington, Seattle.

Dr. Li is a reproductive and perinatal epidemiologist with extensive experience conducting epidemiologic studies examining in-utero exposures in relation to pregnancy outcomes and early childhood diseases, including childhood obesity and asthma, preterm delivery, low birthweight, birth defects, miscarriage and SIDS. He has more than 88 peer-reviewed publications, of which he first-authored 41 and was the senior author for another 18.

He has been invited to many NIH and CDC study sections to review grant applications. Recognized for his long-standing experience in international collaborative research, Dr. Li was invited by the US National Academy of Science to evaluate Sino-US collaboration in bio-medical research. He has been invited by academic institutions and governmental agencies to present his research findings, including those related to exposures to EDC pollutants, genetic contribution, and medication use during pregnancy in relation to pregnancy outcomes and childhood diseases. He is also a current member of an advisory committee for the Dartmouth Children’s Environmental Health and Disease Prevention Research Center.

He has received more than 10 research grants from federal agencies including NIH, CDC, FDA, and AHRQ. He is currently serving as the Associate Editor of the American Journal of Epidemiology.

Dr. Li’s current research focuses on developmental origins of pregnancy outcomes and childhood diseases which include examination of (1) in-utero environmental exposures including endocrine disruptors (e.g., BPA) and electromagnetic fields (EMF), (2) safety and effectiveness of medication use during pregnancy, and (3) gene-environment interactions. Throughout his professional life, he has made important contributions to the understanding of (a) factors associated with reduction in SIDS risk, (b) health effects due to exposure to EMF, (c) adverse effects of in-utero exposure to caffeine, (d) impact of exposure to environmental endocrine disruptors, (e) risk and benefit of treating maternal depression during pregnancy, (f) parental genetic contribution to the risk of preterm delivery, and (g) benefits of treating herpes infection during pregnancy.

Dr. Li has worked closely with the medical communities, especially OBGYN physicians, of Kaiser Permanente Northern California.

Current Positions

  • Research Scientist III, Division of Research, Kaiser Permanente Northern California

Section Affiliations

Primary Research Interests

  • Developmental origins of adverse pregnancy outcomes and childhood diseases.
  • Risk factors for childhood obesity and asthma, especially in-utero and early childhood exposures including environmental risk factors (e.g., endocrine disruptors and EMF), antibiotics, medical conditions, and lifestyle factors (e.g., caffeine intake).
  • Factors impacting the risk of preterm delivery, including maternal depression, infection, and genetics.
  • Etiology of infertility, miscarriage, preterm delivery, preeclampsia, SIDS, cerebral palsy, birth defects; pediatric diseases, including cancer and neurological disorders; autoimmune diseases in relation to maternal-fetal interaction, and breast cancer.
  • Pharmacological effects of medication use during pregnancy on pregnancy outcomes.
  • Genetic and epigenetic determinants of pregnancy outcomes and childhood health.
  • Risk factors for poor semen quality.

Studies

Developing Data Collection Methods to Understand Race-Related Factors Influencing Genital Herpes Infection Reporting and Acceptance of Prescribed Treatments: Uncovering Other Factors Impacting Treatment Effectiveness to Reduce Racial Disparities

Data Collection Methods to Understand Race-Related Factors Influencing Genital Herpes Infection Reporting and Acceptance of Prescribed Treatments
The study seeks to develop data collection methods to determine whether potential race-related factors impacting reporting of genital herpes infection, and acceptance of its treatment exist among African American women.
Funder: KPNC Community Health

Investigator: Li, De-Kun

Funder: Northern California Community Benefit Programs

Risk of Pediatric and Adolescent Cancer Associated with Medical Imaging — Extension Study

This study is an extension of the Risk of Pediatric and Adolescent Cancer Associated with Medical Imaging (RIC). Our aims are to evaluate patterns of medical imaging and associated radiation exposure in children and adults and to determine the risk of pediatric cancers associated with pediatric exposure to medical imaging, focusing on leukemia and including children born in the health system.

Investigator: Li, De-Kun; Kwan, Marilyn

Funder: University of California, San Francisco (UCSF)

Examining the Factors for the Rapid Rise of Colorectal Cancer in Young Adults: Does Increased Medical Use of Radiation and Imaging Technology Contribute to the Rise?

This study is examining whether the secular increase in use of medical radiation therapy and diagnostic imaging technology is associated with the corresponding secular increase in the risk of colorectal cancer among young adults age 50 and under.

Investigator: Li, De-Kun

Funder: Northern California Community Benefit Programs

Comparative Effectiveness of Treating Genital Herpes Infection to Reduce Racial Disparities in the Risk of Severe Maternal Morbidity (SMM)

The goals of the study are to determine whether treating GHSV infection in pregnancy, especially earlier in pregnancy, is effective in mitigating the racial disparities in SMM, and GHSV infection, if untreated, contribute to racial disparities in the risk of SMM

Investigator: Li, De-Kun

Funder: Patient-Centered Outcomes Research Institute

The Epidemiology of SARS-CoV-2 in Pregnancy and Infancy (ESPI) Network: ESPI-Electronic Cohort

Multisite study to describe the incidence, clinical presentation, treatment, clinical course, and outcomes of COVID-19 among pregnant women and up to six months postpartum, and estimate the incidence of COVID-19 hospitalizations and medically attended ambulatory care visits (including telehealth) during pregnancy and for infants up to six months of age.

