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Novel Strategies to Identify G x E Contributions to MS Pathogensis

The goal of the study is to examine potential gene X environment interactions in relation to risk and progression of multiple sclerosis (MS) in a 2,400-person case control dataset. The study will examine family and self-history of other autoimmune disorders, as well as a number of potential environmental risk factors, including obesity, history of depression and stressful life events, exposure to tobacco smoke and other factors, in interaction with polymorphisms in potential candidate genes.

Investigator: Schaefer, Catherine

Funder: National Institute of Environmental Health Sciences

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