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Lori C. Sakoda, PhD


Kaiser Permanente Division of Research
2000 Broadway
Oakland, CA 94612

(510) 891-3677 (phone)
Kaiser Permanente Researcher Profiles

Lori C. Sakoda, MPH, PhD, is a research scientist of the Kaiser Permanente Northern California Division of Research and an affiliate investigator of the Division of Public Health Sciences at the Fred Hutchinson Cancer Research Center. Her research interests currently encompass identifying genetic and environmental determinants of risk and prognosis for cancer, particularly of the lung. She is also interested in understanding the basis for observed differences in cancer incidence and outcomes by sex and race/ethnicity.

Current Position(s):

  • Research Scientist II, Division of Research, Kaiser Permanente Northern California
  • Affiliate Investigator, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center

Section Affiliations:

Primary Research Interests:

  • Cancer epidemiology and prevention
  • Genetic determinants of cancer risk, progression, and treatment response
  • Racial/ethnic and sex differences in cancer

    Identifying Barriers to Lung Cancer Screening among Asian Americans

    This study will identify key barriers to lung cancer screening as well as develop tailored strategies and materials to increase the uptake of lung cancer screening and smoking cessation services among Asian Americans.
    Investigator: Sakoda, Lori
    Funder: Tobacco-Related Disease Research Program

    What Factors Affect Time to Surgery for Lung Cancer and Moderate its Associations with Patient Outcomes

    This study will determine factors that influence time to surgery and its associations with outcomes in patients with early-stage non-small cell lung cancer.
    Investigator: Sakoda, Lori
    Funder: TPMG Delivery Science Projects Program

    Utilization and Impact of Extended-Interval Dosing of Immunotherapy on Outcomes in Patients with Locally Advanced NSCLC

    This study will evaluate the utilization and dosing of durvalumab and associations with treatment outcomes among patients with unresectable stage III non-small cell lung cancer in an integrated health care system.
    Investigator: Sakoda, Lori
    Funder: AstraZeneca PLC

    Multilevel Determinants of Racial/Ethnic Disparities in Lung Cancer Screening Utilization

    Lung cancer screening has been underutilized nationally to date, with growing evidence suggesting that screening rates differ by race. This research aims to identify multilevel factors that influence disparities in utilization of lung cancer screening from eligibility determination to screening initiation.
    Investigator: Sakoda, Lori
    Funder: National Cancer Institute

    Comparative Effectiveness of Pretreatment Lung Cancer Nodal Staging

    The proposed project will determine whether a guideline-recommended nodal staging strategy is superior to a guideline-discordant nodal staging strategy, and whether a validated risk-based nodal staging strategy that reduces unnecessary biopsies is an equivalent alternative to a guideline-recommended nodal staging strategy in terms of patient outcomes and costs.
    Investigator: Sakoda, Lori
    Funder: National Cancer Institute

    Disparities in REsults of Immune Checkpoint Inhibitor Treatment (DiRECT): A Prospective Cohort Study of Cancer Survivors Treated with anti-PD-1/anti-PD-L1 in a Community Oncology Setting

    This project will establish a prospective cohort of white and Black cancer patients treated with immune checkpoint inhibitors, leveraging the NCI Community Oncology Research Program network infrastructure, to investigate racial differences in immune-related adverse events and their predictors, treatment delay and discontinuation, and short- and long-term patient outcomes.
    Investigator: Sakoda, Lori
    Funder: National Cancer Institute

    Leveraging Diversity in Cancer Epidemiology Cohorts and Novel Methods to Improve Polygenic Risk Scores

    Inadequate representation of diverse racial/ethnic populations in genetic studies is hindering the translational potential of polygenic risk scores (PRS) in cancer risk prediction. To address this shortcoming, we aim to construct and evaluate PRS for cancer and estimate the absolute risk of cancer explained by PRS and non-genetic factors across multiethnic populations.
    Investigator: Sakoda, Lori
    Funder: National Cancer Institute

    Understanding Racial/Ethnic Disparities in Lung Cancer Screening Utilization

    This study proposes to understand patterns and multilevel determinants of racial/ethnic disparities in Lung Cancer Screening utilization from 2017 onward at KPNC.
    Investigator: Sakoda, Lori
    Funder: Northern California Community Benefit Programs

    Assessing Adherence to Follow-Up Care After Low-Dose Computed Tomography Screening for Lung Cancer

    With the recent implementation of lung cancer screening in community-based practice, little is currently known about utilization patterns and outcomes in patients following the initial low-dose computed tomography (CT) screening exam. The primary goals of this study are to 1) examine adherence to recommended follow-up based on initial low-dose CT screening exam results and 2) identify factors associated with adherence (versus non-adherence) to recommended follow-up.
    Investigator: Sakoda, Lori
    Funder: Northern California Community Benefit Programs