Investigator: Li, De-Kun

Funder: Centers for Disease Control and Prevention

Extremely Premature Births Cohort Study

The goal of this study is to understand the incidence of extremely preterm birth and associated adverse health conditions and growth abnormality.

Investigator: Li, De-Kun

Funder: Shire plc

Risk of NTD among Live Births Exposed to Maternal Rx Opioids during Early Pregnancy

The objectives of this study are: 1) To measure the association between in utero exposure to prescription opioids during early pregnancy and primary neurulation defects. 2) To evaluate whether the risk of primary neurulation defects (i.e., craniorachischisis, anencephalus, and myelomeningocele) differs among live births exposed compared to live births unexposed to maternal prescription opioids from 18 to 56 days after last menstrual period.

Investigator: Li, De-Kun

Funder: U.S. Food and Drug Administration

Prenatal, Intrapartum and Infant Antibiotic Use and Atopic Diseases in Childhood

This study has the following aims: 1) Assess prenatal, intrapartum and infant antibiotic exposure in relation to atopic dermatitis, allergic rhinitis and asthma. 2) Assess bias due to reverse causality, confounding by early life respiratory infections, and confounding by unmeasured or poorly measured maternal and child factors such as healthcare-seeking behaviors.

Investigator: Li, De-Kun

Funder: National Institute of Allergy and Infectious Diseases

Comparing Effectiveness of Treating Depression With and Without Comorbidity to Improve Fetal Health

The study is to determine (1) whether treating depression during pregnancy will reduce the risk of adverse pregnancy and pediatric outcomes; (2) which treatment is more effective in reducing these risks.

Investigator: Li, De-Kun

Funder: Patient-Centered Outcomes Research Institute

Effectiveness of Treating Prenatal Depression to Reduce Postpartum Depression

This is a population-based two-stage cohort study that will take advantage of a new KPNC region-wide program of peripartum screening for depression which annually screens about 33,000 pregnant women for depression twice during pregnancy and once post-partum. The study will specifically determine: 1) What is the risk of preterm delivery and postpartume depression (PPD) among women who screen positive for depression during pregnancy compared to those who screen negative for depression. 2. What is the effect of three treatment regimens for depression (i.e., group and individual therapies, and pharmacological treatment) on reducing the risk of preterm delivery and PPD. 3) Which treatment is most effective in reducing the risk of preterm delivery and PPD. 4) Is the effectiveness of the treatment related to timing, dose, and duration of the treatment.

Investigator: Li, De-Kun

Funder: Agency for Healthcare Research and Quality

Prenatal Depression: Registry, Treatment Effectiveness to Reduce Preterm Delivery

The goal of this study is to develop a perinatal depression registry to assess the relationship between prenatal depression and preterm delivery, and whether these relationships differ by race or ethnicity. Additionally, we will evaluate whether treatment for prenatal depression reduces the risk of preterm delivery and whether the effectiveness of treatment varies by race or ethnicity.

Investigator: Li, De-Kun

Funder: Health Resources and Services Administration

Publications

Comparative effectiveness of treating prenatal depression with counseling versus antidepressants in relation to preterm delivery

Authors: Li, De-Kun;Ferber, Jeannette R;Odouli, Roxana;Quesenberry, Charles;Avalos, Lyndsay

Am J Obstet Gynecol. 2024 Aug 31.

PubMed abstract

Antimicrobial exposure during infancy in a longitudinal California cohort

Authors: Barca, Hannah C;Ferber, Jeannette;Richards, Megan;Strickland, Matthew;Fernandez, Alfred J;Li, De-Kun;Darrow, Lyndsey A

Pediatr Res. 2024 Apr 03.

PubMed abstract

Maternal obesity and childhood asthma risk: Exploring mediating pathways

Authors: Rosenquist, Natalie A;Richards, Megan;Ferber, Jeannette R;Strickland, Matthew J;Ryu, So Young;Burkin, Heather;Weber, Ann M;Li, De-Kun;Darrow, Lyndsey A

Paediatr Perinat Epidemiol. 2023 Dec 06.

PubMed abstract

Prepregnancy Body Mass Index and Risk of Childhood Asthma

Authors: Rosenquist, Natalie A; Richards, Megan; Ferber, Jeannette R; Li, De-Kun; Ryu, So Young; Burkin, Heather; Strickland, Matthew J; Darrow, Lyndsey A

Allergy. 2023 May;78(5):1234-1244. Epub 2022-12-11.

PubMed abstract

Incidence Rates of Medically Attended COVID-19 in Infants Less Than 6 Months of Age

Authors: Griffin, Isabel; Li, De-Kun; Munoz, Flor M; et al.

Pediatr Infect Dis J. 2023 Apr 01;42(4):315-320. Epub 2023-01-05.

PubMed abstract

Racial-Ethnic Differences in Treatment Initiation for New Diagnoses of Perinatal Depression

Authors: Avalos, Lyndsay A; Nance, Nerissa; Iturralde, Esti; Badon, Sylvia E; Quesenberry, Charles P; Sterling, Stacy; Li, De-Kun; Flanagan, Tracy

Psychiatr Serv. 2023 Apr 01;74(4):341-348. Epub 2022-10-13.

PubMed abstract

Associations between antidepressant use patterns during pregnancy and birth outcomes among periconception antidepressant users

Authors: Nance, Nerissa; Badon, Sylvia E; Ridout, Kathryn; Ahern, Jennifer; Li, De-Kun; Quesenberry, Charles; Avalos, Lyndsay A

Pharmacotherapy. 2023 Mar 05.

