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Romain S. Neugebauer, PhD

romain.s.neugebauer@kp.org

Kaiser Permanente Researcher Profiles

Romain  Neugebauer, PhD

Romain S. Neugebauer, PhD, is a research scientist at the Kaiser Permanente Northern California Division of Research. His research focuses on the development, application, and dissemination of statistical methodologies to evaluate treatment effects in randomized experiments and observational studies. His particular interest is in causal methods to evaluate the effects of treatment regimens with complex longitudinal data. Prior to joining the Division of Research, Dr. Neugebauer was a researcher and lecturer in the School of Public Health at the University of California, Berkeley where he also received his PhD in biostatistics.

Current Positions

  • Research Scientist III, Division of Research, Kaiser Permanente Northern California

Section Affiliations

Related Websites

Studies

Comparison of type 2 diabetes pharmacotherapy regimens using targeted learning

This study is designed to help patients with type 2 diabetes and their clinicians identify which glucose-lowering medications among SGLT2 inhibitors, GLP-1 receptor agonists, DPP4 inhibitors, or Sulfonylureas have the most favorable effects on heart health and other patient-important outcomes; inform the timing of medication initiation; and explore whether medication benefits apply equally to all adults with type 2 diabetes, or are different based on age, sex, race/ethnicity, baseline heart health status, baseline renal function, or other factors. Inferences are based on a modern causal inference methodology, Targeted Learning, applied within a trial emulation framework.

Investigator: Neugebauer, Romain

Funder: Patient-Centered Outcomes Research Institute

Leveraging Machine Learning to Improve Risk Prediction for Chemotherapy Induced Neuropathy

Chemotherapy-associated peripheral neuropathy (CPN) affects nearly 70% of cancer patients. An estimated 30% of cancer survivors have persistent CPN, which can have a devastating impact on their quality of life and functioning. Our objective is to develop and validate a predictive model that will identify those patients who are at high risk of developing severe CPN that can result in their receiving fewer planned chemotherapy cycles. We will focus on two subgroups our preliminary studies suggest have a higher risk for CPN: people who have diabetes or are African American/ Black.

Investigator: Neugebauer, Romain

Funder: National Cancer Institute

Evaluation of Complex Interventions on Drug (Re)Fill Behavior Using Electronic Health Care Data

This study develops generalized per-protocol analyses based on Inverse Probability Weighting and Targeted Learning to control for or evaluate the effect of medication nonadherence in observational studies that use electronic health databases to inform the management of chronic conditions. Unlike current implementations of these analyses that require investigators to make untestable and often arbitrary assumptions regarding patients’ use of drugs from pharmacy dispensing data, the proposed causal methodologies directly evaluate the health effects of drug (re)fill regimens. To develop these analytic approaches, we seek guidance from stakeholder partners representing a broad range of constituencies to illustrate and ensure the practical relevance of the proposed methods from two prior studies with electronic health databases conducted to inform the management of type 2 diabetes.

Investigator: Neugebauer, Romain

Funder: Patient-Centered Outcomes Research Institute

Software to Automate Implementation of Causal Inference Methods with Time-Varying Interventions

This project aims to develop SAS macros to automate the data structuring required for implementation of Causal Inference methods with electronic health records data in studies with time-varying exposures, confounding and selection bias (e.g., marginal structural modeling with inverse probability weighting). SAS macros are validated with simulated data and their applicability is evaluated using secondary data analyses in cardiovascular, diabetes, and health services research. End-user feedback is used to validate and refine the implementation and documentation of the SAS software.  

Investigator: Neugebauer, Romain

Feasibility and Performance Assessments of TMLE and hdPS Methodologies to Fit MSM in a Real-World CER Study

This study aims to evaluate the practicability and practical advantages of: 1) Targeted Minimum Loss based Estimation (TMLE), and 2) a high-dimensional propensity score (hdPS) algorithm to fit dynamic Marginal Structural Models (MSM) in a longitudinal comparative effectiveness research (CER) study of adults with type 2 diabetes. 