    Evaluating a Risk Prediction Model for Lung Cancer

    Screening with low-dose computed tomography (LDCT) presents an opportunity to improve early detection and reduce mortality from lung cancer. However, the potential harms of LDCT screening, including frequent false-positive findings that lead to unnecessary procedures and repeated radiation exposure, have raised concerns. Implementing targeted screening of persons at highest predicted risk for lung cancer may minimize such harms, but empirical evidence to support more personalized risk-based screening remains limited. This study presents a mentored career development plan encompassing training and research activities for establishing independence as a translational cancer epidemiologist, with a primary focus on early detection and management of lung cancer. The goal of the proposed research is to evaluate whether the most predictive and clinically-oriented risk model for lung cancer to date can be validated, extended and applied to aid decision-making about LDCT screening.
    Investigator: Sakoda, Lori
    Funder: National Cancer Institute
    No results found matching criteria

    Genome-wide interaction study with smoking for colorectal cancer risk identifies novel genetic loci related to tumor suppression, inflammation and immune response

    Author(s): Carreras-Torres, Robert; Scacheri, Peter C; Gauderman, W James; et al.

    Cancer Epidemiol Biomarkers Prev. 2022 Dec 28.

    PubMed abstract

    Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

    Author(s): Fernandez-Rozadilla, Ceres; Pharoah, Paul; Gago-Dominguez, Manuela; Peters, Ulrike; et al.

    Nat Genet. 2022 Dec 20.

    PubMed abstract

    Body Mass Index and Molecular Subtypes of Colorectal Cancer

    Author(s): Murphy, Neil; Schoen, Robert E; Campbell, Peter T; et al.

    J Natl Cancer Inst. 2022 Nov 29.

    PubMed abstract

    Interactions between folate intake and genetic predictors of gene expression levels associated with colorectal cancer risk

    Author(s): Haas, Cameron B; Slattery, Martha L; Hsu, Li; et al.

    Sci Rep. 2022 Nov 07;12(1):18852. Epub 2022-11-07.

    PubMed abstract

    Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies

    Author(s): Cavazos, Taylor B; Van Den Eeden, Stephen; Corley, Douglas A; Kushi, Lawrence H; Regeneron Genetics Center,; Jorgenson, Eric; Witte, John S; Witte, John S; et al.

    BMC Med. 2022 10 06;20(1):332. Epub 2022-10-06.

    PubMed abstract

    Sociodemographic and clinical characteristics associated with never-smoking status in patients with lung cancer: findings from a large integrated health system

    Author(s): Banks, Kian C; Sumner, Eric T; Alabaster, Amy; Hsu, Diana S; Quesenberry, Charles P; Sakoda, Lori C; Velotta, Jeffrey B

    Transl Cancer Res. 2022 Oct;11(10):3522-3534.

    PubMed abstract

    Fostering a High-Functioning Team in Cancer Care Using the 4R Oncology Model: Assessment in a Large Health System and a Blueprint for Other Institutions

    Author(s): Liu, Raymond; Abbe, Thea; Sprague, Sharon Likely; Trosman, Julia R; et al.

    JCO Oncol Pract. 2022 Sep 30:OP2200287.

    PubMed abstract

    Electronic cigarette use and risk of COVID-19 among young adults without a history of cigarette smoking

    Author(s): Young-Wolff, Kelly C; Slama, Natalie E; Alexeeff, Stacey E; Prochaska, Judith J; Fogelberg, Renee; Sakoda, Lori C

    Prev Med. 2022 09;162:107151. Epub 2022-07-06.

    PubMed abstract

    Genome-Wide Interaction Analysis of Genetic Variants with Menopausal Hormone Therapy for Colorectal Cancer Risk

    Author(s): Tian, Yu; Schoen, Robert E; Chang-Claude, Jenny; et al.

    J Natl Cancer Inst. 2022 08 08;114(8):1135-1148.

    PubMed abstract

    Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer

    Author(s): Byun, Jinyoung; Spitz, Margaret; Amos, Christopher I; et al.

    Nat Genet. 2022 Aug;54(8):1167-1177. Epub 2022-08-01.

    PubMed abstract

    Facilitating Adherence to Annual Screening for Lung Cancer: Are Program-Level Interventions Enough?

    Author(s): Sakoda, Lori C; Gould, Michael K

    Chest. 2022 07;162(1):8-10.

    PubMed abstract

    Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region

    Author(s): Jordahl, Kristina M; Scacheri, Peter C; Peters, Ulrike; et al.

    Cancer Epidemiol Biomarkers Prev. 2022 05 04;31(5):1077-1089.