PubMed abstract

SARS-CoV-2 testing and detection during peripartum hospitalizations among a multi-center cohort of pregnant persons, March 2020-February 2021

Authors: Delahoy, Miranda J; Li, De Kun; Greenberg, Mara; Naleway, Allison L; et al.

Clin Infect Dis. 2023 Feb 08;76(3):e51-e59.

PubMed abstract

The clinical burden of extremely preterm birth in a large medical records database in the United States: complications, medication use, and healthcare resource utilization

Authors: Siffel, Csaba; Hirst, Andrew K; Sarda, Sujata P; Chen, Hong; Ferber, Jeannette; Kuzniewicz, Michael W; Li, De-Kun

J Matern Fetal Neonatal Med. 2022 Dec;35(26):10271-10278. Epub 2022-09-28.

PubMed abstract

Association of serum folate levels during pregnancy and prenatal depression

Authors: Avalos, Lyndsay A; Nance, Nerissa; Caan, Bette; Sujan, Ayesha C; Uriu-Adams, Janet Y; Li, De-Kun; Quesenberry, Charles P; Hedderson, Monique M

J Matern Fetal Neonatal Med. 2023 Dec;36(1):1-4. Epub 2022-11-17.

PubMed abstract

Medically Attended Influenza During Pregnancy in the 2019-2020 and 2020-2021 Influenza Seasons

Authors: Irving, Stephanie A; Li, De-Kun; Naleway, Allison L; et al.

Obstet Gynecol. 2022 11 01;140(5):874-877. Epub 2022-10-05.

PubMed abstract

The clinical burden of extremely preterm birth in a large medical records database in the United States: Mortality and survival associated with selected complications

Authors: Siffel, Csaba; Hirst, Andrew K; Sarda, Sujata P; Kuzniewicz, Michael W; Li, De-Kun

Early Hum Dev. 2022 08;171:105613. Epub 2022-06-22.

PubMed abstract

Intrapartum antibiotics and childhood asthma and allergic rhinitis: a retrospective cohort study

Authors: Richards, M; Ferber, J; Swor, E; Frescholtz, T; Li, D-K; Darrow, L A

BJOG. 2022 Apr;129(5):722-730. Epub 2021-11-08.

PubMed abstract

Respiratory Viral Infections and Infection Prevention Practices among Women with Acute Respiratory Illness during Delivery Hospitalizations during the 2019-2020 Influenza Season

Authors: Dawood, Fatimah S; Li, De-Kun; Campbell, Angela P; et al.

J Infect Dis. 2022 01 05;225(1):50-54.

PubMed abstract

Prevalence of prescription opioid use during pregnancy in 8 U.S. health plans during 2001-2014

Authors: Pocobelli, Gaia; Li, De-Kun; Boudreau, Denise M; et al.

Pharmacoepidemiol Drug Saf. 2021 11;30(11):1541-1550. Epub 2021-07-07.

PubMed abstract

Editorial Expression of Concern: Exposure to Magnetic Field Non-Ionizing Radiation and the Risk of Miscarriage: A Prospective Cohort Study

Authors: Li DK; Chen H; Ferber JR; Odouli R; Quesenberry C

Sci Rep. 2021 03 10;11(1):6021. Epub 2021-03-10.

PubMed abstract

Notice of Retraction and Replacement. Li et al. Association Between Maternal Exposure to Magnetic Field Nonionizing Radiation During Pregnancy and Risk of Attention-Deficit/Hyperactivity Disorder in Offspring in a Longitudinal Birth Cohort. JAMA Netw Open. 2020;3(3):e201417

Authors: Li DK

JAMA Netw Open. 2021 Feb 01;4(2):e2033605. Epub 2021-02-01.

PubMed abstract

Validity of diagnosis and procedure codes for identifying neural tube defects in infants

Authors: Cheetham, T Craig; Li, De-Kun; Boudreau, Denise M; et al.

Pharmacoepidemiol Drug Saf. 2020 11;29(11):1489-1493. Epub 2020-09-15.

PubMed abstract

Cesarean Delivery and the Risk of Allergic Rhinitis in Children

Authors: Richards M; Ferber J; Li DK; Darrow LA

Ann Allergy Asthma Immunol. 2020 09;125(3):280-286.e5. Epub 2020-05-06.

PubMed abstract

Cesarean Delivery and the Risk of Atopic Dermatitis in Children

Authors: Richards M; Ferber J; Chen H; Swor E; Quesenberry CP; Li DK; Darrow LA

Clin Exp Allergy. 2020 07;50(7):805-814. Epub 2020-06-11.

PubMed abstract

Prenatal bisphenol A exposure, fetal thyroid hormones and neurobehavioral development in children at 2 and 4 years: A prospective cohort study

Authors: Li F; Yang F; Li DK; Tian Y; Miao M; Zhang Y; Ji H; Yuan W; Liang H

Sci Total Environ. 2020 Jun 20;722:137887. Epub 2020-03-12.

PubMed abstract

Prenatal Depression and Diet Quality During Pregnancy

Authors: Avalos LA; Caan B; Nance N; Zhu Y; Li DK; Quesenberry C; Hyde RJ; Hedderson MM

J Acad Nutr Diet. 2020 06;120(6):972-984. Epub 2020-02-13.