Investigator: Neugebauer, Romain

Funder: Agency for Healthcare Research and Quality

Causal Analyses of Electronic Health Record Data for Assessing the Comparative Effectiveness of Treatment Regimens

This study aims to strengthen causal inferences based on Marginal Structural Modeling (MSM) and large healthcare databases for Comparative Effectiveness Research in Type 2 Diabetes Mellitus (T2DM), specifically, it aims to: 1) Develop a consensus for the types and quantity of MSM parameters relevant to T2DM patients and other stakeholders; 2) Evaluate the feasibility and performance of MSM approaches based on Targeted Learning to estimate these MSM parameters more efficiently and with more robustness to modeling assumptions than the current Inverse Probability Weighting approaches; 3) Explore the biases that may arise from current MSM applications with data where patient monitoring is not fixed but random or where the outcome is not right-censored but interval-censored and evaluate innovative MSM methods that aim to address these biases.

Investigator: Neugebauer, Romain

Funder: Patient-Centered Outcomes Research Institute

Publications

Development of cardiometabolic risk factors following endocrine therapy in women with breast cancer

Authors: Rillamas-Sun, Eileen;Kwan, Marilyn L;Cheng, Richard;Neugebauer, Romain;Rana, Jamal S;Hershman, Dawn L;Greenlee, Heather;et al.

Breast Cancer Res Treat. 2023 Aug;201(1):117-126. Epub 2023-06-16.

PubMed abstract

A comparative effectiveness study of carotid intervention for long-term stroke prevention in patients with severe asymptomatic stenosis from a large integrated health system

Authors: Chang, Robert W;Pimentel, Noel;Tucker, Lue-Yen;Rothenberg, Kara A;Avins, Andrew L;Flint, Alexander C;Faruqi, Rishad M;Nguyen-Huynh, Mai N;Neugebauer, Romain

J Vasc Surg. 2023 Jul 04.

PubMed abstract

Development of cardiometabolic risk factors following endocrine therapy in women with breast cancer

Authors: Rillamas-Sun, Eileen; Kwan, Marilyn L; Iribarren, Carlos; Neugebauer, Romain; Rana, Jamal S; Nguyen-Huynh, Mai; Kushi, Lawrence H; Greenlee, Heather; et al.

Res Sq. 2023 Mar 22.

PubMed abstract

Practice Patterns and Outcomes Associated With Anticoagulation Use Following Sepsis Hospitalizations With New-Onset Atrial Fibrillation

Authors: Walkey, Allan J; Myers, Laura C; Thai, Khanh K; Kipnis, Patricia; Desai, Manisha; Go, Alan S; Lu, Yun; Clancy, Heather; Devis, Ycar; Neugebauer, Romain; Liu, Vincent X

Circ Cardiovasc Qual Outcomes. 2023 Mar;16(3):e009494. Epub 2023-02-28.

PubMed abstract

Maternal and neonatal outcomes associated with treating hypertension in pregnancy at different thresholds

Authors: Avalos, Lyndsay A; Neugebauer, Romain S; Nance, Nerissa; Badon, Sylvia E; Cheetham, T Craig; Easterling, Thomas R; Reynolds, Kristi; Idu, Abisola; Bider-Canfield, Zoe; Holt, Victoria L; Dublin, Sascha

Pharmacotherapy. 2023 Feb 13.

PubMed abstract

High-dimensional propensity scores for empirical covariate selection in secondary database studies: Planning, implementation, and reporting

Authors: Rassen, Jeremy A; Blin, Patrick; Kloss, Sebastian; Neugebauer, Romain S; Platt, Robert W; Pottegård, Anton; Schneeweiss, Sebastian; Toh, Sengwee

Pharmacoepidemiol Drug Saf. 2023 Feb;32(2):93-106. Epub 2022-11-22.

PubMed abstract

Risk of Cardiometabolic Risk Factors in Women With and Without a History of Breast Cancer: The Pathways Heart Study

Authors: Kwan, Marilyn L; Iribarren, Carlos; Neugebauer, Romain; Rana, Jamal S; Nguyen-Huynh, Mai; Kushi, Lawrence H; Greenlee, Heather; et al.