    PubMed abstract

    Genetic variants associated with circulating C-reactive protein levels and colorectal cancer survival: Sex- and lifestyle factors- specific associations

    Author(s): Huang, Yuhan; Schoen, Robert E; Newcomb, Polly A; et al.

    Int J Cancer. 2022 05 01;150(9):1447-1454. Epub 2022-01-13.

    PubMed abstract

    Genetic associations and architecture of asthma-chronic obstructive pulmonary disease overlap

    Author(s): John, Catherine; Iribarren, Carlos; Tesfaigzi, Yohannes; Tobin, Martin D; et al.

    Chest. 2022 05;161(5):1155-1166. Epub 2022-01-31.

    PubMed abstract

    Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study

    Author(s): Archambault, Alexi N; Lee, Jeffrey K; Slattery, Martha L; Hsu, Li; Hayes, Richard B; et al.

    J Natl Cancer Inst. 2022 04 11;114(4):528-539.

    PubMed abstract

    Cigarette Smoking and Risk of SARS-CoV-2 infection and Disease Severity Among Adults in an Integrated Health Care System in California

    Author(s): Young-Wolff KC; Slama N; Alexeeff SE; Sakoda LC; Fogelberg R; Myers LC; Campbell CI; Adams AS; Prochaska JJ

    Nicotine Tob Res. 2022 Apr 03.

    PubMed abstract

    Accounting for EGFR mutations in epidemiological analyses of non-small cell lung cancers: Examples based on the International Lung Cancer Consortium data

    Author(s): Schmid, Sabine; Brennan, Paul; Liu, Geoffrey; et al.

    Cancer Epidemiol Biomarkers Prev. 2022 Mar 01;31(3):679-687.

    PubMed abstract

    The Friends of Cancer Research Real World Data (RWD) Collaboration Pilot 2.0: Methodological Recommendations from Oncology Case Studies

    Author(s): Rivera, Donna R; Mishra Kalyani, Pallavi S; Sharon, Elad; Allen, Jeff D; et al.

    Clin Pharmacol Ther. 2022 01;111(1):283-292. Epub 2021-11-11.

    PubMed abstract

    Adherence to Lung Cancer Screening: What Exactly Are We Talking About?

    Author(s): Sakoda, Lori C; Henderson, Louise M; Rivera, M Patricia

    Ann Am Thorac Soc. 2021 12;18(12):1951-1952.

    PubMed abstract

    Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study

    Author(s): Nounu, Aayah; Slattery, Martha L; Relton, Caroline L; et al.

    Nutrients. 2021 11 21;13(11). Epub 2021-11-21.

    PubMed abstract

    Survival Associated With Consolidated Multidisciplinary Care in Head and Neck Cancer: A Retrospective Cohort Study

    Author(s): Meltzer, Charles; Nguyen, Nathalie T; Zhang, Jie; Aguilar, Jillian; Blatchins, Maruta A; Quesenberry, Charles P; Wang, Yan; Sakoda, Lori C

    Otolaryngol Head Neck Surg. 2021 Nov 09:1945998211057852.

    PubMed abstract

    Smoking Behavior and Prognosis After Colorectal Cancer Diagnosis: A Pooled Analysis of 11 Studies

    Author(s): Alwers, Elizabeth; White, Emily; Brenner, Hermann; et al.

    JNCI Cancer Spectr. 2021 10;5(5). Epub 2021-08-31.

    PubMed abstract

    Association Between Smoking and Molecular Subtypes of Colorectal Cancer

    Author(s): Wang, Xiaoliang; Schoen, Robert E; Peters, Ulrike; et al.

    JNCI Cancer Spectr. 2021 08;5(4). Epub 2021-06-14.

    PubMed abstract

    Genetic architectures of proximal and distal colorectal cancer are partly distinct

    Author(s): Huyghe, Jeroen R; Schumacher, Fredrick R; Campbell, Peter T; Peters, Ulrike; et al.

    Gut. 2021 07;70(7):1325-1334. Epub 2021-02-25.

    PubMed abstract

    Genetically predicted circulating C-reactive protein concentration and colorectal cancer survival: A Mendelian randomization consortium study

    Author(s): Hua, Xinwei; Schoen, Robert E; Newcomb, Polly A; et al.

    Cancer Epidemiol Biomarkers Prev. 2021 07;30(7):1349-1358. Epub 2021-05-10.

    PubMed abstract

    Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent: a Mendelian randomization study

    Author(s): Tsilidis, Konstantinos K; Schafmayer, Clemens; Gunter, Marc J; et al.

    Am J Clin Nutr. 2021 06 01;113(6):1490-1502.