PubMed abstract

Maternal infection and antibiotic use in pregnancy and the risk of childhood obesity in offspring: a birth cohort study

Authors: Li DK; Chen H; Ferber J; Odouli R

Int J Obes (Lond). 2020 04;44(4):771-780. Epub 2019-12-05.

PubMed abstract

Association Between Maternal Exposure to Magnetic Field Nonionizing Radiation During Pregnancy and Risk of Attention-Deficit/Hyperactivity Disorder in Offspring in a Longitudinal Birth Cohort

Authors: Li DK; Chen H; Ferber JR; Hirst AK; Odouli R

JAMA Netw Open. 2020 03 02;3(3):e201417. Epub 2020-03-02.

PubMed abstract

Trivalent inactivated influenza vaccine (IIV3) during pregnancy and six-month infant development

Authors: Avalos LA; Zerbo O; Li DK; et al.

Vaccine. 2020 02 28;38(10):2326-2332. Epub 2020-02-05.

PubMed abstract

Factors associated with recruitment, surveillance participation, and retention in an observational study of pregnant women and influenza

Authors: Thompson MG; Li DK; Bozeman S; et al.

BMC Pregnancy Childbirth. 2019 May 08;19(1):161. Epub 2019-05-08.

PubMed abstract

Preventing Perinatal Depression to Improve Maternal and Child Health-a Health Care Imperative

Authors: Avalos LA; Flanagan T; Li DK

JAMA Pediatr. 2019 04 01;173(4):313-314.

PubMed abstract

Pregnancy-Associated Cancer: A U.S. Population-Based Study

Authors: Cottreau CM; Dashevsky I; Andrade SE; Li DK; Nekhlyudov L; Raebel MA; Ritzwoller DP; Partridge AH; Pawloski PA; Toh S

J Womens Health (Larchmt). 2019 02;28(2):250-257. Epub 2018-10-10.

PubMed abstract

Prenatal exposure to extremely low frequency magnetic field and its impact on fetal growth

Authors: Ren Y; Chen J; Miao M; Li DK; Liang H; Wang Z; Yang F; Sun X; Yuan W

Environ Health. 2019 01 11;18(1):6. Epub 2019-01-11.

PubMed abstract

Bisphenol A Exposure and Sperm ACHE Hydroxymethylation in Men

Authors: Song X; Miao M; Zhou X; Li D; Tian Y; Liang H; Li R; Yuan W

Int J Epidemiol. 2019 04 01;48(2):423-432.

PubMed abstract

Bisphenol A and pubertal height growth in school-aged children

Authors: Wang Z; Liang H; Tu X; Yuan W; Zhou Z; Jin L; Miao M; Li DK

J Expo Sci Environ Epidemiol. 2019 01;29(1):109-117. Epub 2018-09-05.

PubMed abstract

Maternal exposure to bisphenol A and anogenital distance throughout infancy: A longitudinal study from Shanghai, China

Authors: Sun X; Li D; Liang H; Miao M; Song X; Wang Z; Zhou Z; Yuan W

Environ Int. 2018 12;121(Pt 1):269-275. Epub 2018-09-14.

PubMed abstract

Continuation of postmenopausal hormone replacement therapy: comparison of cyclic versus continuous combined schedules

Authors: Ettinger B; Li DK; Klein R

Menopause. 2018 11;25(11):1187-1190.

PubMed abstract

Association of Bisphenol A Exposure with LINE-1 Hydroxymethylation in Human Semen

Authors: Tian Y; Zhou X; Miao M; Li DK; Wang Z; Li R; Liang H; Yuan W

Int J Environ Res Public Health. 2018 Aug 17;15(8). Epub 2018-08-17.

PubMed abstract

Association between paternal alcohol consumption before conception and anogenital distance of offspring

Authors: Xia R; Jin L; Li D; Liang H; Yang F; Chen J; Yuan W; Miao M

Alcohol Clin Exp Res. 2018 Apr;42(4):735-742. Epub 2018-02-14.

PubMed abstract

Exposure to Magnetic Field Non-Ionizing Radiation and the Risk of Miscarriage: A Prospective Cohort Study

Authors: Li DK; Chen H; Ferber JR; Odouli R; Quesenberry C

Sci Rep. 2017 12 13;7(1):17541. Epub 2017-12-13.

PubMed abstract

Urinary bisphenol A and pubertal development in Chinese school-aged girls: a cross-sectional study

Authors: Miao M; Wang Z; Liu X; Liang H; Zhou Z; Tan H; Yuan W; Li DK

Environ Health. 2017 07 27;16(1):80. Epub 2017-07-27.

PubMed abstract

The impact of high apparent temperature on spontaneous preterm delivery: a case-crossover study

Authors: Avalos LA; Chen H; Li DK; Basu R

Environ Health. 2017 Feb 01;16(1):5. Epub 2017-02-01.

PubMed abstract

The impact of maternal factors on the association between temperature and preterm delivery

Authors: Basu R; Chen H; Li DK; Avalos LA

Environ Res. 2017 Jan 02;154:109-114. Epub 2017-01-02.

PubMed abstract

Urine bisphenol A and pubertal development in boys

Authors: Wang Z; Li D; Miao M; Liang H; Chen J; Zhou Z; Wu C; Yuan W

Int J Hyg Environ Health. 2017 Jan;220(1):43-50. Epub 2016-10-15.