J Clin Oncol. 2022 05 20;40(15):1635-1646. Epub 2022-01-13.

PubMed abstract

Risk of Cardiovascular Disease in Women With and Without Breast Cancer: The Pathways Heart Study

Authors: Greenlee, Heather; Rana, Jamal S; Cheng, Richard; Rillamas-Sun, Eileen; Neugebauer, Romain; Kwan, Marilyn L; Kwan, Marilyn L; et al.

J Clin Oncol. 2022 05 20;40(15):1647-1658. Epub 2022-04-06.

PubMed abstract

Association of Glyburide and Subcutaneous Insulin With Perinatal Complications Among Women With Gestational Diabetes

Authors: Hedderson, Monique M; Badon, Sylvia E; Pimentel, Noel; Xu, Fei; Regenstein, Anne; Ferrara, Assiamira; Neugebauer, Romain

JAMA Netw Open. 2022 03 01;5(3):e225026. Epub 2022-03-01.

PubMed abstract

Maternal and neonatal outcomes of antihypertensive treatment in pregnancy: A retrospective cohort study

Authors: Dublin, Sascha; Avalos, Lyndsay A; Neugebauer, Romain S; Badon, Sylvia E; Shortreed, Susan M; et al.

PLoS One. 2022;17(5):e0268284. Epub 2022-05-16.

PubMed abstract

Identifying hypertensive disorders of pregnancy, a comparison of two epidemiologic definitions

Authors: Cheetham, T Craig; Avalos, Lyndsay A; Neugebauer, Romain S; Dublin, Sascha; et al.

Front Cardiovasc Med. 2022;9:1006104. Epub 2022-11-23.

PubMed abstract

Association of Cardiovascular Outcomes and Mortality With Sustained Long-Acting Insulin Only vs Long-Acting Plus Short-Acting Insulin Treatment

Authors: Schroeder, Emily B; Neugebauer, Romain; Schmittdiel, Julie A; O'Connor, Patrick J; et al.

JAMA Netw Open. 2021 09 01;4(9):e2126605. Epub 2021-09-01.

PubMed abstract

Separating Algorithms from Questions and Causal Inference with Unmeasured Exposures: An Application to Birth Cohort Studies of Early BMI Rebound

Authors: Aris, Izzuddin M; Sarvet, Aaron L; Stensrud, Mats J; Neugebauer, Romain; Li, Ling-Jun; Hivert, Marie-France; Oken, Emily; Young, Jessica G

Am J Epidemiol. 2021 07 01;190(7):1414-1423.

PubMed abstract

The effect of mail order pharmacy outreach on older patients with diabetes

Authors: Gong, Chelsea; Dyer, Wendy; Yassin, Maher; Neugebauer, Romain; Karter, Andrew J; Schmittdiel, Julie A

J Am Geriatr Soc. 2021 07;69(7):2028-2030. Epub 2021-03-26.

PubMed abstract

Timing of Antiretroviral Therapy Initiation and Risk of Cancer among Persons Living with HIV

Authors: Silverberg, Michael J; Neugebauer, Romain S; et al.

Clin Infect Dis. 2021 06 01;72(11):1900-1909.

PubMed abstract

A prognostic information system for real-time personalized care: Lessons for embedded researchers

Authors: Lieu, Tracy A; Neugebauer, Romain; Van Den Eeden, Stephen K; Baer, David M; et al.

Healthc (Amst). 2021 Jun;8 Suppl 1:100486. Epub 2021-06-23.

PubMed abstract

Is Shelter-in-Place Policy Related to Mail Order Pharmacy Use and Racial/Ethnic Disparities for Patients With Diabetes?

Authors: Thomas, Tainayah W; Dyer, Wendy T; Yassin, Maher; Neugebauer, Romain; Karter, Andrew J; Schmittdiel, Julie A

Diabetes Care. 2021 06;44(6):e113-e114. Epub 2021-04-13.

