Early Vascular Contributions to Dementia Risk in African-Americans

This is a lifecourse study of vascular risk and brain aging in a well-characterized population of 1,200 elderly African-Americans that will close the gap in knowledge regarding midlife risk and protective factors for cognitive decline. The data collected, in conjunction with extensive electronic medical records spanning decades, will allow for a cost-effective, efficient approach for an observational study of cumulative vascular risk and brain aging. Our overall objective is to understand the magnitude of cognitive decline and long-term contributions of vascular disease on cognitive impairment and brain injury in African-Americans, an understudied and rapidly expanding segment of the elderly population.

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