PubMed abstract

Genome-wide alteration in DNA hydroxymethylation in the sperm from bisphenol A-exposed men

Authors: Zheng H; Zhou X; Li DK; Yang F; Pan H; Li T; Miao M; Li R; Yuan W

PLoS ONE. 2017;12(6):e0178535. Epub 2017-06-05.

PubMed abstract

Infection and antibiotic use in infancy and risk of childhood obesity: a longitudinal birth cohort study

Authors: Li DK; Chen H; Ferber J; Odouli R

Lancet Diabetes Endocrinol. 2017 Jan;5(1):18-25. Epub 2016-11-01.

PubMed abstract

The Kaiser Permanente Northern California research program on genes, environment, and health (RPGEH) pregnancy cohort: study design, methodology and baseline characteristics

Authors: Hedderson MM; Ferrara A; Avalos LA; Van den Eeden SK; Gunderson EP; Li DK; Schaefer C; Croen LA; et al.

BMC Pregnancy Childbirth. 2016 Nov 29;16(1):381. Epub 2016-11-29.

PubMed abstract

Effects of maternal folic acid supplementation on gene methylation and being small for gestational age

Authors: Qian YY; Li DK; et al.

J Hum Nutr Diet. 2016 Oct;29(5):643-51. Epub 2016-05-27.

PubMed abstract

Trimethoprim-sulfonamide use during the first trimester of pregnancy and the risk of congenital anomalies

Authors: Hansen C; Li DK; Davis R; et al.

Pharmacoepidemiol Drug Saf. 2016 Feb;25(2):170-8. Epub 2015-Nov-24.

PubMed abstract

Altered Gut Microbiota Composition Associated with Eczema in Infants

Authors: Zheng H; Liang H; Wang Y; Miao M; Shi T; Yang F; Liu E; Yuan W; Ji ZS; Li DK

PLoS ONE. 2016;11(11):e0166026. Epub 2016-11-03.

PubMed abstract

Relationship between self-reported residential indoor remodeling and semen quality: a case-control study

Authors: Miao MH; Li Z; Li DK; Yan B; Liang H; Zhi EL; Du HW; Yuan W

Asian J Androl. 2015 Nov-Dec;17(6):981-4.

PubMed abstract

Associations between Bisphenol A Exposure and Reproductive Hormones among Female Workers

Authors: Miao M; Yuan W; Yang F; Liang H; Zhou Z; Li R; Gao E; Li DK

Int J Environ Res Public Health. 2015 Oct;12(10):13240-50. Epub 2015-10-22.

PubMed abstract

Results of a Pilot Study using Self-Collected Mid-Turbinate Nasal Swabs for Detection of Influenza Virus Infection among Pregnant Women

Authors: Thompson MG; Ferber JR; Odouli R; David D; Shifflett P; Meece JK; Naleway AL; Bozeman S; Spencer SM; Fry AM; Li DK

Influenza Other Respir Viruses. 2015 May;9(3):155-60.

PubMed abstract

Maternal caffeine intake during pregnancy and risk of obesity in offspring: a prospective cohort study

Authors: Li DK; Ferber JR; Odouli R

Int J Obes (Lond). 2015 Apr;39(4):658-64. Epub 2014-11-12.

PubMed abstract

Topiramate use during pregnancy and major congenital malformations in multiple populations

Authors: Tennis P; Li DK; Esposito DB; et al.

Birth Defects Res Part A Clin Mol Teratol. 2015 Apr;103(4):269-75. Epub 2015-03-16.

PubMed abstract

Exposure to bisphenol-A and reproductive hormones among male adults

Authors: Liu X; Miao M; Zhou Z; Gao E; Chen J; Wang J; Sun F; Yuan W; Li DK

Environ Toxicol Pharmacol. 2015 Mar;39(2):934-41. Epub 2015-03-14.

PubMed abstract

Severity of influenza and non-influenza acute respiratory illness among pregnant women, 2010-12

Authors: Sokolow LZ; Naleway AL; Li DK; Shifflett P; Reynolds S; Henninger ML; Ferber JR; Odouli R; Irving SA; Thompson MG; Pregnancy and Influenza Project Workgroup

Am J Obstet Gynecol. 2015 Feb;212(2):202.e1-11. Epub 2014-08-08.

PubMed abstract

Antidepressant medication use, depression, and the risk of preeclampsia

Authors: Avalos LA; Chen H; Li DK

CNS Spectr. 2015 Feb;20(1):39-47.

PubMed abstract

Infections Requiring Hospitalization as Predictors of Pediatric-Onset Crohn’s Disease and Ulcerative Colitis

Authors: Hutfless S; Abramson O; Heyman MB; Bayless TM; Li DK; Winthrop K; Herrinton LJ

Gastroenterol Res Pract. 2015;2015:690581. Epub 2015-05-14.

PubMed abstract

Genital herpes and its treatment in relation to preterm delivery

Authors: Li DK; Raebel MA; Cheetham TC; Hansen C; Avalos L; Chen H; Davis R

Am J Epidemiol. 2014 Dec 1;180(11):1109-17. Epub 2014-11-12.

PubMed abstract

Topiramate use in pregnancy and the birth prevalence of oral clefts

Authors: Mines D; Li DK; Chan KA; et al.

Pharmacoepidemiol Drug Saf. 2014 Oct;23(10):1017-25. Epub 2014-04-01.

PubMed abstract

Volume and Type of Alcohol During Early Pregnancy and the Risk of Miscarriage

Authors: Avalos LA; Roberts SC; Kaskutas LA; Block G; Li DK

Subst Use Misuse. 2014 Sep;49(11):1437-45. Epub 2014-05-08.