PubMed abstract

Gestational weight gain and adverse pregnancy outcomes by pre-pregnancy BMI category in women with chronic hypertension: A cohort study

Authors: Badon, Sylvia E; Dublin, Sascha; Nance, Nerissa; Hedderson, Monique M; Neugebauer, Romain; Easterling, Thomas; Cheetham, T Craig; Chen, Lu; Holt, Victoria L; Avalos, Lyndsay A

Pregnancy Hypertens. 2021 Mar;23:27-33. Epub 2020-10-24.

PubMed abstract

Exercise During the First Trimester of Pregnancy and the Risks of Abnormal Screening and Gestational Diabetes Mellitus

Authors: Ehrlich, Samantha F; Ferrara, Assiamira; Hedderson, Monique M; Feng, Juanran; Neugebauer, Romain

Diabetes Care. 2021 02;44(2):425-432. Epub 2020-12-21.

PubMed abstract

A Randomized Encouragement Trial to Increase Mail Order Pharmacy Use and Medication Adherence in Patients with Diabetes

Authors: Ramachandran, Bharathi; Neugebauer, Romain S; Brown, Susan D; Karter, Andrew J; Schmittdiel, Julie A; et al.

J Gen Intern Med. 2021 01;36(1):154-161. Epub 2020-10-01.

PubMed abstract

Risk of complete atypical femur fracture with Oral bisphosphonate exposure beyond three years

Authors: Lo, Joan C; Neugebauer, Romain S; Ettinger, Bruce; Chandra, Malini; Hui, Rita L; Ott, Susan M; Grimsrud, Christopher D; Izano, Monika A

BMC Musculoskelet Disord. 2020 Dec 03;21(1):801. Epub 2020-12-03.

PubMed abstract

Bisphosphonate Treatment Beyond 5 Years and Hip Fracture Risk in Older Women

Authors: Izano, Monika A; Lo, Joan C; Adams, Annette L; Ettinger, Bruce; Ott, Susan M; Chandra, Malini; Hui, Rita L; Niu, Fang; Li, Bonnie H; Neugebauer, Romain S

JAMA Netw Open. 2020 12 01;3(12):e2025190. Epub 2020-12-01.

PubMed abstract

Inpatient-outpatient shared electronic health records: telemedicine and laboratory follow-up after hospital discharge

Authors: Reed, Mary; Huang, Jie; Brand, Richard; Graetz, Ilana; Jaffe, Marc G; Ballard, Dustin; Neugebauer, Romain; Fireman, Bruce; Hsu, John

Am J Manag Care. 2020 10 01;26(10):e327-e332. Epub 2020-10-01.

PubMed abstract

Exploiting nonsystematic covariate monitoring to broaden the scope of evidence about the causal effects of adaptive treatment strategies

Authors: Kreif N; Sofrygin O; Schmittdiel JA; Adams AS; Grant RW; Zhu Z; van der Laan MJ; Neugebauer R

Biometrics. 2020 Apr 15.

PubMed abstract

Association of immunosuppression and HIV viremia with anal cancer risk in persons living with HIV in the United States and Canada

Authors: Hernández-Ramírez RU; Neugebauer RS; Silverberg MJ; North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic Databases to Evaluate AIDS; et al.

Clin Infect Dis. 2020 03 03;70(6):1176-1185.

PubMed abstract

Exercise During the First Trimester and Infant Size at Birth: Targeted Maximum Likelihood Estimation of the Causal Risk Difference

Authors: Ehrlich SF; Neugebauer RS; Feng J; Hedderson MM; Ferrara A

Am J Epidemiol. 2020 02 28;189(2):133-145.

PubMed abstract

Determinants of Oral Bisphosphonate Use Beyond 5 Years

Authors: Izano MA; Lo JC; Ettinger B; Ott SM; Li BH; Niu F; Hui RL; Neugebauer R; Adams AL

J Manag Care Spec Pharm. 2020 Feb;26(2):197-202.