    PubMed abstract

    Nongenetic Determinants of Risk for Early-Onset Colorectal Cancer

    Author(s): Archambault, Alexi N; Sandler, Robert S; Hayes, Richard B; et al.

    JNCI Cancer Spectr. 2021 06;5(3). Epub 2021-05-20.

    PubMed abstract

    Two-Sample Mendelian Randomization Analysis of Associations Between Periodontal Disease and Risk of Cancer

    Author(s): Corlin, Laura; Vodi?ka, Pavel; Michaud, Dominique S; et al.

    JNCI Cancer Spectr. 2021 06;5(3). Epub 2021-04-19.

    PubMed abstract

    An Intervention to Tag Findings Suspicious for Lung Cancer on Chest Computed Tomography Has Good Sensitivity and Number Needed to Diagnose

    Author(s): Dusendang, Jennifer R; Sakoda, Lori C; Urbania, Thomas H; Ely, Sora; Osinski, Todd; Patel, Ashish; Herrinton, Lisa J

    Perm J. 2021 05 12;25. Epub 2021-05-12.

    PubMed abstract

    Ten-year Thyroid Cancer Incidence in an Integrated Healthcare Delivery System

    Author(s): Kim, Stephanie J; Durr, Megan L; Darbinian, Jeanne A; Sakoda, Lori C; Meltzer, Charles J; Arzumanyan, Hasmik; Wang, Kevin H; Lin, Jonathan K; Gurushanthaiah, Deepak; Lo, Joan C

    Perm J. 2021 05;25.

    PubMed abstract

    A large-scale association study detects novel rare variants, risk genes, functional elements, and polygenic architecture of prostate cancer susceptibility

    Author(s): Emami, Nima C; Habel, Laurel A; Shan, Jun; Kvale, Mark N; Risch, Neil; Witte, John S; Witte, John S; et al.

    Cancer Res. 2021 04 01;81(7):1695-1703. Epub 2020-12-08.

    PubMed abstract

    Patterns and Factors Associated With Adherence to Lung Cancer Screening in Diverse Practice Settings

    Author(s): Sakoda, Lori C; Minowada, George; Henderson, Louise M; et al.

    JAMA Netw Open. 2021 04 01;4(4):e218559. Epub 2021-04-01.

    PubMed abstract

    Response to Li and Hopper

    Author(s): Thomas, Minta; Hoffmeister, Michael; van Duijnhoven, Franzel J B; Peters, Ulrike; Hsu, Li; et al.

    Am J Hum Genet. 2021 03 04;108(3):527-529.

    PubMed abstract

    Identifying novel susceptibility genes for colorectal cancer risk from a transcriptome-wide association study of 125,478 subjects

    Author(s): Guo, Xingyi; Schafmayer, Clemens; Zheng, Wei; et al.

    Gastroenterology. 2021 03;160(4):1164-1178.e6. Epub 2020-10-12.

    PubMed abstract

    A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer

    Author(s): Nounu, Aayah; Slattery, Martha L; Relton, Caroline L; et al.

    Cancer Epidemiol Biomarkers Prev. 2021 03;30(3):564-575. Epub 2020-12-14.

    PubMed abstract

    Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts

    Author(s): Graff, Rebecca E; Blatchins, Maruta; Kushi, Lawrence H; Ziv, Elad; Jorgenson, Eric; Witte, John S; Sakoda, Lori C; et al.

    Nat Commun. 2021 02 12;12(1):970. Epub 2021-02-12.

    PubMed abstract

    Association of body mass index with colorectal cancer risk by genome-wide variants

    Author(s): Campbell PT; Slattery ML; Peters U; et al.

    J Natl Cancer Inst. 2021 01 04;113(1):38-47.

    PubMed abstract

    Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

    Author(s): Bull, Caroline J; Schafmayer, Clemens; Gunter, Marc J; et al.

    BMC Med. 2020 12 17;18(1):396. Epub 2020-12-17.

    PubMed abstract

    Genetic Variants in the Regulatory T cell-Related Pathway and Colorectal Cancer Prognosis

    Author(s): Neumeyer, Sonja; Schoen, Robert E; Chang-Claude, Jenny; et al.

    Cancer Epidemiol Biomarkers Prev. 2020 12;29(12):2719-2728. Epub 2020-10-02.

    PubMed abstract

    Standardized reporting and management of suspicious findings on chest computed tomography is associated with improved lung cancer diagnosis in an observational study

    Author(s): Urbania TH; Dusendang JR; Herrinton LJ; Alexeeff S; Corley DA; Ely S; Patel A; Osinski T; Sakoda LC

    Chest. 2020 11;158(5):2211-2220. Epub 2020-06-17.

