Lifecourse Health, Cerebral Pathology, and Ethnic Disparities in Dementia

Although there are marked ethnic disparities in rates of dementia, almost nothing is known about early-life contributors to dementia in ethnic minority groups, nor if the trajectory of cognitive decline or transition to cognitive impairment varies across ethnic groups. This study leverages a large, diverse sample with over 5 decades of prospectively collected life history and health data to delineate why there are racial and ethnic disparities in dementia and how risk and protective factors and brain mechanisms differ across ethnic and racial groups.

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