PubMed abstract

Safety of influenza vaccination during pregnancy: A review of subsequent maternal obstetric events and findings from two recent cohort studies

Authors: Naleway AL; Irving SA; Henninger ML; Li DK; Shifflett P; Ball S; Williams JL; Cragan J; Gee J; Thompson MG; Vaccine Safety Datalink and Pregnancy and Influenza Project

Vaccine. 2014 May 30;32(26):3122-7. Epub 2014-04-14.

PubMed abstract

Does antidepressant exposure in pregnancy affect maternal serum markers for aneuploidy?

Authors: Schroeder C; Wu D; Merchant M; Ferber J; Currier R; Li DK

Obstet Gynecol. 2014 May;123 Suppl 1:77S-8S.

PubMed abstract

Oral Bisphenol A (BPA) given to rats at moderate doses is associated with erectile dysfunction, cavernosal lipofibrosis and alterations of global gene transcription

Authors: Kovanecz I; Gelfand R; Masouminia M; Gharib S; Segura D; Vernet D; Rajfer J; Li DK; Kannan K; Gonzalez-Cadavid NF

Int J Impot Res. 2014 Mar-Apr;26(2):67-75. Epub 2013-12-05.

PubMed abstract

Brief report: risk of adverse fetal outcomes associated with immunosuppressive medications for chronic immune-mediated diseases in pregnancy

Authors: Cooper WO; Cheetham TC; Li DK; Stein CM; Callahan ST; Morgan TM; Shintani AK; Chen N; Griffin MR; Ray WA

Arthritis Rheumatol. 2014 Feb;66(2):444-50.

PubMed abstract

Effectiveness of seasonal trivalent influenza vaccine for preventing influenza virus illness among pregnant women: a population-based case-control study during the 2010-2011 and 2011-2012 influenza seasons

Authors: Thompson MG; Li DK; Avalos LA; Pregnancy and Influenza Project Workgroup; et al.

Clin Infect Dis. 2014 Feb;58(4):449-57. Epub 2013-11-26.

PubMed abstract

Racial and Ethnic Differences in Health Care Utilization and Outcomes Among Ulcerative Colitis Patients in an Integrated Health-Care Organization

Authors: Li D; Collins B; Velayos FS; Liu L; Lewis JD; Allison JE; Flowers NT; Hutfless S; Abramson O; Herrinton LJ

Dig Dis Sci. 2014 Feb;59(2):287-94. Epub 2013-10-31.

PubMed abstract

Correlation between Exposure to Magnetic Fields and Embryonic Development in the First Trimester

Authors: Su XJ; Yuan W; Tan H; Liu XY; Li D; Li DK; Huang GY; Zhang LW; Miao MH

PLoS ONE. 2014;9(6):e101050. Epub 2014-06-30.

PubMed abstract

LINE-1 hypomethylation in spermatozoa is associated with Bisphenol A exposure

Authors: Miao M; Zhou X; Li Y; Zhang O; Zhou Z; Li T; Yuan W; Li R; Li DK

Andrology. 2014 Jan;2(1):138-44. Epub 2013-12-01.

PubMed abstract

The Prevalence and Trends of Antiviral Medication Use During Pregnancy in the US: A Population-Based Study of 664,297 Deliveries in 2001-2007

Authors: Avalos LA; Li DK; et al.

Matern Child Health J. 2014 Jan;18(1):64-72.

PubMed abstract

Chronic High Dose Intraperitoneal Bisphenol A (BPA) Induces Substantial Histological and Gene Expression Alterations in Rat Penile Tissue Without Impairing Erectile Function

Authors: Kovanecz I; Gelfand R; Masouminia M; Gharib S; Segura D; Vernet D; Rajfer J; Li DK; Liao CY; Kannan K; Gonzalez-Cadavid NF

J Sex Med. 2013 Dec;10(12):2952-66. Epub 2013-10-17.

PubMed abstract

Medication Exposure in Pregnancy Risk Evaluation Program: The Prevalence of Asthma Medication Use During Pregnancy

Authors: Hansen C; Li DK; Davis R; et al.

Matern Child Health J. 2013 Nov;17(9):1611-21.

PubMed abstract

Methods of linking mothers and infants using health plan data for studies of pregnancy outcomes

Authors: Johnson KE; Li DK; Dublin S; et al.

Pharmacoepidemiol Drug Saf. 2013 Jul;22(7):776-82. Epub 2013-04-18.

PubMed abstract

Prevalence and trends in the use of antipsychotic medications during pregnancy in the U.S., 2001-2007: a population-based study of 585,615 deliveries

Authors: Toh S; Li DK; Avalos LA; Andrade SE; et al.

Arch Womens Ment Health. 2013 Apr;16(2):149-57. Epub 2013 Feb 7.

PubMed abstract

Validity of health plan and birth certificate data for pregnancy research

Authors: Andrade SE; Li DK; Cooper WO; et al.

Pharmacoepidemiol Drug Saf. 2013 Jan;22(1):7-15. Epub 2012 Jul 3.

PubMed abstract

Urine bisphenol-a level in relation to obesity and overweight in school-age children

Authors: Li DK; Miao M; Zhou Z; Wu C; Shi H; Liu X; Wang S; Yuan W

PLoS ONE. 2013;8(6):e65399. Epub 2013-06-12.