    PubMed abstract

    Early Screening of African Americans (45-50 Years Old) in a Fecal Immunochemical Test-based Colorectal Cancer Screening Program

    Author(s): Levin TR; Jensen CD; Chawla NM; Sakoda LC; Lee JK; Zhao WK; Landau MA; Herm A; Eby E; Quesenberry CP; Corley DA

    Gastroenterology. 2020 11;159(5):1695-1704.e1. Epub 2020-07-20.

    PubMed abstract

    Intake of dietary fruit, vegetables, and fiber and risk of colorectal cancer according to molecular subtypes: A pooled analysis of 9 studies

    Author(s): Hidaka, Akihisa; Barfield, Richard; Peters, Ulrike; et al.

    Cancer Res. 2020 10 15;80(20):4578-4590. Epub 2020-08-14.

    PubMed abstract

    Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk

    Author(s): Sieh, Weiva; Sakoda, Lori C; Jorgenson, Eric; Whittemore, Alice S; Habel, Laurel A; et al.

    Nat Commun. 2020 10 09;11(1):5116. Epub 2020-10-09.

    PubMed abstract

    Pathway Analysis of Renal Cell Carcinoma Genome-Wide Association Studies Identifies Novel Associations

    Author(s): Purdue, Mark P; Thai, Khanh; Yu, Kai; et al.

    Cancer Epidemiol Biomarkers Prev. 2020 10;29(10):2065-2069. Epub 2020-07-30.

    PubMed abstract

    Addressing Disparities in Lung Cancer Screening Eligibility and Healthcare Access. An Official American Thoracic Society Statement

    Author(s): Rivera, M Patricia; Wiener, Renda Soylemez; Aldrich, Melinda C; et al.

    Am J Respir Crit Care Med. 2020 10 01;202(7):e95-e112.

    PubMed abstract

    Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts

    Author(s): Rashkin, Sara R; Blatchins, Maruta A; Emami, Nima C; Meyers, Travis J; Ziv, Elad; Hoffmann, Thomas J; Witte, John S; Witte, John S; et al.

    Nat Commun. 2020 09 04;11(1):4423. Epub 2020-09-04.

    PubMed abstract

    Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk

    Author(s): Thomas, Minta; Hoffmeister, Michael; van Duijnhoven, Franzel J B; Peters, Ulrike; Hsu, Li; et al.

    Am J Hum Genet. 2020 09 03;107(3):432-444. Epub 2020-08-05.

    PubMed abstract

    Circulating bilirubin levels and risk of colorectal cancer: serological and Mendelian randomization analyses

    Author(s): Seyed Khoei, Nazlisadat; Schafmayer, Clemens; Freisling, Heinz; et al.

    BMC Med. 2020 09 03;18(1):229. Epub 2020-09-03.

    PubMed abstract

    Telomere maintenance variants and survival after colorectal cancer: Smoking- and sex-specific associations

    Author(s): Yin H; Slattery ML; Newcomb PA; et al.

    Cancer Epidemiol Biomarkers Prev. 2020 09;29(9):1817-1824. Epub 2020-06-25.

    PubMed abstract

    Postmenopausal Hormone Therapy and Colorectal Cancer Risk by Molecularly Defined Subtypes and Tumor Location

    Author(s): Labadie, Julia D; Slattery, Martha L; Newcomb, Polly A; et al.

    2020 Aug;4(5):pkaa042. Epub 2020-05-19.

    PubMed abstract

    Genetic predictors of circulating 25-hydroxyvitamin D and prognosis after colorectal cancer

    Author(s): Neumeyer S; Schoen RE; Chang-Claude J; et al.

    Cancer Epidemiol Biomarkers Prev. 2020 06;29(6):1128-1134. Epub 2020-03-18.

    PubMed abstract

    Alcohol and tobacco use in relation to mammographic density in 23,456 women

    Author(s): McBride RB; Song X; McGuire V; Sieh W; Sieh W; et al.

    Cancer Epidemiol Biomarkers Prev. 2020 05;29(5):1039-1048. Epub 2020-02-17.

    PubMed abstract

    Functional informed genome-wide interaction analysis of body mass index, diabetes and colorectal cancer risk

    Author(s): Xia Z; Albanes D; Peters U; et al.

    Cancer Med. 2020 05;9(10):3563-3573. Epub 2020-03-24.

    PubMed abstract

    Cumulative Burden of Colorectal Cancer-Associated Genetic Variants is More Strongly Associated With Early-onset vs Late-onset Cancer

    Author(s): Archambault AN; Lansdorp-Vogelaar I; Hsu L; Hayes RB; et al.

    Gastroenterology. 2020 04;158(5):1274-1286.e12. Epub 2019-12-19.