PubMed abstract

Comparison of Mortality and Major Cardiovascular Events Among Adults With Type 2 Diabetes Using Human vs Analogue Insulins

Authors: Neugebauer R; Schmittdiel JA; O'Connor PJ; et al.

JAMA Netw Open. 2020 01 03;3(1):e1918554. Epub 2020-01-03.

PubMed abstract

Identifying hypertension in pregnancy using electronic medical records: The importance of blood pressure values

Authors: Chen L; Avalos LA; Neugebauer R; Badon SE; Dublin S; et al.

Pregnancy Hypertens. 2020 Jan;19:112-118. Epub 2020-01-03.

PubMed abstract

Targeted learning with daily EHR data

Authors: Sofrygin O; Zhu Z; Schmittdiel JA; Adams AS; Grant RW; van der Laan MJ; Neugebauer R

Stat Med. 2019 07 20;38(16):3073-3090. Epub 2019-04-25.

PubMed abstract

Using Pharmacy Data and Adherence to Define Long-Term Bisphosphonate Exposure in Women

Authors: Izano MA; Neugebauer R; Ettinger B; Hui R; Chandra M; Adams AL; Niu F; Ott SM; Lo JC

J Manag Care Spec Pharm. 2019 Jun;25(6):719-723.

PubMed abstract

Association of immunosuppression and HIV viraemia with non-Hodgkin lymphoma risk overall and by subtype in people living with HIV in Canada and the USA: a multicentre cohort study

Authors: Hernández-Ramírez RU; Neugebauer RS; Silverberg MJ; North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic Databases to Evaluate AIDS; et al.

Lancet HIV. 2019 04;6(4):e240-e249. Epub 2019-02-27.

PubMed abstract

Comparative effectiveness of treatment of actinic keratosis with topical fluorouracil and imiquimod in the prevention of keratinocyte carcinoma: a cohort study

Authors: Neugebauer R; Su KA; Zhu Z; Sokil M; Chren MM; Friedman GD; Asgari MM

J Am Acad Dermatol. 2019 Apr;80(4):998-1005. Epub 2018-11-17.

PubMed abstract

Developing a Prognostic Information System for Personalized Care in Real Time

Authors: Lieu TA; Neugebauer R; Van Den Eeden SK; Baer DM; et al.

EGEMS (Wash DC). 2019 Mar 25;7(1):2. Epub 2019-03-25.

PubMed abstract

Automated symptom and treatment side effect monitoring for improved quality of life among adults with diabetic peripheral neuropathy in primary care: a pragmatic, cluster, randomized, controlled trial

Authors: Adams AS; Schmittdiel JA; Neugebauer R; Grant RW; et al.

Diabet Med. 2019 01;36(1):52-61. Epub 2018-11-07.

PubMed abstract

Patients with complex chronic conditions: Health care use and clinical events associated with access to a patient portal

Authors: Reed ME; Huang J; Brand RJ; Neugebauer R; Graetz I; Hsu J; Ballard DW; Grant R

PLoS One. 2019;14(6):e0217636. Epub 2019-06-19.

PubMed abstract

Cutaneous Melanoma Risk among People with HIV in the United States and Canada

Authors: Yanik EL; Neugebauer RS; Silverberg MJ; Dubrow R; et al.

J Acquir Immune Defic Syndr. 2018 08 15;78(5):499-504.

PubMed abstract

A real-world, community-based cohort study comparing the effectiveness of topical fluoruracil vs. topical imiquimod for the treatment of actinic keratosis

Authors: Neugebauer R; Levandoski KA; Zhu Z; Sokil M; Chren MM; Friedman GD; Asgari MM

J Am Acad Dermatol. 2017 Dec 22.

PubMed abstract

Adjuvant gemcitabine-docetaxel chemotherapy for stage I uterine leiomyosarcoma: Trends and survival outcomes

Authors: Littell RD; Tucker LY; Raine-Bennett T; Palen TE; Zaritsky E; Neugebauer R; Embry-Schubert J; Lentz SE

Gynecol Oncol. 2017 10;147(1):11-17. Epub 2017-07-24.