PubMed abstract

Trends in the Use of Antiepileptic Drugs among Pregnant Women in the US, 2001-2007: A Medication Exposure in Pregnancy Risk Evaluation Program Study

Authors: Bobo WV; Li DK; Avalos LA; Cooper WO; et al.

Paediatr Perinat Epidemiol. 2012 Nov;26(6):578-88.

PubMed abstract

A Large, Population-Based Study of 2009 Pandemic Influenza A Virus Subtype H1N1 Infection Diagnosis During Pregnancy and Outcomes for Mothers and Neonates

Authors: Hansen C; Desai S; Bredfeldt C; Cheetham C; Gallagher M; Li DK; Raebel MA; Riedlinger K; Shay DK; Thompson M; Davis RL

J Infect Dis. 2012 Oct;206(8):1260-8. Epub 2012 Aug 2.

PubMed abstract

Prenatal and Perinatal Characteristics Associated with Pediatric-Onset Inflammatory Bowel Disease

Authors: Hutfless S; Li DK; Heyman MB; Bayless TM; Abramson O; Herrinton LJ

Dig Dis Sci. 2012 Aug;57(8):2149-56. Epub 2012 Mar 24.

PubMed abstract

A Prospective Study of In-utero Exposure to Magnetic Fields and the Risk of Childhood Obesity

Authors: Li DK; Ferber JR; Odouli R; Quesenberry CP Jr

Sci Rep. 2012;2:540. Epub 2012 Jul 27.

PubMed abstract

Does Lack of Multinutrient Supplementation During Early Pregnancy Increase Vulnerability to Alcohol-Related Preterm or Small-for-Gestational-Age Births?

Authors: Avalos LA; Kaskutas L; Block G; Abrams B; Li DK

Matern Child Health J. 2011 Nov;15(8):1324-32.

PubMed abstract

In utero exposure to bisphenol-A and anogenital distance of male offspring

Authors: Miao M; Yuan W; He Y; Zhou Z; Wang J; Gao E; Li G; Li DK

Birth Defects Res A Clin Mol Teratol. 2011 Oct;91(10):867-72. Epub 2011 Aug 26.

PubMed abstract

Maternal exposure to magnetic fields during pregnancy in relation to the risk of asthma in offspring

Authors: Li DK; Chen H; Odouli R

Arch Pediatr Adolesc Med. 2011 Oct;165(10):945-50. Epub 2011 Aug 1.

PubMed abstract

In utero exposure to bisphenol-A and its effect on birth weight of offspring

Authors: Miao M; Yuan W; Zhu G; He X; Li DK

Reprod Toxicol. 2011 Jul;32(1):64-8. Epub 2011 Mar 31.

PubMed abstract

The Pregnancy and Influenza Project: design of an observational case-cohort study to evaluate influenza burden and vaccine effectiveness among pregnant women and their infants

Authors: Thompson M; Williams J; Naleway A; Li DK; Chu S; Bozeman S; Hill HA; Cragan J; Shay DK; Pregnancy and Influenza Project Workgroup

Am J Obstet Gynecol. 2011 Jun;204(6 Suppl 1):S69-76. Epub 2011 Mar 16.

PubMed abstract

Does antiviral medication for treating herpes simplex during pregnancy increase the risk of birth defects in offspring?

Authors: Li DK

Evid Based Med. 2011 Feb;16(1):30. Epub 2010 Nov 25.

PubMed abstract

Urine bisphenol-A (BPA) level in relation to semen quality

Authors: Li DK; Zhou Z; Miao M; He Y; Wang J; Ferber J; Herrinton LJ; Gao E; Yuan W

Fertil Steril. 2011 Feb;95(2):625-30.e1-4. Epub 2010 Oct 29.

PubMed abstract

Maternal exposure to angiotensin converting enzyme inhibitors in the first trimester and risk of malformations in offspring: a retrospective cohort study

Authors: Li DK; Yang C; Andrade S; Tavares V; Ferber JR

BMJ. 2011 Oct 18;343:d5931.

PubMed abstract

Relationship between urine bisphenol-A level and declining male sexual function

Authors: Li DK; Yuan W; et al.

J Androl. 2010 Sep-Oct;31(5):500-6. Epub 2010 May 13.

PubMed abstract

Occupational exposure to bisphenol-A (BPA) and the risk of self-reported male sexual dysfunction

Authors: Li D; Yuan W; et al.

Hum Reprod. 2010 Feb;25(2):519-27. Epub 2009 Nov 10.

PubMed abstract

Exposure to magnetic fields and the risk of poor sperm quality

Authors: Li DK; Yan B; Li Z; Gao E; Miao M; Gong D; Weng X; Ferber JR; Yuan W

Reprod Toxicol. 2010 Jan;29(1):86-92. Epub 2009 Nov 6.

PubMed abstract

Do multivitamin supplements modify the relationship between prenatal alcohol intake and miscarriage?

Authors: Ammon Avalos L; Kaskutas LA; Block G; Li DK

Am J Obstet Gynecol. 2009 Dec;201(6):563.e1-9. Epub 2009 Oct 20.

PubMed abstract

Bisphenol A levels in blood and urine in a Chinese population and the personal factors affecting the levels

Authors: He Y; Miao M; Herrinton LJ; Wu C; Yuan W; Zhou Z; Li DK

Environ Res. 2009 Jul;109(5):629-33. Epub 2009 May 8.

