CARDIA Brain MRI Microbiome Study

Despite growing evidence that gut microbiota may play an important role in phenotypes related to cardiovascular (CVD) risk, there remains a lack of data from large-scale, population-based cohorts, and particularly, among racial minorities at high CVD risk, such as African-Americans. We will address this gap through collection of stool and microbiome analysis in a sample of CARDIA participants balanced with respect to age and race (African Americans and whites) (n=600, 100 from the Oakland Field Center).
Objectives:
1. To collect stool samples from=100 participants at the Oakland CARDIA field center (600 study-wide).
2. Quantity associations between gut microbial composition and function with cardiometabolic risk factors.

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