PubMed abstract

Associations of CD4+ T-cell count, HIV-1 RNA viral load, and antiretroviral therapy with Kaposi sarcoma risk among HIV-infected persons in the United States and Canada

Authors: Dubrow R; Neugebauer RS; Silverberg MJ; North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic Databases to Evaluate AIDS; et al.

J Acquir Immune Defic Syndr. 2017 Aug 01;75(4):382-390.

PubMed abstract

Minimally Invasive Hysterectomy and Power Morcellation Trends in a West Coast Integrated Health System

Authors: Zaritsky E; Tucker LY; Neugebauer R; Chou T; Flanagan T; Walter AJ; Raine-Bennett T

Obstet Gynecol. 2017 Jun;129(6):996-1005.

PubMed abstract

Community-Based Practice Variations in Topical Treatment of Actinic Keratoses

Authors: Storer M; Zhu Z; Sokil M; Ford M; Neugebauer R; Asgari MM

JAMA Dermatol. 2017 Apr 05.

PubMed abstract

Identification of the joint effect of a dynamic treatment intervention and a stochastic monitoring intervention under the no direct effect assumption

Authors: Neugebauer R; Schmittdiel JA; Adams AS; Grant RW; van der Laan MJ

J Causal Inference. 2017 03;5(1). Epub 2017-01-18.

PubMed abstract

Telephone-Based Coaching: A Comparison of Tobacco Cessation Programs in an Integrated Health Care System

Authors: Boccio M; Sanna RS; Adams SR; Goler NC; Brown SD; Neugebauer RS; Ferrara A; Wiley DM; Bellamy DJ; Schmittdiel JA

Am J Health Promot. 2017 Mar;31(2):136-142. Epub 2016-11-18.

PubMed abstract

The impact of telephonic wellness coaching on weight loss: A “Natural Experiments for Translation in Diabetes (NEXT-D)” study

Authors: Schmittdiel JA; Adams SR; Goler N; Sanna RS; Boccio M; Bellamy DJ; Brown SD; Neugebauer RS; Ferrara A

Obesity (Silver Spring). 2017 Feb;25(2):352-356.

PubMed abstract

simcausal R Package: Conducting Transparent and Reproducible Simulation Studies of Causal Effect Estimation with Complex Longitudinal Data

Authors: Sofrygin O; van der Laan MJ; Neugebauer R

J Stat Softw. 2017;81. Epub 2017-10-16.

PubMed abstract

Analysis of Body Mass Index and Mortality in Patients With Colorectal Cancer Using Causal Diagrams

Authors: Kroenke CH; Neugebauer R; Meyerhardt J; Prado CM; Weltzien E; Kwan ML; Xiao J; Caan BJ

JAMA Oncol. 2016 Sep 01;2(9):1137-45.

PubMed abstract

The Diabetes Telephone Study: Design and challenges of a pragmatic cluster randomized trial to improve diabetic peripheral neuropathy treatment

Authors: Adams AS; Bayliss EA; Schmittdiel JA; Altschuler A; Dyer W; Neugebauer R; Jaffe M; Young JD; Kim E; Grant RW; Diabetes Telephone Study Team

Clin Trials. 2016 Jun;13(3):286-93. Epub 2016-03-31.

PubMed abstract

A Case Study of the Impact of Data-Adaptive Versus Model-Based Estimation of the Propensity Scores on Causal Inferences from Three Inverse Probability Weighting Estimators

Authors: Neugebauer R; Schmittdiel JA; van der Laan MJ

Int J Biostat. 2016 05 01;12(1):131-55.

PubMed abstract

Use of abacavir and risk of cardiovascular disease among HIV-infected individuals

Authors: Marcus JL; Neugebauer RS; Leyden WA; Chao CR; Xu L; Quesenberry CP; Klein DB; Towner WJ; Horberg MA; Silverberg MJ

J Acquir Immune Defic Syndr. 2016 Apr 1;71(4):413-9.