PubMed abstract

Presence of depressive symptoms during early pregnancy and the risk of preterm delivery: a prospective cohort study

Authors: Li D; Liu L; Odouli R

Hum Reprod. 2009 Jan;24(1):146-53. Epub 2008 Oct 23.

PubMed abstract

Occupational exposure levels of bisphenol A among Chinese workers

Authors: He Y; Miao M; Wu C; Yuan W; Gao E; Zhou Z; Li DK

J Occup Health. 2009;51(5):432-6. Epub 2009 Aug 25.

PubMed abstract

Factors influencing women’s acceptance of prenatal screening tests

Authors: Li DK; Karlberg K; Wi S; Norem C

Prenat Diagn. 2008 Dec;28(12):1136-43.

PubMed abstract

Use of a fan during sleep and the risk of sudden infant death syndrome

Authors: Coleman-Phox K; Odouli R; Li DK

Arch Pediatr Adolesc Med. 2008 Oct;162(10):963-8.

PubMed abstract

Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study

Authors: Weng X; Odouli R; Li DK

Am J Obstet Gynecol. 2008 Mar;198(3):279.e1-8. Epub 2008 Jan 25.

PubMed abstract

Pregnancy outcomes in women with inflammatory bowel disease: a large community-based study from Northern California

Authors: Mahadevan U; Sandborn WJ; Li DK; Hakimian S; Kane S; Corley DA

Gastroenterology. 2007 Oct;133(4):1106-12. Epub 2007 Jul 25.

PubMed abstract

Use of a dummy (pacifier) during sleep and risk of sudden infant death syndrome (SIDS): population based case-control study

Authors: Li DK; Willinger M; Petitti DB; Odouli R; Liu L; Hoffman HJ

BMJ. 2006 Jan 7;332(7532):18-22. Epub 2005 Dec 9.

PubMed abstract

Transmission of parentally shared human leukocyte antigen alleles and the risk of preterm delivery

Authors: Li DK; Odouli R; Liu L; Vinson M; Trachtenberg E

Obstet Gynecol. 2004 Sep;104(3):594-600.

PubMed abstract

Hot tub use during pregnancy and the risk of miscarriage

Authors: Li DK; Janevic T; Odouli R; Liu L

Am J Epidemiol. 2003 Nov 15;158(10):931-7.

PubMed abstract

Exposure to non-steroidal anti-inflammatory drugs during pregnancy and risk of miscarriage: population based cohort study

Authors: Li DK; Liu L; Odouli R

BMJ. 2003 Aug 16;327(7411):368.

PubMed abstract

Infant sleeping position and the risk of sudden infant death syndrome in California, 1997-2000

Authors: Li DK; Petitti DB; Willinger M; McMahon R; Odouli R; Vu H; Hoffman HJ

Am J Epidemiol. 2003 Mar 1;157(5):446-55.

PubMed abstract

A population-based prospective cohort study of personal exposure to magnetic fields during pregnancy and the risk of miscarriage

Authors: Li DK; Odouli R; Wi S; Janevic T; Golditch I; Bracken TD; Senior R; Rankin R; Iriye R

Epidemiology. 2002 Jan;13(1):9-20.

PubMed abstract

Neonatal sepsis workups in infants >/=2000 grams at birth: A population-based study

Authors: Escobar GJ; Li DK; Armstrong MA; Gardner MN; Folck BF; Verdi JE; Xiong B; Bergen R

Pediatrics. 2000 Aug;106(2 Pt 1):256-63.

PubMed abstract

Maternal pre-eclampsia/eclampsia and the risk of sudden infant death syndrome in offspring

Authors: Li DK; Wi S

Paediatr Perinat Epidemiol. 2000 Apr;14(2):141-4.

PubMed abstract

Changing paternity and the risk of preeclampsia/eclampsia in the subsequent pregnancy

Authors: Li DK; Wi S

Am J Epidemiol. 2000 Jan 1;151(1):57-62.

PubMed abstract

Maternal placental abnormality and the risk of sudden infant death syndrome

Authors: Li DK; Wi S

Am J Epidemiol. 1999 Apr 1;149(7):608-11.

PubMed abstract

Changing paternity and the risk of preterm delivery in the subsequent pregnancy

Authors: Li DK

Epidemiology. 1999 Mar;10(2):148-52.

PubMed abstract

Maternal history of subfertility and the risk of congenital urinary tract anomalies in offspring

Authors: Li DK

Epidemiology. 1999 Jan;10(1):80-2.

PubMed abstract

Transient neurologic symptoms after spinal anesthesia: an epidemiologic study of 1,863 patients

Authors: Freedman JM; Li DK; Drasner K; Jaskela MC; Larsen B; Wi S

Anesthesiology. 1998 Sep;89(3):633-41.

PubMed abstract

Unexpected vaginal bleeding and associated gynecologic care in postmenopausal women using hormone replacement therapy: comparison of cyclic versus continuous combined schedules

Authors: Ettinger B; Li DK; Klein R

Fertil Steril. 1998 May;69(5):865-9.

PubMed abstract

Related Stories

Study in pregnant women suggests maternal infection, not antibiotics, associated with childhood obesity

Study in pregnant women suggests maternal infection, not antibiotics, associated with childhood obesity

December 5, 2019

Women who had an untreated infection during pregnancy were more likely to have a child who later went on to be obese than pregnant women who never had an infection, new research from Kaiser Permanente finds.
Our Team
Back To Top