    PubMed abstract

    Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses

    Author(s): Murphy N; Schafmayer C; Gunter MJ; et al.

    Gastroenterology. 2020 04;158(5):1300-1312.e20. Epub 2019-12-27.

    PubMed abstract

    Mendelian randomization of circulating polyunsaturated fatty acids and colorectal cancer risk

    Author(s): Khankari NK; Schafmayer C; Zheng W; et al.

    Cancer Epidemiol Biomarkers Prev. 2020 04;29(4):860-870. Epub 2020-02-12.

    PubMed abstract

    Risk of Mortality between Untreated and Treated Papillary Thyroid Cancer: A Matched Cohort Analysis

    Author(s): Lin JK; Sakoda LC; Darbinian J; Socarras M; Chiao W; Calixto N; Quesenberry C; Gurushanthaiah D; Wang KH; Durr M

    Ann Otol Rhinol Laryngol. 2020 Mar;129(3):265-272. Epub 2019-10-28.

    PubMed abstract

    COPD and lung cancer incidence in the Women's Health Initiative Observational Study: A brief report

    Author(s): Nagasaka M; Lehman A; Chlebowski R; Haynes BM; Ho G; Patel M; Sakoda LC; Schwartz AG; Simon MS; Cote ML

    Lung Cancer. 2020 03;141:78-81. Epub 2020-01-07.

    PubMed abstract

    Understanding the natural history of papillary thyroid cancer: Case series

    Author(s): Lin JK; Sakoda LC; Darbinian J; Chiao W; Calixto N; Gurushanthaiah D; Wang KH; Durr M

    Head Neck. 2019 12;41(12):4164-4170. Epub 2019-10-04.

    PubMed abstract

    Factors associated with employment discontinuation among older and working age survivors of oropharyngeal cancer

    Author(s): Check DK; Hutcheson KA; Poisson LM; Pocobelli G; Sakoda LC; Zaveri J; Chang SS; Chubak J

    Head Neck. 2019 11;41(11):3948-3959. Epub 2019-09-06.

    PubMed abstract

    An Exploratory Analysis of Real-World End Points for Assessing Outcomes Among Immunotherapy-Treated Patients With Advanced Non-Small-Cell Lung Cancer

    Author(s): Stewart M; Mansfield AS; Torres AZ; Allen J; et al.

    JCO Clin Cancer Inform. 2019 07;3:1-15.

    PubMed abstract

    Telomere length and socioeconomic status at neighborhood and individual levels among 80,000 adults in the Genetic Epidemiology Research on Adult Health and Aging cohort

    Author(s): Alexeeff, Stacey E; Kvale, Mark N; Ranatunga, Dilrini K; Quesenberry, Charles P; Van Den Eeden, Stephen K; Van Den Eeden, Stephen K; et al.

    Environ Epidemiol. 2019 Jun;3(3):e049. Epub 2019-05-01.

    PubMed abstract

    Effectiveness of a Patient Education Class to Enhance Knowledge about Lung Cancer Screening: a Quality Improvement Evaluation

    Author(s): Sakoda LC; Meyer MA; Chawla N; Sanchez MA; Blatchins MA; Nayak S; San K; Zin GK; Minowada G; Permanente Medical Group Lung Cancer Screening Task Force

    J Cancer Educ. 2019 May 09.

    PubMed abstract

    Discovery of common and rare genetic risk variants for colorectal cancer

    Author(s): Huyghe JR; Campbell PT; Schafmayer C; Peters U; et al.

    Nat Genet. 2019 01;51(1):76-87. Epub 2018-12-03.

    PubMed abstract

    Examining the role of access to care: Racial/ethnic differences in receipt of resection for early-stage non-small cell lung cancer among integrated system members and non-members

    Author(s): Check DK; Albers KB; Uppal KM; Suga JM; Adams AS; Habel LA; Quesenberry CP; Sakoda LC

    Lung Cancer. 2018 Nov;125:51-56. Epub 2018-09-11.

    PubMed abstract

    The TGFβ-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs

    Author(s): Pellatt AJ; Mullany LE; Herrick JS; Sakoda LC; Wolff RK; Samowitz WS; Slattery ML

    J Transl Med. 2018 07 09;16(1):191. Epub 2018-07-09.

    PubMed abstract

    Mutation analysis of adenomas and carcinomas of the colon: early and late drivers

    Author(s): Wolff RK; Hoffman MD; Wolff EC; Herrick JS; Sakoda LC; Samowitz WS; Slattery ML

    Genes Chromosomes Cancer. 2018 07;57(7):366-376. Epub 2018-04-30.

