Infrastructure for Pathways, a Prospective Study of Breast Cancer Survivorship

This grant provides core infrastructure support for the Pathways Study (Kushi, PI), a prospective cohort study of breast cancer survivorship and prognosis. Since 2006, the study enrolled 4,505 women diagnosed with invasive breast cancer in KPNC. Activities (Ambrosone, Christine, Roswell Park Cancer Institute, Co-PI) include ongoing follow-up of participants, active and passive ascertainment of outcomes, collection of tumor specimens, linkage to KPNC electronic records, enhancement of area-level data from contextual databases through virtual neighborhood audits, provision of genotypic data from genome-wide assays, and establishment of a community and participant advisory board. These activities enhance the Pathways Study to make it an unparalleled, outstanding resource for studies of breast cancer prognosis.

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