PubMed abstract

The association of race/ethnicity and risk of atypical femur fracture among older women receiving oral bisphosphonate therapy

Authors: Lo JC; Hui RL; Grimsrud CD; Chandra M; Neugebauer RS; Gonzalez JR; Budayr A; Lau G; Ettinger B

Bone. 2016 Apr;85:142-7. Epub 2016-01-06.

PubMed abstract

Occult Uterine Sarcoma and Leiomyosarcoma: Incidence of and Survival Associated With Morcellation

Authors: Raine-Bennett T; Neugebauer R; Lentz SE; et al.

Obstet Gynecol. 2016 Jan;127(1):29-39.

PubMed abstract

Adherence to Metformin, Statins, and ACE/ARBs Within the Diabetes Health Plan (DHP)

Authors: Duru OK; Neugebauer R; Mangione CM; et al.

J Gen Intern Med. 2015 Nov;30(11):1645-50. Epub 2015-05-06.

PubMed abstract

Employer-Based Screening for Diabetes and Prediabetes in an Integrated Health Care Delivery System: A Natural Experiment for Translation in Diabetes (NEXT-D) Study

Authors: Adams SR; Wiley DM; Fargeix A; George V; Neugebauer RS; Schmittdiel JA

J Occup Environ Med. 2015 Nov;57(11):1147-53.

PubMed abstract

High-dimensional propensity score algorithm in comparative effectiveness research with time-varying interventions

Authors: Neugebauer R; Schmittdiel JA; Zhu Z; Rassen JA; Seeger JD; Schneeweiss S

Stat Med. 2015 Feb 28;34(5):753-81. Epub 2014-12-08.

PubMed abstract

Wellness Coaching for People With Prediabetes: A Randomized Encouragement Trial to Evaluate Outreach Methods at Kaiser Permanente, Northern California, 2013

Authors: Xiao H; Adams SR; Goler N; Sanna RS; Boccio M; Bellamy DJ; Brown SD; Neugebauer RS; Ferrara A; Schmittdiel JA

Prev Chronic Dis. 2015;12:E207. Epub 2015-11-25.

PubMed abstract

Racial/ethnic differences in hip and diaphyseal femur fractures

Authors: Lo JC; Zheng P; Grimsrud CD; Chandra M; Ettinger B; Budayr A; Lau G; Baur MM; Hui RL; Neugebauer R

Osteoporos Int. 2014 Sep;25(9):2313-8. Epub 2014-06-26.

PubMed abstract

Targeted learning in real-world comparative effectiveness research with time-varying interventions

Authors: Neugebauer R; Schmittdiel JA; van der Laan MJ

Stat Med. 2014 Jun 30;33(14):2480-520. Epub 2014-02-17.

PubMed abstract

Exercise as a Vital Sign: A Quasi-Experimental Analysis of a Health System Intervention to Collect Patient-Reported Exercise Levels

Authors: Grant RW; Schmittdiel JA; Neugebauer RS; Uratsu CS; Sternfeld B

J Gen Intern Med. 2014 Feb;29(2):341-8. Epub 2013-12-06.

PubMed abstract

Accuracy of hemoglobin A1c imputation using fasting plasma glucose in diabetes research using electronic health records data

Authors: Xu S; Schroeder EB; Shetterly S; Goodrich GK; O'Connor PJ; Steiner JF; Schmittdiel JA; Desai J; Pathak RD; Neugebauer R; Butler MG; Kirchner L; Raebel MA

Stat Optim Inf Comput. 2014;2(2):93-104.

Impact of Specific Glucose-Control Strategies on Microvascular and Macrovascular Outcomes in 58,000 Adults With Type 2 Diabetes

Authors: Neugebauer R; Fireman B; Roy JA; O'Connor PJ

Diabetes Care. 2013 Nov;36(11):3510-6. Epub 2013-07-22.