    PubMed abstract

    The p53-signaling pathway and colorectal cancer: Interactions between downstream p53 target genes and miRNAs

    Author(s): Slattery ML; Mullany LE; Wolff RK; Sakoda LC; Samowitz WS; Herrick JS

    Genomics. 2018 Jun 01.

    PubMed abstract

    MicroRNA-messenger RNA interactions involving JAK-STAT signaling genes in colorectal cancer

    Author(s): Mullany LE; Herrick JS; Sakoda LC; Samowitz W; Stevens JR; Wolff RK; Slattery ML

    Genes Cancer. 2018 May;9(5-6):232-246.

    PubMed abstract

    Dysregulated genes and miRNAs in the apoptosis pathway in colorectal cancer patients

    Author(s): Slattery ML; Mullany LE; Sakoda LC; Wolff RK; Samowitz WS; Herrick JS

    Apoptosis. 2018 04;23(3-4):237-250.

    PubMed abstract

    The NF-κB signalling pathway in colorectal cancer: associations between dysregulated gene and miRNA expression

    Author(s): Slattery ML; Mullany LE; Sakoda L; Samowitz WS; Wolff RK; Stevens JR; Herrick JS

    J Cancer Res Clin Oncol. 2018 Feb;144(2):269-283. Epub 2017-11-29.

    PubMed abstract

    Expression of Wnt-signaling pathway genes and their associations with miRNAs in colorectal cancer

    Author(s): Slattery ML; Mullany LE; Sakoda LC; Samowitz WS; Wolff RK; Stevens JR; Herrick JS

    Oncotarget. 2018 Jan 19;9(5):6075-6085. Epub 2017-12-23.

    PubMed abstract

    The MAPK-Signaling Pathway in Colorectal Cancer: Dysregulated Genes and Their Association With MicroRNAs

    Author(s): Slattery ML; Mullany LE; Sakoda LC; Wolff RK; Samowitz WS; Herrick JS

    Cancer Inform. 2018;17:1176935118766522. Epub 2018-03-26.

    PubMed abstract

    miRNA involvement in cell cycle regulation in colorectal cancer cases

    Author(s): Mullany LE; Herrick JS; Sakoda LC; Samowitz W; Stevens JR; Wolff RK; Slattery ML

    Genes Cancer. 2018 Jan;9(1-2):53-65.

    PubMed abstract

    Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients: a multicenter study from the International Lung Cancer Consortium

    Author(s): Lohavanichbutr P; Amos CI; Chen C; et al.

    Clin Cancer Res. 2017 Dec 15;23(24):7550-7557. Epub 2017-10-03.

    PubMed abstract

    Monitoring Lung Cancer Screening Utilization and Outcomes in Four Cancer Research Network Sites

    Author(s): Gould MK; Sakoda LC; Ritzwoller DP; Simoff MJ; Neslund-Dudas CM; Kushi LH; Carter-Harris L; Feigelson HS; Minowada G; Doria-Rose VP

    Ann Am Thorac Soc. 2017 Dec;14(12):1827-1835.

    PubMed abstract

    Applying Risk Prediction Models to Optimize Lung Cancer Screening: Current Knowledge, Challenges, and Future Directions

    Author(s): Sakoda LC; Henderson LM; Caverly TJ; Wernli KJ; Katki HA

    Curr Epidemiol Rep. 2017 Dec;4(4):307-320. Epub 2017-10-24.

    PubMed abstract

    The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer

    Author(s): Slattery ML; Herrick JS; Mullany LE; Samowitz WS; Sevens JR; Sakoda L; Wolff RK

    Genes Chromosomes Cancer. 2017 11;56(11):769-787. Epub 2017-07-30.

    PubMed abstract

    The PI3K/AKT Signaling Pathway: associations of miRNAs with dysregulated gene expression in colorectal cancer

    Author(s): Slattery ML; Mullany LE; Sakoda LC; Wolff RK; Stevens JR; Samowitz WS; Herrick JS

    Mol Carcinog. 2017 Oct 25.

    PubMed abstract

    Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study

    Author(s): Jorgenson E; Thai KK; Hoffmann TJ; Sakoda LC; Kvale MN; Banda Y; Schaefer C; Risch N; Mertens J; Weisner C; Choquet H

    Mol Psychiatry. 2017 Sep;22(9):1359-1367. Epub 2017-05-09.

    PubMed abstract

    Effect of Angiotensin System Inhibitors on Survival in Patients Receiving Chemotherapy for Advanced Non-Small-Cell Lung Cancer

    Author(s): Menter AR; Carroll NM; Sakoda LC; Delate T; Hornbrook MC; Jain RK; Kushi LH; Quinn VP; Ritzwoller DP

    Clin Lung Cancer. 2017 Mar;18(2):189-197.e3. Epub 2016-08-20.

    PubMed abstract

    Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer

    Author(s): Hoffmann TJ; Jorgenson E; Shan J; Chao CR; Risch N; Van Den Eeden SK; Witte JS; Witte JS; et al.

    Nat Commun. 2017 Jan 31;8:14248. Epub 2017-01-31.

    PubMed abstract

    Common coding variants in the HLA-DQB1 region confer susceptibility to age-related macular degeneration

    Author(s): Jorgenson E; Melles RB; Hoffmann TJ; Jia X; Sakoda LC; Kvale MN; Banda Y; Schaefer C; Risch N; Shen L

    Eur J Hum Genet. 2016 Jul;24(7):1049-55. Epub 2016-01-06.

    PubMed abstract

    A large multi-ethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences

    Author(s): Hoffmann TJ; Sakoda LC; Jorgenson E; Graff RE; Aaronson D; Risch N; Witte JS; et al.

    Cancer Discov. 2015 Aug;5(8):878-91. Epub 2015-06-01.

    PubMed abstract

    Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

    Author(s): Kvale MN; Dispensa BP; Jorgenson E; Lao R; Ranatunga D; Shapero M; Walter L; Wong S; Kwok PY; Risch N; et al.

    Genetics. 2015 Aug;200(4):1051-60. Epub 2015-06-19.

    PubMed abstract

    Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

    Author(s): Lapham K; Dispensa BP; Jorgenson E; Ludwig D; Rowell S; Smethurst D; Walter L; Kwok PY; Schaefer C; Blackburn EH; Blackburn EH; et al.

    Genetics. 2015 Aug;200(4):1061-72. Epub 2015-06-19.

    PubMed abstract

    Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

    Author(s): Banda Y; Dispensa BP; Jorgenson E; Ludwig D; Rowell S; Sciortino S; Walter L; Kwok PY; Risch N; Risch N; et al.

    Genetics. 2015 Aug;200(4):1285-95. Epub 2015-06-19.

    PubMed abstract

    Differences in the Genetic Susceptibility to Age-Related Macular Degeneration Clinical Subtypes

    Author(s): Shen L; Hoffmann TJ; Melles RB; Sakoda LC; Kvale MN; Banda Y; Schaefer C; Risch N; Jorgenson E

    Invest Ophthalmol Vis Sci. 2015 Jul;56(8):4290-9.

    PubMed abstract

    Metformin use and lung cancer risk in patients with diabetes

    Author(s): Sakoda LC; Ferrara A; Achacoso NS; Peng T; Ehrlich SF; Quesenberry CP; Habel LA

    Cancer Prev Res (Phila). 2015 Feb;8(2):174-9.

    PubMed abstract

    Imputation of the Rare HOXB13 G84E Mutation and Cancer Risk in a Large Population-Based Cohort

    Author(s): Hoffmann TJ; Shen L; Liu J; Banda Y; Kushi LH; Quesenberry CP; Schaefer C; Van Den Eeden SK; Risch N; Witte JS; Witte JS; et al.

    PLoS Genet. 2015 Jan;11(1):e1004930. Epub 2015-01-28.

    PubMed abstract

    Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia

    Author(s): Setiawan VW; Doherty J; Le Marchand L; et al.

    Carcinogenesis. 2014 Sep;35(9):2068-73. Epub 2014-05-15.

    PubMed abstract

    Turning of COGS moves forward findings for hormonally mediated cancers

    Author(s): Sakoda LC; Jorgenson E; Witte JS

    Nat Genet. 2013 Apr;45(4):345-8.

    PubMed abstract

    DNA repair genotype and lung cancer risk in the beta-carotene and retinol efficacy trial

    Author(s): Doherty JA; Sakoda LC; Loomis MM; Barnett MJ; Julianto L; Thornquist MD; Neuhouser ML; Weiss NS; Goodman GE; Chen C

    Int J Mol Epidemiol Genet. 2013;4(1):11-34. Epub 2013 Mar 18.

    PubMed abstract

    HOXB13:IL17BR and molecular grade index and risk of breast cancer death among patients with lymph node-negative invasive disease

    Author(s): Habel LA; Sakoda LC; Achacoso N; Ma XJ; Erlander MG; Sgroi DC; Fehrenbacher L; Greenberg D; Quesenberry CP

    Breast Cancer Res. 2013;15(2):R24. Epub 2013-03-14.

    PubMed abstract

    Screening for colorectal neoplasms with new fecal occult blood tests: update on performance characteristics

    Author(s): Allison JE; Tucker JP; Selby JV; et al.

    J Natl Cancer Inst. 2007 Oct 3;99(19):1462-70. Epub 2007 Sep 25.

    PubMed abstract