PubMed abstract

Implementation of an outpatient electronic health record and emergency department visits, hospitalizations, and office visits among patients with diabetes

Authors: Reed M; Huang J; Brand R; Graetz I; Neugebauer R; Fireman B; Jaffe M; Ballard DW; Hsu J

JAMA. 2013 Sep 11;310(10):1060-5.

PubMed abstract

Super learning to hedge against incorrect inference from arbitrary parametric assumptions in marginal structural modeling

Authors: Neugebauer R; Fireman B; Roy JA; Raebel MA; Nichols GA; O'Connor PJ

J Clin Epidemiol. 2013 Aug;66(8 Suppl):S99-109.

PubMed abstract

Health-Plan and Employer-Based Wellness Programs to Reduce Diabetes Risk: The Kaiser Permanente Northern California NEXT-D Study

Authors: Schmittdiel JA; Brown SD; Neugebauer R; Adams SR; Adams AS; Wiley D; Ferrara A

Prev Chronic Dis. 2013 Jan;10:E15.

PubMed abstract

Patient Satisfaction and Perceived Success with a Telephonic Health Coaching Program: The Natural Experiments for Translation in Diabetes (NEXT-D) Study, Northern California, 2011

Authors: Adams SR; Goler NC; Sanna RS; Boccio M; Bellamy DJ; Brown SD; Neugebauer RS; Ferrara A; Wiley DM; Schmittdiel JA

Prev Chronic Dis. 2013;10:E179. Epub 2013-10-31.

PubMed abstract

Causal inference in epidemiological studies with strong confounding

Authors: Moore KL; Neugebauer R; van der Laan MJ; Tager IB

Stat Med. 2012 Jun 15;31(13):1380-404. Epub 2012 Feb 23.

PubMed abstract

Dynamic marginal structural modeling to evaluate the comparative effectiveness of more or less aggressive treatment intensification strategies in adults with type 2 diabetes

Authors: Neugebauer R; Fireman B; Roy JA; O'Connor PJ; Selby JV

Pharmacoepidemiol Drug Saf. 2012 May;21 Suppl 2:99-113.

PubMed abstract

HIV Infection, Immunodeficiency, Viral Replication, and the Risk of Cancer

Authors: Silverberg MJ; Chao C; Leyden WA; Xu L; Horberg MA; Klein D; Towner WJ; Dubrow R; Quesenberry CP Jr; Neugebauer RS; Abrams DI

Cancer Epidemiol Biomarkers Prev. 2011 Dec;20(12):2551-9. Epub 2011 Nov 22.

PubMed abstract

Predictors of patient satisfaction with mohs surgery: analysis of preoperative, intraoperative, and postoperative factors in a prospective cohort

Authors: Asgari MM; Warton EM; Neugebauer R; Chren MM

Arch Dermatol. 2011 Dec;147(12):1387-94.

PubMed abstract

Robust extraction of covariate information to improve estimation efficiency in randomized trials

Authors: Moore KL; Neugebauer R; Valappil T; Laan MJ

Stat Med. 2011 Aug 30;30(19):2389-408. Epub 2011 Jul 12.

PubMed abstract

Ambient ozone concentrations and cardiac mortality in Southern California 1983-2000: application of a new marginal structural model approach

Authors: Moore K; Neugebauer R; Lurmann F; Hall J; Brajer V; Alcorn S; Tager I

Am J Epidemiol. 2010 Jun 1;171(11):1233-43. Epub 2010 May 3.

PubMed abstract

Cohort Profile: The Diabetes Study of Northern California (DISTANCE)–objectives and design of a survey follow-up study of social health disparities in a managed care population

Authors: Moffet HH; Adler N; Schillinger D; Ahmed AT; Laraia B; Selby JV; Neugebauer R; Liu JY; Parker MM; Warton M; Karter AJ

Int J Epidemiol. 2009 Feb;38(1):38-47. Epub 2008 Mar 7.

PubMed abstract

Causal inference in longitudinal studies with history-restricted marginal structural models

Authors: Neugebauer R1; van der Laan MJ; Joffe MM; Tager IB;

​Electron J Stat. 2007 Jan 1;1:119-154.

PubMed abstract

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